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The map label for this gene is glpD2 [H]

Identifier: 146302612

GI number: 146302612

Start: 5906896

End: 5908473

Strand: Direct

Name: glpD2 [H]

Synonym: Fjoh_4885

Alternate gene names: 146302612

Gene position: 5906896-5908473 (Clockwise)

Preceding gene: 146302611

Following gene: 146302613

Centisome position: 96.88

GC content: 36.06

Gene sequence:

>1578_bases
ATGAATCGTTCAGAGCAGTTACTAAAACTACAAAATACCGAAAATTGGGACGTAATAATTATAGGCGGAGGAGCCAGCGG
TTTAGGAACTGCAATTGATGCTGCCAGCCGAGGCTATAAAACCATCTTACTTGAAGCTGTAGATTTTGCCAAAGGAACTT
CCAGCAGAAGTACCAAATTAGTTCATGGCGGTGTACGATATTTGGCGCAGGGAGATGTCCACTTAGTTAGAGAAGCATTA
AAAGAGCGAGGTTTACTGGCACAAAATGCAAATCATTTGGTAAAAAACCAATCTTTTGTTATTCCAAATTACCATTGGTT
AAGCGGTTACTTTTACACCATTGGATTAAAAATTTATGATCTATTATCAGGAGGTTTAAGTTTAGGGAGTTCTAAATATC
TTTCCAAAAAGAAAACTATCGAAATGCTTCCAAATGTAGAAGAAGACGGACTTGTAAATGGTGTTATTTATCATGACGGG
CAATTTGACGATTCTCGTTTGGCTGTAAATCTGGCTCAGACTGCGGTAGAAAACGGAGCTTGTGTTTTAAATTATACAAA
AGTTATTAATTTAATAAAAGATGATAAAAATCAAATCACCGGCGTTCAGGCAGTTGATCAGGAAACCGGAATAAACTATA
ACATAAAAGGTGCAGTTGTAATAAATGCAACAGGAGTTTTTACAAATGCCATCATGAAGCTAAACGATAAAGTTTACAAA
AAATATATCGTGCCGAGTCAGGGAATTCATTTGGTGTTTGATAAATCTTTTCTTCCAGGCGAACATGCTTTGATGATTCC
GAAAACAAAAGATGGAAGAGTTTTATTTGCTGTTCCGTGGCACAATCACGTTGTAGTAGGTACAACCGACACTTTAATAA
AAAAACAAAGTTTAGAACCTATTGCTTTAGAAAGCGAAATTGAATTTGTTTTAGAAACAGCACAGCGATTCCTTGCCAAA
AAACCAACAAGAGCCGATGTATTATCTGTTTTTGCAGGTCTGCGTCCGTTAGCTGCTCCAAAAGAAGAAGGCAGAAGCAC
AAAAGAAGTTTCCAGAAGTCATAAAATTATAGTTTCAGAAACTGGATTGATAACCATAACAGGAGGTAAATGGACTACTT
ACCGAAAAATTGCCGAAGACATCATTGACAAAGCAATACTAAAAGGAAAACTTCCCAAAAAACCTTGTATTACACAAAAC
TTAAGCATTCACGGAAATAAACCTACAACGACTCTTGATAGGGAAAACCACTTGTATATTTATGGTTCTGATATTACAAA
AATACTCCAGCTGCAAGAAAAAGAACCAGAATTAAAAGAAAAACTCCATCTTGATTATGAATTTACATTGGCAGAAATTG
TTTGGGCTGTACGTTATGAAATGGCAAGAACTGTAGATGATATTCTGGCAAGACGTGTTCGATTATTGTTTTTGGATGCC
AGAGCTGCAATTGAAGTATCTGAAAAAACAGCAAGGGTAATTGCAAAAGAACTTGGACATGATGAAAATTGGGTCGCTAA
GGAAATTGCCGATTTTAAAGCGACATCTAAAGGATTTTTTCTCTCTGAATTTCGATAA

Upstream 100 bases:

>100_bases
ATTTTTTTCTACCAATGACACATTCATACGGAATATTTCTTCATCAATTTTTAATTTCATTTCGTTAAGTTTGCTTTAAA
CAAAAAGTCCCGTAAAAAAT

Downstream 100 bases:

>100_bases
GCAGTTCAAAATCAAAGTATATTTTAAACTCCTTCTATTTATGGTTAAAAAATTAGTCTTACAAAAATGCCTCAGCAATA
AAAATATTTAAATCTGAATA

Product: FAD dependent oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 525; Mature: 525

Protein sequence:

>525_residues
MNRSEQLLKLQNTENWDVIIIGGGASGLGTAIDAASRGYKTILLEAVDFAKGTSSRSTKLVHGGVRYLAQGDVHLVREAL
KERGLLAQNANHLVKNQSFVIPNYHWLSGYFYTIGLKIYDLLSGGLSLGSSKYLSKKKTIEMLPNVEEDGLVNGVIYHDG
QFDDSRLAVNLAQTAVENGACVLNYTKVINLIKDDKNQITGVQAVDQETGINYNIKGAVVINATGVFTNAIMKLNDKVYK
KYIVPSQGIHLVFDKSFLPGEHALMIPKTKDGRVLFAVPWHNHVVVGTTDTLIKKQSLEPIALESEIEFVLETAQRFLAK
KPTRADVLSVFAGLRPLAAPKEEGRSTKEVSRSHKIIVSETGLITITGGKWTTYRKIAEDIIDKAILKGKLPKKPCITQN
LSIHGNKPTTTLDRENHLYIYGSDITKILQLQEKEPELKEKLHLDYEFTLAEIVWAVRYEMARTVDDILARRVRLLFLDA
RAAIEVSEKTARVIAKELGHDENWVAKEIADFKATSKGFFLSEFR

Sequences:

>Translated_525_residues
MNRSEQLLKLQNTENWDVIIIGGGASGLGTAIDAASRGYKTILLEAVDFAKGTSSRSTKLVHGGVRYLAQGDVHLVREAL
KERGLLAQNANHLVKNQSFVIPNYHWLSGYFYTIGLKIYDLLSGGLSLGSSKYLSKKKTIEMLPNVEEDGLVNGVIYHDG
QFDDSRLAVNLAQTAVENGACVLNYTKVINLIKDDKNQITGVQAVDQETGINYNIKGAVVINATGVFTNAIMKLNDKVYK
KYIVPSQGIHLVFDKSFLPGEHALMIPKTKDGRVLFAVPWHNHVVVGTTDTLIKKQSLEPIALESEIEFVLETAQRFLAK
KPTRADVLSVFAGLRPLAAPKEEGRSTKEVSRSHKIIVSETGLITITGGKWTTYRKIAEDIIDKAILKGKLPKKPCITQN
LSIHGNKPTTTLDRENHLYIYGSDITKILQLQEKEPELKEKLHLDYEFTLAEIVWAVRYEMARTVDDILARRVRLLFLDA
RAAIEVSEKTARVIAKELGHDENWVAKEIADFKATSKGFFLSEFR
>Mature_525_residues
MNRSEQLLKLQNTENWDVIIIGGGASGLGTAIDAASRGYKTILLEAVDFAKGTSSRSTKLVHGGVRYLAQGDVHLVREAL
KERGLLAQNANHLVKNQSFVIPNYHWLSGYFYTIGLKIYDLLSGGLSLGSSKYLSKKKTIEMLPNVEEDGLVNGVIYHDG
QFDDSRLAVNLAQTAVENGACVLNYTKVINLIKDDKNQITGVQAVDQETGINYNIKGAVVINATGVFTNAIMKLNDKVYK
KYIVPSQGIHLVFDKSFLPGEHALMIPKTKDGRVLFAVPWHNHVVVGTTDTLIKKQSLEPIALESEIEFVLETAQRFLAK
KPTRADVLSVFAGLRPLAAPKEEGRSTKEVSRSHKIIVSETGLITITGGKWTTYRKIAEDIIDKAILKGKLPKKPCITQN
LSIHGNKPTTTLDRENHLYIYGSDITKILQLQEKEPELKEKLHLDYEFTLAEIVWAVRYEMARTVDDILARRVRLLFLDA
RAAIEVSEKTARVIAKELGHDENWVAKEIADFKATSKGFFLSEFR

Specific function: Conversion Of Glycerol 3-Phosphate To Dihydroxyacetone. Uses Molecular Oxygen Or Nitrate As Electron Acceptor. [C]

COG id: COG0578

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI285002233, Length=534, Percent_Identity=37.4531835205993, Blast_Score=349, Evalue=3e-96,
Organism=Homo sapiens, GI285002231, Length=534, Percent_Identity=37.4531835205993, Blast_Score=349, Evalue=3e-96,
Organism=Escherichia coli, GI2367226, Length=472, Percent_Identity=30.0847457627119, Blast_Score=161, Evalue=1e-40,
Organism=Escherichia coli, GI1788574, Length=409, Percent_Identity=29.8288508557457, Blast_Score=110, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI115534726, Length=525, Percent_Identity=37.7142857142857, Blast_Score=332, Evalue=2e-91,
Organism=Caenorhabditis elegans, GI17509253, Length=535, Percent_Identity=37.0093457943925, Blast_Score=310, Evalue=1e-84,
Organism=Saccharomyces cerevisiae, GI6322036, Length=585, Percent_Identity=37.2649572649573, Blast_Score=322, Evalue=8e-89,
Organism=Drosophila melanogaster, GI161077125, Length=541, Percent_Identity=37.3382624768946, Blast_Score=328, Evalue=5e-90,
Organism=Drosophila melanogaster, GI24653942, Length=541, Percent_Identity=37.3382624768946, Blast_Score=328, Evalue=5e-90,
Organism=Drosophila melanogaster, GI24653944, Length=541, Percent_Identity=37.3382624768946, Blast_Score=328, Evalue=5e-90,
Organism=Drosophila melanogaster, GI20130025, Length=541, Percent_Identity=37.3382624768946, Blast_Score=328, Evalue=5e-90,
Organism=Drosophila melanogaster, GI24586295, Length=525, Percent_Identity=32, Blast_Score=266, Evalue=3e-71,
Organism=Drosophila melanogaster, GI19921278, Length=531, Percent_Identity=32.391713747646, Blast_Score=234, Evalue=8e-62,
Organism=Drosophila melanogaster, GI45550977, Length=383, Percent_Identity=30.0261096605744, Blast_Score=160, Evalue=2e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR000447 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.1.5.3 [H]

Molecular weight: Translated: 58470; Mature: 58470

Theoretical pI: Translated: 9.38; Mature: 9.38

Prosite motif: PS00978 FAD_G3PDH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRSEQLLKLQNTENWDVIIIGGGASGLGTAIDAASRGYKTILLEAVDFAKGTSSRSTKL
CCCHHHHHEECCCCCCEEEEECCCCCCCHHHHHHHCCCCEEEEEEHHHHHCCCCCCCCEE
VHGGVRYLAQGDVHLVREALKERGLLAQNANHLVKNQSFVIPNYHWLSGYFYTIGLKIYD
EECCHHHHCCCCHHHHHHHHHHCCCCCCCCHHHHCCCCEECCCCHHHCEEEEEEHHHHHH
LLSGGLSLGSSKYLSKKKTIEMLPNVEEDGLVNGVIYHDGQFDDSRLAVNLAQTAVENGA
HHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCHHEEEHHHHHHCCCC
CVLNYTKVINLIKDDKNQITGVQAVDQETGINYNIKGAVVINATGVFTNAIMKLNDKVYK
EEEEHHHHHHHHHCCCHHCCCCEEEHHHCCCCEEEEEEEEEEECHHHHHHHHHHHHHHHH
KYIVPSQGIHLVFDKSFLPGEHALMIPKTKDGRVLFAVPWHNHVVVGTTDTLIKKQSLEP
HHCCCCCCEEEEEECCCCCCCCEEEEECCCCCEEEEEECCCCEEEEECCHHHHHHCCCCC
IALESEIEFVLETAQRFLAKKPTRADVLSVFAGLRPLAAPKEEGRSTKEVSRSHKIIVSE
EEEHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCHHHCCCHHHHHHCCEEEEEC
TGLITITGGKWTTYRKIAEDIIDKAILKGKLPKKPCITQNLSIHGNKPTTTLDRENHLYI
CCEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCCCCEECCCCEEEE
YGSDITKILQLQEKEPELKEKLHLDYEFTLAEIVWAVRYEMARTVDDILARRVRLLFLDA
EECCHHHHHHHHCCCCCHHHHHCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEC
RAAIEVSEKTARVIAKELGHDENWVAKEIADFKATSKGFFLSEFR
HHHEEEHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCEEECCC
>Mature Secondary Structure
MNRSEQLLKLQNTENWDVIIIGGGASGLGTAIDAASRGYKTILLEAVDFAKGTSSRSTKL
CCCHHHHHEECCCCCCEEEEECCCCCCCHHHHHHHCCCCEEEEEEHHHHHCCCCCCCCEE
VHGGVRYLAQGDVHLVREALKERGLLAQNANHLVKNQSFVIPNYHWLSGYFYTIGLKIYD
EECCHHHHCCCCHHHHHHHHHHCCCCCCCCHHHHCCCCEECCCCHHHCEEEEEEHHHHHH
LLSGGLSLGSSKYLSKKKTIEMLPNVEEDGLVNGVIYHDGQFDDSRLAVNLAQTAVENGA
HHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCHHEEEHHHHHHCCCC
CVLNYTKVINLIKDDKNQITGVQAVDQETGINYNIKGAVVINATGVFTNAIMKLNDKVYK
EEEEHHHHHHHHHCCCHHCCCCEEEHHHCCCCEEEEEEEEEEECHHHHHHHHHHHHHHHH
KYIVPSQGIHLVFDKSFLPGEHALMIPKTKDGRVLFAVPWHNHVVVGTTDTLIKKQSLEP
HHCCCCCCEEEEEECCCCCCCCEEEEECCCCCEEEEEECCCCEEEEECCHHHHHHCCCCC
IALESEIEFVLETAQRFLAKKPTRADVLSVFAGLRPLAAPKEEGRSTKEVSRSHKIIVSE
EEEHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCHHHCCCHHHHHHCCEEEEEC
TGLITITGGKWTTYRKIAEDIIDKAILKGKLPKKPCITQNLSIHGNKPTTTLDRENHLYI
CCEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCCCCEECCCCEEEE
YGSDITKILQLQEKEPELKEKLHLDYEFTLAEIVWAVRYEMARTVDDILARRVRLLFLDA
EECCHHHHHHHHCCCCCHHHHHCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEC
RAAIEVSEKTARVIAKELGHDENWVAKEIADFKATSKGFFLSEFR
HHHEEEHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]