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The map label for this gene is clpB [H]

Identifier: 146301164

GI number: 146301164

Start: 4087674

End: 4090277

Strand: Reverse

Name: clpB [H]

Synonym: Fjoh_3422

Alternate gene names: 146301164

Gene position: 4090277-4087674 (Counterclockwise)

Preceding gene: 146301167

Following gene: 146301163

Centisome position: 67.09

GC content: 36.83

Gene sequence:

>2604_bases
ATGAATATAAACAAGTTTACTATTAAATCGCAGGAAGCCATACAGTTGTCTCAGCAATTAGCACAACGAAACGGCCAGCA
GCAAATTGAAAATGAACACATTTTCAAAGCTATTTTTGAAGTTGATGAAAACGTTGCGCCATTCATTTTGAAGAAATTAA
ATGTAAATGTGCCTTTGTTTTTACAAATTTTAGACAGTACAATTCAGAGTTTTCCAAAAGTTTCCGGAGGCGATGTTATG
CTTTCGAGAGATGCAAATAAAGCTTTGAACGAAGCAGAAATTATTGCACAAAAAATGAACGACGAATACGTTTCGATCGA
GCATTTAATCTTGGCTATTTTTGATTCAAAAAGTAAAGTTTCTCAAATTTTAAAAGATCAGGGAGTTACAGGAAAAGGTC
TGAAAGCAGCAATCGAAGAACTTCGTAAAGGAGAGAGAGTAACTTCTGCTTCTGCCGAAGAAACCTATAATTCATTAAAT
AAATACGCTAAAAATCTAAACGAATTAGCACGTACAGGAAAATTAGATCCGGTTATTGGCCGTGATGAAGAAATTCGTCG
TGTATTACAAATTTTAACTCGTCGAACTAAAAACAACCCAATGCTTATTGGTGAACCCGGAGTTGGTAAAACCGCTATTG
CCGAAGGTTTAGCACATAGAATTGTAGATGGAGATGTTCCTGAAAACCTGAAAGATAAAATCGTTTTCTCTTTAGATATG
GGAGCTTTGATTGCCGGAGCAAAATATAAAGGAGAATTTGAAGAACGTTTAAAATCGGTTGTAAAAGAAGTTACAGCCGC
AGAAGGTGATATCGTATTGTTTATTGATGAAATTCACACGCTTGTAGGTGCAGGTGGAGGAGAAGGCGCAATGGATGCGG
CTAATATCCTGAAACCAGCTTTGGCGCGTGGAGAATTAAGAGCAATTGGTGCTACAACCTTAGACGAATATCAAAAGTAT
TTTGAAAAAGATAAAGCGCTTGAAAGACGTTTTCAAAAAGTATTAATCGATGAACCAGATACTGAAAGTGCTATTTCAAT
TTTACGTGGTATCAAAGAAAAATACGAAACGCATCATAAAGTTCAGATTAAAGACGAAGCAATTATTGCAGCTGTTGAAC
TTTCGCAAAGATATATTACCAATCGTTTTTTACCAGATAAAGCGATTGACTTAATGGACGAAGCTGCTTCTAAACTTCGT
ATGGAAATCAATTCAAAACCTGAGGAATTAGACGTTTTGGATCGTAAAATCATGCAGCTTGAAATTGAAATCGAAGCGAT
TAAACGTGAAAAAGAAGAAAGTAAGCTGAAAATTTTAGGTATGGAATTGGCCAACCTGAAAGAAGAGCGAAACGAGATCT
ATGCAAAATGGAAACAGGAAAAAGATATCGTTGACGGAATTCAGGCTGTAAAACACGAAATCGAAGACTTTAAATACGAA
GCAGAACGCGCAGAACGTGATGGTGATTATGGAAAAGTAGCTGAAATTCGTTATGGTAAAATAAAAGAAGCACAAGAACG
TCAGGAAAATTTGCAAAAGCAGTTATTGGAATTTCAATCTGGTAATTCTTTAATAAAAGAAGAAGTTACAAGAGAAGATA
TTGCAGAAGTTGTAGCAAAATGGACTGGAATTCCAGTAACAAAAATGCTTCAGACAGAGAGAGAAAAACTATTGCATCTT
GAAGATGAATTACACAAACGTGTAGTTGGGCAGGAAGAAGCGATTGAAGCCGTGAGTGATGCCGTTCGCAGAAGCCGTGC
CGGTTTGCAGGATATGAAAAAACCTGTTGGTTCATTCCTGTTTTTAGGAACAACCGGAGTTGGTAAAACGGAGCTTGCAA
AAGCCTTAGCCGAATATCTTTTCGATGACGAAAATGCGATGACTCGTATCGATATGAGTGAATACCAGGAACGTCATAGT
GTAAGCCGTTTGGTTGGTGCGCCTCCAGGATATGTAGGTTATGATGAAGGAGGTCAGTTAACAGAAGCTGTTCGTAGAAA
ACCTTATTCTGTTGTACTTTTAGACGAGATCGAAAAAGCACATCCGGATACTTTCAATATTTTATTGCAGGTTCTGGACG
AAGGACGTTTAACAGACAATAAAGGACGTCTTGCCGATTTTAGAAATACGATTATTATTATGACTTCAAATATGGGAAGT
AATATTATTCAGGAGAAATTTGAAAACCTAAAAGGAAGCGTTGAGGCAGCAACTGAAGCCGCTAAAAACGAAGTTTTAGG
ATTATTAAAGCAAACTGTTCGTCCTGAGTTTATCAACCGTATCGATGAGATTGTAATGTTTACACCGCTTACTGTAGAAA
ATATTTCAAGAATTGTAAGTTTACAGTTAAAGAGTGTTACTAAAATGCTGGCTCTGCAAGGTATTACAATGGATGCGACT
CCAGAAGCGATTGCTTATCTGGCAGATAAAGGTTACGACCCTCATTTTGGAGCGAGACCTGTAAAACGTGTAGTTCAAAG
AGAAGTCTTAAACCAATTGTCAAAAGAAATTCTGGCAGGGAATATTACAACAGATAGTATTATCTTATTAGATGCTTTTG
ATGGCAATTTGGTTTTTAGAAACCAGACTGAAGAAGCTAAATAA

Upstream 100 bases:

>100_bases
GTACAAAGTTAGATTATTTGAGTCAAAAATGTATCTCAATAAATTGTAACTTTAATGTAATCGAATATTTCAAACAAAAA
ATCAATCAAATCGAAAAAAT

Downstream 100 bases:

>100_bases
TTAAAGAGATGCACAGAAGGTGCGTCGTCAATGATAAGAAAAACACTAGTAGAAATGCTGGTGTTTTTTGTTTATCAGAT
TATTATCTTATTTGTAAAAT

Product: ATPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 867; Mature: 867

Protein sequence:

>867_residues
MNINKFTIKSQEAIQLSQQLAQRNGQQQIENEHIFKAIFEVDENVAPFILKKLNVNVPLFLQILDSTIQSFPKVSGGDVM
LSRDANKALNEAEIIAQKMNDEYVSIEHLILAIFDSKSKVSQILKDQGVTGKGLKAAIEELRKGERVTSASAEETYNSLN
KYAKNLNELARTGKLDPVIGRDEEIRRVLQILTRRTKNNPMLIGEPGVGKTAIAEGLAHRIVDGDVPENLKDKIVFSLDM
GALIAGAKYKGEFEERLKSVVKEVTAAEGDIVLFIDEIHTLVGAGGGEGAMDAANILKPALARGELRAIGATTLDEYQKY
FEKDKALERRFQKVLIDEPDTESAISILRGIKEKYETHHKVQIKDEAIIAAVELSQRYITNRFLPDKAIDLMDEAASKLR
MEINSKPEELDVLDRKIMQLEIEIEAIKREKEESKLKILGMELANLKEERNEIYAKWKQEKDIVDGIQAVKHEIEDFKYE
AERAERDGDYGKVAEIRYGKIKEAQERQENLQKQLLEFQSGNSLIKEEVTREDIAEVVAKWTGIPVTKMLQTEREKLLHL
EDELHKRVVGQEEAIEAVSDAVRRSRAGLQDMKKPVGSFLFLGTTGVGKTELAKALAEYLFDDENAMTRIDMSEYQERHS
VSRLVGAPPGYVGYDEGGQLTEAVRRKPYSVVLLDEIEKAHPDTFNILLQVLDEGRLTDNKGRLADFRNTIIIMTSNMGS
NIIQEKFENLKGSVEAATEAAKNEVLGLLKQTVRPEFINRIDEIVMFTPLTVENISRIVSLQLKSVTKMLALQGITMDAT
PEAIAYLADKGYDPHFGARPVKRVVQREVLNQLSKEILAGNITTDSIILLDAFDGNLVFRNQTEEAK

Sequences:

>Translated_867_residues
MNINKFTIKSQEAIQLSQQLAQRNGQQQIENEHIFKAIFEVDENVAPFILKKLNVNVPLFLQILDSTIQSFPKVSGGDVM
LSRDANKALNEAEIIAQKMNDEYVSIEHLILAIFDSKSKVSQILKDQGVTGKGLKAAIEELRKGERVTSASAEETYNSLN
KYAKNLNELARTGKLDPVIGRDEEIRRVLQILTRRTKNNPMLIGEPGVGKTAIAEGLAHRIVDGDVPENLKDKIVFSLDM
GALIAGAKYKGEFEERLKSVVKEVTAAEGDIVLFIDEIHTLVGAGGGEGAMDAANILKPALARGELRAIGATTLDEYQKY
FEKDKALERRFQKVLIDEPDTESAISILRGIKEKYETHHKVQIKDEAIIAAVELSQRYITNRFLPDKAIDLMDEAASKLR
MEINSKPEELDVLDRKIMQLEIEIEAIKREKEESKLKILGMELANLKEERNEIYAKWKQEKDIVDGIQAVKHEIEDFKYE
AERAERDGDYGKVAEIRYGKIKEAQERQENLQKQLLEFQSGNSLIKEEVTREDIAEVVAKWTGIPVTKMLQTEREKLLHL
EDELHKRVVGQEEAIEAVSDAVRRSRAGLQDMKKPVGSFLFLGTTGVGKTELAKALAEYLFDDENAMTRIDMSEYQERHS
VSRLVGAPPGYVGYDEGGQLTEAVRRKPYSVVLLDEIEKAHPDTFNILLQVLDEGRLTDNKGRLADFRNTIIIMTSNMGS
NIIQEKFENLKGSVEAATEAAKNEVLGLLKQTVRPEFINRIDEIVMFTPLTVENISRIVSLQLKSVTKMLALQGITMDAT
PEAIAYLADKGYDPHFGARPVKRVVQREVLNQLSKEILAGNITTDSIILLDAFDGNLVFRNQTEEAK
>Mature_867_residues
MNINKFTIKSQEAIQLSQQLAQRNGQQQIENEHIFKAIFEVDENVAPFILKKLNVNVPLFLQILDSTIQSFPKVSGGDVM
LSRDANKALNEAEIIAQKMNDEYVSIEHLILAIFDSKSKVSQILKDQGVTGKGLKAAIEELRKGERVTSASAEETYNSLN
KYAKNLNELARTGKLDPVIGRDEEIRRVLQILTRRTKNNPMLIGEPGVGKTAIAEGLAHRIVDGDVPENLKDKIVFSLDM
GALIAGAKYKGEFEERLKSVVKEVTAAEGDIVLFIDEIHTLVGAGGGEGAMDAANILKPALARGELRAIGATTLDEYQKY
FEKDKALERRFQKVLIDEPDTESAISILRGIKEKYETHHKVQIKDEAIIAAVELSQRYITNRFLPDKAIDLMDEAASKLR
MEINSKPEELDVLDRKIMQLEIEIEAIKREKEESKLKILGMELANLKEERNEIYAKWKQEKDIVDGIQAVKHEIEDFKYE
AERAERDGDYGKVAEIRYGKIKEAQERQENLQKQLLEFQSGNSLIKEEVTREDIAEVVAKWTGIPVTKMLQTEREKLLHL
EDELHKRVVGQEEAIEAVSDAVRRSRAGLQDMKKPVGSFLFLGTTGVGKTELAKALAEYLFDDENAMTRIDMSEYQERHS
VSRLVGAPPGYVGYDEGGQLTEAVRRKPYSVVLLDEIEKAHPDTFNILLQVLDEGRLTDNKGRLADFRNTIIIMTSNMGS
NIIQEKFENLKGSVEAATEAAKNEVLGLLKQTVRPEFINRIDEIVMFTPLTVENISRIVSLQLKSVTKMLALQGITMDAT
PEAIAYLADKGYDPHFGARPVKRVVQREVLNQLSKEILAGNITTDSIILLDAFDGNLVFRNQTEEAK

Specific function: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase

COG id: COG0542

COG function: function code O; ATPases with chaperone activity, ATP-binding subunit

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the clpA/clpB family [H]

Homologues:

Organism=Homo sapiens, GI13540606, Length=315, Percent_Identity=40.3174603174603, Blast_Score=221, Evalue=3e-57,
Organism=Escherichia coli, GI1788943, Length=868, Percent_Identity=53.2258064516129, Blast_Score=917, Evalue=0.0,
Organism=Escherichia coli, GI1787109, Length=341, Percent_Identity=44.2815249266862, Blast_Score=288, Evalue=1e-78,
Organism=Saccharomyces cerevisiae, GI6320464, Length=707, Percent_Identity=51.4851485148515, Blast_Score=721, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6323002, Length=856, Percent_Identity=42.2897196261682, Blast_Score=658, Evalue=0.0,

Paralogues:

None

Copy number: 560 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR003959
- InterPro:   IPR018368
- InterPro:   IPR017730
- InterPro:   IPR001270
- InterPro:   IPR019489
- InterPro:   IPR004176
- InterPro:   IPR023150 [H]

Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF02861 Clp_N; PF10431 ClpB_D2-small [H]

EC number: NA

Molecular weight: Translated: 97409; Mature: 97409

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: PS00870 CLPAB_1 ; PS00871 CLPAB_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNINKFTIKSQEAIQLSQQLAQRNGQQQIENEHIFKAIFEVDENVAPFILKKLNVNVPLF
CCCCCEEECCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHH
LQILDSTIQSFPKVSGGDVMLSRDANKALNEAEIIAQKMNDEYVSIEHLILAIFDSKSKV
HHHHHHHHHHCCCCCCCCEEEECCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHH
SQILKDQGVTGKGLKAAIEELRKGERVTSASAEETYNSLNKYAKNLNELARTGKLDPVIG
HHHHHHCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
RDEEIRRVLQILTRRTKNNPMLIGEPGVGKTAIAEGLAHRIVDGDVPENLKDKIVFSLDM
CCHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHCCCCCCCCCHHCEEEEECH
GALIAGAKYKGEFEERLKSVVKEVTAAEGDIVLFIDEIHTLVGAGGGEGAMDAANILKPA
HHHHCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHCCCCCCCCHHHHHHHHHH
LARGELRAIGATTLDEYQKYFEKDKALERRFQKVLIDEPDTESAISILRGIKEKYETHHK
HHCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCE
VQIKDEAIIAAVELSQRYITNRFLPDKAIDLMDEAASKLRMEINSKPEELDVLDRKIMQL
EEECCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
EIEIEAIKREKEESKLKILGMELANLKEERNEIYAKWKQEKDIVDGIQAVKHEIEDFKYE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AERAERDGDYGKVAEIRYGKIKEAQERQENLQKQLLEFQSGNSLIKEEVTREDIAEVVAK
HHHHHCCCCCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
WTGIPVTKMLQTEREKLLHLEDELHKRVVGQEEAIEAVSDAVRRSRAGLQDMKKPVGSFL
HCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHCEE
FLGTTGVGKTELAKALAEYLFDDENAMTRIDMSEYQERHSVSRLVGAPPGYVGYDEGGQL
EEECCCCCHHHHHHHHHHHHHCCCCHHEECCHHHHHHHHHHHHHHCCCCCCCCCCCCCHH
TEAVRRKPYSVVLLDEIEKAHPDTFNILLQVLDEGRLTDNKGRLADFRNTIIIMTSNMGS
HHHHHCCCCEEEEEHHHHHHCCHHHHHHHHHHHCCCCCCCCCCHHHCCCEEEEEECCCCC
NIIQEKFENLKGSVEAATEAAKNEVLGLLKQTVRPEFINRIDEIVMFTPLTVENISRIVS
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHH
LQLKSVTKMLALQGITMDATPEAIAYLADKGYDPHFGARPVKRVVQREVLNQLSKEILAG
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCC
NITTDSIILLDAFDGNLVFRNQTEEAK
CCCCCCEEEEEECCCCEEEECCCCCCC
>Mature Secondary Structure
MNINKFTIKSQEAIQLSQQLAQRNGQQQIENEHIFKAIFEVDENVAPFILKKLNVNVPLF
CCCCCEEECCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHH
LQILDSTIQSFPKVSGGDVMLSRDANKALNEAEIIAQKMNDEYVSIEHLILAIFDSKSKV
HHHHHHHHHHCCCCCCCCEEEECCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHH
SQILKDQGVTGKGLKAAIEELRKGERVTSASAEETYNSLNKYAKNLNELARTGKLDPVIG
HHHHHHCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
RDEEIRRVLQILTRRTKNNPMLIGEPGVGKTAIAEGLAHRIVDGDVPENLKDKIVFSLDM
CCHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHCCCCCCCCCHHCEEEEECH
GALIAGAKYKGEFEERLKSVVKEVTAAEGDIVLFIDEIHTLVGAGGGEGAMDAANILKPA
HHHHCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHCCCCCCCCHHHHHHHHHH
LARGELRAIGATTLDEYQKYFEKDKALERRFQKVLIDEPDTESAISILRGIKEKYETHHK
HHCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCE
VQIKDEAIIAAVELSQRYITNRFLPDKAIDLMDEAASKLRMEINSKPEELDVLDRKIMQL
EEECCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
EIEIEAIKREKEESKLKILGMELANLKEERNEIYAKWKQEKDIVDGIQAVKHEIEDFKYE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AERAERDGDYGKVAEIRYGKIKEAQERQENLQKQLLEFQSGNSLIKEEVTREDIAEVVAK
HHHHHCCCCCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
WTGIPVTKMLQTEREKLLHLEDELHKRVVGQEEAIEAVSDAVRRSRAGLQDMKKPVGSFL
HCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHCEE
FLGTTGVGKTELAKALAEYLFDDENAMTRIDMSEYQERHSVSRLVGAPPGYVGYDEGGQL
EEECCCCCHHHHHHHHHHHHHCCCCHHEECCHHHHHHHHHHHHHHCCCCCCCCCCCCCHH
TEAVRRKPYSVVLLDEIEKAHPDTFNILLQVLDEGRLTDNKGRLADFRNTIIIMTSNMGS
HHHHHCCCCEEEEEHHHHHHCCHHHHHHHHHHHCCCCCCCCCCHHHCCCEEEEEECCCCC
NIIQEKFENLKGSVEAATEAAKNEVLGLLKQTVRPEFINRIDEIVMFTPLTVENISRIVS
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHH
LQLKSVTKMLALQGITMDATPEAIAYLADKGYDPHFGARPVKRVVQREVLNQLSKEILAG
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCC
NITTDSIILLDAFDGNLVFRNQTEEAK
CCCCCCEEEEEECCCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12663928 [H]