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The map label for this gene is nrdD [C]

Identifier: 146301794

GI number: 146301794

Start: 4843449

End: 4845572

Strand: Direct

Name: nrdD [C]

Synonym: Fjoh_4058

Alternate gene names: 146301794

Gene position: 4843449-4845572 (Clockwise)

Preceding gene: 146301793

Following gene: 146301795

Centisome position: 79.44

GC content: 37.66

Gene sequence:

>2124_bases
ATGGAAAAATATGTGATCAAACGAAACGGAGATTATAAACCTTTTGAAGCTTATAAAATTCAGGATGCCATCCAGAAAGC
TTTTAAAAGCGTCAATCTGCCGATGGATAAAAAAATTCTGAAAATCGTTCTAAACGGACTCGAACCAAAATATTCGTGGC
CTGTTGAGGAGATTCAGGATAGTATAGAACGTGTGCTTTTTGAAAACGGTTATTTTAAAACCATGCGTTCCTTTATTATC
TATCGACATACCCGAAAACTCCAGAGAGAACATATTAACGGCCTAAACGACGATACAACGTATGTAGACAGCACACAAAC
GGTTGAAGAATACATCAATCAATCTGACTGGCGTATTAATGCCAATGCTAATACATCGTACTCAAATGCCGGTTTAGTAA
GCAATACTGCCGGTAAAATTATTGCCAATTACTGGCTCGATAAAATTTATACTAAAGAAGAAGGCGCCTCACACCGAAAC
GGAGATATTCACATTCATGATCTGGACTGCCTTACGGGATATTGTGCCGGATGGAGCTTACGTGTTCTTTTAAACGAAGG
TTTCAACGGCGTTCGCGGCCGTGTAGAAAGCAGACCTCCTTCGCATTTTAGGGAAGCTTTGGGGCAGATGGCTAATTTTC
TGGGAATTCTGCAAAGCGAATGGGCAGGCGCTCAGGCTTTCAGTTCTTTTGATACATATCTAGCTCCTTATGTTTTCAAA
GACCAGCTTTCTTACGATCAGGTTTTAAAAGGCATTAGAAGTTTTGTTTACAACCTCAATGTTCCGGCAAGATGGGGACA
ATCTCCTTTTACGAATATAACCTTAGACTGGAATGTGCCAAACGATCTTAAAGAACAGATTCCGACAAGAAATGACGAAC
ATTTGTTTCTGTATTCAGATGATCCCGAACTGGTTTATAAAGCTAAAAAAAGAGGGGTTAATAAACTGACTGATTTAAAA
TATGCCGATTTCCAAAACGAAATGAACCTAATCAATAAGGCATATTATACCATCATGACAGAAGGCGACACAAATGGACA
GCCTTTTACCTTCCCTATTCCAACTGTAAATATTACGGAGGATTTTGACTGGGAAGGCGAAAATGTCGATTTATTATTTG
AAAACACAGCCAAGATAGGGTCTTCTTATTTTCAGAATTTTATTGGAAGCCAGTATATTTTAAATGAAAATGGAAATAAA
ATCGAAAATCCAGAAGCTTACAAACCCAACGCTGTCAGAAGTATGTGCTGTCGTTTACAGCTCGATCTGCGCGAATTATT
AAAACGAGGAAATGGTCTTTTTGGAAGTGCAGAAATGACAGGCAGTATTGGTGTTGTAACCATTAATATGGCCCGTTTGG
GATATCTGTATAAAGGAAATATTATAAACTTATTTGATCATTTAAATGATCTGCTTCAGATTGCCAAATCGACTTTGGAG
AAAAAGAGAATCTTTATTCAAAAAATGTACGACCGTGGTTTGTATCCTTATACACAGCGCTATTTGTCACATTTTAGAAA
CCACTTTTCCACCATTGGCGTAAACGGAATGAATGAAATGGTACTCAATTTTACTGATGGAAAACAAGATATTACAACAA
GTTCAGGAATTCATTTTGCTGAAGAAATTTTAGATTACATCCGTTCGAGAATGAAAGAATTTCAGGCAGAAACCGGAAAT
TTATACAATCTGGAAGCTACTCCCGCAGAAGGAACTACCTATCGTTTTGCCAAAGAAGATAAAAAACGTTTTCCAGAAAT
CCTGCAGGCCGGACATGGAGAAAATATTTATTACACAAACAGTTCGCAGATTCCGGTAGATCATACAGATGATCCGTTTG
AAGCTTTACTGCTTCAGGACGCTTTACAATGTAAATATACCGGCGGTACCGTTCTGCATTTGTATATGAGAGAAAAAATA
AGCAGTCCTGCTGCGTGTAAAAACTTCGTAAAAAAAGTGCTGACCAATTTTAAACTGCCTTATATAACAGTAACGCCAGT
TTTCAGTATCTGCCCAATTCATGGATACCTGGACGGTGAGCATGAATACTGCCCAAAATGCGATGAAATATTGTTAAATG
AAAATAACCAAAAAGCTATACTATATGAAAACACTGTATCATAA

Upstream 100 bases:

>100_bases
GAATCTGCACAAGCATATTCACATGGAAAACAATATACTGTTTCCTAAAGCAATTATGCTTGAAAAAAACTTTGAGCAAG
TGCCTTAAATTATAAATATC

Downstream 100 bases:

>100_bases
AATTCCTGAAAAACTAAATGCTAAAAGAAGCAAATGTTTAGTATACACAAGAGTAATGGGCTATCACAGGCCAGTAGAAA
GTTTTAACATTGGAAAAAAA

Product: anaerobic ribonucleoside triphosphate reductase

Products: ribonucleoside triphosphate; thioredoxin

Alternate protein names: NA

Number of amino acids: Translated: 707; Mature: 707

Protein sequence:

>707_residues
MEKYVIKRNGDYKPFEAYKIQDAIQKAFKSVNLPMDKKILKIVLNGLEPKYSWPVEEIQDSIERVLFENGYFKTMRSFII
YRHTRKLQREHINGLNDDTTYVDSTQTVEEYINQSDWRINANANTSYSNAGLVSNTAGKIIANYWLDKIYTKEEGASHRN
GDIHIHDLDCLTGYCAGWSLRVLLNEGFNGVRGRVESRPPSHFREALGQMANFLGILQSEWAGAQAFSSFDTYLAPYVFK
DQLSYDQVLKGIRSFVYNLNVPARWGQSPFTNITLDWNVPNDLKEQIPTRNDEHLFLYSDDPELVYKAKKRGVNKLTDLK
YADFQNEMNLINKAYYTIMTEGDTNGQPFTFPIPTVNITEDFDWEGENVDLLFENTAKIGSSYFQNFIGSQYILNENGNK
IENPEAYKPNAVRSMCCRLQLDLRELLKRGNGLFGSAEMTGSIGVVTINMARLGYLYKGNIINLFDHLNDLLQIAKSTLE
KKRIFIQKMYDRGLYPYTQRYLSHFRNHFSTIGVNGMNEMVLNFTDGKQDITTSSGIHFAEEILDYIRSRMKEFQAETGN
LYNLEATPAEGTTYRFAKEDKKRFPEILQAGHGENIYYTNSSQIPVDHTDDPFEALLLQDALQCKYTGGTVLHLYMREKI
SSPAACKNFVKKVLTNFKLPYITVTPVFSICPIHGYLDGEHEYCPKCDEILLNENNQKAILYENTVS

Sequences:

>Translated_707_residues
MEKYVIKRNGDYKPFEAYKIQDAIQKAFKSVNLPMDKKILKIVLNGLEPKYSWPVEEIQDSIERVLFENGYFKTMRSFII
YRHTRKLQREHINGLNDDTTYVDSTQTVEEYINQSDWRINANANTSYSNAGLVSNTAGKIIANYWLDKIYTKEEGASHRN
GDIHIHDLDCLTGYCAGWSLRVLLNEGFNGVRGRVESRPPSHFREALGQMANFLGILQSEWAGAQAFSSFDTYLAPYVFK
DQLSYDQVLKGIRSFVYNLNVPARWGQSPFTNITLDWNVPNDLKEQIPTRNDEHLFLYSDDPELVYKAKKRGVNKLTDLK
YADFQNEMNLINKAYYTIMTEGDTNGQPFTFPIPTVNITEDFDWEGENVDLLFENTAKIGSSYFQNFIGSQYILNENGNK
IENPEAYKPNAVRSMCCRLQLDLRELLKRGNGLFGSAEMTGSIGVVTINMARLGYLYKGNIINLFDHLNDLLQIAKSTLE
KKRIFIQKMYDRGLYPYTQRYLSHFRNHFSTIGVNGMNEMVLNFTDGKQDITTSSGIHFAEEILDYIRSRMKEFQAETGN
LYNLEATPAEGTTYRFAKEDKKRFPEILQAGHGENIYYTNSSQIPVDHTDDPFEALLLQDALQCKYTGGTVLHLYMREKI
SSPAACKNFVKKVLTNFKLPYITVTPVFSICPIHGYLDGEHEYCPKCDEILLNENNQKAILYENTVS
>Mature_707_residues
MEKYVIKRNGDYKPFEAYKIQDAIQKAFKSVNLPMDKKILKIVLNGLEPKYSWPVEEIQDSIERVLFENGYFKTMRSFII
YRHTRKLQREHINGLNDDTTYVDSTQTVEEYINQSDWRINANANTSYSNAGLVSNTAGKIIANYWLDKIYTKEEGASHRN
GDIHIHDLDCLTGYCAGWSLRVLLNEGFNGVRGRVESRPPSHFREALGQMANFLGILQSEWAGAQAFSSFDTYLAPYVFK
DQLSYDQVLKGIRSFVYNLNVPARWGQSPFTNITLDWNVPNDLKEQIPTRNDEHLFLYSDDPELVYKAKKRGVNKLTDLK
YADFQNEMNLINKAYYTIMTEGDTNGQPFTFPIPTVNITEDFDWEGENVDLLFENTAKIGSSYFQNFIGSQYILNENGNK
IENPEAYKPNAVRSMCCRLQLDLRELLKRGNGLFGSAEMTGSIGVVTINMARLGYLYKGNIINLFDHLNDLLQIAKSTLE
KKRIFIQKMYDRGLYPYTQRYLSHFRNHFSTIGVNGMNEMVLNFTDGKQDITTSSGIHFAEEILDYIRSRMKEFQAETGN
LYNLEATPAEGTTYRFAKEDKKRFPEILQAGHGENIYYTNSSQIPVDHTDDPFEALLLQDALQCKYTGGTVLHLYMREKI
SSPAACKNFVKKVLTNFKLPYITVTPVFSICPIHGYLDGEHEYCPKCDEILLNENNQKAILYENTVS

Specific function: Unknown

COG id: COG1328

COG function: function code F; Oxygen-sensitive ribonucleoside-triphosphate reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 DOD-type homing endonuclease domains [H]

Homologues:

Organism=Escherichia coli, GI1790686, Length=247, Percent_Identity=26.7206477732794, Blast_Score=85, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005144
- InterPro:   IPR003586
- InterPro:   IPR003587
- InterPro:   IPR007869
- InterPro:   IPR006142
- InterPro:   IPR004042
- InterPro:   IPR006141
- InterPro:   IPR012833 [H]

Pfam domain/function: PF03477 ATP-cone; PF05204 Hom_end [H]

EC number: 1.17.4.2

Molecular weight: Translated: 81273; Mature: 81273

Theoretical pI: Translated: 6.22; Mature: 6.22

Prosite motif: PS51161 ATP_CONE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKYVIKRNGDYKPFEAYKIQDAIQKAFKSVNLPMDKKILKIVLNGLEPKYSWPVEEIQD
CCCEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCHHHHHH
SIERVLFENGYFKTMRSFIIYRHTRKLQREHINGLNDDTTYVDSTQTVEEYINQSDWRIN
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCCCCEEEE
ANANTSYSNAGLVSNTAGKIIANYWLDKIYTKEEGASHRNGDIHIHDLDCLTGYCAGWSL
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEHHHHHHHHCCCEE
RVLLNEGFNGVRGRVESRPPSHFREALGQMANFLGILQSEWAGAQAFSSFDTYLAPYVFK
EEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHH
DQLSYDQVLKGIRSFVYNLNVPARWGQSPFTNITLDWNVPNDLKEQIPTRNDEHLFLYSD
HCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCHHHHHHCCCCCCCEEEEECC
DPELVYKAKKRGVNKLTDLKYADFQNEMNLINKAYYTIMTEGDTNGQPFTFPIPTVNITE
CHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHHHEEEEEEECCCCCCCCEEECCCEEECCC
DFDWEGENVDLLFENTAKIGSSYFQNFIGSQYILNENGNKIENPEAYKPNAVRSMCCRLQ
CCCCCCCCEEEEECCHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHH
LDLRELLKRGNGLFGSAEMTGSIGVVTINMARLGYLYKGNIINLFDHLNDLLQIAKSTLE
HHHHHHHHHCCCCEECCCCCCCEEEEEEEHHHHCEEEECCCHHHHHHHHHHHHHHHHHHH
KKRIFIQKMYDRGLYPYTQRYLSHFRNHFSTIGVNGMNEMVLNFTDGKQDITTSSGIHFA
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCCHHHH
EEILDYIRSRMKEFQAETGNLYNLEATPAEGTTYRFAKEDKKRFPEILQAGHGENIYYTN
HHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCEEEHHHHHHHHHHHHHHCCCCCEEEEEC
SSQIPVDHTDDPFEALLLQDALQCKYTGGTVLHLYMREKISSPAACKNFVKKVLTNFKLP
CCCCCCCCCCCHHHHHHHHHHHHEEECCCCEEEEEEHHHCCCCHHHHHHHHHHHHCCCCC
YITVTPVFSICPIHGYLDGEHEYCPKCDEILLNENNQKAILYENTVS
EEEECCHHHHCCCCCEECCCCCCCCCHHHHHCCCCCCEEEEEECCCC
>Mature Secondary Structure
MEKYVIKRNGDYKPFEAYKIQDAIQKAFKSVNLPMDKKILKIVLNGLEPKYSWPVEEIQD
CCCEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCHHHHHH
SIERVLFENGYFKTMRSFIIYRHTRKLQREHINGLNDDTTYVDSTQTVEEYINQSDWRIN
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCCCCEEEE
ANANTSYSNAGLVSNTAGKIIANYWLDKIYTKEEGASHRNGDIHIHDLDCLTGYCAGWSL
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEHHHHHHHHCCCEE
RVLLNEGFNGVRGRVESRPPSHFREALGQMANFLGILQSEWAGAQAFSSFDTYLAPYVFK
EEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHH
DQLSYDQVLKGIRSFVYNLNVPARWGQSPFTNITLDWNVPNDLKEQIPTRNDEHLFLYSD
HCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCHHHHHHCCCCCCCEEEEECC
DPELVYKAKKRGVNKLTDLKYADFQNEMNLINKAYYTIMTEGDTNGQPFTFPIPTVNITE
CHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHHHEEEEEEECCCCCCCCEEECCCEEECCC
DFDWEGENVDLLFENTAKIGSSYFQNFIGSQYILNENGNKIENPEAYKPNAVRSMCCRLQ
CCCCCCCCEEEEECCHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHH
LDLRELLKRGNGLFGSAEMTGSIGVVTINMARLGYLYKGNIINLFDHLNDLLQIAKSTLE
HHHHHHHHHCCCCEECCCCCCCEEEEEEEHHHHCEEEECCCHHHHHHHHHHHHHHHHHHH
KKRIFIQKMYDRGLYPYTQRYLSHFRNHFSTIGVNGMNEMVLNFTDGKQDITTSSGIHFA
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCCHHHH
EEILDYIRSRMKEFQAETGNLYNLEATPAEGTTYRFAKEDKKRFPEILQAGHGENIYYTN
HHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCEEEHHHHHHHHHHHHHHCCCCCEEEEEC
SSQIPVDHTDDPFEALLLQDALQCKYTGGTVLHLYMREKISSPAACKNFVKKVLTNFKLP
CCCCCCCCCCCHHHHHHHHHHHHEEECCCCEEEEEEHHHCCCCHHHHHHHHHHHHCCCCC
YITVTPVFSICPIHGYLDGEHEYCPKCDEILLNENNQKAILYENTVS
EEEECCHHHHCCCCCEECCCCCCCCCHHHHHCCCCCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Ca2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2'-deoxyribonucleoside triphosphate; thioredoxin disulfide; H2O

Specific reaction: 2'-deoxyribonucleoside triphosphate + thioredoxin disulfide + H2O = ribonucleoside triphosphate + thioredoxin

General reaction: Redox reaction [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]