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The map label for this gene is xerD [H]

Identifier: 146301359

GI number: 146301359

Start: 4313729

End: 4314646

Strand: Reverse

Name: xerD [H]

Synonym: Fjoh_3617

Alternate gene names: 146301359

Gene position: 4314646-4313729 (Counterclockwise)

Preceding gene: 146301360

Following gene: 146301358

Centisome position: 70.77

GC content: 41.5

Gene sequence:

>918_bases
ATGAAAAAAAATATACAGTCTAAGGACTTTCAAAGGCTCGCAGGGGCATTTGACAAATTTGTGAAAGTCCGGAATTACAA
ACAGGGAAGATCAAATCTGTACAGAAACATCATAACCGAATTTCTGATCTGGCTTGAACAGGCAGGAGTCAGCAGGATGC
AGAATGTGACTTCAAAAGAATCCGTGAAGTATCTGGAATACCTCACAGCAAGACCAAAGAAAAGAGGGAACGGCGTACTG
GCGGAAAAGACAATCAAACTGCATCTGTTTGTACAGGGGCTTTTTCAGGTTTACCTTCTTGAAAACAAAGAAATCCAGAA
TATCTATTATATCCCTTCCGTTTCGGGAGAAACCCAGAAGCCCAGAAATATCCTCACTATAGAAGAAATAAAACTGGTCT
ACCAGTATGCAGAGAATGAAATGGAAAAAGCCCTGCTGTCTATTGCCTATGGATGCGGACTGAGAAGATCAGAAATTGCA
AACCTTGACTTAAAAGATGTAAGCCTTATCAAAGGAATGATTGTAGTGAGGCAGGGAAAAGGAAACAAAAGACGCGAAGT
GCCTATGAGCGATACGGTTTTGGAATACTTAAAAAAATACATCAGGAATGAGAGACCTGAAAGGTTGTCAGGAAGAAACC
AGAATGAGGAAGCATTCTTCATTAACAGCAGAGGCAGAAGATCAACAGGCGAAAACCTTAATGAGATCCTCAGCAAAATG
ATCGAGCAGACTGGAAAATTCGAGCTTGTCCAGAAAGAAATAACGCTCCACTGCCTTCGACACAGCATTGCGTTCCATCT
GGCAGAGAATAATGCAGGGATTGACTTTATACGCAGTTTTTTGGGGCATACCCAGATCAATACCACATACATCTATGCGG
TGCAGAACAAAAAACGCAAGCCAGTCGTAAACTTCTAA

Upstream 100 bases:

>100_bases
TACTGGCTATACGATACTGGCGTTCCGCGTTCCAGAAGGTGCGCAAGCACAGGCTTTCAAATAGCAGAGAATAAAACACA
ATAATTAAAAGAAAAATACA

Downstream 100 bases:

>100_bases
AAACGAACCAATGGAAAATAAAAAACCTGATCTTGAAAAGTACCTAAAAGGAATACTCTCCAAATCGACAGCAGAAAGCT
ACATGTACACCATCAATCAT

Product: phage integrase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 305; Mature: 305

Protein sequence:

>305_residues
MKKNIQSKDFQRLAGAFDKFVKVRNYKQGRSNLYRNIITEFLIWLEQAGVSRMQNVTSKESVKYLEYLTARPKKRGNGVL
AEKTIKLHLFVQGLFQVYLLENKEIQNIYYIPSVSGETQKPRNILTIEEIKLVYQYAENEMEKALLSIAYGCGLRRSEIA
NLDLKDVSLIKGMIVVRQGKGNKRREVPMSDTVLEYLKKYIRNERPERLSGRNQNEEAFFINSRGRRSTGENLNEILSKM
IEQTGKFELVQKEITLHCLRHSIAFHLAENNAGIDFIRSFLGHTQINTTYIYAVQNKKRKPVVNF

Sequences:

>Translated_305_residues
MKKNIQSKDFQRLAGAFDKFVKVRNYKQGRSNLYRNIITEFLIWLEQAGVSRMQNVTSKESVKYLEYLTARPKKRGNGVL
AEKTIKLHLFVQGLFQVYLLENKEIQNIYYIPSVSGETQKPRNILTIEEIKLVYQYAENEMEKALLSIAYGCGLRRSEIA
NLDLKDVSLIKGMIVVRQGKGNKRREVPMSDTVLEYLKKYIRNERPERLSGRNQNEEAFFINSRGRRSTGENLNEILSKM
IEQTGKFELVQKEITLHCLRHSIAFHLAENNAGIDFIRSFLGHTQINTTYIYAVQNKKRKPVVNF
>Mature_305_residues
MKKNIQSKDFQRLAGAFDKFVKVRNYKQGRSNLYRNIITEFLIWLEQAGVSRMQNVTSKESVKYLEYLTARPKKRGNGVL
AEKTIKLHLFVQGLFQVYLLENKEIQNIYYIPSVSGETQKPRNILTIEEIKLVYQYAENEMEKALLSIAYGCGLRRSEIA
NLDLKDVSLIKGMIVVRQGKGNKRREVPMSDTVLEYLKKYIRNERPERLSGRNQNEEAFFINSRGRRSTGENLNEILSKM
IEQTGKFELVQKEITLHCLRHSIAFHLAENNAGIDFIRSFLGHTQINTTYIYAVQNKKRKPVVNF

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4974

COG function: function code L; Site-specific recombinase XerD

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789261, Length=291, Percent_Identity=26.1168384879725, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1790244, Length=151, Percent_Identity=29.8013245033113, Blast_Score=77, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011932 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 35492; Mature: 35492

Theoretical pI: Translated: 10.33; Mature: 10.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKNIQSKDFQRLAGAFDKFVKVRNYKQGRSNLYRNIITEFLIWLEQAGVSRMQNVTSKE
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SVKYLEYLTARPKKRGNGVLAEKTIKLHLFVQGLFQVYLLENKEIQNIYYIPSVSGETQK
HHHHHHHHHCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCC
PRNILTIEEIKLVYQYAENEMEKALLSIAYGCGLRRSEIANLDLKDVSLIKGMIVVRQGK
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCHHHHHHHHHEEEEECCC
GNKRREVPMSDTVLEYLKKYIRNERPERLSGRNQNEEAFFINSRGRRSTGENLNEILSKM
CCCCCCCCCHHHHHHHHHHHHHCCCCCHHCCCCCCCCEEEEECCCCCCCCCCHHHHHHHH
IEQTGKFELVQKEITLHCLRHSIAFHLAENNAGIDFIRSFLGHTQINTTYIYAVQNKKRK
HHHCCCHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHCCCCCCEEEEEEEECCCCC
PVVNF
CCCCC
>Mature Secondary Structure
MKKNIQSKDFQRLAGAFDKFVKVRNYKQGRSNLYRNIITEFLIWLEQAGVSRMQNVTSKE
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SVKYLEYLTARPKKRGNGVLAEKTIKLHLFVQGLFQVYLLENKEIQNIYYIPSVSGETQK
HHHHHHHHHCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCC
PRNILTIEEIKLVYQYAENEMEKALLSIAYGCGLRRSEIANLDLKDVSLIKGMIVVRQGK
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCHHHHHHHHHEEEEECCC
GNKRREVPMSDTVLEYLKKYIRNERPERLSGRNQNEEAFFINSRGRRSTGENLNEILSKM
CCCCCCCCCHHHHHHHHHHHHHCCCCCHHCCCCCCCCEEEEECCCCCCCCCCHHHHHHHH
IEQTGKFELVQKEITLHCLRHSIAFHLAENNAGIDFIRSFLGHTQINTTYIYAVQNKKRK
HHHCCCHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHCCCCCCEEEEEEEECCCCC
PVVNF
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12235376 [H]