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The map label for this gene is fadN [H]

Identifier: 146302480

GI number: 146302480

Start: 5748664

End: 5751054

Strand: Direct

Name: fadN [H]

Synonym: Fjoh_4753

Alternate gene names: 146302480

Gene position: 5748664-5751054 (Clockwise)

Preceding gene: 146302479

Following gene: 146302481

Centisome position: 94.29

GC content: 36.68

Gene sequence:

>2391_bases
ATGAAACGCACAATTAAAAAAGTTGCTGTAATTGGATCCGGAATTATGGGTTCAGGTATAGCTTGTCATTTTGCTAACAT
TGGTGTCGAAGTTTTACTTCTTGACATTGTACCGCGTGAATTGACCGAAGCTGAAGCTAAAAAAGGGTTAACACTTGAAA
GTAAAGCCGTTCGTAACCGTGTGGTAAACGAACATTTGGCGAATTCATTAAAATCAAAACCATCTCCTATTTACAGTCAG
AAATTCGCAAATAGAATCACGACTGGAAATACAACAGATGATATGGCAAAAATTGCCAATGTTGACTGGATTATCGAGGT
TGTTGTAGAGCGTTTAGACATTAAGAAATTAGTTTTTGAACAAATCGAGAAATTCCGTAAACCCGGAACTTTGGTTACTT
CAAACACTTCTGGTATTCCAATTCATTTTATGAGTGAAGGAAGAAGCGAAGATTTCCAACAGCACTTCTGCGGAACCCAC
TTTTTTAACCCTGCGCGTTACTTAAAATTATTTGAAATTATTCCTGGTCCAAAAACTTCAACTGAAGTATTGGATTTCTT
AAACGAATACGGATCTAAATTCTTAGGAAAAACTTCGGTTGTTGCTAAAGATACTCCTGCGTTTATTGGAAACAGAATTG
GGATTTACGGAATCCAAAGTTTATTCCATTTAGTTAAAGAAATGGGATTAACGATTGAAGAAGTTGATAAATTGACTGGA
CCAGTAATTGGCCGTCCAAAATCGGCTACTTTCCGTACAGTTGACGTTGTTGGTTTAGATACTTTGGTACACGTTGCCAA
TGGTATTTACGAAAACTGCCCGAACGACGAACAACACGAATTGTTCAAACTTCCTGATTTCATCAACAAAATGATGGAAA
ATAATTGGTTAGGGAGCAAAACTGGACAAGGTTTTTATAAAAAAGTAGATAAAGATATTCTTTCTTTAGACTTAAATACA
TTAGAATACCGCGCTGCGAAAAAAGCAAATTTTGCTACTCTTGAACTAACAAAAACTATCGATAAACCTATCAATCGTTT
TAAAGTTTTAGTGAAAGGAACAGACAAAGCGGGAGAATTCTATCGTAAGAGTTTCGCCGGAATGTTTGCTTATGTGTCAA
ACAGAGTTCCAGAAATCTCAGACGAATTATACAAAATTGACGATGCCATGAAAGCTGGTTTTGGATGGGAAAATGGTCCA
TTCGAAATCTGGGATGCAATTGGTGTTGCCAAAGGAATTGAAATCATGAAAGCTGAAGGTTTAGAGCCTGCTGCATGGGT
TACTGAAATGCTGGCTTCTGGAAGCGATAGTTTCTATACTGTAAAAGAAGGAGCAACTTATTTCTATAACATTCCAACAA
AATCTCAAGTAAAAGTTCCTGGACAAGATTCATTTATTATCCTAAACAACATTCGCGAAAGCAAAAAAGTTTGGAGCAAC
AGTGGTGCAATCATTCAGGATTTAGGAGACGGAATCTTGAACTTAGAATTCCAATCTAAAATGAATACAATTGGTGGCGA
TGTACTTACTGCTATCAATAAAGCAATCGACTTATCTGAAAAAGAATATCAAGGCTTAGTTATTGGAAACCAAGCAGCTA
ATTTCTCAGTTGGAGCTAATATCGGAATGATTTTCATGATGGCAGTTGAGCAGGAATACGACGAATTAAACATGGCAATT
AAATTGTTCCAAGATACCATGATGCGTGTTCGTTACTCTTCTATTCCAGTTGTAGTGGCACCTCACGGAATGACTTTTGG
TGGTGGTTGCGAAATGAGCTTACACGCTGATAAAGTGGTTGCTGCTGCAGAAACTTACATGGGATTAGTTGAATTTGGTG
TTGGAGTTATCCCTGGTGGTGGTGGATCTAAAGAAATGACTTTAAGAGCATCTGATTTATTCCGCAAAAACGATGTGGAA
TTGAATGTTCTTCAAGAGTATTTCTTAACAATCGCAATGGCTAAAGTTTCGACTTCTGGTTATGAAGCTTTTGATACTGG
ACTTCTTCAACATGGAAAAGATGTTATTGTAGTAAACAAAGATCGTCAGATTGCAGAAGCTAAGAAACATGCTTTATTAT
TAGCAGAAGCCGGTTATACACAGCCTATCAGAAGAAACGATATTAAAGTTCTAGGAAAACAAGCTTTAGGTATGTTCTTA
GTGGGAACAGATCAAATGCAGGCTGGAAAATACATTTCTGAGCACGACAAGAAAATCGCTAACAAACTGGCTTATGTAAT
GGCTGGTGGTGATTTATCTGAAGCAACTTTAGTATCTGAACAATATTTATTAGATATCGAACGTGAAGCTTTCTTGAGTT
TATGTACAGAACGTAAGACTTTAGAAAGAATTCAATACATGTTGACTAAAGGAAAACCGCTTAGAAATTAG

Upstream 100 bases:

>100_bases
ATCATCAATGAACTGATTCACGATAAAAACATTTTTAATCAAATAGAAAACACAGAAAAAGAATAATATTCTTTTCCTCC
TACAAACAAATAATAACAAT

Downstream 100 bases:

>100_bases
TATTTGAGTATTAAGATCTGAGTATTAAGTATTAAGATTAAAAAGAATTATGCATCAATTTGAAAAGTTGAAAATCTGGC
AGAAAGCTATGGATATAACT

Product: 3-hydroxyacyl-CoA dehydrogenase, NAD-binding

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 796; Mature: 796

Protein sequence:

>796_residues
MKRTIKKVAVIGSGIMGSGIACHFANIGVEVLLLDIVPRELTEAEAKKGLTLESKAVRNRVVNEHLANSLKSKPSPIYSQ
KFANRITTGNTTDDMAKIANVDWIIEVVVERLDIKKLVFEQIEKFRKPGTLVTSNTSGIPIHFMSEGRSEDFQQHFCGTH
FFNPARYLKLFEIIPGPKTSTEVLDFLNEYGSKFLGKTSVVAKDTPAFIGNRIGIYGIQSLFHLVKEMGLTIEEVDKLTG
PVIGRPKSATFRTVDVVGLDTLVHVANGIYENCPNDEQHELFKLPDFINKMMENNWLGSKTGQGFYKKVDKDILSLDLNT
LEYRAAKKANFATLELTKTIDKPINRFKVLVKGTDKAGEFYRKSFAGMFAYVSNRVPEISDELYKIDDAMKAGFGWENGP
FEIWDAIGVAKGIEIMKAEGLEPAAWVTEMLASGSDSFYTVKEGATYFYNIPTKSQVKVPGQDSFIILNNIRESKKVWSN
SGAIIQDLGDGILNLEFQSKMNTIGGDVLTAINKAIDLSEKEYQGLVIGNQAANFSVGANIGMIFMMAVEQEYDELNMAI
KLFQDTMMRVRYSSIPVVVAPHGMTFGGGCEMSLHADKVVAAAETYMGLVEFGVGVIPGGGGSKEMTLRASDLFRKNDVE
LNVLQEYFLTIAMAKVSTSGYEAFDTGLLQHGKDVIVVNKDRQIAEAKKHALLLAEAGYTQPIRRNDIKVLGKQALGMFL
VGTDQMQAGKYISEHDKKIANKLAYVMAGGDLSEATLVSEQYLLDIEREAFLSLCTERKTLERIQYMLTKGKPLRN

Sequences:

>Translated_796_residues
MKRTIKKVAVIGSGIMGSGIACHFANIGVEVLLLDIVPRELTEAEAKKGLTLESKAVRNRVVNEHLANSLKSKPSPIYSQ
KFANRITTGNTTDDMAKIANVDWIIEVVVERLDIKKLVFEQIEKFRKPGTLVTSNTSGIPIHFMSEGRSEDFQQHFCGTH
FFNPARYLKLFEIIPGPKTSTEVLDFLNEYGSKFLGKTSVVAKDTPAFIGNRIGIYGIQSLFHLVKEMGLTIEEVDKLTG
PVIGRPKSATFRTVDVVGLDTLVHVANGIYENCPNDEQHELFKLPDFINKMMENNWLGSKTGQGFYKKVDKDILSLDLNT
LEYRAAKKANFATLELTKTIDKPINRFKVLVKGTDKAGEFYRKSFAGMFAYVSNRVPEISDELYKIDDAMKAGFGWENGP
FEIWDAIGVAKGIEIMKAEGLEPAAWVTEMLASGSDSFYTVKEGATYFYNIPTKSQVKVPGQDSFIILNNIRESKKVWSN
SGAIIQDLGDGILNLEFQSKMNTIGGDVLTAINKAIDLSEKEYQGLVIGNQAANFSVGANIGMIFMMAVEQEYDELNMAI
KLFQDTMMRVRYSSIPVVVAPHGMTFGGGCEMSLHADKVVAAAETYMGLVEFGVGVIPGGGGSKEMTLRASDLFRKNDVE
LNVLQEYFLTIAMAKVSTSGYEAFDTGLLQHGKDVIVVNKDRQIAEAKKHALLLAEAGYTQPIRRNDIKVLGKQALGMFL
VGTDQMQAGKYISEHDKKIANKLAYVMAGGDLSEATLVSEQYLLDIEREAFLSLCTERKTLERIQYMLTKGKPLRN
>Mature_796_residues
MKRTIKKVAVIGSGIMGSGIACHFANIGVEVLLLDIVPRELTEAEAKKGLTLESKAVRNRVVNEHLANSLKSKPSPIYSQ
KFANRITTGNTTDDMAKIANVDWIIEVVVERLDIKKLVFEQIEKFRKPGTLVTSNTSGIPIHFMSEGRSEDFQQHFCGTH
FFNPARYLKLFEIIPGPKTSTEVLDFLNEYGSKFLGKTSVVAKDTPAFIGNRIGIYGIQSLFHLVKEMGLTIEEVDKLTG
PVIGRPKSATFRTVDVVGLDTLVHVANGIYENCPNDEQHELFKLPDFINKMMENNWLGSKTGQGFYKKVDKDILSLDLNT
LEYRAAKKANFATLELTKTIDKPINRFKVLVKGTDKAGEFYRKSFAGMFAYVSNRVPEISDELYKIDDAMKAGFGWENGP
FEIWDAIGVAKGIEIMKAEGLEPAAWVTEMLASGSDSFYTVKEGATYFYNIPTKSQVKVPGQDSFIILNNIRESKKVWSN
SGAIIQDLGDGILNLEFQSKMNTIGGDVLTAINKAIDLSEKEYQGLVIGNQAANFSVGANIGMIFMMAVEQEYDELNMAI
KLFQDTMMRVRYSSIPVVVAPHGMTFGGGCEMSLHADKVVAAAETYMGLVEFGVGVIPGGGGSKEMTLRASDLFRKNDVE
LNVLQEYFLTIAMAKVSTSGYEAFDTGLLQHGKDVIVVNKDRQIAEAKKHALLLAEAGYTQPIRRNDIKVLGKQALGMFL
VGTDQMQAGKYISEHDKKIANKLAYVMAGGDLSEATLVSEQYLLDIEREAFLSLCTERKTLERIQYMLTKGKPLRN

Specific function: Involved in the degradation of long-chain fatty acids [H]

COG id: COG1250

COG function: function code I; 3-hydroxyacyl-CoA dehydrogenase

Gene ontology:

Cell location: Mitochondria or Peroxisomes [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI296179429, Length=308, Percent_Identity=32.7922077922078, Blast_Score=142, Evalue=1e-33,
Organism=Homo sapiens, GI296179427, Length=325, Percent_Identity=31.3846153846154, Blast_Score=135, Evalue=2e-31,
Organism=Homo sapiens, GI261878539, Length=326, Percent_Identity=28.2208588957055, Blast_Score=96, Evalue=2e-19,
Organism=Homo sapiens, GI68989263, Length=326, Percent_Identity=28.2208588957055, Blast_Score=96, Evalue=2e-19,
Organism=Homo sapiens, GI20127408, Length=327, Percent_Identity=27.217125382263, Blast_Score=89, Evalue=2e-17,
Organism=Escherichia coli, GI1787661, Length=307, Percent_Identity=30.9446254071661, Blast_Score=117, Evalue=4e-27,
Organism=Escherichia coli, GI1790281, Length=304, Percent_Identity=33.2236842105263, Blast_Score=116, Evalue=5e-27,
Organism=Escherichia coli, GI1788682, Length=307, Percent_Identity=28.3387622149837, Blast_Score=80, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17553560, Length=306, Percent_Identity=32.6797385620915, Blast_Score=140, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI17549919, Length=303, Percent_Identity=31.6831683168317, Blast_Score=135, Evalue=8e-32,
Organism=Caenorhabditis elegans, GI17508951, Length=303, Percent_Identity=30.3630363036304, Blast_Score=106, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI25144276, Length=303, Percent_Identity=30.3630363036304, Blast_Score=106, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI17558304, Length=263, Percent_Identity=34.2205323193916, Blast_Score=106, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI17508953, Length=303, Percent_Identity=30.3630363036304, Blast_Score=105, Evalue=7e-23,
Organism=Caenorhabditis elegans, GI71985923, Length=311, Percent_Identity=28.2958199356913, Blast_Score=100, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI17563036, Length=299, Percent_Identity=29.0969899665552, Blast_Score=96, Evalue=9e-20,
Organism=Caenorhabditis elegans, GI71985930, Length=320, Percent_Identity=26.875, Blast_Score=86, Evalue=6e-17,
Organism=Drosophila melanogaster, GI19921000, Length=449, Percent_Identity=24.4988864142539, Blast_Score=92, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24583077, Length=449, Percent_Identity=24.4988864142539, Blast_Score=92, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24583079, Length=449, Percent_Identity=24.4988864142539, Blast_Score=92, Evalue=1e-18,
Organism=Drosophila melanogaster, GI45549573, Length=257, Percent_Identity=25.2918287937743, Blast_Score=84, Evalue=5e-16,
Organism=Drosophila melanogaster, GI20129993, Length=243, Percent_Identity=26.3374485596708, Blast_Score=70, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006176
- InterPro:   IPR006108
- InterPro:   IPR008927
- InterPro:   IPR001753
- InterPro:   IPR013328
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00725 3HCDH; PF02737 3HCDH_N; PF00378 ECH [H]

EC number: =1.1.1.35 [H]

Molecular weight: Translated: 88172; Mature: 88172

Theoretical pI: Translated: 6.85; Mature: 6.85

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRTIKKVAVIGSGIMGSGIACHFANIGVEVLLLDIVPRELTEAEAKKGLTLESKAVRNR
CCHHHHHHHHHCCCCCCCCCEEEEHHCCCEEEEEHHCCHHHHHHHHHCCCCCHHHHHHHH
VVNEHLANSLKSKPSPIYSQKFANRITTGNTTDDMAKIANVDWIIEVVVERLDIKKLVFE
HHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHH
QIEKFRKPGTLVTSNTSGIPIHFMSEGRSEDFQQHFCGTHFFNPARYLKLFEIIPGPKTS
HHHHHCCCCCEEECCCCCCEEEEECCCCCHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCH
TEVLDFLNEYGSKFLGKTSVVAKDTPAFIGNRIGIYGIQSLFHLVKEMGLTIEEVDKLTG
HHHHHHHHHHHHHHCCCCCEEECCCCHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHCC
PVIGRPKSATFRTVDVVGLDTLVHVANGIYENCPNDEQHELFKLPDFINKMMENNWLGSK
CCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCC
TGQGFYKKVDKDILSLDLNTLEYRAAKKANFATLELTKTIDKPINRFKVLVKGTDKAGEF
CCCHHHHHHHHHHHHHCCHHHHHHHHCCCCCEEEEHHHHHHHHHHHEEEEEECCCHHHHH
YRKSFAGMFAYVSNRVPEISDELYKIDDAMKAGFGWENGPFEIWDAIGVAKGIEIMKAEG
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCHHHHCCC
LEPAAWVTEMLASGSDSFYTVKEGATYFYNIPTKSQVKVPGQDSFIILNNIRESKKVWSN
CCHHHHHHHHHHCCCCCEEEEECCCEEEEECCCCCEEECCCCCCEEEECCCHHHHHHHCC
SGAIIQDLGDGILNLEFQSKMNTIGGDVLTAINKAIDLSEKEYQGLVIGNQAANFSVGAN
CCCCHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCCHHCCCEEEECCCCCCCCCCC
IGMIFMMAVEQEYDELNMAIKLFQDTMMRVRYSSIPVVVAPHGMTFGGGCEMSLHADKVV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCEECCCCEEEECHHHHH
AAAETYMGLVEFGVGVIPGGGGSKEMTLRASDLFRKNDVELNVLQEYFLTIAMAKVSTSG
HHHHHHHHHHHHCCEEECCCCCCCEEEEEHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCC
YEAFDTGLLQHGKDVIVVNKDRQIAEAKKHALLLAEAGYTQPIRRNDIKVLGKQALGMFL
CHHHHHHHHHCCCEEEEECCCHHHHHHHHHEEEEEECCCCCCCCCCHHHHHHHHHCCEEE
VGTDQMQAGKYISEHDKKIANKLAYVMAGGDLSEATLVSEQYLLDIEREAFLSLCTERKT
EECCCHHHCCHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LERIQYMLTKGKPLRN
HHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKRTIKKVAVIGSGIMGSGIACHFANIGVEVLLLDIVPRELTEAEAKKGLTLESKAVRNR
CCHHHHHHHHHCCCCCCCCCEEEEHHCCCEEEEEHHCCHHHHHHHHHCCCCCHHHHHHHH
VVNEHLANSLKSKPSPIYSQKFANRITTGNTTDDMAKIANVDWIIEVVVERLDIKKLVFE
HHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHH
QIEKFRKPGTLVTSNTSGIPIHFMSEGRSEDFQQHFCGTHFFNPARYLKLFEIIPGPKTS
HHHHHCCCCCEEECCCCCCEEEEECCCCCHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCH
TEVLDFLNEYGSKFLGKTSVVAKDTPAFIGNRIGIYGIQSLFHLVKEMGLTIEEVDKLTG
HHHHHHHHHHHHHHCCCCCEEECCCCHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHCC
PVIGRPKSATFRTVDVVGLDTLVHVANGIYENCPNDEQHELFKLPDFINKMMENNWLGSK
CCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCC
TGQGFYKKVDKDILSLDLNTLEYRAAKKANFATLELTKTIDKPINRFKVLVKGTDKAGEF
CCCHHHHHHHHHHHHHCCHHHHHHHHCCCCCEEEEHHHHHHHHHHHEEEEEECCCHHHHH
YRKSFAGMFAYVSNRVPEISDELYKIDDAMKAGFGWENGPFEIWDAIGVAKGIEIMKAEG
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCHHHHCCC
LEPAAWVTEMLASGSDSFYTVKEGATYFYNIPTKSQVKVPGQDSFIILNNIRESKKVWSN
CCHHHHHHHHHHCCCCCEEEEECCCEEEEECCCCCEEECCCCCCEEEECCCHHHHHHHCC
SGAIIQDLGDGILNLEFQSKMNTIGGDVLTAINKAIDLSEKEYQGLVIGNQAANFSVGAN
CCCCHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCCHHCCCEEEECCCCCCCCCCC
IGMIFMMAVEQEYDELNMAIKLFQDTMMRVRYSSIPVVVAPHGMTFGGGCEMSLHADKVV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCEECCCCEEEECHHHHH
AAAETYMGLVEFGVGVIPGGGGSKEMTLRASDLFRKNDVELNVLQEYFLTIAMAKVSTSG
HHHHHHHHHHHHCCEEECCCCCCCEEEEEHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCC
YEAFDTGLLQHGKDVIVVNKDRQIAEAKKHALLLAEAGYTQPIRRNDIKVLGKQALGMFL
CHHHHHHHHHCCCEEEEECCCHHHHHHHHHEEEEEECCCCCCCCCCHHHHHHHHHCCEEE
VGTDQMQAGKYISEHDKKIANKLAYVMAGGDLSEATLVSEQYLLDIEREAFLSLCTERKT
EECCCHHHCCHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LERIQYMLTKGKPLRN
HHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]