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The map label for this gene is nreC [H]

Identifier: 146302391

GI number: 146302391

Start: 5641443

End: 5642102

Strand: Direct

Name: nreC [H]

Synonym: Fjoh_4664

Alternate gene names: 146302391

Gene position: 5641443-5642102 (Clockwise)

Preceding gene: 146302390

Following gene: 146302392

Centisome position: 92.53

GC content: 31.97

Gene sequence:

>660_bases
ATGACTAAAATAAAAATACATCTTGCCGATGATCATCAGGTACTGATCGACGGACTGACCAATTTATTACAAACGGTTTC
AAACTTTGAAATTGTGGGCAGTTCATTGAATGGTGTAACTGTATATGATGATGTAATTCAAGACCAGGCTGATATTCTTG
TTTTAGATATTAGTATGCCTCAAAAAGACGGGATTGAAGTTTTAAAAGAATTCAATCAAAAAGGTCTGCCTTGCAAAGTC
ATTATTTTATCGAGTTATGACGACCTGAAAATCATTAAAGAAGTAATGAAACTGGGTGCTAAAGGTTATTTGACAAAAAA
ATGTGCCGGAGAAAATATGATTGAAGCTATAGAAGCTGTTTATGAAGGGCAGGAATATTTTTCGGATGCAGTGAGAGAAA
AAATATTCAGCATGTTTTCTCAAAACAACCCAAAACTGAATAAGAATGTTTATATCGAAAATCCTATTTTAAGTCCGAGA
GAAATTGAAATCGTAACCTTAATTTGTCTGGAATACAGTGGAAAAGAAATAAGCGAAAAGCTATTCATTAGTGTAAACAC
TGTCGAAACACACCGAAAAAACATTATGAAAAAGCTCAACATAAAAAATACTATCGGACTTGTAAAATATGCTTTAAAAA
ACAATTTAATTAACGAGTAA

Upstream 100 bases:

>100_bases
CTTATTTTTCTCTTAAACAGAATATCCCAAATCATTTCCAAATATCATTTTTGTAAGATATTTTATTCATAAATTTGCAT
TTTGTGCAAAGAAGCATTTT

Downstream 100 bases:

>100_bases
TTCAATTGAGAAACATTCAAAATCAAATAAAATCTATGTCTTTTATTAGAGTTTTCATATTAGTATTTTTCTTTGTTCCA
ATTGAAAATAAAGCTTTTAG

Product: two component LuxR family transcriptional regulator

Products: NA

Alternate protein names: Nitrogen regulation protein C [H]

Number of amino acids: Translated: 219; Mature: 218

Protein sequence:

>219_residues
MTKIKIHLADDHQVLIDGLTNLLQTVSNFEIVGSSLNGVTVYDDVIQDQADILVLDISMPQKDGIEVLKEFNQKGLPCKV
IILSSYDDLKIIKEVMKLGAKGYLTKKCAGENMIEAIEAVYEGQEYFSDAVREKIFSMFSQNNPKLNKNVYIENPILSPR
EIEIVTLICLEYSGKEISEKLFISVNTVETHRKNIMKKLNIKNTIGLVKYALKNNLINE

Sequences:

>Translated_219_residues
MTKIKIHLADDHQVLIDGLTNLLQTVSNFEIVGSSLNGVTVYDDVIQDQADILVLDISMPQKDGIEVLKEFNQKGLPCKV
IILSSYDDLKIIKEVMKLGAKGYLTKKCAGENMIEAIEAVYEGQEYFSDAVREKIFSMFSQNNPKLNKNVYIENPILSPR
EIEIVTLICLEYSGKEISEKLFISVNTVETHRKNIMKKLNIKNTIGLVKYALKNNLINE
>Mature_218_residues
TKIKIHLADDHQVLIDGLTNLLQTVSNFEIVGSSLNGVTVYDDVIQDQADILVLDISMPQKDGIEVLKEFNQKGLPCKVI
ILSSYDDLKIIKEVMKLGAKGYLTKKCAGENMIEAIEAVYEGQEYFSDAVREKIFSMFSQNNPKLNKNVYIENPILSPRE
IEIVTLICLEYSGKEISEKLFISVNTVETHRKNIMKKLNIKNTIGLVKYALKNNLINE

Specific function: Member of the two-component regulatory system nreB/nreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. Phosphorylated nreC binds to a GC-rich palindromic sequence at the promoters of the nitrate (narGHJI) and nit

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788222, Length=215, Percent_Identity=28.8372093023256, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1790102, Length=206, Percent_Identity=27.1844660194175, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1788521, Length=211, Percent_Identity=27.9620853080569, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1788712, Length=207, Percent_Identity=30.4347826086957, Blast_Score=87, Evalue=8e-19,
Organism=Escherichia coli, GI1788546, Length=213, Percent_Identity=24.8826291079812, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1786747, Length=212, Percent_Identity=27.8301886792453, Blast_Score=77, Evalue=6e-16,
Organism=Escherichia coli, GI1787473, Length=186, Percent_Identity=27.4193548387097, Blast_Score=72, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 24755; Mature: 24624

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKIKIHLADDHQVLIDGLTNLLQTVSNFEIVGSSLNGVTVYDDVIQDQADILVLDISMP
CCEEEEEECCCCHHHHHHHHHHHHHHHCHHEECCCCCCEEEEHHHHCCCCCEEEEEECCC
QKDGIEVLKEFNQKGLPCKVIILSSYDDLKIIKEVMKLGAKGYLTKKCAGENMIEAIEAV
CCCHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHHHCCCCCCCHHHHCCCHHHHHHHHH
YEGQEYFSDAVREKIFSMFSQNNPKLNKNVYIENPILSPREIEIVTLICLEYSGKEISEK
HCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCEEEEEEEEEECCCCCCCCE
LFISVNTVETHRKNIMKKLNIKNTIGLVKYALKNNLINE
EEEEEEHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TKIKIHLADDHQVLIDGLTNLLQTVSNFEIVGSSLNGVTVYDDVIQDQADILVLDISMP
CEEEEEECCCCHHHHHHHHHHHHHHHCHHEECCCCCCEEEEHHHHCCCCCEEEEEECCC
QKDGIEVLKEFNQKGLPCKVIILSSYDDLKIIKEVMKLGAKGYLTKKCAGENMIEAIEAV
CCCHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHHHCCCCCCCHHHHCCCHHHHHHHHH
YEGQEYFSDAVREKIFSMFSQNNPKLNKNVYIENPILSPREIEIVTLICLEYSGKEISEK
HCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCEEEEEEEEEECCCCCCCCE
LFISVNTVETHRKNIMKKLNIKNTIGLVKYALKNNLINE
EEEEEEHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12426351 [H]