Click here to switch to the map view.

The map label for this gene is rnz [H]

Identifier: 146302270

GI number: 146302270

Start: 5489263

End: 5490168

Strand: Reverse

Name: rnz [H]

Synonym: Fjoh_4543

Alternate gene names: 146302270

Gene position: 5490168-5489263 (Counterclockwise)

Preceding gene: 146302271

Following gene: 146302269

Centisome position: 90.05

GC content: 34.0

Gene sequence:

>906_bases
TTGAAATTAACCATACTAGGCTGTTATGCCGCAACTCCCAGAACGCTTACTAACCCTACTTCGCAGGTTTTAGAAATCAA
GAACCGATTGTTTTTAATTGACTGCGGTGAAGGAACTCAGGTACAGCTTAGAAAAAACAAGATTAAGTTCTCAAAAATTA
ATCACATTTTTATTTCGCATCTTCATGGCGATCATTTATATGGATTAATAGGAACTATTTCGACTTTTTCTCTTTTGGGA
AGAACTACAGATTTACATATTTACGGTCCAAAAGGAATTAAGGAATTAATTCTTCTTCAATTAAAATTGACAGAATCCTG
GACGACATATGATTTGTTTTTTCACGAATTAGAGTCAAAAGAAAGCGAAGTTATTTTTGAAGATAAACGTGTTATCGTGA
GAACAATTCCGCTGAAACACCGTGTTTATACAAATGGATATCTTTTTCAGGAAAAACCAGATGAAAGAAAACTAAATGTT
GAAGCTGTTCAGAGTTATGATATTCACGTTGCTTATTATCAGAAAATAAAAAATGGAAGCGATATTACACTCGATAACGG
AACTGTAGTCGAAAACCACAAACTTACATTTGATCCGCCGCCTTCAAAAAGTTATGCTTTTTGTTCAGACACGGTTTATA
ATGAAGCCGTAATTCCAATTATCCAAAACACAGATGTTTTATACCACGAATCAACGTTTTTAGAATCTGAAGCGCCATTG
GCATTAAAAACTTTGCATTCAACAGCAAAAGAAGCAGCTGCTATTGCTTTAAAAGCTAATGTAAAACAATTAATTTTAGG
TCATTATTCAACACGTTATGACGGAATTGAACGTTTTAAGGAAGAAGCAGAAACGGTTTTTCCAAACGTGCTTTTGGCAG
ATGACGGTTTGAGTTTTGAGTTATAA

Upstream 100 bases:

>100_bases
TTTTAAAATTAGTTTAATTGTTTATTCGTTTAACTGTTTAATCGATTTGATTTAATTTTAACGATTAAACGATTTAACAC
ATAAACGAATAAACATAAAA

Downstream 100 bases:

>100_bases
TTTTTTAAGGTGCTAAGGTTCTGAGATACTAAGTTTCTAAGTTTTTACTCATCTGTAAATTGTCATCCTGACAAACCTGA
AACTTGAAACCTGAAACAAA

Product: ribonuclease Z

Products: NA

Alternate protein names: RNase Z; tRNA 3 endonuclease; tRNase Z [H]

Number of amino acids: Translated: 301; Mature: 301

Protein sequence:

>301_residues
MKLTILGCYAATPRTLTNPTSQVLEIKNRLFLIDCGEGTQVQLRKNKIKFSKINHIFISHLHGDHLYGLIGTISTFSLLG
RTTDLHIYGPKGIKELILLQLKLTESWTTYDLFFHELESKESEVIFEDKRVIVRTIPLKHRVYTNGYLFQEKPDERKLNV
EAVQSYDIHVAYYQKIKNGSDITLDNGTVVENHKLTFDPPPSKSYAFCSDTVYNEAVIPIIQNTDVLYHESTFLESEAPL
ALKTLHSTAKEAAAIALKANVKQLILGHYSTRYDGIERFKEEAETVFPNVLLADDGLSFEL

Sequences:

>Translated_301_residues
MKLTILGCYAATPRTLTNPTSQVLEIKNRLFLIDCGEGTQVQLRKNKIKFSKINHIFISHLHGDHLYGLIGTISTFSLLG
RTTDLHIYGPKGIKELILLQLKLTESWTTYDLFFHELESKESEVIFEDKRVIVRTIPLKHRVYTNGYLFQEKPDERKLNV
EAVQSYDIHVAYYQKIKNGSDITLDNGTVVENHKLTFDPPPSKSYAFCSDTVYNEAVIPIIQNTDVLYHESTFLESEAPL
ALKTLHSTAKEAAAIALKANVKQLILGHYSTRYDGIERFKEEAETVFPNVLLADDGLSFEL
>Mature_301_residues
MKLTILGCYAATPRTLTNPTSQVLEIKNRLFLIDCGEGTQVQLRKNKIKFSKINHIFISHLHGDHLYGLIGTISTFSLLG
RTTDLHIYGPKGIKELILLQLKLTESWTTYDLFFHELESKESEVIFEDKRVIVRTIPLKHRVYTNGYLFQEKPDERKLNV
EAVQSYDIHVAYYQKIKNGSDITLDNGTVVENHKLTFDPPPSKSYAFCSDTVYNEAVIPIIQNTDVLYHESTFLESEAPL
ALKTLHSTAKEAAAIALKANVKQLILGHYSTRYDGIERFKEEAETVFPNVLLADDGLSFEL

Specific function: Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA [H]

COG id: COG1234

COG function: function code R; Metal-dependent hydrolases of the beta-lactamase superfamily III

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNase Z family [H]

Homologues:

Organism=Homo sapiens, GI8922122, Length=351, Percent_Identity=29.6296296296296, Blast_Score=150, Evalue=1e-36,
Organism=Escherichia coli, GI87082078, Length=302, Percent_Identity=35.0993377483444, Blast_Score=179, Evalue=2e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279
- InterPro:   IPR013471 [H]

Pfam domain/function: PF00753 Lactamase_B [H]

EC number: =3.1.26.11 [H]

Molecular weight: Translated: 34223; Mature: 34223

Theoretical pI: Translated: 6.65; Mature: 6.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
0.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLTILGCYAATPRTLTNPTSQVLEIKNRLFLIDCGEGTQVQLRKNKIKFSKINHIFISH
CEEEEEEEECCCCCCCCCCHHHHHHHCCCEEEEECCCCCEEEEEECEEEEEEECEEEEEE
LHGDHLYGLIGTISTFSLLGRTTDLHIYGPKGIKELILLQLKLTESWTTYDLFFHELESK
CCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCHHEEEEEEEEECCCCCHHHHHHHHHCCC
ESEVIFEDKRVIVRTIPLKHRVYTNGYLFQEKPDERKLNVEAVQSYDIHVAYYQKIKNGS
CCCEEEECCEEEEEECCCCEEEEECCEEECCCCCCCCCCEEEEEEEEEEEEEEEHHCCCC
DITLDNGTVVENHKLTFDPPPSKSYAFCSDTVYNEAVIPIIQNTDVLYHESTFLESEAPL
EEEECCCEEEECCEEEECCCCCCCEEEECCCCCCCEEEEEEECCEEEEECCEECCCCCCH
ALKTLHSTAKEAAAIALKANVKQLILGHYSTRYDGIERFKEEAETVFPNVLLADDGLSFE
HHHHHHHHHHHHEEEEECCCHHHHHHHCCCHHHHHHHHHHHHHHHHCCEEEEECCCCEEC
L
C
>Mature Secondary Structure
MKLTILGCYAATPRTLTNPTSQVLEIKNRLFLIDCGEGTQVQLRKNKIKFSKINHIFISH
CEEEEEEEECCCCCCCCCCHHHHHHHCCCEEEEECCCCCEEEEEECEEEEEEECEEEEEE
LHGDHLYGLIGTISTFSLLGRTTDLHIYGPKGIKELILLQLKLTESWTTYDLFFHELESK
CCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCHHEEEEEEEEECCCCCHHHHHHHHHCCC
ESEVIFEDKRVIVRTIPLKHRVYTNGYLFQEKPDERKLNVEAVQSYDIHVAYYQKIKNGS
CCCEEEECCEEEEEECCCCEEEEECCEEECCCCCCCCCCEEEEEEEEEEEEEEEHHCCCC
DITLDNGTVVENHKLTFDPPPSKSYAFCSDTVYNEAVIPIIQNTDVLYHESTFLESEAPL
EEEECCCEEEECCEEEECCCCCCCEEEECCCCCCCEEEEEEECCEEEEECCEECCCCCCH
ALKTLHSTAKEAAAIALKANVKQLILGHYSTRYDGIERFKEEAETVFPNVLLADDGLSFE
HHHHHHHHHHHHEEEEECCCHHHHHHHCCCHHHHHHHHHHHHHHHHCCEEEEECCCCEEC
L
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA