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The map label for this gene is clpP [H]

Identifier: 146299462

GI number: 146299462

Start: 1972641

End: 1973315

Strand: Direct

Name: clpP [H]

Synonym: Fjoh_1702

Alternate gene names: 146299462

Gene position: 1972641-1973315 (Clockwise)

Preceding gene: 146299461

Following gene: 146299463

Centisome position: 32.35

GC content: 37.04

Gene sequence:

>675_bases
ATGAACTACGGTAAAGAATTTAAAAATTTTGCTACAAAGCACCACGGAGTAAATGCCATGTATTATGACAAAATCATCAG
CGCTATGACGCCGACGAATTTAACTCCAAATATTATTGAAGAACGTCAATTAAATGTTTCTATTCTAGACGTTTTCTCAA
GATTAATGATGGATAGAATTATCTTTTTAGGAACAGGTATCGATGACCAGATTGCAAATGTTGTACAAGCGCAGTTATTA
TTCTTAGAAAGTGCCGATGCATCAAAAGATATCCAAATCTATTTAAATTCTCCAGGAGGAAGCGTTTATGCAGGTCTTGG
GATTTATGATACAATGCAGTACATCAAGCCAGACGTTGCAACAATTTGTACAGGAATGGCAGCTTCTATGGGAGCAGTTT
TATTATGTGCAGGAGCAGCAGGAAAACGTTCGGCTCTGCCACATTCACGAGTTATGATTCACCAGCCGTCTGGAGGTGCA
CAAGGTGTAGCAACAGATATGGAAATTAATTTACGTGAAATGTTGAAATTGAAAGATGAATTATATCACATTATTTCACA
ACATTCAGGTCAGTCTTTCGAAAGAGTTCATAAAGATAGTGAGCGTGATTACTGGATGATTGCTGATGAAGCAAAAGAAT
ACGGAATGATCGACGAAGTATTAAGAAGAGGATAA

Upstream 100 bases:

>100_bases
AAAAAGAAGACAAATTGGCATCCTTTATAAAAAGGTATGAACTTTGTTTAATTCGTTTAAGTCACTTTGACTTTAGACTT
TTCAACTTTAAACTAAAAAT

Downstream 100 bases:

>100_bases
TTTTTATTAAGGTTTAAAATCTTTCAGGTTACAGGTTTCAAGTTGTCTAAAAAGCTTGTAACCTGTAACTTGAAAATTGA
AACAAAAAATAAATATTAAG

Product: endopeptidase Clp

Products: NA

Alternate protein names: Endopeptidase Clp [H]

Number of amino acids: Translated: 224; Mature: 224

Protein sequence:

>224_residues
MNYGKEFKNFATKHHGVNAMYYDKIISAMTPTNLTPNIIEERQLNVSILDVFSRLMMDRIIFLGTGIDDQIANVVQAQLL
FLESADASKDIQIYLNSPGGSVYAGLGIYDTMQYIKPDVATICTGMAASMGAVLLCAGAAGKRSALPHSRVMIHQPSGGA
QGVATDMEINLREMLKLKDELYHIISQHSGQSFERVHKDSERDYWMIADEAKEYGMIDEVLRRG

Sequences:

>Translated_224_residues
MNYGKEFKNFATKHHGVNAMYYDKIISAMTPTNLTPNIIEERQLNVSILDVFSRLMMDRIIFLGTGIDDQIANVVQAQLL
FLESADASKDIQIYLNSPGGSVYAGLGIYDTMQYIKPDVATICTGMAASMGAVLLCAGAAGKRSALPHSRVMIHQPSGGA
QGVATDMEINLREMLKLKDELYHIISQHSGQSFERVHKDSERDYWMIADEAKEYGMIDEVLRRG
>Mature_224_residues
MNYGKEFKNFATKHHGVNAMYYDKIISAMTPTNLTPNIIEERQLNVSILDVFSRLMMDRIIFLGTGIDDQIANVVQAQLL
FLESADASKDIQIYLNSPGGSVYAGLGIYDTMQYIKPDVATICTGMAASMGAVLLCAGAAGKRSALPHSRVMIHQPSGGA
QGVATDMEINLREMLKLKDELYHIISQHSGQSFERVHKDSERDYWMIADEAKEYGMIDEVLRRG

Specific function: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins [H]

COG id: COG0740

COG function: function code OU; Protease subunit of ATP-dependent Clp proteases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S14 family [H]

Homologues:

Organism=Homo sapiens, GI5174419, Length=188, Percent_Identity=50, Blast_Score=194, Evalue=5e-50,
Organism=Escherichia coli, GI1786641, Length=188, Percent_Identity=54.2553191489362, Blast_Score=223, Evalue=7e-60,
Organism=Caenorhabditis elegans, GI17538017, Length=185, Percent_Identity=48.6486486486487, Blast_Score=186, Evalue=8e-48,
Organism=Drosophila melanogaster, GI20129427, Length=189, Percent_Identity=51.3227513227513, Blast_Score=200, Evalue=5e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001907
- InterPro:   IPR018215 [H]

Pfam domain/function: PF00574 CLP_protease [H]

EC number: =3.4.21.92 [H]

Molecular weight: Translated: 24884; Mature: 24884

Theoretical pI: Translated: 5.88; Mature: 5.88

Prosite motif: PS00382 CLP_PROTEASE_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
5.8 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
5.8 %Met     (Mature Protein)
6.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNYGKEFKNFATKHHGVNAMYYDKIISAMTPTNLTPNIIEERQLNVSILDVFSRLMMDRI
CCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHH
IFLGTGIDDQIANVVQAQLLFLESADASKDIQIYLNSPGGSVYAGLGIYDTMQYIKPDVA
HHHCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCEEECCCHHHHHHHHCCCHH
TICTGMAASMGAVLLCAGAAGKRSALPHSRVMIHQPSGGAQGVATDMEINLREMLKLKDE
HHHHHHHHHHHHHEEECCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHH
LYHIISQHSGQSFERVHKDSERDYWMIADEAKEYGMIDEVLRRG
HHHHHHHCCCCHHHHHHCCCCCCEEEEEHHHHHCCCHHHHHHCC
>Mature Secondary Structure
MNYGKEFKNFATKHHGVNAMYYDKIISAMTPTNLTPNIIEERQLNVSILDVFSRLMMDRI
CCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHH
IFLGTGIDDQIANVVQAQLLFLESADASKDIQIYLNSPGGSVYAGLGIYDTMQYIKPDVA
HHHCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCEEECCCHHHHHHHHCCCHH
TICTGMAASMGAVLLCAGAAGKRSALPHSRVMIHQPSGGAQGVATDMEINLREMLKLKDE
HHHHHHHHHHHHHEEECCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHH
LYHIISQHSGQSFERVHKDSERDYWMIADEAKEYGMIDEVLRRG
HHHHHHHCCCCHHHHHHCCCCCCEEEEEHHHHHCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA