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The map label for this gene is ttgG [H]

Identifier: 146302590

GI number: 146302590

Start: 5886105

End: 5887187

Strand: Reverse

Name: ttgG [H]

Synonym: Fjoh_4863

Alternate gene names: 146302590

Gene position: 5887187-5886105 (Counterclockwise)

Preceding gene: 146302591

Following gene: 146302589

Centisome position: 96.56

GC content: 33.52

Gene sequence:

>1083_bases
ATGAAAAAAATCATTGTTTTCACAGGCTTAATGGCCTTGGTGTGCTTAACGAGCTGTACATCTAAAAAAGAAGAAAAAGA
AGAAGTTGAAAAATTTACCGTTACCAATCCGGTTAAAATCGATACTTCGTTTACAAAAGAATATGTTTCACAAATAAAAT
CAGTTCGAAATATCGAATTGCGTGCCCAGGAAAAAGGGTTTTTACAAAATATATACGTTGATGAAGGACAGTTTGTAAAA
AAAGGACAACTGTTGTTTAAAATTATGCCAAATATGTATGAGGCTGAACTACTTAAAGCACAGTCTGAACAAAAATCAGC
AGAAATCGAATTGCAGAACTCTAAATTACTGGCAGATAAAAATATCGTTTCTAAAAACGAATTGAGCGTTGCTCAGGCAA
AACTACAATCTGCAAAAGCAGAAGTATCATTAGCAAGACTTCATTTATCATTTACAGAAATCAGAGCTCCGTTTGACGGA
ACAATCGACCGTATTCCTTTAAAACTAGGAAGTTTAATCGACGAAGGCGAATTGCTGACAAGTCTTTCAGACAACAGCCA
GATGTTTGCTTACTTCAACGTTTCGGAGCCAGAATATCTTCAGTATGAAACCAATATTAAAGATCGTGCTGATAACAAAG
TGGCTTTAGTATTAGCAAACGGAGATATTTTTAAAGATAAAGGAAATGTTGAAGTTATAGAAAGTGAATTCAATAACGAA
ACAGGAAATATCGCTTTCAGAGCAAGATTCCCAAATTCTGGAAAATTACTTAGAAATGGCGAAACAGGACAGGTTCAAAT
GAATGTTCCTCTTAAAAATGCTATTGTAATTCCACAAAAAGCAACTTACGAAATTCAGGATAAAAAATATGTTTTTGTAG
TAGGCAAGGACGACAAAGTTAGTTCAAGAGAAATTACAATTACTGGTGAAATCCCTGATTTGTACGTGATTAAAAGCGGT
ATTTCAGAAAATGACAGAATCTTACTTGAAGGTGTTCAGAAAGTAAAAGAAAACGACAAAATTAAATATGATTACCAATC
GCCTAAAGAGGTAATGAATCATTTACGTTTAAAAGCAGAATAG

Upstream 100 bases:

>100_bases
TATCAAAGTTAAGGTCTGGACTAAGGCTGACTGATGCATTTTAACATCCAAAAGGAATTTTCATTCCAAAGCTTCAATCG
CTTAATTTCCAAACTAAATC

Downstream 100 bases:

>100_bases
GTTTACTGGGTTTTAATCATTAAAAAATACAAAAATGTTTAATAAATTTATTCAAAGACCTGTTCTGTCGATAGTAATAT
CGTTGATTATTGTCTTCTTA

Product: RND family efflux transporter MFP subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 360; Mature: 360

Protein sequence:

>360_residues
MKKIIVFTGLMALVCLTSCTSKKEEKEEVEKFTVTNPVKIDTSFTKEYVSQIKSVRNIELRAQEKGFLQNIYVDEGQFVK
KGQLLFKIMPNMYEAELLKAQSEQKSAEIELQNSKLLADKNIVSKNELSVAQAKLQSAKAEVSLARLHLSFTEIRAPFDG
TIDRIPLKLGSLIDEGELLTSLSDNSQMFAYFNVSEPEYLQYETNIKDRADNKVALVLANGDIFKDKGNVEVIESEFNNE
TGNIAFRARFPNSGKLLRNGETGQVQMNVPLKNAIVIPQKATYEIQDKKYVFVVGKDDKVSSREITITGEIPDLYVIKSG
ISENDRILLEGVQKVKENDKIKYDYQSPKEVMNHLRLKAE

Sequences:

>Translated_360_residues
MKKIIVFTGLMALVCLTSCTSKKEEKEEVEKFTVTNPVKIDTSFTKEYVSQIKSVRNIELRAQEKGFLQNIYVDEGQFVK
KGQLLFKIMPNMYEAELLKAQSEQKSAEIELQNSKLLADKNIVSKNELSVAQAKLQSAKAEVSLARLHLSFTEIRAPFDG
TIDRIPLKLGSLIDEGELLTSLSDNSQMFAYFNVSEPEYLQYETNIKDRADNKVALVLANGDIFKDKGNVEVIESEFNNE
TGNIAFRARFPNSGKLLRNGETGQVQMNVPLKNAIVIPQKATYEIQDKKYVFVVGKDDKVSSREITITGEIPDLYVIKSG
ISENDRILLEGVQKVKENDKIKYDYQSPKEVMNHLRLKAE
>Mature_360_residues
MKKIIVFTGLMALVCLTSCTSKKEEKEEVEKFTVTNPVKIDTSFTKEYVSQIKSVRNIELRAQEKGFLQNIYVDEGQFVK
KGQLLFKIMPNMYEAELLKAQSEQKSAEIELQNSKLLADKNIVSKNELSVAQAKLQSAKAEVSLARLHLSFTEIRAPFDG
TIDRIPLKLGSLIDEGELLTSLSDNSQMFAYFNVSEPEYLQYETNIKDRADNKVALVLANGDIFKDKGNVEVIESEFNNE
TGNIAFRARFPNSGKLLRNGETGQVQMNVPLKNAIVIPQKATYEIQDKKYVFVVGKDDKVSSREITITGEIPDLYVIKSG
ISENDRILLEGVQKVKENDKIKYDYQSPKEVMNHLRLKAE

Specific function: The periplasmic linker component of an organic solvent efflux pump. Involved in export of a number of organic solvents, including toluene and styrene. This is the most important solvent efflux pump in this strain, although it can export AMP and some antib

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1789665, Length=375, Percent_Identity=25.3333333333333, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1786668, Length=370, Percent_Identity=27.8378378378378, Blast_Score=107, Evalue=9e-25,
Organism=Escherichia coli, GI1789929, Length=367, Percent_Identity=24.2506811989101, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI87082036, Length=312, Percent_Identity=26.2820512820513, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI87081796, Length=316, Percent_Identity=24.3670886075949, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 40721; Mature: 40721

Theoretical pI: Translated: 6.04; Mature: 6.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKIIVFTGLMALVCLTSCTSKKEEKEEVEKFTVTNPVKIDTSFTKEYVSQIKSVRNIEL
CCEEEEHHHHHHHHHHHHHCCCHHHHHHHHHEECCCCEEECHHHHHHHHHHHHHHHCEEE
RAQEKGFLQNIYVDEGQFVKKGQLLFKIMPNMYEAELLKAQSEQKSAEIELQNSKLLADK
EECCCCCEEEEEECCCCEECCCCEEEECCCCHHHHHHHHHHCCCCCCEEEEECCEEEECC
NIVSKNELSVAQAKLQSAKAEVSLARLHLSFTEIRAPFDGTIDRIPLKLGSLIDEGELLT
CCCCCCHHHHHHHHHHHHHHHEEEEEEEEEHHHHCCCCCCCHHHCCHHHHCCCCCCHHEE
SLSDNSQMFAYFNVSEPEYLQYETNIKDRADNKVALVLANGDIFKDKGNVEVIESEFNNE
ECCCCCEEEEEEECCCCCEEEEECCCCCCCCCEEEEEEECCCEEECCCCEEEEEECCCCC
TGNIAFRARFPNSGKLLRNGETGQVQMNVPLKNAIVIPQKATYEIQDKKYVFVVGKDDKV
CCCEEEEEECCCCCCEEECCCCCEEEECCCCCCEEECCCCCEEEECCCEEEEEEECCCCC
SSREITITGEIPDLYVIKSGISENDRILLEGVQKVKENDKIKYDYQSPKEVMNHLRLKAE
CCEEEEEEECCCCEEEEECCCCCCCEEHHHHHHHHHCCCCEEECCCCHHHHHHHHCCCCC
>Mature Secondary Structure
MKKIIVFTGLMALVCLTSCTSKKEEKEEVEKFTVTNPVKIDTSFTKEYVSQIKSVRNIEL
CCEEEEHHHHHHHHHHHHHCCCHHHHHHHHHEECCCCEEECHHHHHHHHHHHHHHHCEEE
RAQEKGFLQNIYVDEGQFVKKGQLLFKIMPNMYEAELLKAQSEQKSAEIELQNSKLLADK
EECCCCCEEEEEECCCCEECCCCEEEECCCCHHHHHHHHHHCCCCCCEEEEECCEEEECC
NIVSKNELSVAQAKLQSAKAEVSLARLHLSFTEIRAPFDGTIDRIPLKLGSLIDEGELLT
CCCCCCHHHHHHHHHHHHHHHEEEEEEEEEHHHHCCCCCCCHHHCCHHHHCCCCCCHHEE
SLSDNSQMFAYFNVSEPEYLQYETNIKDRADNKVALVLANGDIFKDKGNVEVIESEFNNE
ECCCCCEEEEEEECCCCCEEEEECCCCCCCCCEEEEEEECCCEEECCCCEEEEEECCCCC
TGNIAFRARFPNSGKLLRNGETGQVQMNVPLKNAIVIPQKATYEIQDKKYVFVVGKDDKV
CCCEEEEEECCCCCCEEECCCCCEEEECCCCCCEEECCCCCEEEECCCEEEEEEECCCCC
SSREITITGEIPDLYVIKSGISENDRILLEGVQKVKENDKIKYDYQSPKEVMNHLRLKAE
CCEEEEEEECCCCEEEEECCCCCCCEEHHHHHHHHHCCCCEEECCCCHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11395460 [H]