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The map label for this gene is uidA [H]

Identifier: 146299840

GI number: 146299840

Start: 2469121

End: 2470923

Strand: Direct

Name: uidA [H]

Synonym: Fjoh_2082

Alternate gene names: 146299840

Gene position: 2469121-2470923 (Clockwise)

Preceding gene: 146299839

Following gene: 146299842

Centisome position: 40.5

GC content: 35.05

Gene sequence:

>1803_bases
ATGAAAAAAATTGTAATGCTGTGCTGTACTTTTCTACTGATGGGAAAAGCAATAGCACAGGAAATTCCGTTGGTTTCTAA
TATTTCGTCAAGGAACAATATTACTTTAAATGGAAAATGGAGTTATATCGTAGATCCGCTAGAAAACGGGTATTACGATT
ACCGATTAATGCCTTTTAAAAATAATGGATTCTTCGAAAATAAAAAATTCAATACCACAGATTTAACCGAATATAATTTT
GCGACTTCTGCCACAATGGATATTCCATCAGATTGGAACAGCAAAGACGAAAGATTGTTTTTTTATGAAGGAACTGTTTG
GTTTCAGAAAGACTTTAATTATAAAAAAGATTCTAAAACCAAAGGGATTCTTCATTTTGGAGCAGTCAATTATGATGCAA
AAGTCTATGTAAACGGAAAACTGGCAGGAACACACGTTGGAGGTTATACACCTTTCAATTTTGATGTAACTGATCTATTA
GTCGACGGGAATAATTTTGTAGTTGTAAAAGTAGATAACAAGCGTCACAAAGATAATGTTCCAACTGTAAATATGGATTG
GTGGAATTACGGCGGAATTACAAGAGATGTTACTTTGGCTCAGGTTCCGAATACGTATGTGGAAGATTATTTGGTTCAAT
TGGATAAAAAAGAAAAAGGCAAGATTTCCGGCTGGATAAAACTGAATAGTGAAACAGCAAATCAATCCATTTCAGTTTCT
ATTCCAGAATTAAAAATCAAAAAAAGCATTACAACAGATGCTAAAGGAATGGCGTATTTTGAAATTAAAGCCAATCCGGT
TTTATGGACGCCGGAAAAACCAAAATTATACGATGTAACCATTTCCAAAGCCGATGAAAATATAACAGATCAAATTGGTT
TTAGAACTATTGAAACCAAAGGAAAAGAGATTCTGTTAAACGGAAAAAAAGTCTTTTTAAGAGGAATCAGTATTCATGAA
GAAGCACCTTTCAGATCGGGTAGAGCTTGGTCTGAAGATGATGCGATAACGTTATTGAATTGGGCCAAAGAGTTAGGCTG
TAATTATGTTCGTCTGGCACATTATCCTCACAACGAAAATATGGTAAGACAAGCTGAGAAAATGGGAATTATGATTTGGT
CTGAAGTTCCTGTTTATTGGACCATTTCATGGACAAATCCTGATACGTATGCTAATGCAGAGCGTCAATTACACGATATG
ATTTACAGAGATAAAAACCGCTGCGGAATCGTGATTTGGTCTATCGCCAATGAAACACCGCATAGTGATGAAAGAGATGT
TTTTCTGAGTAAATTGGCTAAATATGCACGCACGCAGGATAATACTCGTTTAATTAGTATGGCGATGGAAGTTACCAAAA
GTCCAAACAATGTAAATACACTTCATGATAACATGAATGAATTTGTAGACATTGTAAGTTTCAATCAATATCTGGGCTGG
TACAGAGGAACGAATGAATCTTGTAAAGATATGCAATGGGTGATTCCGTATAACAAACCAGTTATTATCAGCGAGTTCGG
AGGAGAAGCTTTACAAGGACTTCACGGAGATAAAAAAGAACGCTGGAACGAAGAATATCAGGAAGAATTATACATTCAAA
ATACTCAGATGTTTAATCGTATAGAAGGTTTAGCAGGAGTTTCACCCTGGATTTTAGTTGATTTTAGATCACCAAGAAGG
CAATTGCCAAACATTCAGGATTTCTTTAACCGCAAAGGCTTAATCTCAGATCAGGGAATTAAAAAGAAAGCTTTTTATGT
AATGAAAGACTGGTATGCACAGAAAGAGCAGGAATATAAATAA

Upstream 100 bases:

>100_bases
AGCTATGTGTATTTATGCAAGTGAAACGCCTTTTATGCTCAAAGTAGTGCTATGTTTCTATGTGTTTAAAAATAATTGTA
GATAATTAAAAATAAAAACT

Downstream 100 bases:

>100_bases
GTGAGTTAGAGTTTTAGATAAAGAGGAAAACCTTTGGAATCAGAAATGATTTTAAAGGTTTTTTGGTTTTTGGAAATGTT
GTTTTTGAACCAAAAGTAAT

Product: beta-glucuronidase

Products: NA

Alternate protein names: GUS; Beta-D-glucuronoside glucuronosohydrolase [H]

Number of amino acids: Translated: 600; Mature: 600

Protein sequence:

>600_residues
MKKIVMLCCTFLLMGKAIAQEIPLVSNISSRNNITLNGKWSYIVDPLENGYYDYRLMPFKNNGFFENKKFNTTDLTEYNF
ATSATMDIPSDWNSKDERLFFYEGTVWFQKDFNYKKDSKTKGILHFGAVNYDAKVYVNGKLAGTHVGGYTPFNFDVTDLL
VDGNNFVVVKVDNKRHKDNVPTVNMDWWNYGGITRDVTLAQVPNTYVEDYLVQLDKKEKGKISGWIKLNSETANQSISVS
IPELKIKKSITTDAKGMAYFEIKANPVLWTPEKPKLYDVTISKADENITDQIGFRTIETKGKEILLNGKKVFLRGISIHE
EAPFRSGRAWSEDDAITLLNWAKELGCNYVRLAHYPHNENMVRQAEKMGIMIWSEVPVYWTISWTNPDTYANAERQLHDM
IYRDKNRCGIVIWSIANETPHSDERDVFLSKLAKYARTQDNTRLISMAMEVTKSPNNVNTLHDNMNEFVDIVSFNQYLGW
YRGTNESCKDMQWVIPYNKPVIISEFGGEALQGLHGDKKERWNEEYQEELYIQNTQMFNRIEGLAGVSPWILVDFRSPRR
QLPNIQDFFNRKGLISDQGIKKKAFYVMKDWYAQKEQEYK

Sequences:

>Translated_600_residues
MKKIVMLCCTFLLMGKAIAQEIPLVSNISSRNNITLNGKWSYIVDPLENGYYDYRLMPFKNNGFFENKKFNTTDLTEYNF
ATSATMDIPSDWNSKDERLFFYEGTVWFQKDFNYKKDSKTKGILHFGAVNYDAKVYVNGKLAGTHVGGYTPFNFDVTDLL
VDGNNFVVVKVDNKRHKDNVPTVNMDWWNYGGITRDVTLAQVPNTYVEDYLVQLDKKEKGKISGWIKLNSETANQSISVS
IPELKIKKSITTDAKGMAYFEIKANPVLWTPEKPKLYDVTISKADENITDQIGFRTIETKGKEILLNGKKVFLRGISIHE
EAPFRSGRAWSEDDAITLLNWAKELGCNYVRLAHYPHNENMVRQAEKMGIMIWSEVPVYWTISWTNPDTYANAERQLHDM
IYRDKNRCGIVIWSIANETPHSDERDVFLSKLAKYARTQDNTRLISMAMEVTKSPNNVNTLHDNMNEFVDIVSFNQYLGW
YRGTNESCKDMQWVIPYNKPVIISEFGGEALQGLHGDKKERWNEEYQEELYIQNTQMFNRIEGLAGVSPWILVDFRSPRR
QLPNIQDFFNRKGLISDQGIKKKAFYVMKDWYAQKEQEYK
>Mature_600_residues
MKKIVMLCCTFLLMGKAIAQEIPLVSNISSRNNITLNGKWSYIVDPLENGYYDYRLMPFKNNGFFENKKFNTTDLTEYNF
ATSATMDIPSDWNSKDERLFFYEGTVWFQKDFNYKKDSKTKGILHFGAVNYDAKVYVNGKLAGTHVGGYTPFNFDVTDLL
VDGNNFVVVKVDNKRHKDNVPTVNMDWWNYGGITRDVTLAQVPNTYVEDYLVQLDKKEKGKISGWIKLNSETANQSISVS
IPELKIKKSITTDAKGMAYFEIKANPVLWTPEKPKLYDVTISKADENITDQIGFRTIETKGKEILLNGKKVFLRGISIHE
EAPFRSGRAWSEDDAITLLNWAKELGCNYVRLAHYPHNENMVRQAEKMGIMIWSEVPVYWTISWTNPDTYANAERQLHDM
IYRDKNRCGIVIWSIANETPHSDERDVFLSKLAKYARTQDNTRLISMAMEVTKSPNNVNTLHDNMNEFVDIVSFNQYLGW
YRGTNESCKDMQWVIPYNKPVIISEFGGEALQGLHGDKKERWNEEYQEELYIQNTQMFNRIEGLAGVSPWILVDFRSPRR
QLPNIQDFFNRKGLISDQGIKKKAFYVMKDWYAQKEQEYK

Specific function: Unknown

COG id: COG3250

COG function: function code G; Beta-galactosidase/beta-glucuronidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 2 family [H]

Homologues:

Organism=Homo sapiens, GI268834192, Length=649, Percent_Identity=25.115562403698, Blast_Score=179, Evalue=9e-45,
Organism=Escherichia coli, GI1787903, Length=583, Percent_Identity=27.1012006861063, Blast_Score=189, Evalue=3e-49,
Organism=Escherichia coli, GI48994920, Length=384, Percent_Identity=25.5208333333333, Blast_Score=94, Evalue=3e-20,
Organism=Escherichia coli, GI1786539, Length=369, Percent_Identity=24.390243902439, Blast_Score=90, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI17510825, Length=618, Percent_Identity=25.8899676375405, Blast_Score=178, Evalue=8e-45,
Organism=Drosophila melanogaster, GI19922582, Length=568, Percent_Identity=28.5211267605634, Blast_Score=202, Evalue=6e-52,
Organism=Drosophila melanogaster, GI62471735, Length=568, Percent_Identity=28.5211267605634, Blast_Score=202, Evalue=7e-52,
Organism=Drosophila melanogaster, GI24655438, Length=568, Percent_Identity=28.5211267605634, Blast_Score=201, Evalue=9e-52,
Organism=Drosophila melanogaster, GI24651745, Length=572, Percent_Identity=26.7482517482518, Blast_Score=188, Evalue=8e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008979
- InterPro:   IPR006101
- InterPro:   IPR013812
- InterPro:   IPR006104
- InterPro:   IPR006102
- InterPro:   IPR006103
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00703 Glyco_hydro_2; PF02836 Glyco_hydro_2_C; PF02837 Glyco_hydro_2_N [H]

EC number: =3.2.1.31 [H]

Molecular weight: Translated: 69619; Mature: 69619

Theoretical pI: Translated: 7.59; Mature: 7.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKIVMLCCTFLLMGKAIAQEIPLVSNISSRNNITLNGKWSYIVDPLENGYYDYRLMPFK
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCEEEEEECCCCCCEEEEEEEEEC
NNGFFENKKFNTTDLTEYNFATSATMDIPSDWNSKDERLFFYEGTVWFQKDFNYKKDSKT
CCCCCCCCCCCCCCCCEECCCCEEEEECCCCCCCCCCEEEEEECEEEEEECCCCCCCCCC
KGILHFGAVNYDAKVYVNGKLAGTHVGGYTPFNFDVTDLLVDGNNFVVVKVDNKRHKDNV
CCEEEEEEECCCEEEEECCEEEEEECCCCCCCCCCEEEEEECCCCEEEEEECCCCCCCCC
PTVNMDWWNYGGITRDVTLAQVPNTYVEDYLVQLDKKEKGKISGWIKLNSETANQSISVS
CEEEECCCCCCCEEECEEEEECCCHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCEEEEE
IPELKIKKSITTDAKGMAYFEIKANPVLWTPEKPKLYDVTISKADENITDQIGFRTIETK
CCCEEEEECCCCCCCCEEEEEEECCEEEECCCCCEEEEEEEECCCCCCHHHHCCEEEECC
GKEILLNGKKVFLRGISIHEEAPFRSGRAWSEDDAITLLNWAKELGCNYVRLAHYPHNEN
CCEEEEECCEEEEEECEECCCCCCCCCCCCCCCCCCHHHHHHHHHCCCEEEEEECCCCCH
MVRQAEKMGIMIWSEVPVYWTISWTNPDTYANAERQLHDMIYRDKNRCGIVIWSIANETP
HHHHHHHCCEEEEECCCEEEEEEECCCCCCCCHHHHHHHHHHCCCCCCEEEEEEECCCCC
HSDERDVFLSKLAKYARTQDNTRLISMAMEVTKSPNNVNTLHDNMNEFVDIVSFNQYLGW
CCCHHHHHHHHHHHHHHCCCCHHEEEEHHHHHCCCCCCHHHHHCHHHHHHHHHHHHHHCE
YRGTNESCKDMQWVIPYNKPVIISEFGGEALQGLHGDKKERWNEEYQEELYIQNTQMFNR
ECCCCCCCCCEEEEECCCCCEEEECCCCHHHHCCCCCHHHHHHHHHHHHHEEEHHHHHHH
IEGLAGVSPWILVDFRSPRRQLPNIQDFFNRKGLISDQGIKKKAFYVMKDWYAQKEQEYK
HHHCCCCCCEEEEEECCHHHHCCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKKIVMLCCTFLLMGKAIAQEIPLVSNISSRNNITLNGKWSYIVDPLENGYYDYRLMPFK
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCEEEEEECCCCCCEEEEEEEEEC
NNGFFENKKFNTTDLTEYNFATSATMDIPSDWNSKDERLFFYEGTVWFQKDFNYKKDSKT
CCCCCCCCCCCCCCCCEECCCCEEEEECCCCCCCCCCEEEEEECEEEEEECCCCCCCCCC
KGILHFGAVNYDAKVYVNGKLAGTHVGGYTPFNFDVTDLLVDGNNFVVVKVDNKRHKDNV
CCEEEEEEECCCEEEEECCEEEEEECCCCCCCCCCEEEEEECCCCEEEEEECCCCCCCCC
PTVNMDWWNYGGITRDVTLAQVPNTYVEDYLVQLDKKEKGKISGWIKLNSETANQSISVS
CEEEECCCCCCCEEECEEEEECCCHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCEEEEE
IPELKIKKSITTDAKGMAYFEIKANPVLWTPEKPKLYDVTISKADENITDQIGFRTIETK
CCCEEEEECCCCCCCCEEEEEEECCEEEECCCCCEEEEEEEECCCCCCHHHHCCEEEECC
GKEILLNGKKVFLRGISIHEEAPFRSGRAWSEDDAITLLNWAKELGCNYVRLAHYPHNEN
CCEEEEECCEEEEEECEECCCCCCCCCCCCCCCCCCHHHHHHHHHCCCEEEEEECCCCCH
MVRQAEKMGIMIWSEVPVYWTISWTNPDTYANAERQLHDMIYRDKNRCGIVIWSIANETP
HHHHHHHCCEEEEECCCEEEEEEECCCCCCCCHHHHHHHHHHCCCCCCEEEEEEECCCCC
HSDERDVFLSKLAKYARTQDNTRLISMAMEVTKSPNNVNTLHDNMNEFVDIVSFNQYLGW
CCCHHHHHHHHHHHHHHCCCCHHEEEEHHHHHCCCCCCHHHHHCHHHHHHHHHHHHHHCE
YRGTNESCKDMQWVIPYNKPVIISEFGGEALQGLHGDKKERWNEEYQEELYIQNTQMFNR
ECCCCCCCCCEEEEECCCCCEEEECCCCHHHHCCCCCHHHHHHHHHHHHHEEEHHHHHHH
IEGLAGVSPWILVDFRSPRRQLPNIQDFFNRKGLISDQGIKKKAFYVMKDWYAQKEQEYK
HHHCCCCCCEEEEEECCHHHHCCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3534890; 8125312; 2103475; 9097039; 9278503 [H]