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The map label for this gene is moeZ [H]

Identifier: 146302366

GI number: 146302366

Start: 5608618

End: 5609685

Strand: Reverse

Name: moeZ [H]

Synonym: Fjoh_4639

Alternate gene names: 146302366

Gene position: 5609685-5608618 (Counterclockwise)

Preceding gene: 146302367

Following gene: 146302365

Centisome position: 92.01

GC content: 33.24

Gene sequence:

>1068_bases
ATGGAAACATCAAATCGATATAACCGACAAATGATTCTTCCTGAAATTGGGGAAGGTGGGCAGGACAAATTAGCAAAAGC
TAAAGTTTTGGTTATTGGCGCCGGAGGTTTGGGCGCAGCAATTCTGCCGTATTTAGCTGCAGCTGGAGTAGGAGAAATTG
GAATTGTTGATGATGATGTTATTGAGATTTCAAACCTACACCGTCAGGTAATTTACAAAAGTTCGGCAGTTGGAAAATCT
AAAGCAAAAGAAGCCAAACAAATGATTTCTGAATTGAATCCGCTGGTAAAAGTAAAAGCCATTTCGGAGAAATTATCAGG
AAAAAATGTTCTTAGTTTATTCGAAAAATATGATATTGTTGTCGATGCAACTGATAGTATTTCGATAAAATATCTCATAA
ACGATGCTTGCTTAGTAACGAATAAACCAATGGTTTACGGATCGATTTTTAGATTTCAGGGACAGGTTTCGGTTTTCAAT
TATGAAAACGGACCAACGTACAGATGTTTGTATCCAGATGAAAACTCGAATGCTTTAAATTGTGAAGATGCAGGCGTAAT
TGGAGTTTCAGTTGGAATTATTGGAATGTTCCAGGCCAATGAAGTTTTAAAAATGATTCTCGGAATTGGAGAAGTTTTGA
GCGGTAAAATATTAGTCTATAATGTTTTGAATAACGAACAGCAAAAATATGATTTTGATAAAAGTGATTTTCAACCCATA
AGCAGAGAAACATTCGAAGAAAAATACAATAAATGGGAAGTTGAAGAAGTAAGATTCGAATCTGTTTTAGATGAAATAAA
CCAAGATGAGGTGCTTTTTCTTGATGTTAGAAATATTGATGAATCGCCAAAAATTACTTTGCAAAATCAATTCCAGATTC
CGTTAATGCATTTAGAAAAAGAAATCGAAAAATTGAATAAAAACCAAACGATTTATATTTTCTGCCAATCTGGAATAAGA
AGTAAAATCGCAGTAGAATTGCTTCAAAAGCATCAATTTAAAAATGTAAAAAGTATTGCTGGAGGGGCTTTAGCAATGAA
ACAATTATTACAAGAAATAAAAATATAG

Upstream 100 bases:

>100_bases
TGGCAGTCAATCAAAAAATAATTTCAAAAAAAGCAGATTACACTTTACAGACAAGTGATATTGTTGCTTTATTACCGCCG
TTTGCAGGAGGATAAAGAGT

Downstream 100 bases:

>100_bases
CTACAGATTTTAAAATGTTCGTCTAGTTTGTCATTTCGACGAAGGAGAAATGACAATATTGAGGTTAACTTTCGTTGCTA
TAAAATATAATTAGTGAAAA

Product: UBA/THIF-type NAD/FAD binding protein

Products: NA

Alternate protein names: Sulfur carrier protein CysO adenylyltransferase; Sulfur carrier protein CysO sulfurtransferase [H]

Number of amino acids: Translated: 355; Mature: 355

Protein sequence:

>355_residues
METSNRYNRQMILPEIGEGGQDKLAKAKVLVIGAGGLGAAILPYLAAAGVGEIGIVDDDVIEISNLHRQVIYKSSAVGKS
KAKEAKQMISELNPLVKVKAISEKLSGKNVLSLFEKYDIVVDATDSISIKYLINDACLVTNKPMVYGSIFRFQGQVSVFN
YENGPTYRCLYPDENSNALNCEDAGVIGVSVGIIGMFQANEVLKMILGIGEVLSGKILVYNVLNNEQQKYDFDKSDFQPI
SRETFEEKYNKWEVEEVRFESVLDEINQDEVLFLDVRNIDESPKITLQNQFQIPLMHLEKEIEKLNKNQTIYIFCQSGIR
SKIAVELLQKHQFKNVKSIAGGALAMKQLLQEIKI

Sequences:

>Translated_355_residues
METSNRYNRQMILPEIGEGGQDKLAKAKVLVIGAGGLGAAILPYLAAAGVGEIGIVDDDVIEISNLHRQVIYKSSAVGKS
KAKEAKQMISELNPLVKVKAISEKLSGKNVLSLFEKYDIVVDATDSISIKYLINDACLVTNKPMVYGSIFRFQGQVSVFN
YENGPTYRCLYPDENSNALNCEDAGVIGVSVGIIGMFQANEVLKMILGIGEVLSGKILVYNVLNNEQQKYDFDKSDFQPI
SRETFEEKYNKWEVEEVRFESVLDEINQDEVLFLDVRNIDESPKITLQNQFQIPLMHLEKEIEKLNKNQTIYIFCQSGIR
SKIAVELLQKHQFKNVKSIAGGALAMKQLLQEIKI
>Mature_355_residues
METSNRYNRQMILPEIGEGGQDKLAKAKVLVIGAGGLGAAILPYLAAAGVGEIGIVDDDVIEISNLHRQVIYKSSAVGKS
KAKEAKQMISELNPLVKVKAISEKLSGKNVLSLFEKYDIVVDATDSISIKYLINDACLVTNKPMVYGSIFRFQGQVSVFN
YENGPTYRCLYPDENSNALNCEDAGVIGVSVGIIGMFQANEVLKMILGIGEVLSGKILVYNVLNNEQQKYDFDKSDFQPI
SRETFEEKYNKWEVEEVRFESVLDEINQDEVLFLDVRNIDESPKITLQNQFQIPLMHLEKEIEKLNKNQTIYIFCQSGIR
SKIAVELLQKHQFKNVKSIAGGALAMKQLLQEIKI

Specific function: Catalyzes the conversion of the sulfur carrier protein CysO to CysO-thiocarboxylate. The reaction is thought to proceed in two steps:first, ATP-dependent activation of CysO as acyl- adenylate (CysO-COOAMP), followed by sulfur transfer to give CysO- thioca

COG id: COG0476

COG function: function code H; Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 rhodanese domain [H]

Homologues:

Organism=Homo sapiens, GI7657339, Length=389, Percent_Identity=33.9331619537275, Blast_Score=210, Evalue=2e-54,
Organism=Homo sapiens, GI4885649, Length=147, Percent_Identity=29.2517006802721, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI23510338, Length=167, Percent_Identity=28.1437125748503, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI23510340, Length=167, Percent_Identity=28.1437125748503, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI38045948, Length=167, Percent_Identity=31.1377245508982, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI38045942, Length=134, Percent_Identity=33.5820895522388, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI38045944, Length=134, Percent_Identity=33.5820895522388, Blast_Score=73, Evalue=4e-13,
Organism=Escherichia coli, GI1787048, Length=222, Percent_Identity=37.8378378378378, Blast_Score=183, Evalue=1e-47,
Organism=Escherichia coli, GI87082356, Length=238, Percent_Identity=34.8739495798319, Blast_Score=156, Evalue=2e-39,
Organism=Escherichia coli, GI1789177, Length=130, Percent_Identity=30, Blast_Score=61, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI17540406, Length=361, Percent_Identity=33.7950138504155, Blast_Score=200, Evalue=8e-52,
Organism=Caenorhabditis elegans, GI193203301, Length=151, Percent_Identity=32.4503311258278, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI71984476, Length=113, Percent_Identity=37.1681415929204, Blast_Score=74, Evalue=9e-14,
Organism=Saccharomyces cerevisiae, GI6321903, Length=385, Percent_Identity=35.8441558441558, Blast_Score=209, Evalue=5e-55,
Organism=Saccharomyces cerevisiae, GI6322639, Length=166, Percent_Identity=28.3132530120482, Blast_Score=75, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6320598, Length=141, Percent_Identity=29.7872340425532, Blast_Score=71, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6325323, Length=111, Percent_Identity=34.2342342342342, Blast_Score=66, Evalue=9e-12,
Organism=Drosophila melanogaster, GI24582879, Length=374, Percent_Identity=35.5614973262032, Blast_Score=224, Evalue=5e-59,
Organism=Drosophila melanogaster, GI24660640, Length=162, Percent_Identity=32.0987654320988, Blast_Score=99, Evalue=6e-21,
Organism=Drosophila melanogaster, GI20129973, Length=147, Percent_Identity=33.3333333333333, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI28573937, Length=162, Percent_Identity=30.8641975308642, Blast_Score=75, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007901
- InterPro:   IPR009036
- InterPro:   IPR016040
- InterPro:   IPR001763
- InterPro:   IPR000594 [H]

Pfam domain/function: PF05237 MoeZ_MoeB; PF00581 Rhodanese; PF00899 ThiF [H]

EC number: NA

Molecular weight: Translated: 39681; Mature: 39681

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: PS50206 RHODANESE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METSNRYNRQMILPEIGEGGQDKLAKAKVLVIGAGGLGAAILPYLAAAGVGEIGIVDDDV
CCCCCCCCCEEECCCCCCCCHHHHCEEEEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCH
IEISNLHRQVIYKSSAVGKSKAKEAKQMISELNPLVKVKAISEKLSGKNVLSLFEKYDIV
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHEEEHHHHHHHCCHHHHHHHHHCCEE
VDATDSISIKYLINDACLVTNKPMVYGSIFRFQGQVSVFNYENGPTYRCLYPDENSNALN
EECCCCEEEEEEECCEEEEECCCEEEEEEEEEECEEEEEEECCCCEEEEECCCCCCCEEC
CEDAGVIGVSVGIIGMFQANEVLKMILGIGEVLSGKILVYNVLNNEQQKYDFDKSDFQPI
CCCCCEEEEEEHEEEEHHHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHCCCCCCCCCCC
SRETFEEKYNKWEVEEVRFESVLDEINQDEVLFLDVRNIDESPKITLQNQFQIPLMHLEK
HHHHHHHHHCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCEEECCCCCCHHHHHHH
EIEKLNKNQTIYIFCQSGIRSKIAVELLQKHQFKNVKSIAGGALAMKQLLQEIKI
HHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCC
>Mature Secondary Structure
METSNRYNRQMILPEIGEGGQDKLAKAKVLVIGAGGLGAAILPYLAAAGVGEIGIVDDDV
CCCCCCCCCEEECCCCCCCCHHHHCEEEEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCH
IEISNLHRQVIYKSSAVGKSKAKEAKQMISELNPLVKVKAISEKLSGKNVLSLFEKYDIV
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHEEEHHHHHHHCCHHHHHHHHHCCEE
VDATDSISIKYLINDACLVTNKPMVYGSIFRFQGQVSVFNYENGPTYRCLYPDENSNALN
EECCCCEEEEEEECCEEEEECCCEEEEEEEEEECEEEEEEECCCCEEEEECCCCCCCEEC
CEDAGVIGVSVGIIGMFQANEVLKMILGIGEVLSGKILVYNVLNNEQQKYDFDKSDFQPI
CCCCCEEEEEEHEEEEHHHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHCCCCCCCCCCC
SRETFEEKYNKWEVEEVRFESVLDEINQDEVLFLDVRNIDESPKITLQNQFQIPLMHLEK
HHHHHHHHHCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCEEECCCCCCHHHHHHH
EIEKLNKNQTIYIFCQSGIRSKIAVELLQKHQFKNVKSIAGGALAMKQLLQEIKI
HHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]