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The map label for this gene is yraA [H]

Identifier: 146302026

GI number: 146302026

Start: 5182819

End: 5183367

Strand: Reverse

Name: yraA [H]

Synonym: Fjoh_4290

Alternate gene names: 146302026

Gene position: 5183367-5182819 (Counterclockwise)

Preceding gene: 146302033

Following gene: 146302025

Centisome position: 85.02

GC content: 37.52

Gene sequence:

>549_bases
ATGAAAAAGAATATAGCAATATTAGCCACAAACGGTTTTGAAGAATCAGAATTAGCATCACCTAAAGCCTATCTTGAAGA
GCAAGGCTGGAATGCAGATATCGTCAGTTTGAAATCTGGAACTATCAAATCTTGGAAAGACGGAAATTGGAGCAAAGAAT
ATAATGTTGATGTCGTATTAGATCAGGCAAATGAAGCAGATTACGATGCTTTGGTTCTGCCGGGAGGAGTTATAAACCCT
GATTTATTGAGAAGAGAAGAAACTGCAGTAAATTTTGTACGTTCTTTTTTTGAAAGTAAAAAACCTGTAGCCGCTATTTG
TCACGGACCTCAAATTCTGGTAGATGCCGATGTTTTAGAAGGTCGAAAAGTAACTTCGTTCTTTTCTGTTAAAAACGATT
TGAAAAATGCCGGAGCACAATGGGAAGATTCAGAAGTTGTCGTAGACAATGGATTAGTGACCAGCCGAAACCCAAATGAT
TTACCCGCTTTTAATAAAAAAATGGTGGAAGAAATTAAAGAGGGAATACACGAACGCCAGAGAGTCTAA

Upstream 100 bases:

>100_bases
TTATTAAAGAAAGCTTTAACAGGAACTGTTTCTGCTGGCTGTTTGAAATAACTAATTTTAACTTAAATCAAAATTAATAA
CGTTTTAAACATTTAAAATC

Downstream 100 bases:

>100_bases
AAAAGAATTTTCTATTTAGATTTGTCAAATTATAAAAATGCAGGATCATATTTTGGTTCTGCATTTTTTTGTGGTTTTTA
AATCTGCTAATAAAGTTCCG

Product: PfpI family intracellular peptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 182; Mature: 182

Protein sequence:

>182_residues
MKKNIAILATNGFEESELASPKAYLEEQGWNADIVSLKSGTIKSWKDGNWSKEYNVDVVLDQANEADYDALVLPGGVINP
DLLRREETAVNFVRSFFESKKPVAAICHGPQILVDADVLEGRKVTSFFSVKNDLKNAGAQWEDSEVVVDNGLVTSRNPND
LPAFNKKMVEEIKEGIHERQRV

Sequences:

>Translated_182_residues
MKKNIAILATNGFEESELASPKAYLEEQGWNADIVSLKSGTIKSWKDGNWSKEYNVDVVLDQANEADYDALVLPGGVINP
DLLRREETAVNFVRSFFESKKPVAAICHGPQILVDADVLEGRKVTSFFSVKNDLKNAGAQWEDSEVVVDNGLVTSRNPND
LPAFNKKMVEEIKEGIHERQRV
>Mature_182_residues
MKKNIAILATNGFEESELASPKAYLEEQGWNADIVSLKSGTIKSWKDGNWSKEYNVDVVLDQANEADYDALVLPGGVINP
DLLRREETAVNFVRSFFESKKPVAAICHGPQILVDADVLEGRKVTSFFSVKNDLKNAGAQWEDSEVVVDNGLVTSRNPND
LPAFNKKMVEEIKEGIHERQRV

Specific function: Functions in the protection against aldehyde-stress, possibly by degrading damaged proteins [H]

COG id: COG0693

COG function: function code R; Putative intracellular protease/amidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PfpI endopeptidase domain [H]

Homologues:

Organism=Escherichia coli, GI87082219, Length=170, Percent_Identity=45.8823529411765, Blast_Score=147, Evalue=6e-37,
Organism=Drosophila melanogaster, GI28571932, Length=181, Percent_Identity=29.2817679558011, Blast_Score=72, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006286
- InterPro:   IPR002818 [H]

Pfam domain/function: PF01965 DJ-1_PfpI [H]

EC number: NA

Molecular weight: Translated: 20278; Mature: 20278

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKNIAILATNGFEESELASPKAYLEEQGWNADIVSLKSGTIKSWKDGNWSKEYNVDVVL
CCCCEEEEEECCCCHHHHCCCHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCCEEEEE
DQANEADYDALVLPGGVINPDLLRREETAVNFVRSFFESKKPVAAICHGPQILVDADVLE
ECCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCEEEEECCHHC
GRKVTSFFSVKNDLKNAGAQWEDSEVVVDNGLVTSRNPNDLPAFNKKMVEEIKEGIHERQ
CCCHHHHHHHHHHHHHCCCCCCCCEEEEECCEEECCCCCCCCHHHHHHHHHHHHHHHHHH
RV
CC
>Mature Secondary Structure
MKKNIAILATNGFEESELASPKAYLEEQGWNADIVSLKSGTIKSWKDGNWSKEYNVDVVL
CCCCEEEEEECCCCHHHHCCCHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCCEEEEE
DQANEADYDALVLPGGVINPDLLRREETAVNFVRSFFESKKPVAAICHGPQILVDADVLE
ECCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCEEEEECCHHC
GRKVTSFFSVKNDLKNAGAQWEDSEVVVDNGLVTSRNPNDLPAFNKKMVEEIKEGIHERQ
CCCHHHHHHHHHHHHHCCCCCCCCEEEEECCEEECCCCCCCCHHHHHHHHHHHHHHHHHH
RV
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9141695; 9384377; 10568751 [H]