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The map label for this gene is cysH [H]

Identifier: 146299261

GI number: 146299261

Start: 1728362

End: 1729072

Strand: Direct

Name: cysH [H]

Synonym: Fjoh_1501

Alternate gene names: 146299261

Gene position: 1728362-1729072 (Clockwise)

Preceding gene: 146299260

Following gene: 146299262

Centisome position: 28.35

GC content: 35.3

Gene sequence:

>711_bases
ATGAGTGCGATTATTGTACAAGAATTATTAGAGAAAACGAAAGATTTCTCACTTGACGAAACCTTAGTTTTTTTAGCAGA
AGAATTTCCGGGAAAAGTAATTTTTTCGACTTCTTTTGGGCAGGAAGATCAGGTAATTACTGATTTTATTGCAAAAAGTA
ACACAGATATTACTGTTTTTACTTTAGACACAGGAAGATTATTTCAGGAAACGTATGACGTTTTTCACAAAACATTAAAA
AAGTATAAAAGACCAATTGAGGTTTATTTTCCAGAAGCGGCGGCTGTAGAAAATTTACTAAAATCAAAAGGACCAAACAG
CTTTTACGATTCAGTTGAAAACAGAAAAGAATGCTGTTTTATTCGAAAAGTGGTTCCGTTGAGAAAAGCTTTATCAGGAA
ACGCAGTTTGGATTACTGGTTTAAGAGCAGAACAATCAGAAAACAGACAAGATCTAAACTTGTTTGAATACGACGGAAAC
TTCGAAATCATCAAATTTAATCCGTTATTAAAATGGACTTTAGAAGAAGTTGAAACGTATTTGTCAGAAAATAATGTTCC
TCAAAACGCTTTACACAAACAAGGTTTCGTAAGTATTGGATGTGCGCCTTGTACGAGAGCGATTTTCCCTGGAGAAGATA
TCAGAGCCGGAAGATGGTGGTGGGAGTCAAGCCATAAAGAGTGCGGGCTTCACAGTGCGAAAAAAGAGTAA

Upstream 100 bases:

>100_bases
AGAAAACCAATGATGGTTGCTGTTGGAGTTCTAATTATATTATTGAGTTTAAAAACATTATCTAAATTATTATAATTCTT
TAGATAGGGAGAAAGAGATT

Downstream 100 bases:

>100_bases
GTAGAAGAAAGAAGCAATAGCAAAGAAAATAGATTTAAAGTTCCGAAGGAACGATTCATATTGTAGCGCCGGATTTTAAT
CCGGGGGGAGAGGTGATAAA

Product: adenylylsulfate reductase, thioredoxin dependent

Products: NA

Alternate protein names: 3'-phosphoadenylylsulfate reductase; PAPS reductase, thioredoxin dependent; PAPS sulfotransferase; PAdoPS reductase [H]

Number of amino acids: Translated: 236; Mature: 235

Protein sequence:

>236_residues
MSAIIVQELLEKTKDFSLDETLVFLAEEFPGKVIFSTSFGQEDQVITDFIAKSNTDITVFTLDTGRLFQETYDVFHKTLK
KYKRPIEVYFPEAAAVENLLKSKGPNSFYDSVENRKECCFIRKVVPLRKALSGNAVWITGLRAEQSENRQDLNLFEYDGN
FEIIKFNPLLKWTLEEVETYLSENNVPQNALHKQGFVSIGCAPCTRAIFPGEDIRAGRWWWESSHKECGLHSAKKE

Sequences:

>Translated_236_residues
MSAIIVQELLEKTKDFSLDETLVFLAEEFPGKVIFSTSFGQEDQVITDFIAKSNTDITVFTLDTGRLFQETYDVFHKTLK
KYKRPIEVYFPEAAAVENLLKSKGPNSFYDSVENRKECCFIRKVVPLRKALSGNAVWITGLRAEQSENRQDLNLFEYDGN
FEIIKFNPLLKWTLEEVETYLSENNVPQNALHKQGFVSIGCAPCTRAIFPGEDIRAGRWWWESSHKECGLHSAKKE
>Mature_235_residues
SAIIVQELLEKTKDFSLDETLVFLAEEFPGKVIFSTSFGQEDQVITDFIAKSNTDITVFTLDTGRLFQETYDVFHKTLKK
YKRPIEVYFPEAAAVENLLKSKGPNSFYDSVENRKECCFIRKVVPLRKALSGNAVWITGLRAEQSENRQDLNLFEYDGNF
EIIKFNPLLKWTLEEVETYLSENNVPQNALHKQGFVSIGCAPCTRAIFPGEDIRAGRWWWESSHKECGLHSAKKE

Specific function: Reduction of activated sulfate into sulfite [H]

COG id: COG0175

COG function: function code EH; 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PAPS reductase family. CysH subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789121, Length=211, Percent_Identity=29.3838862559242, Blast_Score=84, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6325425, Length=210, Percent_Identity=33.3333333333333, Blast_Score=99, Evalue=8e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011798
- InterPro:   IPR004511
- InterPro:   IPR002500
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01507 PAPS_reduct [H]

EC number: =1.8.4.8 [H]

Molecular weight: Translated: 27105; Mature: 26974

Theoretical pI: Translated: 5.22; Mature: 5.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
0.4 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAIIVQELLEKTKDFSLDETLVFLAEEFPGKVIFSTSFGQEDQVITDFIAKSNTDITVF
CCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHCCCCCEEEE
TLDTGRLFQETYDVFHKTLKKYKRPIEVYFPEAAAVENLLKSKGPNSFYDSVENRKECCF
EECCCHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHCCCCCHHHHHHHHHHHHHH
IRKVVPLRKALSGNAVWITGLRAEQSENRQDLNLFEYDGNFEIIKFNPLLKWTLEEVETY
HHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCEEEEECCCEEEEEECCHHHHHHHHHHHH
LSENNVPQNALHKQGFVSIGCAPCTRAIFPGEDIRAGRWWWESSHKECGLHSAKKE
HHCCCCCHHHHHHCCCEEECCHHHHCCCCCCCCCCCCCCEECCCCCCCCCCCCCCC
>Mature Secondary Structure 
SAIIVQELLEKTKDFSLDETLVFLAEEFPGKVIFSTSFGQEDQVITDFIAKSNTDITVF
CHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHCCCCCEEEE
TLDTGRLFQETYDVFHKTLKKYKRPIEVYFPEAAAVENLLKSKGPNSFYDSVENRKECCF
EECCCHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHCCCCCHHHHHHHHHHHHHH
IRKVVPLRKALSGNAVWITGLRAEQSENRQDLNLFEYDGNFEIIKFNPLLKWTLEEVETY
HHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCEEEEECCCEEEEEECCHHHHHHHHHHHH
LSENNVPQNALHKQGFVSIGCAPCTRAIFPGEDIRAGRWWWESSHKECGLHSAKKE
HHCCCCCHHHHHHCCCEEECCHHHHCCCCCCCCCCCCCCEECCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194 [H]