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The map label for this gene is mdaB [H]

Identifier: 146302344

GI number: 146302344

Start: 5581943

End: 5582548

Strand: Direct

Name: mdaB [H]

Synonym: Fjoh_4617

Alternate gene names: 146302344

Gene position: 5581943-5582548 (Clockwise)

Preceding gene: 146302343

Following gene: 146302345

Centisome position: 91.55

GC content: 35.64

Gene sequence:

>606_bases
ATGAAAAAGATATTTATAATTAACGGCGGACAAAAATTCGCGCATTCAGGAGGACAATTCAATAAAACCGTTCAGGATTG
GACAGTTGAATTTCTTTCTAAAAACAATAATTACGAAATAAAAACAACTCACATTGAAGACGAAATAGATCTTCAAAAAG
AAGTAGAAAAATTCGTTTGGGCAGATTTAATTATCTATCACACACCCGTTTGGTGGTTTCAAATTCCTAATCTTTTCAAA
AAATATATCGATGATGTTTTCACGCAAGGACACAACAACGGAATCTACAAAAGCGACGGAAGAAGCCGTGTAAACCCAGA
CATCAATTACGGAACCGGCGGACTTTTACACGGACGCAAATACATGCTTACTACAAGCTGGAATGCACCTGCAACAGCAT
TTACACTTCCGGGGGAATTCTTTGAAGAAACTTCTGTTGATGACGGCGTAATGTTTGGTTTCCACAAAATGAACAAATTT
ACCGGAATGGAACGCATAAACGGATTTCATTTTCATGATGTTGAAAAAGGTGCAACACCAGAAAATATTGTTATCTTTAA
AGAACAGTACACCAAACATTTAGAAGAAACCTTTAAAACTTTATAA

Upstream 100 bases:

>100_bases
TTAAAAAAAATCTCAAAAATTAAATAATTAGAATTTGGGCGTGCCCTTCTGGGTCGGGCTTACCCTCACGCGTCCATTTT
CAAAAGAAACAACAATAAAA

Downstream 100 bases:

>100_bases
TTATGATCTCAATCACCGCAATCATTAAAAGTAAAAAAGAAAATCTTATAGAAGTTCAAAATATGATTACACATCTGGTT
ACAGAAACCAGAAAAGAAGA

Product: NAD(P)H dehydrogenase (quinone)

Products: NADP; a reduced quinone; reduced acceptor [C]

Alternate protein names: NA

Number of amino acids: Translated: 201; Mature: 201

Protein sequence:

>201_residues
MKKIFIINGGQKFAHSGGQFNKTVQDWTVEFLSKNNNYEIKTTHIEDEIDLQKEVEKFVWADLIIYHTPVWWFQIPNLFK
KYIDDVFTQGHNNGIYKSDGRSRVNPDINYGTGGLLHGRKYMLTTSWNAPATAFTLPGEFFEETSVDDGVMFGFHKMNKF
TGMERINGFHFHDVEKGATPENIVIFKEQYTKHLEETFKTL

Sequences:

>Translated_201_residues
MKKIFIINGGQKFAHSGGQFNKTVQDWTVEFLSKNNNYEIKTTHIEDEIDLQKEVEKFVWADLIIYHTPVWWFQIPNLFK
KYIDDVFTQGHNNGIYKSDGRSRVNPDINYGTGGLLHGRKYMLTTSWNAPATAFTLPGEFFEETSVDDGVMFGFHKMNKF
TGMERINGFHFHDVEKGATPENIVIFKEQYTKHLEETFKTL
>Mature_201_residues
MKKIFIINGGQKFAHSGGQFNKTVQDWTVEFLSKNNNYEIKTTHIEDEIDLQKEVEKFVWADLIIYHTPVWWFQIPNLFK
KYIDDVFTQGHNNGIYKSDGRSRVNPDINYGTGGLLHGRKYMLTTSWNAPATAFTLPGEFFEETSVDDGVMFGFHKMNKF
TGMERINGFHFHDVEKGATPENIVIFKEQYTKHLEETFKTL

Specific function: Unknown

COG id: COG2249

COG function: function code R; Putative NADPH-quinone reductase (modulator of drug activity B)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: To H.influenzae HI_0648 and S.pombe SPAC5H10.05c [H]

Homologues:

Organism=Escherichia coli, GI1789406, Length=198, Percent_Identity=43.9393939393939, Blast_Score=171, Evalue=4e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003680 [H]

Pfam domain/function: PF02525 Flavodoxin_2 [H]

EC number: NA

Molecular weight: Translated: 23400; Mature: 23400

Theoretical pI: Translated: 6.61; Mature: 6.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKIFIINGGQKFAHSGGQFNKTVQDWTVEFLSKNNNYEIKTTHIEDEIDLQKEVEKFVW
CCEEEEEECCHHHHCCCCCCCCHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHH
ADLIIYHTPVWWFQIPNLFKKYIDDVFTQGHNNGIYKSDGRSRVNPDINYGTGGLLHGRK
HHHHHHCCCHHEEHHHHHHHHHHHHHHHCCCCCCCEECCCCCCCCCCCCCCCCCEECCCE
YMLTTSWNAPATAFTLPGEFFEETSVDDGVMFGFHKMNKFTGMERINGFHFHDVEKGATP
EEEEECCCCCCEEEECCHHHHHHCCCCCCEEEHHHHHHHHHHHHHHCCCEEECCCCCCCC
ENIVIFKEQYTKHLEETFKTL
CEEEEEHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKKIFIINGGQKFAHSGGQFNKTVQDWTVEFLSKNNNYEIKTTHIEDEIDLQKEVEKFVW
CCEEEEEECCHHHHCCCCCCCCHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHH
ADLIIYHTPVWWFQIPNLFKKYIDDVFTQGHNNGIYKSDGRSRVNPDINYGTGGLLHGRK
HHHHHHCCCHHEEHHHHHHHHHHHHHHHCCCCCCCEECCCCCCCCCCCCCCCCCEECCCE
YMLTTSWNAPATAFTLPGEFFEETSVDDGVMFGFHKMNKFTGMERINGFHFHDVEKGATP
EEEEECCCCCCEEEECCHHHHHHCCCCCCEEEHHHHHHHHHHHHHHCCCEEECCCCCCCC
ENIVIFKEQYTKHLEETFKTL
CEEEEEHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NADPH; a quinone; Acceptor; NADPH [C]

Specific reaction: NADPH + a quinone = NADP + a reduced quinone Acceptor + NADPH = reduced acceptor + NADP [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]