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The map label for this gene is ctaB [H]

Identifier: 146299418

GI number: 146299418

Start: 1928852

End: 1929799

Strand: Direct

Name: ctaB [H]

Synonym: Fjoh_1658

Alternate gene names: 146299418

Gene position: 1928852-1929799 (Clockwise)

Preceding gene: 146299417

Following gene: 146299419

Centisome position: 31.64

GC content: 35.34

Gene sequence:

>948_bases
TTGTACATTTGCAGCACTCAAAAAAAATATACAAAGACTACGGTATTGAACGCTGCTAAAAATACATTATCAATAAAATC
AATATTTCTGGATTTCAAAGAGATTACTAAAGCTGGTTTGGCTATTAGTGTTTTGTTCTCTTCGATAGCAGGATATTTGT
TAGGAGTTAATGACGAACATCCTTTTAAATGGAGTGTTTTAATTGTTTTAGCAATTGGAGGCTATTGTATGGTTGGAGCA
TCTAATGCTTATAATCAGGTAATCGAGAAAGATATCGATTCATTAATGGATCGAACAAAAAATCGCCCTGTTGCTTCTGG
GCGTATGTCAAAAGTAACAGCCTTGATAGTGGCAAGTCTGCTTACTATAATTGGTATTGTTCTTTTGTATACAATCAATG
CTAAGTCGGCAATGTTTGCTGCAATTTCAATATTTTTATATACCAGTATATATACACCATTAAAAACCGTAACTTCATTG
TCGGTTTTTGTTGGTGCTTTCCCGGGCGCAATTCCTTTTATGTTAGGATGGGTTGCGGCAACAGGAGAATTTGGTATTGA
AGCCGGAACGCTTTTTTTAATTCAGTTTTTCTGGCAGTTTCCTCATTTTTGGTCAATTGGATGGTTCTTATATGACGATT
ATGCAAAAGCAGGAATCTTTATGCTTCCAACCGGAAATAAAGACAGAAAAACCGCTTTGCAGGTTATTTTATATACGATT
TGGTTAATAATAGCTTCGTTGTTACCGGTTTTAGGGTATACAGGGCAGTTATTTATTTCGCCGGTCGCGGCAGTTTTAGT
GTTTTTATTAGGTTTATGGATGCTGTTTTATGCAGTTCGTTTATACCAGCTGCGAACACCAAAAGCAGCCAGAACATTAA
TGTTAGTGAGTGTATCGTACATTTCATTACTGCAGATTGTGTTTATAGTAGATAAATTTTTAAGATAG

Upstream 100 bases:

>100_bases
ATTTTTCGAAATAATACTGTTAAAGATTGGCAAGTTCTTATTCTGTAAAGGTTTTATTGAAAAAAATCTAATTTTATAGG
TCTCAATTCTACAATCTAAT

Downstream 100 bases:

>100_bases
TTATGGAAATGACATTAACAACAAGTGATGAGCAGGTAAGAAAATCAAAATCGGCAAAGCTGATTTTGTTGTTCGCAATG
GTTAGTATGACCATGATGTT

Product: protoheme IX farnesyltransferase

Products: NA

Alternate protein names: Heme B farnesyltransferase; Heme O synthase [H]

Number of amino acids: Translated: 315; Mature: 315

Protein sequence:

>315_residues
MYICSTQKKYTKTTVLNAAKNTLSIKSIFLDFKEITKAGLAISVLFSSIAGYLLGVNDEHPFKWSVLIVLAIGGYCMVGA
SNAYNQVIEKDIDSLMDRTKNRPVASGRMSKVTALIVASLLTIIGIVLLYTINAKSAMFAAISIFLYTSIYTPLKTVTSL
SVFVGAFPGAIPFMLGWVAATGEFGIEAGTLFLIQFFWQFPHFWSIGWFLYDDYAKAGIFMLPTGNKDRKTALQVILYTI
WLIIASLLPVLGYTGQLFISPVAAVLVFLLGLWMLFYAVRLYQLRTPKAARTLMLVSVSYISLLQIVFIVDKFLR

Sequences:

>Translated_315_residues
MYICSTQKKYTKTTVLNAAKNTLSIKSIFLDFKEITKAGLAISVLFSSIAGYLLGVNDEHPFKWSVLIVLAIGGYCMVGA
SNAYNQVIEKDIDSLMDRTKNRPVASGRMSKVTALIVASLLTIIGIVLLYTINAKSAMFAAISIFLYTSIYTPLKTVTSL
SVFVGAFPGAIPFMLGWVAATGEFGIEAGTLFLIQFFWQFPHFWSIGWFLYDDYAKAGIFMLPTGNKDRKTALQVILYTI
WLIIASLLPVLGYTGQLFISPVAAVLVFLLGLWMLFYAVRLYQLRTPKAARTLMLVSVSYISLLQIVFIVDKFLR
>Mature_315_residues
MYICSTQKKYTKTTVLNAAKNTLSIKSIFLDFKEITKAGLAISVLFSSIAGYLLGVNDEHPFKWSVLIVLAIGGYCMVGA
SNAYNQVIEKDIDSLMDRTKNRPVASGRMSKVTALIVASLLTIIGIVLLYTINAKSAMFAAISIFLYTSIYTPLKTVTSL
SVFVGAFPGAIPFMLGWVAATGEFGIEAGTLFLIQFFWQFPHFWSIGWFLYDDYAKAGIFMLPTGNKDRKTALQVILYTI
WLIIASLLPVLGYTGQLFISPVAAVLVFLLGLWMLFYAVRLYQLRTPKAARTLMLVSVSYISLLQIVFIVDKFLR

Specific function: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group [H]

COG id: COG0109

COG function: function code O; Polyprenyltransferase (cytochrome oxidase assembly factor)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily [H]

Homologues:

Organism=Homo sapiens, GI17921982, Length=192, Percent_Identity=36.4583333333333, Blast_Score=127, Evalue=1e-29,
Organism=Escherichia coli, GI1786631, Length=288, Percent_Identity=30.9027777777778, Blast_Score=117, Evalue=7e-28,
Organism=Caenorhabditis elegans, GI71998235, Length=280, Percent_Identity=31.7857142857143, Blast_Score=115, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6325085, Length=197, Percent_Identity=31.4720812182741, Blast_Score=100, Evalue=2e-22,
Organism=Drosophila melanogaster, GI19921064, Length=286, Percent_Identity=29.3706293706294, Blast_Score=132, Evalue=4e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006369
- InterPro:   IPR000537 [H]

Pfam domain/function: PF01040 UbiA [H]

EC number: 2.5.1.-

Molecular weight: Translated: 34984; Mature: 34984

Theoretical pI: Translated: 10.00; Mature: 10.00

Prosite motif: PS00943 UBIA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYICSTQKKYTKTTVLNAAKNTLSIKSIFLDFKEITKAGLAISVLFSSIAGYLLGVNDEH
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCC
PFKWSVLIVLAIGGYCMVGASNAYNQVIEKDIDSLMDRTKNRPVASGRMSKVTALIVASL
CCHHHHHHHHHHCCEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
LTIIGIVLLYTINAKSAMFAAISIFLYTSIYTPLKTVTSLSVFVGAFPGAIPFMLGWVAA
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
TGEFGIEAGTLFLIQFFWQFPHFWSIGWFLYDDYAKAGIFMLPTGNKDRKTALQVILYTI
CCCCCCCHHHHHHHHHHHHCCHHHHHHHHEEEHHHHCCEEEECCCCCHHHHHHHHHHHHH
WLIIASLLPVLGYTGQLFISPVAAVLVFLLGLWMLFYAVRLYQLRTPKAARTLMLVSVSY
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
ISLLQIVFIVDKFLR
HHHHHHHHHHHHHCC
>Mature Secondary Structure
MYICSTQKKYTKTTVLNAAKNTLSIKSIFLDFKEITKAGLAISVLFSSIAGYLLGVNDEH
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCC
PFKWSVLIVLAIGGYCMVGASNAYNQVIEKDIDSLMDRTKNRPVASGRMSKVTALIVASL
CCHHHHHHHHHHCCEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
LTIIGIVLLYTINAKSAMFAAISIFLYTSIYTPLKTVTSLSVFVGAFPGAIPFMLGWVAA
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
TGEFGIEAGTLFLIQFFWQFPHFWSIGWFLYDDYAKAGIFMLPTGNKDRKTALQVILYTI
CCCCCCCHHHHHHHHHHHHCCHHHHHHHHEEEHHHHCCEEEECCCCCHHHHHHHHHHHHH
WLIIASLLPVLGYTGQLFISPVAAVLVFLLGLWMLFYAVRLYQLRTPKAARTLMLVSVSY
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
ISLLQIVFIVDKFLR
HHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA