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The map label for this gene is hutI

Identifier: 146302297

GI number: 146302297

Start: 5527114

End: 5528349

Strand: Direct

Name: hutI

Synonym: Fjoh_4570

Alternate gene names: 146302297

Gene position: 5527114-5528349 (Clockwise)

Preceding gene: 146302296

Following gene: 146302299

Centisome position: 90.65

GC content: 36.33

Gene sequence:

>1236_bases
ATGATTACATTAATAAAAAACATACAGGAACTGCTCCAAGTACGCCAAACATCAATTTCTAAAGTTTCGGGAGCTGAAAT
GGCAGAGCTTCCTACAATTAAAAATGCCTTTTTAGTAATAAAAGATGATCTTATTGCTGATTTTGGATCTATGGAAAACC
TTCCAGAAATTAAAGCAGACAGCATTATCAATGCTTCCGGACGTGTTGTTCTTCCTGCCTGGTGCGACAGCCATACGCAT
ATTGTGTATGCGGGAAACCGCGAACAGGAATTTGTAGACCGCATAAACGGATTTACTTATGAAGAAATTGCCAATCGTGG
CGGCGGAATTTTAAATTCGGCTAAAAAATTAAATGAAACTTCTGAAGAAGAAATTTACGAACAATCAAAAATTCGTCTGG
AAGAAGTCATGCGTTTAGGAACCGGAGCTGTCGAAATAAAATCAGGTTACGGATTAACTGTTGAAGGCGAATTAAAAATG
CTTCGTGTGATAAAAAAACTGGCAGAAAATTATCCAATTTCAATAAAAGCTACTTTTTTGGGCGCACATGCTTTCCCAAC
GCATTATAAAGAAAACAAGGCAGGTTATATTGATGAAATCATCACTAAAATGCTTCCTGAAATTGCACAAAACAAACTGG
CAGATTATGTAGATGTTTTCTGCGAAAGCGGTTATTTCTCTGTTGAAGAAACAGAAAAAATCATGCAGGCGGGAATTGAT
TTTGGTTTAAAACCAAAAATTCACGTTAATCAATTTAATTCTATCGGCGGTATTCAGTCTGGAGTTAAATTTAACGCACT
TTCTGTAGATCATCTTGAAATAATGAATCCAGAAGACATTGAAGCCTTAAAAGGCACCGAAACGATGCCTGTCGCATTAC
CTTCATGTTCTTATTTCTTAAGCATTCCGTACACACCAGCACGCGAAATGATTAAAGCAGGATTACCTTTGGCACTTGCA
ACCGATTTCAATCCTGGTTCTACTCCATCCGGGAACATGAATTTTGTTGTAGCTACAGCTTGTATTAAAATGAAAATGAC
TCCTGAAGAAGCAATAAACGCGGCAACAATTAACGGCGCTTATGCAATGGGACTTTCAGAAACTCACGGAAGTATTACAA
AAGGCAAAAAAGCCAATTTAATTATAACTAAACCTATTTCATCTTACTACCAAATTCCTTATGCTTTTGGAAGTAATTTA
ATTGAAGATGTTTTAATTGACGGTCAAATTATATAA

Upstream 100 bases:

>100_bases
CTGAATAAAAACACAAAAGAATTAAAAATACGAATTTCACAGATTTCACGGATTAGTTCGTGATAATTTGTGAAATTTGT
GTTTTATAACACTATCTATA

Downstream 100 bases:

>100_bases
TAAAATTAATCCTTTTCAAAATTATTTAACCCACAGCTCAAAACTGTGGGTTATTTTTTACTGCAATGTTTAAAATCGGT
GCAAATACCATAAGTTTTAC

Product: imidazolonepropionase

Products: NA

Alternate protein names: Imidazolone-5-propionate hydrolase

Number of amino acids: Translated: 411; Mature: 411

Protein sequence:

>411_residues
MITLIKNIQELLQVRQTSISKVSGAEMAELPTIKNAFLVIKDDLIADFGSMENLPEIKADSIINASGRVVLPAWCDSHTH
IVYAGNREQEFVDRINGFTYEEIANRGGGILNSAKKLNETSEEEIYEQSKIRLEEVMRLGTGAVEIKSGYGLTVEGELKM
LRVIKKLAENYPISIKATFLGAHAFPTHYKENKAGYIDEIITKMLPEIAQNKLADYVDVFCESGYFSVEETEKIMQAGID
FGLKPKIHVNQFNSIGGIQSGVKFNALSVDHLEIMNPEDIEALKGTETMPVALPSCSYFLSIPYTPAREMIKAGLPLALA
TDFNPGSTPSGNMNFVVATACIKMKMTPEEAINAATINGAYAMGLSETHGSITKGKKANLIITKPISSYYQIPYAFGSNL
IEDVLIDGQII

Sequences:

>Translated_411_residues
MITLIKNIQELLQVRQTSISKVSGAEMAELPTIKNAFLVIKDDLIADFGSMENLPEIKADSIINASGRVVLPAWCDSHTH
IVYAGNREQEFVDRINGFTYEEIANRGGGILNSAKKLNETSEEEIYEQSKIRLEEVMRLGTGAVEIKSGYGLTVEGELKM
LRVIKKLAENYPISIKATFLGAHAFPTHYKENKAGYIDEIITKMLPEIAQNKLADYVDVFCESGYFSVEETEKIMQAGID
FGLKPKIHVNQFNSIGGIQSGVKFNALSVDHLEIMNPEDIEALKGTETMPVALPSCSYFLSIPYTPAREMIKAGLPLALA
TDFNPGSTPSGNMNFVVATACIKMKMTPEEAINAATINGAYAMGLSETHGSITKGKKANLIITKPISSYYQIPYAFGSNL
IEDVLIDGQII
>Mature_411_residues
MITLIKNIQELLQVRQTSISKVSGAEMAELPTIKNAFLVIKDDLIADFGSMENLPEIKADSIINASGRVVLPAWCDSHTH
IVYAGNREQEFVDRINGFTYEEIANRGGGILNSAKKLNETSEEEIYEQSKIRLEEVMRLGTGAVEIKSGYGLTVEGELKM
LRVIKKLAENYPISIKATFLGAHAFPTHYKENKAGYIDEIITKMLPEIAQNKLADYVDVFCESGYFSVEETEKIMQAGID
FGLKPKIHVNQFNSIGGIQSGVKFNALSVDHLEIMNPEDIEALKGTETMPVALPSCSYFLSIPYTPAREMIKAGLPLALA
TDFNPGSTPSGNMNFVVATACIKMKMTPEEAINAATINGAYAMGLSETHGSITKGKKANLIITKPISSYYQIPYAFGSNL
IEDVLIDGQII

Specific function: Unknown

COG id: COG1228

COG function: function code Q; Imidazolonepropionase and related amidohydrolases

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hutI family

Homologues:

Organism=Homo sapiens, GI223972677, Length=420, Percent_Identity=36.6666666666667, Blast_Score=239, Evalue=3e-63,
Organism=Caenorhabditis elegans, GI17555004, Length=442, Percent_Identity=30.9954751131222, Blast_Score=226, Evalue=2e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HUTI_FLAJ1 (A5FB49)

Other databases:

- EMBL:   CP000685
- RefSeq:   YP_001196888.1
- ProteinModelPortal:   A5FB49
- SMR:   A5FB49
- STRING:   A5FB49
- GeneID:   5092881
- GenomeReviews:   CP000685_GR
- KEGG:   fjo:Fjoh_4570
- eggNOG:   COG1228
- HOGENOM:   HBG686142
- OMA:   MNMACTL
- ProtClustDB:   PRK09356
- BioCyc:   FJOH376686:FJOH_4570-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00372
- InterPro:   IPR006680
- InterPro:   IPR005920
- InterPro:   IPR011059
- TIGRFAMs:   TIGR01224

Pfam domain/function: PF01979 Amidohydro_1; SSF51338 Metalo_hydrolase

EC number: =3.5.2.7

Molecular weight: Translated: 45076; Mature: 45076

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: NA

Important sites: BINDING 87-87 BINDING 100-100 BINDING 150-150 BINDING 183-183 BINDING 251-251

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITLIKNIQELLQVRQTSISKVSGAEMAELPTIKNAFLVIKDDLIADFGSMENLPEIKAD
CCHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCEEEEEEHHHHHHHCCCCCCCCCCCC
SIINASGRVVLPAWCDSHTHIVYAGNREQEFVDRINGFTYEEIANRGGGILNSAKKLNET
CEECCCCCEEEEEECCCCCEEEEECCCHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHCCC
SEEEIYEQSKIRLEEVMRLGTGAVEIKSGYGLTVEGELKMLRVIKKLAENYPISIKATFL
HHHHHHHHHHHHHHHHHHHCCCEEEEECCCCEEEECHHHHHHHHHHHHCCCCEEEEEEEE
GAHAFPTHYKENKAGYIDEIITKMLPEIAQNKLADYVDVFCESGYFSVEETEKIMQAGID
ECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCC
FGLKPKIHVNQFNSIGGIQSGVKFNALSVDHLEIMNPEDIEALKGTETMPVALPSCSYFL
CCCCCCEEECCCCCCCCCCCCCEEEEEEECCEECCCCCHHHHHCCCCCCEEEECCCEEEE
SIPYTPAREMIKAGLPLALATDFNPGSTPSGNMNFVVATACIKMKMTPEEAINAATINGA
ECCCCCHHHHHHCCCCEEEEECCCCCCCCCCCCEEEEEEEEEEEECCHHHHCCEEEECCE
YAMGLSETHGSITKGKKANLIITKPISSYYQIPYAFGSNLIEDVLIDGQII
EEECCCCCCCCCCCCCCCCEEEECCCHHHHCCHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MITLIKNIQELLQVRQTSISKVSGAEMAELPTIKNAFLVIKDDLIADFGSMENLPEIKAD
CCHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCEEEEEEHHHHHHHCCCCCCCCCCCC
SIINASGRVVLPAWCDSHTHIVYAGNREQEFVDRINGFTYEEIANRGGGILNSAKKLNET
CEECCCCCEEEEEECCCCCEEEEECCCHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHCCC
SEEEIYEQSKIRLEEVMRLGTGAVEIKSGYGLTVEGELKMLRVIKKLAENYPISIKATFL
HHHHHHHHHHHHHHHHHHHCCCEEEEECCCCEEEECHHHHHHHHHHHHCCCCEEEEEEEE
GAHAFPTHYKENKAGYIDEIITKMLPEIAQNKLADYVDVFCESGYFSVEETEKIMQAGID
ECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCC
FGLKPKIHVNQFNSIGGIQSGVKFNALSVDHLEIMNPEDIEALKGTETMPVALPSCSYFL
CCCCCCEEECCCCCCCCCCCCCEEEEEEECCEECCCCCHHHHHCCCCCCEEEECCCEEEE
SIPYTPAREMIKAGLPLALATDFNPGSTPSGNMNFVVATACIKMKMTPEEAINAATINGA
ECCCCCHHHHHHCCCCEEEEECCCCCCCCCCCCEEEEEEEEEEEECCHHHHCCEEEECCE
YAMGLSETHGSITKGKKANLIITKPISSYYQIPYAFGSNLIEDVLIDGQII
EEECCCCCCCCCCCCCCCCEEEECCCHHHHCCHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA