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The map label for this gene is ilvE [H]

Identifier: 146302497

GI number: 146302497

Start: 5765536

End: 5766606

Strand: Direct

Name: ilvE [H]

Synonym: Fjoh_4770

Alternate gene names: 146302497

Gene position: 5765536-5766606 (Clockwise)

Preceding gene: 146302494

Following gene: 146302501

Centisome position: 94.57

GC content: 35.57

Gene sequence:

>1071_bases
ATGAGTACAACTCAAACAAGCAAAATTGAAATCAGAAAAGCTGAATCGTCTAAGATAAGCTCTGTAGACTTTGAAAACTT
AAGCTTTGGTGCTGTATTTACAGACCATTTATTTGAATGTGATTACAAAAACGGACAATGGCAGACTCCGGTCATTAAGC
CTTATGCTCCTATTTTAATGGATCCTTCTTCTAAAGTCTTTCATTATGGTCAAGCAATTTTTGAGGGAATGAAAGCTTAT
AAAGATGAAAATAATGATGTTTGGTTGTTTAGACCTGATGAAAACTACAAACGTTTTAACAATTCTGCTGTTCGTATGGC
AATGCCAGAAGTTCCGGAAGATATTTTCATGGACGGTTTAAATGAATTATTAAAAATTGACCAAGAATGGATTCAGAGAG
GAAACGGAGCAAGTATGTATATCCGTCCTTTTATGATTGCTACAGGACCTGGAGTAATTGCTAATCCTTCTGACGAATAT
AAGTTCATGATTTTACTTTCTCCTGCAAAAGCATATTACGGAGGCGAAGTAAAAGTTATTATTGCTGAGCATTACAGCCG
CGCTGCAAATGGCGGAATTGGTGCTGCAAAAGCTGCAGGAAACTATGCTGCACAGTTTTACCCAACTAATTTAGCAAACA
AAGATGGTTTCCAGCAAGTTATCTGGACTGACGATGCAACTCATACAAAGTTAGAAGAAGCTGGAACAATGAATGTTTTC
TTCAGAATTAACGATACTTTATTAACTGCGCCGACAAGCGAAAGAATTTTAGATGGTGTTACCAGAAAAAGTTTAATTGC
TATGGCAGAAAAAGAAGGATTAAATGTTGAAGTTCGCCCTGTAATTGTTTCAGAATTAGTAGAAGCTGCTAAAAACGGAT
CTTTAAAAGAAATTTTCGGAGCTGGTACTGCCGCTGTTATCAGCGTTATTAAAGGCTTCTCATACAAAGATGAGTATTTT
GAATTAACTCCAATCGAGAATTCATATGCTTCATTCTTAAAAGAAAAATTAACAAGTCTTCAAAACAAACTTTCTGAAGA
TACTTACGGATGGACAGTTAAAGTTCAATAA

Upstream 100 bases:

>100_bases
TTTCCGTAATTTTGCATTCAGTAAAACCTATTCTTCATCAGATCATTACGTTAGATTTTCATCTGAAAGAATACAAAATA
GATAAAAACTTTACATAATT

Downstream 100 bases:

>100_bases
TCCATAATTAGTTTAAAATATAAACCCGACAGATTTTAAAAAATTTGTCGGGTTTATTTTTCTTTATAATTATCATATTC
CCAATCAAAATATTTTTTAA

Product: branched-chain amino acid aminotransferase

Products: NA

Alternate protein names: BCAT [H]

Number of amino acids: Translated: 356; Mature: 355

Protein sequence:

>356_residues
MSTTQTSKIEIRKAESSKISSVDFENLSFGAVFTDHLFECDYKNGQWQTPVIKPYAPILMDPSSKVFHYGQAIFEGMKAY
KDENNDVWLFRPDENYKRFNNSAVRMAMPEVPEDIFMDGLNELLKIDQEWIQRGNGASMYIRPFMIATGPGVIANPSDEY
KFMILLSPAKAYYGGEVKVIIAEHYSRAANGGIGAAKAAGNYAAQFYPTNLANKDGFQQVIWTDDATHTKLEEAGTMNVF
FRINDTLLTAPTSERILDGVTRKSLIAMAEKEGLNVEVRPVIVSELVEAAKNGSLKEIFGAGTAAVISVIKGFSYKDEYF
ELTPIENSYASFLKEKLTSLQNKLSEDTYGWTVKVQ

Sequences:

>Translated_356_residues
MSTTQTSKIEIRKAESSKISSVDFENLSFGAVFTDHLFECDYKNGQWQTPVIKPYAPILMDPSSKVFHYGQAIFEGMKAY
KDENNDVWLFRPDENYKRFNNSAVRMAMPEVPEDIFMDGLNELLKIDQEWIQRGNGASMYIRPFMIATGPGVIANPSDEY
KFMILLSPAKAYYGGEVKVIIAEHYSRAANGGIGAAKAAGNYAAQFYPTNLANKDGFQQVIWTDDATHTKLEEAGTMNVF
FRINDTLLTAPTSERILDGVTRKSLIAMAEKEGLNVEVRPVIVSELVEAAKNGSLKEIFGAGTAAVISVIKGFSYKDEYF
ELTPIENSYASFLKEKLTSLQNKLSEDTYGWTVKVQ
>Mature_355_residues
STTQTSKIEIRKAESSKISSVDFENLSFGAVFTDHLFECDYKNGQWQTPVIKPYAPILMDPSSKVFHYGQAIFEGMKAYK
DENNDVWLFRPDENYKRFNNSAVRMAMPEVPEDIFMDGLNELLKIDQEWIQRGNGASMYIRPFMIATGPGVIANPSDEYK
FMILLSPAKAYYGGEVKVIIAEHYSRAANGGIGAAKAAGNYAAQFYPTNLANKDGFQQVIWTDDATHTKLEEAGTMNVFF
RINDTLLTAPTSERILDGVTRKSLIAMAEKEGLNVEVRPVIVSELVEAAKNGSLKEIFGAGTAAVISVIKGFSYKDEYFE
LTPIENSYASFLKEKLTSLQNKLSEDTYGWTVKVQ

Specific function: Acts on leucine, isoleucine and valine [H]

COG id: COG0115

COG function: function code EH; Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI296010904, Length=344, Percent_Identity=34.0116279069767, Blast_Score=197, Evalue=9e-51,
Organism=Homo sapiens, GI38176287, Length=344, Percent_Identity=34.0116279069767, Blast_Score=197, Evalue=9e-51,
Organism=Homo sapiens, GI296010906, Length=344, Percent_Identity=34.0116279069767, Blast_Score=197, Evalue=9e-51,
Organism=Homo sapiens, GI50658084, Length=337, Percent_Identity=32.9376854599407, Blast_Score=196, Evalue=3e-50,
Organism=Homo sapiens, GI258614015, Length=289, Percent_Identity=32.8719723183391, Blast_Score=159, Evalue=4e-39,
Organism=Homo sapiens, GI296010900, Length=344, Percent_Identity=30.2325581395349, Blast_Score=151, Evalue=1e-36,
Organism=Homo sapiens, GI296010902, Length=344, Percent_Identity=30.2325581395349, Blast_Score=151, Evalue=1e-36,
Organism=Escherichia coli, GI48994963, Length=301, Percent_Identity=26.9102990033223, Blast_Score=95, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI17568601, Length=330, Percent_Identity=33.6363636363636, Blast_Score=186, Evalue=2e-47,
Organism=Caenorhabditis elegans, GI17565728, Length=360, Percent_Identity=30.5555555555556, Blast_Score=149, Evalue=2e-36,
Organism=Saccharomyces cerevisiae, GI6322002, Length=322, Percent_Identity=37.2670807453416, Blast_Score=203, Evalue=4e-53,
Organism=Saccharomyces cerevisiae, GI6322608, Length=330, Percent_Identity=35.7575757575758, Blast_Score=200, Evalue=4e-52,
Organism=Drosophila melanogaster, GI24641779, Length=353, Percent_Identity=35.9773371104816, Blast_Score=209, Evalue=2e-54,

Paralogues:

None

Copy number: 2342 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 11,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001544
- InterPro:   IPR018300
- InterPro:   IPR005786 [H]

Pfam domain/function: PF01063 Aminotran_4 [H]

EC number: =2.6.1.42 [H]

Molecular weight: Translated: 39776; Mature: 39645

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: PS00770 AA_TRANSFER_CLASS_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTTQTSKIEIRKAESSKISSVDFENLSFGAVFTDHLFECDYKNGQWQTPVIKPYAPILM
CCCCCCCEEEEEECCCCCCCCCCCCCCEECHHHHHHHEECCCCCCCCCCCCCCCCCCEEE
DPSSKVFHYGQAIFEGMKAYKDENNDVWLFRPDENYKRFNNSAVRMAMPEVPEDIFMDGL
CCCHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHCCCEEEEECCCCCHHHHHHHH
NELLKIDQEWIQRGNGASMYIRPFMIATGPGVIANPSDEYKFMILLSPAKAYYGGEVKVI
HHHHHHHHHHHHCCCCCEEEEEEEEEEECCCEECCCCCCEEEEEEEECCHHHCCCCEEEE
IAEHYSRAANGGIGAAKAAGNYAAQFYPTNLANKDGFQQVIWTDDATHTKLEEAGTMNVF
EEEHHHHHCCCCCCCHHCCCCCEEEEECCCCCCCCCCEEEEECCCCCHHHHHHCCCEEEE
FRINDTLLTAPTSERILDGVTRKSLIAMAEKEGLNVEVRPVIVSELVEAAKNGSLKEIFG
EEECCEEEECCCHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHCCCHHHHHC
AGTAAVISVIKGFSYKDEYFELTPIENSYASFLKEKLTSLQNKLSEDTYGWTVKVQ
CCHHHHHHHHHCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEC
>Mature Secondary Structure 
STTQTSKIEIRKAESSKISSVDFENLSFGAVFTDHLFECDYKNGQWQTPVIKPYAPILM
CCCCCCEEEEEECCCCCCCCCCCCCCEECHHHHHHHEECCCCCCCCCCCCCCCCCCEEE
DPSSKVFHYGQAIFEGMKAYKDENNDVWLFRPDENYKRFNNSAVRMAMPEVPEDIFMDGL
CCCHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHCCCEEEEECCCCCHHHHHHHH
NELLKIDQEWIQRGNGASMYIRPFMIATGPGVIANPSDEYKFMILLSPAKAYYGGEVKVI
HHHHHHHHHHHHCCCCCEEEEEEEEEEECCCEECCCCCCEEEEEEEECCHHHCCCCEEEE
IAEHYSRAANGGIGAAKAAGNYAAQFYPTNLANKDGFQQVIWTDDATHTKLEEAGTMNVF
EEEHHHHHCCCCCCCHHCCCCCEEEEECCCCCCCCCCEEEEECCCCCHHHHHHCCCEEEE
FRINDTLLTAPTSERILDGVTRKSLIAMAEKEGLNVEVRPVIVSELVEAAKNGSLKEIFG
EEECCEEEECCCHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHCCCHHHHHC
AGTAAVISVIKGFSYKDEYFELTPIENSYASFLKEKLTSLQNKLSEDTYGWTVKVQ
CCHHHHHHHHHCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA