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The map label for this gene is can [H]

Identifier: 146302490

GI number: 146302490

Start: 5759723

End: 5760358

Strand: Reverse

Name: can [H]

Synonym: Fjoh_4763

Alternate gene names: 146302490

Gene position: 5760358-5759723 (Counterclockwise)

Preceding gene: 146302491

Following gene: 146302487

Centisome position: 94.48

GC content: 36.01

Gene sequence:

>636_bases
ATGAGAAAGTTTTATGAACAAATACTAGAGAACAATAAAAAATGGGTTGAAGATTCTTTAGCAAAAGACCCGAATTACTT
TGCTGATTTAGCTAAAGGACAATCACCGCCTTTATTATGGATTGGATGTTCTGACAGCCGTGTTCCTGCAAATGAAATTA
TTGGAGCAAAACCAGGTGAAGTTTTTGTTCACAGAAACATTGCTAACATGGTAGTTCACTCAGACATGAATATGTTAAGT
GTACTGGATTATGCTGTAAACGTTTTAAAAGTAAAACACGTTATTGTATGCGGACATTACGGATGCGGTGGTGTAAAAGC
AGCAATGGGACAGCAGTCTGTTGGAATTATCGACAACTGGCTTCGTCATATTAAAGATGAATACCGTCTGCATGACAAAT
ATTTAAATTCAATTACTGACGAAACTGAGCGTTTTAATGCTTTTGTTGAAATCAATGCAAAAGAGCAGGTTTACAATTTA
GCTAAAACTTCGATTGTGCAGGGAGCTTGGAAAAGCGGTCAGGATTTAATGCTTCACGGATGGGTTTACGGATTAAATTC
TGGTTTTGTAACCGATTTAAATGTTACCATTAGTTCAAATGAAGAACTAGATCAGGTTTATCAGCTTGATCTTTAA

Upstream 100 bases:

>100_bases
ATCAGGTTTGAGAACTATCAAAATTTAAATAACTTTACGGAAATTAAAGGTGTTTTTGATATGCTTAAGCATTGATAATT
CCAAAAAAACAAAAAAAAGG

Downstream 100 bases:

>100_bases
TATAAAAAGAAAATCGCCTCAAAAGGGCGATTTTTTTTATTCGTTTTCGTCTAGATTTTCATTAAATGCAGATGGTAACA
TGGTTGGTATAAACTTAATT

Product: carbonate dehydratase

Products: NA

Alternate protein names: Carbonate dehydratase 2 [H]

Number of amino acids: Translated: 211; Mature: 211

Protein sequence:

>211_residues
MRKFYEQILENNKKWVEDSLAKDPNYFADLAKGQSPPLLWIGCSDSRVPANEIIGAKPGEVFVHRNIANMVVHSDMNMLS
VLDYAVNVLKVKHVIVCGHYGCGGVKAAMGQQSVGIIDNWLRHIKDEYRLHDKYLNSITDETERFNAFVEINAKEQVYNL
AKTSIVQGAWKSGQDLMLHGWVYGLNSGFVTDLNVTISSNEELDQVYQLDL

Sequences:

>Translated_211_residues
MRKFYEQILENNKKWVEDSLAKDPNYFADLAKGQSPPLLWIGCSDSRVPANEIIGAKPGEVFVHRNIANMVVHSDMNMLS
VLDYAVNVLKVKHVIVCGHYGCGGVKAAMGQQSVGIIDNWLRHIKDEYRLHDKYLNSITDETERFNAFVEINAKEQVYNL
AKTSIVQGAWKSGQDLMLHGWVYGLNSGFVTDLNVTISSNEELDQVYQLDL
>Mature_211_residues
MRKFYEQILENNKKWVEDSLAKDPNYFADLAKGQSPPLLWIGCSDSRVPANEIIGAKPGEVFVHRNIANMVVHSDMNMLS
VLDYAVNVLKVKHVIVCGHYGCGGVKAAMGQQSVGIIDNWLRHIKDEYRLHDKYLNSITDETERFNAFVEINAKEQVYNL
AKTSIVQGAWKSGQDLMLHGWVYGLNSGFVTDLNVTISSNEELDQVYQLDL

Specific function: Unknown

COG id: COG0288

COG function: function code P; Carbonic anhydrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-class carbonic anhydrase family [H]

Homologues:

Organism=Escherichia coli, GI1786318, Length=206, Percent_Identity=49.0291262135922, Blast_Score=231, Evalue=3e-62,
Organism=Escherichia coli, GI1786534, Length=200, Percent_Identity=30, Blast_Score=94, Evalue=6e-21,
Organism=Saccharomyces cerevisiae, GI6324292, Length=193, Percent_Identity=33.160621761658, Blast_Score=107, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001765
- InterPro:   IPR015892 [H]

Pfam domain/function: PF00484 Pro_CA [H]

EC number: =4.2.1.1 [H]

Molecular weight: Translated: 23834; Mature: 23834

Theoretical pI: Translated: 5.87; Mature: 5.87

Prosite motif: PS00704 PROK_CO2_ANHYDRASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKFYEQILENNKKWVEDSLAKDPNYFADLAKGQSPPLLWIGCSDSRVPANEIIGAKPGE
CHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHCCCCCCEEEEECCCCCCCHHHHCCCCCCC
VFVHRNIANMVVHSDMNMLSVLDYAVNVLKVKHVIVCGHYGCGGVKAAMGQQSVGIIDNW
EEEECCHHHHHHHCCCHHHHHHHHHHHHHHHEEEEEECCCCCCCHHHHCCCCCCCHHHHH
LRHIKDEYRLHDKYLNSITDETERFNAFVEINAKEQVYNLAKTSIVQGAWKSGQDLMLHG
HHHHHHHHHHHHHHHHHHHCHHHHCEEEEEECCHHHHHHHHHHHHHHHHCCCCCCEEEEE
WVYGLNSGFVTDLNVTISSNEELDQVYQLDL
EEEECCCCEEEEEEEEECCCCHHHHHHHCCC
>Mature Secondary Structure
MRKFYEQILENNKKWVEDSLAKDPNYFADLAKGQSPPLLWIGCSDSRVPANEIIGAKPGE
CHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHCCCCCCEEEEECCCCCCCHHHHCCCCCCC
VFVHRNIANMVVHSDMNMLSVLDYAVNVLKVKHVIVCGHYGCGGVKAAMGQQSVGIIDNW
EEEECCHHHHHHHCCCHHHHHHHHHHHHHHHEEEEEECCCCCCCHHHHCCCCCCCHHHHH
LRHIKDEYRLHDKYLNSITDETERFNAFVEINAKEQVYNLAKTSIVQGAWKSGQDLMLHG
HHHHHHHHHHHHHHHHHHHCHHHHCEEEEEECCHHHHHHHHHHHHHHHHCCCCCCEEEEE
WVYGLNSGFVTDLNVTISSNEELDQVYQLDL
EEEECCCCEEEEEEEEECCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8202364; 9278503; 10493123 [H]