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The map label for this gene is tadA [H]

Identifier: 146299285

GI number: 146299285

Start: 1759966

End: 1760409

Strand: Direct

Name: tadA [H]

Synonym: Fjoh_1525

Alternate gene names: 146299285

Gene position: 1759966-1760409 (Clockwise)

Preceding gene: 146299281

Following gene: 146299286

Centisome position: 28.87

GC content: 39.41

Gene sequence:

>444_bases
ATGATAAATCCTTTCACCGACGAATATTTTATGAAAAAAGCTTTGCAGGAAGCTGAAATCGCTTATGAAAAAGGCGAAAT
TCCTGTAGGAGCCATAATTGTCGTAGCCGATAAAGTAATTGCAAGAAGTCATAACTTGACAGAATTACTAAATGATGTTA
CTGCTCATGCCGAAATGCAGTCGATAACCGCGGCAGCAAATTTTCTTGGCGGAAAATATTTAAAAGATTGTACTTTGTAC
GTAACGCTCGAACCTTGTCAAATGTGTGCCGGTGCTTTGTACTGGAGCCAGATTTCAAAGATTGTTTTTGGCGCACGCGA
CGAACAGCGCGGCTTTATCAATATGGGAACAAAACTGCATCCTAAAACTACAGTTGTTTCTGGTGTAATGGCAAATGAAG
CAGCAGATCTTATGAAACGGTTTTTTCTGGAAAGAAGGAAATAA

Upstream 100 bases:

>100_bases
GTACTGTGTTTTAGCAGCTATTTTATGTTTTCTTTCCATATTCTATTATCACGATTTAAATGTAATAAAAAATAAGTTGT
AAAATCTTATTTTTGCAAGT

Downstream 100 bases:

>100_bases
ATTAAAATAAGTAAGATTTTGTTTATATTTTTGTTGCCAGTGTTAATGATAACAAACAGTATTATAAAAAATCTATGTTA
TTAAAAAATATTTTTCTCTA

Product: zinc-binding CMP/dCMP deaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 147; Mature: 147

Protein sequence:

>147_residues
MINPFTDEYFMKKALQEAEIAYEKGEIPVGAIIVVADKVIARSHNLTELLNDVTAHAEMQSITAAANFLGGKYLKDCTLY
VTLEPCQMCAGALYWSQISKIVFGARDEQRGFINMGTKLHPKTTVVSGVMANEAADLMKRFFLERRK

Sequences:

>Translated_147_residues
MINPFTDEYFMKKALQEAEIAYEKGEIPVGAIIVVADKVIARSHNLTELLNDVTAHAEMQSITAAANFLGGKYLKDCTLY
VTLEPCQMCAGALYWSQISKIVFGARDEQRGFINMGTKLHPKTTVVSGVMANEAADLMKRFFLERRK
>Mature_147_residues
MINPFTDEYFMKKALQEAEIAYEKGEIPVGAIIVVADKVIARSHNLTELLNDVTAHAEMQSITAAANFLGGKYLKDCTLY
VTLEPCQMCAGALYWSQISKIVFGARDEQRGFINMGTKLHPKTTVVSGVMANEAADLMKRFFLERRK

Specific function: Deaminates adenosine-34 to inosine in tRNA-Arg2 [H]

COG id: COG0590

COG function: function code FJ; Cytosine/adenosine deaminases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI124107608, Length=149, Percent_Identity=31.5436241610738, Blast_Score=76, Evalue=1e-14,
Organism=Escherichia coli, GI145693172, Length=149, Percent_Identity=40.2684563758389, Blast_Score=112, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17541138, Length=144, Percent_Identity=33.3333333333333, Blast_Score=83, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17554608, Length=108, Percent_Identity=39.8148148148148, Blast_Score=82, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17555996, Length=110, Percent_Identity=36.3636363636364, Blast_Score=68, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6325319, Length=142, Percent_Identity=33.0985915492958, Blast_Score=71, Evalue=7e-14,
Organism=Saccharomyces cerevisiae, GI6322425, Length=156, Percent_Identity=33.3333333333333, Blast_Score=66, Evalue=2e-12,
Organism=Drosophila melanogaster, GI21355527, Length=142, Percent_Identity=32.3943661971831, Blast_Score=81, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: NA

Molecular weight: Translated: 16409; Mature: 16409

Theoretical pI: Translated: 7.44; Mature: 7.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINPFTDEYFMKKALQEAEIAYEKGEIPVGAIIVVADKVIARSHNLTELLNDVTAHAEMQ
CCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHEEHHHHHHHCCCCHHHHHHHHHHHHHHH
SITAAANFLGGKYLKDCTLYVTLEPCQMCAGALYWSQISKIVFGARDEQRGFINMGTKLH
HHHHHHHHHCCHHHCCEEEEEEECHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCC
PKTTVVSGVMANEAADLMKRFFLERRK
CHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MINPFTDEYFMKKALQEAEIAYEKGEIPVGAIIVVADKVIARSHNLTELLNDVTAHAEMQ
CCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHEEHHHHHHHCCCCHHHHHHHHHHHHHHH
SITAAANFLGGKYLKDCTLYVTLEPCQMCAGALYWSQISKIVFGARDEQRGFINMGTKLH
HHHHHHHHHCCHHHCCEEEEEEECHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCC
PKTTVVSGVMANEAADLMKRFFLERRK
CHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1698458; 7584024; 9384377 [H]