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The map label for this gene is oxyR [H]

Identifier: 146302494

GI number: 146302494

Start: 5763218

End: 5764159

Strand: Direct

Name: oxyR [H]

Synonym: Fjoh_4767

Alternate gene names: 146302494

Gene position: 5763218-5764159 (Clockwise)

Preceding gene: 146302489

Following gene: 146302497

Centisome position: 94.53

GC content: 33.55

Gene sequence:

>942_bases
ATGACGATAACTCAATTACAATATGTATTAGCTGTTGCAGAGCATAAAAACTTTACACTTGCCGCCGAAAAGTGTTTCGT
AACACAGCCAACATTAAGTATGCAGATTCAAAAAATTGAAGAAGAACTTAATATTTTAATTTTCGACAGAAGCAAAAAAC
CAATTCAGCTTACAGACATTGGACAAAAAATTGTAAATCAGGCTAAAAATATTGTAAACGAAGCTGACCGAATCAAAGAT
ATTGTAGAACAGCAGAAAGGTTTTATTGGCGGAGAATTTCGATTAGGAATTATACCTACTATTATGCCAACCCTTTTACC
AATGTTTTTAAATAATTTTATTAAAAAATATCCAAAAGTTAAGCTTTTAATTGAAGAGCTTAATACAGATGAAATTATAG
TAAAATTAAAAAACGGTCATCTGGACGCTGCCATTGCCGCCACGCCTCTTGAAGATGAAAAGATAAAAGAAATTGTTTTG
TATTTTGAGCCTTTTGTGGCTTATATTCCGGAACATCATCATAGTTTTCAAAAAGAAGAAATTGAAGTTGCCGATTTAAA
CATTAATGAAATCCTGCTTTTACAAGACGGACATTGTTTTAGAGACGGAATTTTAAATTTATGCAAAAACGGCACTGATG
TCGACCAAAACAATTTTCAGATTCAAAGCGGCAGTTTTGAAACTTTAATAAAATTAGCCGATGAAGGTTTGGGCACAACG
TTACTTCCGTACTTGCACACCTTAGACTTAAAAGAATCCGATAAACTAAAACTACGAAACTTTAAAGAACCAAAACCTGC
CCGAGAGGTAAGTTTAATTTACCCAAAGAGCGAATTAAAAATGCAGATCATTGATGCCATTCGATCTACAATTGCCGGTG
TTGTAAAAGGCGCTATTGTTTTTCAAAATGTGCAGATCATCAGCCCGCTGCAAAAAAAGTAA

Upstream 100 bases:

>100_bases
TTTTAATAACTAAGTTACTACAAATTTAAAGCAACTTGATTAAAAAAATTATAAAAAAAAATTATATTTACCTATTTTTG
CATCAAAAATTACTATCAAA

Downstream 100 bases:

>100_bases
TCATAAAAAAAGGAGCCAGTTTGGCTCCTTTTTCTTTTATACTTTAATTAGCTGTAGACTTGGTTTTAATTCTGGTTTTT
CGATTACAAAACTTAATAAC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Morphology and auto-aggregation control protein [H]

Number of amino acids: Translated: 313; Mature: 312

Protein sequence:

>313_residues
MTITQLQYVLAVAEHKNFTLAAEKCFVTQPTLSMQIQKIEEELNILIFDRSKKPIQLTDIGQKIVNQAKNIVNEADRIKD
IVEQQKGFIGGEFRLGIIPTIMPTLLPMFLNNFIKKYPKVKLLIEELNTDEIIVKLKNGHLDAAIAATPLEDEKIKEIVL
YFEPFVAYIPEHHHSFQKEEIEVADLNINEILLLQDGHCFRDGILNLCKNGTDVDQNNFQIQSGSFETLIKLADEGLGTT
LLPYLHTLDLKESDKLKLRNFKEPKPAREVSLIYPKSELKMQIIDAIRSTIAGVVKGAIVFQNVQIISPLQKK

Sequences:

>Translated_313_residues
MTITQLQYVLAVAEHKNFTLAAEKCFVTQPTLSMQIQKIEEELNILIFDRSKKPIQLTDIGQKIVNQAKNIVNEADRIKD
IVEQQKGFIGGEFRLGIIPTIMPTLLPMFLNNFIKKYPKVKLLIEELNTDEIIVKLKNGHLDAAIAATPLEDEKIKEIVL
YFEPFVAYIPEHHHSFQKEEIEVADLNINEILLLQDGHCFRDGILNLCKNGTDVDQNNFQIQSGSFETLIKLADEGLGTT
LLPYLHTLDLKESDKLKLRNFKEPKPAREVSLIYPKSELKMQIIDAIRSTIAGVVKGAIVFQNVQIISPLQKK
>Mature_312_residues
TITQLQYVLAVAEHKNFTLAAEKCFVTQPTLSMQIQKIEEELNILIFDRSKKPIQLTDIGQKIVNQAKNIVNEADRIKDI
VEQQKGFIGGEFRLGIIPTIMPTLLPMFLNNFIKKYPKVKLLIEELNTDEIIVKLKNGHLDAAIAATPLEDEKIKEIVLY
FEPFVAYIPEHHHSFQKEEIEVADLNINEILLLQDGHCFRDGILNLCKNGTDVDQNNFQIQSGSFETLIKLADEGLGTTL
LPYLHTLDLKESDKLKLRNFKEPKPAREVSLIYPKSELKMQIIDAIRSTIAGVVKGAIVFQNVQIISPLQKK

Specific function: Hydrogen peroxide sensor. Activates the expression of a regulon of hydrogen peroxide-inducible genes such as katG, gor, ahpC, ahpF, oxyS (a regulatory RNA), dps, fur and grxA. OxyR expression is negatively autoregulated by binding to a 43 bp region upstre

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790399, Length=298, Percent_Identity=34.5637583892617, Blast_Score=192, Evalue=2e-50,
Organism=Escherichia coli, GI157672245, Length=243, Percent_Identity=28.8065843621399, Blast_Score=115, Evalue=5e-27,
Organism=Escherichia coli, GI1787879, Length=301, Percent_Identity=26.2458471760797, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1788887, Length=295, Percent_Identity=25.7627118644068, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1787530, Length=153, Percent_Identity=31.3725490196078, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI145693105, Length=184, Percent_Identity=25.5434782608696, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI1787601, Length=143, Percent_Identity=30.0699300699301, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI2367136, Length=180, Percent_Identity=27.7777777777778, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI1788748, Length=283, Percent_Identity=23.321554770318, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1787806, Length=173, Percent_Identity=24.8554913294798, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1790208, Length=149, Percent_Identity=27.5167785234899, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788706, Length=217, Percent_Identity=25.3456221198157, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI145693193, Length=153, Percent_Identity=25.4901960784314, Blast_Score=61, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 35556; Mature: 35425

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTITQLQYVLAVAEHKNFTLAAEKCFVTQPTLSMQIQKIEEELNILIFDRSKKPIQLTDI
CCHHHHHHHHHHHHCCCEEEEECEEEEECCHHHHHHHHHHHHCCEEEEECCCCCEEHHHH
GQKIVNQAKNIVNEADRIKDIVEQQKGFIGGEFRLGIIPTIMPTLLPMFLNNFIKKYPKV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHCCHH
KLLIEELNTDEIIVKLKNGHLDAAIAATPLEDEKIKEIVLYFEPFVAYIPEHHHSFQKEE
EEHHHHCCCCEEEEEEECCCCCEEEEECCCCHHHHHHHHHHHHHHHHHCCHHHCCCCCCC
IEVADLNINEILLLQDGHCFRDGILNLCKNGTDVDQNNFQIQSGSFETLIKLADEGLGTT
EEEEECCCCEEEEEECCCHHHHHHHHHHCCCCCCCCCCEEEECCCHHHHHHHHHCCCCCH
LLPYLHTLDLKESDKLKLRNFKEPKPAREVSLIYPKSELKMQIIDAIRSTIAGVVKGAIV
HHHHHHHCCCCCCCCHHHCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHH
FQNVQIISPLQKK
EECHHHHCCCCCC
>Mature Secondary Structure 
TITQLQYVLAVAEHKNFTLAAEKCFVTQPTLSMQIQKIEEELNILIFDRSKKPIQLTDI
CHHHHHHHHHHHHCCCEEEEECEEEEECCHHHHHHHHHHHHCCEEEEECCCCCEEHHHH
GQKIVNQAKNIVNEADRIKDIVEQQKGFIGGEFRLGIIPTIMPTLLPMFLNNFIKKYPKV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHCCHH
KLLIEELNTDEIIVKLKNGHLDAAIAATPLEDEKIKEIVLYFEPFVAYIPEHHHSFQKEE
EEHHHHCCCCEEEEEEECCCCCEEEEECCCCHHHHHHHHHHHHHHHHHCCHHHCCCCCCC
IEVADLNINEILLLQDGHCFRDGILNLCKNGTDVDQNNFQIQSGSFETLIKLADEGLGTT
EEEEECCCCEEEEEECCCHHHHHHHHHHCCCCCCCCCCEEEECCCHHHHHHHHHCCCCCH
LLPYLHTLDLKESDKLKLRNFKEPKPAREVSLIYPKSELKMQIIDAIRSTIAGVVKGAIV
HHHHHHHCCCCCCCCHHHCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHH
FQNVQIISPLQKK
EECHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]