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The map label for this gene is aspB [H]

Identifier: 146300026

GI number: 146300026

Start: 2736364

End: 2737560

Strand: Reverse

Name: aspB [H]

Synonym: Fjoh_2271

Alternate gene names: 146300026

Gene position: 2737560-2736364 (Counterclockwise)

Preceding gene: 146300032

Following gene: 146300025

Centisome position: 44.9

GC content: 36.51

Gene sequence:

>1197_bases
ATGCCAACAATTTCTCAAAAGGGCAGAAACATGCCTGAATCACCGATACGCAAGCTGGCTCCTTATGCTGATTTAGCAAA
GAAAAAAGGACACAAGGTGTATCACTTAAACATTGGTCAACCGGATATCAAGACACCGGAAGTGGCCATCGAGGCGGTAA
AAAATATTGATTTGAGTATTATAGAATACAGTCCGTCTGCCGGATATGAAAGCTATAGAAAAAAATTAGCTCATTTTTAC
CAGCGCCAAAATGTAAACGTTAACACAGAAGACATCATTGTTACAACTGGTGGTTCTGAAGCCTTACTTTTTGCACTGGC
CACAATTACAGATCCAGGAGATGAAATCATTATCCCGGAACCATTTTATGCTAATTATCATGCATTTGCATCTTCTACAA
GTGCAACTGTAGTGCCTCTTGTTTCTACTATTGAAACGGCTTTTGCACTGCCAAGTATTGACGAAGTAGAAAAGTTAATT
ACGCCAAAAACAAAAGCTATTCTGATTTGCAACCCTGGAAATCCGACTGGATATTTATATTCTGAAACAGAAATTAAACA
ATTAGCAGAATTAATTAAAAAACATGATTTATATTTAATTGCTGACGAAGTTTACCGCGAATTTTTATATGATGGAGATG
ATGTGCATTTTTCTGTAATGAATCTGGAAGATGTACAGCAAAACGTAATCATGGTAGATTCTGTTTCTAAACGTTACAGT
ATGTGCGGTGCCAGAATTGGATGTTTGATTACTAAAAATAAAGATGTTCTTGCAACTGTTATGAAATTTGCTCAGGCGCG
TTTAAGTCCGCCAACAATTGAGCAGATTGCCTGTGAAGCAGCTATTGATACGCCGCAAAGTTATTTTGACGAAGTAATTG
GCGAATATAAAGAACGTCGTAACACCTTAATTTCTGAATTAAATAAAATTGAAGGTGTCATTGTAACGAAACCAAAAGGT
GCTTTTTACTGTATTGCCCAGCTGCCAATTGAAGATTCTGATGATTTCGCTCAATGGCTTTTAGAAAGTTATAATTTAAA
CGGCGAAACTGTTATGATCGCACCCGCAAAAGGATTTTATTCTACTCCGGGAATGGGATTGAATCAGGTGCGAATTGCAT
ACGTTTTAAACAAAAAAGATCTAATTACAGCAGTAAACATCTTAAAAGAGGCTTTATTGGTGTACAACAATAGATAA

Upstream 100 bases:

>100_bases
AGCAAATATATTTATTATTGTTACATTTTTATAAGTACTCGTATTGTTTACGTTAATTTCGAAAAAAAAATGCAAATTTG
CACTTCAATAATTTATACTC

Downstream 100 bases:

>100_bases
AACAAACTAAACTTAAACTCTCAAAAGACAATAACGATTCCTGTTATTGTCTTTTGTATTTTGGAACAATTTTAAATTAT
ATCTAAAAAGGATCGATTAA

Product: aspartate aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 398; Mature: 397

Protein sequence:

>398_residues
MPTISQKGRNMPESPIRKLAPYADLAKKKGHKVYHLNIGQPDIKTPEVAIEAVKNIDLSIIEYSPSAGYESYRKKLAHFY
QRQNVNVNTEDIIVTTGGSEALLFALATITDPGDEIIIPEPFYANYHAFASSTSATVVPLVSTIETAFALPSIDEVEKLI
TPKTKAILICNPGNPTGYLYSETEIKQLAELIKKHDLYLIADEVYREFLYDGDDVHFSVMNLEDVQQNVIMVDSVSKRYS
MCGARIGCLITKNKDVLATVMKFAQARLSPPTIEQIACEAAIDTPQSYFDEVIGEYKERRNTLISELNKIEGVIVTKPKG
AFYCIAQLPIEDSDDFAQWLLESYNLNGETVMIAPAKGFYSTPGMGLNQVRIAYVLNKKDLITAVNILKEALLVYNNR

Sequences:

>Translated_398_residues
MPTISQKGRNMPESPIRKLAPYADLAKKKGHKVYHLNIGQPDIKTPEVAIEAVKNIDLSIIEYSPSAGYESYRKKLAHFY
QRQNVNVNTEDIIVTTGGSEALLFALATITDPGDEIIIPEPFYANYHAFASSTSATVVPLVSTIETAFALPSIDEVEKLI
TPKTKAILICNPGNPTGYLYSETEIKQLAELIKKHDLYLIADEVYREFLYDGDDVHFSVMNLEDVQQNVIMVDSVSKRYS
MCGARIGCLITKNKDVLATVMKFAQARLSPPTIEQIACEAAIDTPQSYFDEVIGEYKERRNTLISELNKIEGVIVTKPKG
AFYCIAQLPIEDSDDFAQWLLESYNLNGETVMIAPAKGFYSTPGMGLNQVRIAYVLNKKDLITAVNILKEALLVYNNR
>Mature_397_residues
PTISQKGRNMPESPIRKLAPYADLAKKKGHKVYHLNIGQPDIKTPEVAIEAVKNIDLSIIEYSPSAGYESYRKKLAHFYQ
RQNVNVNTEDIIVTTGGSEALLFALATITDPGDEIIIPEPFYANYHAFASSTSATVVPLVSTIETAFALPSIDEVEKLIT
PKTKAILICNPGNPTGYLYSETEIKQLAELIKKHDLYLIADEVYREFLYDGDDVHFSVMNLEDVQQNVIMVDSVSKRYSM
CGARIGCLITKNKDVLATVMKFAQARLSPPTIEQIACEAAIDTPQSYFDEVIGEYKERRNTLISELNKIEGVIVTKPKGA
FYCIAQLPIEDSDDFAQWLLESYNLNGETVMIAPAKGFYSTPGMGLNQVRIAYVLNKKDLITAVNILKEALLVYNNR

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=380, Percent_Identity=25.7894736842105, Blast_Score=122, Evalue=6e-28,
Organism=Homo sapiens, GI169881279, Length=380, Percent_Identity=25.7894736842105, Blast_Score=122, Evalue=6e-28,
Organism=Homo sapiens, GI56713256, Length=322, Percent_Identity=28.8819875776398, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI56713254, Length=322, Percent_Identity=28.8819875776398, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI4507369, Length=336, Percent_Identity=24.1071428571429, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI149944424, Length=241, Percent_Identity=25.3112033195021, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI187936925, Length=287, Percent_Identity=26.1324041811847, Blast_Score=89, Evalue=8e-18,
Organism=Homo sapiens, GI14211921, Length=287, Percent_Identity=26.1324041811847, Blast_Score=89, Evalue=8e-18,
Organism=Homo sapiens, GI19263340, Length=345, Percent_Identity=24.9275362318841, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI215599424, Length=345, Percent_Identity=24.9275362318841, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI4885351, Length=348, Percent_Identity=26.1494252873563, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI169881281, Length=230, Percent_Identity=24.7826086956522, Blast_Score=79, Evalue=6e-15,
Organism=Escherichia coli, GI1788627, Length=315, Percent_Identity=31.1111111111111, Blast_Score=142, Evalue=4e-35,
Organism=Escherichia coli, GI1788722, Length=396, Percent_Identity=27.2727272727273, Blast_Score=125, Evalue=7e-30,
Organism=Escherichia coli, GI1786816, Length=372, Percent_Identity=23.6559139784946, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1790797, Length=308, Percent_Identity=21.7532467532468, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1787710, Length=196, Percent_Identity=28.0612244897959, Blast_Score=69, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17567663, Length=399, Percent_Identity=25.062656641604, Blast_Score=123, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI71994476, Length=402, Percent_Identity=28.6069651741293, Blast_Score=120, Evalue=9e-28,
Organism=Caenorhabditis elegans, GI71994472, Length=402, Percent_Identity=28.6069651741293, Blast_Score=120, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI17567369, Length=326, Percent_Identity=30.0613496932515, Blast_Score=102, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI71981209, Length=345, Percent_Identity=26.3768115942029, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI71981215, Length=203, Percent_Identity=28.0788177339901, Blast_Score=66, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6322401, Length=316, Percent_Identity=28.4810126582279, Blast_Score=116, Evalue=7e-27,
Organism=Saccharomyces cerevisiae, GI6320317, Length=364, Percent_Identity=28.8461538461538, Blast_Score=102, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6323118, Length=356, Percent_Identity=26.685393258427, Blast_Score=92, Evalue=1e-19,
Organism=Drosophila melanogaster, GI28573069, Length=393, Percent_Identity=25.9541984732824, Blast_Score=118, Evalue=8e-27,
Organism=Drosophila melanogaster, GI24646114, Length=393, Percent_Identity=25.9541984732824, Blast_Score=118, Evalue=8e-27,
Organism=Drosophila melanogaster, GI28573067, Length=393, Percent_Identity=25.9541984732824, Blast_Score=118, Evalue=8e-27,
Organism=Drosophila melanogaster, GI28573065, Length=393, Percent_Identity=25.9541984732824, Blast_Score=118, Evalue=8e-27,
Organism=Drosophila melanogaster, GI18859735, Length=356, Percent_Identity=25.2808988764045, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI45551451, Length=347, Percent_Identity=28.8184438040346, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24641770, Length=347, Percent_Identity=28.8184438040346, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24641760, Length=347, Percent_Identity=28.8184438040346, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24641768, Length=347, Percent_Identity=28.8184438040346, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24641766, Length=347, Percent_Identity=28.8184438040346, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24641764, Length=347, Percent_Identity=28.8184438040346, Blast_Score=107, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 44362; Mature: 44231

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTISQKGRNMPESPIRKLAPYADLAKKKGHKVYHLNIGQPDIKTPEVAIEAVKNIDLSI
CCCCCCCCCCCCHHHHHHHCCHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHCCCEEE
IEYSPSAGYESYRKKLAHFYQRQNVNVNTEDIIVTTGGSEALLFALATITDPGDEIIIPE
EEECCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCEEEEEEEHHCCCCCCEEECC
PFYANYHAFASSTSATVVPLVSTIETAFALPSIDEVEKLITPKTKAILICNPGNPTGYLY
CCCCCHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCCEEEEECCCCCCCEEE
SETEIKQLAELIKKHDLYLIADEVYREFLYDGDDVHFSVMNLEDVQQNVIMVDSVSKRYS
CHHHHHHHHHHHHHCCEEEEHHHHHHHHHCCCCCEEEEEECHHHHHCCEEEEECHHHHHH
MCGARIGCLITKNKDVLATVMKFAQARLSPPTIEQIACEAAIDTPQSYFDEVIGEYKERR
HHCCCEEEEEECCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHH
NTLISELNKIEGVIVTKPKGAFYCIAQLPIEDSDDFAQWLLESYNLNGETVMIAPAKGFY
HHHHHHHHHHCEEEEECCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCC
STPGMGLNQVRIAYVLNKKDLITAVNILKEALLVYNNR
CCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PTISQKGRNMPESPIRKLAPYADLAKKKGHKVYHLNIGQPDIKTPEVAIEAVKNIDLSI
CCCCCCCCCCCHHHHHHHCCHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHCCCEEE
IEYSPSAGYESYRKKLAHFYQRQNVNVNTEDIIVTTGGSEALLFALATITDPGDEIIIPE
EEECCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCEEEEEEEHHCCCCCCEEECC
PFYANYHAFASSTSATVVPLVSTIETAFALPSIDEVEKLITPKTKAILICNPGNPTGYLY
CCCCCHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCCEEEEECCCCCCCEEE
SETEIKQLAELIKKHDLYLIADEVYREFLYDGDDVHFSVMNLEDVQQNVIMVDSVSKRYS
CHHHHHHHHHHHHHCCEEEEHHHHHHHHHCCCCCEEEEEECHHHHHCCEEEEECHHHHHH
MCGARIGCLITKNKDVLATVMKFAQARLSPPTIEQIACEAAIDTPQSYFDEVIGEYKERR
HHCCCEEEEEECCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHH
NTLISELNKIEGVIVTKPKGAFYCIAQLPIEDSDDFAQWLLESYNLNGETVMIAPAKGFY
HHHHHHHHHHCEEEEECCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCC
STPGMGLNQVRIAYVLNKKDLITAVNILKEALLVYNNR
CCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8760912; 9384377 [H]