Click here to switch to the map view.

The map label for this gene is sir1 [H]

Identifier: 146299264

GI number: 146299264

Start: 1731705

End: 1733795

Strand: Direct

Name: sir1 [H]

Synonym: Fjoh_1504

Alternate gene names: 146299264

Gene position: 1731705-1733795 (Clockwise)

Preceding gene: 146299263

Following gene: 146299265

Centisome position: 28.4

GC content: 36.68

Gene sequence:

>2091_bases
ATGGAAAGTTTTAGAACAGAAATAGAAAATCCGGTAGTTCAGAAGGAGATTATCGAATTAGAAAAAAAGATTCATTTATT
CCGTGGAGGAAAAATTGATGATGAGCGTTTTCGTAGTCTTCGTTTAGCGCGTGGAATCTACGGTCAGCGTCAGGAAGGCG
TTCAGATGATCCGTATCAAATTGCCTTACGGTAAAGTAACCAGCGAGCAATTGGTGCGTATTACTCAGGTTTCTGACGAA
TATTCTACGGGACGTTTGCACATTACAACACGTCAGGATATCCAGATTCACTATGTGAGTTTAGACAGAACACCGGAACT
TTGGGCAGATTTGGCTAAAGACGATATCACACTTCGTGAAGCTTGTGGAAACACCGTTAGAAATATTACAGGAAGTGAAC
TAGCTGGAGTTGACGTAAACGAACCATTTGATGTTTCGCCTTATGCACACGGACTTTTTCAGTATTTGTTAAGAAACCCA
ATCTGTCAGGAAATGGGACGTAAATTCAAAATTTCGTTCTCGTCTTCAGATGAAGATACTGCTTTGAGTTATTTACACGA
TTTAGGATTTATTCCGAAAATCAAAGATGGACAAAAAGGTTTTAAAATCATGTTTGGTGGAGGTTTAGGATCTCAGCCAG
CACATGCAGAATTGCTTTCGGAGTTTGTTCCCGTAAACGAAATCATCCCAACAGCAGAAGGAATCATTCGTATTTTTGAT
AGATACGGAGAACGTGCTAAAAGAATGAAAGCGCGTATGAAATTCTTAATCAAAGAAATGGGAAGAGATGTTTTCCTTGA
TTTGGTTGAAAAAGAGAAAAAAGCTATCGCTTTTGAAACATACGAAATTGATACAACCGCTTTTGACGGATCAATTCCAG
AACCAGTTTTAGAAGTTCCGCAAGTTACAATCGAAGATACAGAAGCGTATGAAGCGTGGAAAAAATCGAATGTAATCAAA
CAGAAACAAGACGGTTATTATGCTATTGGAATTAAAGTTTTATTAGGAGATTTTTATACTGATAAAGCGCGATTATTAGC
TGCTTTAATTAAGAATTACGCAGCAAATGAATTACGTTTTTCATTGCGTCAAAATATTGTAATACGTCACGTAAAAGAAG
AAAATTTACCATTCTTTTACCAAGAATTAGCCAAATTGGATTTTGTTCAGTTAGGATATAATTCGGTTGGAGATATTACG
GCATGTCCGGGTACTGATACTTGCAACTTGGGGATTGCAAGTAGTACCGGTATTGCAGAAGAATTAGAAAGAGTTTTAAG
TGCAGAATATCCTCAGTATTTAAACAACCGCGAAATCGAAATTAAAATTTCAGGCTGTATGAATGCCTGCGGACAACATA
ATATGTCTGCAATTGGATTCCAAGGAATGTCTATCAATTCAGGAAAACTAGTAGCTCCGGCTTTACAAGTTTTATTGGGT
GGGGGAAGATTAGGAAATGGCGCAGGACGTTTTGCTGATAAAGTAATCAAAGTACCGAGTCGTAGAGGTCCAGATGCGTT
GCGTACCATCTTAAATGATTTTGATGCTAACGGAAGCGGACAAAAATTCCTTGATTATTATGATACAAAAGGAGAAAAGT
ATTTTTACGAAATCTTAAAACCTTACGCAGATGTAACCAATTTAACAGAAGCAGATTTTGTAGATTGGGGTAATGCAGAC
AATTACGTAAAAGCAGTTGGAGTTGGAGAATGTGCTGGAGTTGTAATCGATTTAGTAGCGACATTATTGTTTGAAGCTAA
AGAGAAATTGATTTTGGCTCAGGAATCTTTCGATGAGAAAAAATGGTCAGATGCAATTTACCATGCTTACGCTGGATTTG
TAAATGGAGCAAAAGCTTTATTGTTGTCAGAAAACCAAAAAACAAACCATCACGCAGGAATCGTGGATTTGTTTGATACT
GTTTTTATCGACACGAATAAAATAGAATTAAACTCAACTTTTAAAGATTTGGTTTACCAAATCAATAAAAATGAACCATC
TGAAGCTTTCGCTAAAGATTACATTGCTCAGGCAACTGTTTTCTTTGATAAAATCGAAACTTTCAGAGCTCAGGAATTAG
AAAATGCTTAA

Upstream 100 bases:

>100_bases
TATAAGCTTTAAGCAATAAGCCTTAAGCTTAAAAGATTGAAGACACAAAGTTTAAAAAGCTTATAGCCTACAGCTTAAAG
CCTAAAGCAAGAAAAAGAAA

Downstream 100 bases:

>100_bases
TATAAAACCCAAAATAACTTTAGTCGGTGCAGGTCCGGGCGATCCCGATTTACTGACGCTAAAAGCTGTAAAGGCATTGG
CTGAAGCAAATGTGGTTTTA

Product: sulfite reductase (ferredoxin)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 696; Mature: 696

Protein sequence:

>696_residues
MESFRTEIENPVVQKEIIELEKKIHLFRGGKIDDERFRSLRLARGIYGQRQEGVQMIRIKLPYGKVTSEQLVRITQVSDE
YSTGRLHITTRQDIQIHYVSLDRTPELWADLAKDDITLREACGNTVRNITGSELAGVDVNEPFDVSPYAHGLFQYLLRNP
ICQEMGRKFKISFSSSDEDTALSYLHDLGFIPKIKDGQKGFKIMFGGGLGSQPAHAELLSEFVPVNEIIPTAEGIIRIFD
RYGERAKRMKARMKFLIKEMGRDVFLDLVEKEKKAIAFETYEIDTTAFDGSIPEPVLEVPQVTIEDTEAYEAWKKSNVIK
QKQDGYYAIGIKVLLGDFYTDKARLLAALIKNYAANELRFSLRQNIVIRHVKEENLPFFYQELAKLDFVQLGYNSVGDIT
ACPGTDTCNLGIASSTGIAEELERVLSAEYPQYLNNREIEIKISGCMNACGQHNMSAIGFQGMSINSGKLVAPALQVLLG
GGRLGNGAGRFADKVIKVPSRRGPDALRTILNDFDANGSGQKFLDYYDTKGEKYFYEILKPYADVTNLTEADFVDWGNAD
NYVKAVGVGECAGVVIDLVATLLFEAKEKLILAQESFDEKKWSDAIYHAYAGFVNGAKALLLSENQKTNHHAGIVDLFDT
VFIDTNKIELNSTFKDLVYQINKNEPSEAFAKDYIAQATVFFDKIETFRAQELENA

Sequences:

>Translated_696_residues
MESFRTEIENPVVQKEIIELEKKIHLFRGGKIDDERFRSLRLARGIYGQRQEGVQMIRIKLPYGKVTSEQLVRITQVSDE
YSTGRLHITTRQDIQIHYVSLDRTPELWADLAKDDITLREACGNTVRNITGSELAGVDVNEPFDVSPYAHGLFQYLLRNP
ICQEMGRKFKISFSSSDEDTALSYLHDLGFIPKIKDGQKGFKIMFGGGLGSQPAHAELLSEFVPVNEIIPTAEGIIRIFD
RYGERAKRMKARMKFLIKEMGRDVFLDLVEKEKKAIAFETYEIDTTAFDGSIPEPVLEVPQVTIEDTEAYEAWKKSNVIK
QKQDGYYAIGIKVLLGDFYTDKARLLAALIKNYAANELRFSLRQNIVIRHVKEENLPFFYQELAKLDFVQLGYNSVGDIT
ACPGTDTCNLGIASSTGIAEELERVLSAEYPQYLNNREIEIKISGCMNACGQHNMSAIGFQGMSINSGKLVAPALQVLLG
GGRLGNGAGRFADKVIKVPSRRGPDALRTILNDFDANGSGQKFLDYYDTKGEKYFYEILKPYADVTNLTEADFVDWGNAD
NYVKAVGVGECAGVVIDLVATLLFEAKEKLILAQESFDEKKWSDAIYHAYAGFVNGAKALLLSENQKTNHHAGIVDLFDT
VFIDTNKIELNSTFKDLVYQINKNEPSEAFAKDYIAQATVFFDKIETFRAQELENA
>Mature_696_residues
MESFRTEIENPVVQKEIIELEKKIHLFRGGKIDDERFRSLRLARGIYGQRQEGVQMIRIKLPYGKVTSEQLVRITQVSDE
YSTGRLHITTRQDIQIHYVSLDRTPELWADLAKDDITLREACGNTVRNITGSELAGVDVNEPFDVSPYAHGLFQYLLRNP
ICQEMGRKFKISFSSSDEDTALSYLHDLGFIPKIKDGQKGFKIMFGGGLGSQPAHAELLSEFVPVNEIIPTAEGIIRIFD
RYGERAKRMKARMKFLIKEMGRDVFLDLVEKEKKAIAFETYEIDTTAFDGSIPEPVLEVPQVTIEDTEAYEAWKKSNVIK
QKQDGYYAIGIKVLLGDFYTDKARLLAALIKNYAANELRFSLRQNIVIRHVKEENLPFFYQELAKLDFVQLGYNSVGDIT
ACPGTDTCNLGIASSTGIAEELERVLSAEYPQYLNNREIEIKISGCMNACGQHNMSAIGFQGMSINSGKLVAPALQVLLG
GGRLGNGAGRFADKVIKVPSRRGPDALRTILNDFDANGSGQKFLDYYDTKGEKYFYEILKPYADVTNLTEADFVDWGNAD
NYVKAVGVGECAGVVIDLVATLLFEAKEKLILAQESFDEKKWSDAIYHAYAGFVNGAKALLLSENQKTNHHAGIVDLFDT
VFIDTNKIELNSTFKDLVYQINKNEPSEAFAKDYIAQATVFFDKIETFRAQELENA

Specific function: This Enzyme Catalyzes The 6-Electron Reduction Of Sulfite To Sulfide. This Is One Of Several Activities Required For The Biosynthesis Of L-Cysteine From Sulfate. [C]

COG id: COG0155

COG function: function code P; Sulfite reductase, beta subunit (hemoprotein)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nitrite and sulfite reductase 4Fe-4S domain family [H]

Homologues:

None

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005117
- InterPro:   IPR006067
- InterPro:   IPR006066 [H]

Pfam domain/function: PF01077 NIR_SIR; PF03460 NIR_SIR_ferr [H]

EC number: =1.8.7.1 [H]

Molecular weight: Translated: 78217; Mature: 78217

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESFRTEIENPVVQKEIIELEKKIHLFRGGKIDDERFRSLRLARGIYGQRQEGVQMIRIK
CCCHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEEE
LPYGKVTSEQLVRITQVSDEYSTGRLHITTRQDIQIHYVSLDRTPELWADLAKDDITLRE
CCCCCCCHHHHHHHHHCCCCCCCCEEEEEECCCEEEEEEEECCCHHHHHHHHHCCCHHHH
ACGNTVRNITGSELAGVDVNEPFDVSPYAHGLFQYLLRNPICQEMGRKFKISFSSSDEDT
HCCHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHCCCEEEEEECCCCCHH
ALSYLHDLGFIPKIKDGQKGFKIMFGGGLGSQPAHAELLSEFVPVNEIIPTAEGIIRIFD
HHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHCCHHHHCCCHHHHHHHHH
RYGERAKRMKARMKFLIKEMGRDVFLDLVEKEKKAIAFETYEIDTTAFDGSIPEPVLEVP
HHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHEEEEEEEEEECEECCCCCCCHHHHCC
QVTIEDTEAYEAWKKSNVIKQKQDGYYAIGIKVLLGDFYTDKARLLAALIKNYAANELRF
CEEECCCHHHHHHHHCCCHHHCCCCEEEEEEEEECCHHCCHHHHHHHHHHHHHHHHHHHH
SLRQNIVIRHVKEENLPFFYQELAKLDFVQLGYNSVGDITACPGTDTCNLGIASSTGIAE
HHHHHHHEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCCCCCCCCCHHH
ELERVLSAEYPQYLNNREIEIKISGCMNACGQHNMSAIGFQGMSINSGKLVAPALQVLLG
HHHHHHHHCCHHHHCCCEEEEEEHHHHHHCCCCCCCEEEECCCCCCCCCHHHHHHHHHHC
GGRLGNGAGRFADKVIKVPSRRGPDALRTILNDFDANGSGQKFLDYYDTKGEKYFYEILK
CCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHCCCCHHHHHHHHH
PYADVTNLTEADFVDWGNADNYVKAVGVGECAGVVIDLVATLLFEAKEKLILAQESFDEK
HHHHHCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHEEEEHHHCCHH
KWSDAIYHAYAGFVNGAKALLLSENQKTNHHAGIVDLFDTVFIDTNKIELNSTFKDLVYQ
HHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCHHHHHHHHEEECCEEEECCHHHHHHHH
INKNEPSEAFAKDYIAQATVFFDKIETFRAQELENA
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MESFRTEIENPVVQKEIIELEKKIHLFRGGKIDDERFRSLRLARGIYGQRQEGVQMIRIK
CCCHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEEE
LPYGKVTSEQLVRITQVSDEYSTGRLHITTRQDIQIHYVSLDRTPELWADLAKDDITLRE
CCCCCCCHHHHHHHHHCCCCCCCCEEEEEECCCEEEEEEEECCCHHHHHHHHHCCCHHHH
ACGNTVRNITGSELAGVDVNEPFDVSPYAHGLFQYLLRNPICQEMGRKFKISFSSSDEDT
HCCHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHCCCEEEEEECCCCCHH
ALSYLHDLGFIPKIKDGQKGFKIMFGGGLGSQPAHAELLSEFVPVNEIIPTAEGIIRIFD
HHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHCCHHHHCCCHHHHHHHHH
RYGERAKRMKARMKFLIKEMGRDVFLDLVEKEKKAIAFETYEIDTTAFDGSIPEPVLEVP
HHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHEEEEEEEEEECEECCCCCCCHHHHCC
QVTIEDTEAYEAWKKSNVIKQKQDGYYAIGIKVLLGDFYTDKARLLAALIKNYAANELRF
CEEECCCHHHHHHHHCCCHHHCCCCEEEEEEEEECCHHCCHHHHHHHHHHHHHHHHHHHH
SLRQNIVIRHVKEENLPFFYQELAKLDFVQLGYNSVGDITACPGTDTCNLGIASSTGIAE
HHHHHHHEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCCCCCCCCCHHH
ELERVLSAEYPQYLNNREIEIKISGCMNACGQHNMSAIGFQGMSINSGKLVAPALQVLLG
HHHHHHHHCCHHHHCCCEEEEEEHHHHHHCCCCCCCEEEECCCCCCCCCHHHHHHHHHHC
GGRLGNGAGRFADKVIKVPSRRGPDALRTILNDFDANGSGQKFLDYYDTKGEKYFYEILK
CCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHCCCCHHHHHHHHH
PYADVTNLTEADFVDWGNADNYVKAVGVGECAGVVIDLVATLLFEAKEKLILAQESFDEK
HHHHHCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHEEEEHHHCCHH
KWSDAIYHAYAGFVNGAKALLLSENQKTNHHAGIVDLFDTVFIDTNKIELNSTFKDLVYQ
HHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCHHHHHHHHEEECCEEEECCHHHHHHHH
INKNEPSEAFAKDYIAQATVFFDKIETFRAQELENA
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA