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The map label for this gene is dtpA [H]

Identifier: 146299181

GI number: 146299181

Start: 1630826

End: 1632310

Strand: Direct

Name: dtpA [H]

Synonym: Fjoh_1421

Alternate gene names: 146299181

Gene position: 1630826-1632310 (Clockwise)

Preceding gene: 146299180

Following gene: 146299182

Centisome position: 26.75

GC content: 33.8

Gene sequence:

>1485_bases
ATGGAAAACAATATTACTTTAGAAGAAATTCAAAATTTTAAAGGCAAGTACCCAAAACAATTGTGGTACTTGTTTTTGGT
TGAAATGTGGGAACGTTTTTGTTTCTACGGAATGCGTGGTGTTTTAGCTTTCTTTATGGTAGACCAATTAGGTCTGGTGG
AAGGAAAAGCAAATTTGCAATATGGAGCAATTCAGGCTTTTGTATATGCATTTACTTTTATCGGTGGAATTTTTGCTGAT
AAAATACTAGGCTTTAAGAAATCGCTTCTTTTTGGAGGTATCGTCATGATTTTGGGGAACTTGCTTATTGCAGCTTCGCC
GCATGATTTCTTTTATTACGGAATAACACTTTCTATTATTGGGACAGGTTTTTTTAAGCCGAATGTTTCTTCAATGGTAG
GTGAGTTGTATCATGAAAATGATGGCCGCCGTGATGCTGGTTACGGATTATTTTATGCAGGAATTAATATAGGAGGAATG
CTTGGAGGAGCGATTCCTATTTATTTAGGAAAGAACTATTCTTGGAGTCTTTGTTTTCTTTCTGCAGCAATTGTAATGAT
TATTGGTGTTATAACTTTTCTTTTAACAAAAAAGCATTTAGCGCCAATTGGGAATTCTCCATTAGAAAATCATACGCCTA
AAAAACGTAATCTTTATGAGATCGCGGTATATGTAGGTTCTTTTATTGTTATTCCATTAGTTTATATAATGGTAATCAAC
TCTGATTTTACGGAGTATTTCATGTATACAATTGGAGCAGCGGCAGTAGGATATTTTCTATTTGAATTGATACAAATAAA
AGACTCTAAACAACAACGCAAACTTTTAGCGGCATTTGTATTTATTTTTGGATACTTTATGTTTATGGCAATCTCAGAGC
AGTCTGGAGGGTCATTATCGTTGTTTGCTAAAGATAACTTAACAAATAAATTGTTATTCTTCAATATTGATCCAAACGTG
GTAAATAATAGTATAAACTCGCTTTATGTTATTATTTTCAGCCCATTAGTAGGATTGTTGTGGATTTTCCTTTACAAGCG
AAAAATTGAACCAAATACTGTTATTAAATTTGGTTTGTCATTTATCTTGCTTGCGGCTGGTTTCTTCATTTTTTACAGTG
CCAGATTTTTTGTTGATGCAAATGGGTTGAGCTCTCTTGATGTATTTGCTTTAGGGTATCTTTTGTATACACTTGGGGAA
TTATGTATTGGACCAATCGGGATGTCTGTAATTACAAAATTGTCTCCTAAACGTTTGTTTGGAATGATGATGGGATTATG
GTTTTTATCGAGTGCGTTCGGGCAGTTTGCAGCAGGAAAATTAGGCGCTGAAATGTCTGATGCCAATACAGGAACTACGT
TAATGTCTAAACTTATTGCTTATACAGACGGATATTATCAATTAGCATTATATTCTTTAATTGCGGGTGTTGTCTTAATT
ATTACAACGCCGTTAATTAGAAGATTAATGCAGGAAGTAAAATAA

Upstream 100 bases:

>100_bases
TTATGGTTTTTGTTGTTCTGACAGGTATTGCGGCAATTTTATTATTTGCTTTAACACCACTATTGAAAAAATTAATGCAC
GGTGTTAGATAAAATATAAA

Downstream 100 bases:

>100_bases
GCAGAAACTGTTTTTTCAATACATTTTTTGTTTAAATTTGCGAAAAATAATACATTATGAAAAGAATATTATTAATAGCC
TTTTTTGTAGTTGGAGCATT

Product: amino acid/peptide transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 494; Mature: 494

Protein sequence:

>494_residues
MENNITLEEIQNFKGKYPKQLWYLFLVEMWERFCFYGMRGVLAFFMVDQLGLVEGKANLQYGAIQAFVYAFTFIGGIFAD
KILGFKKSLLFGGIVMILGNLLIAASPHDFFYYGITLSIIGTGFFKPNVSSMVGELYHENDGRRDAGYGLFYAGINIGGM
LGGAIPIYLGKNYSWSLCFLSAAIVMIIGVITFLLTKKHLAPIGNSPLENHTPKKRNLYEIAVYVGSFIVIPLVYIMVIN
SDFTEYFMYTIGAAAVGYFLFELIQIKDSKQQRKLLAAFVFIFGYFMFMAISEQSGGSLSLFAKDNLTNKLLFFNIDPNV
VNNSINSLYVIIFSPLVGLLWIFLYKRKIEPNTVIKFGLSFILLAAGFFIFYSARFFVDANGLSSLDVFALGYLLYTLGE
LCIGPIGMSVITKLSPKRLFGMMMGLWFLSSAFGQFAAGKLGAEMSDANTGTTLMSKLIAYTDGYYQLALYSLIAGVVLI
ITTPLIRRLMQEVK

Sequences:

>Translated_494_residues
MENNITLEEIQNFKGKYPKQLWYLFLVEMWERFCFYGMRGVLAFFMVDQLGLVEGKANLQYGAIQAFVYAFTFIGGIFAD
KILGFKKSLLFGGIVMILGNLLIAASPHDFFYYGITLSIIGTGFFKPNVSSMVGELYHENDGRRDAGYGLFYAGINIGGM
LGGAIPIYLGKNYSWSLCFLSAAIVMIIGVITFLLTKKHLAPIGNSPLENHTPKKRNLYEIAVYVGSFIVIPLVYIMVIN
SDFTEYFMYTIGAAAVGYFLFELIQIKDSKQQRKLLAAFVFIFGYFMFMAISEQSGGSLSLFAKDNLTNKLLFFNIDPNV
VNNSINSLYVIIFSPLVGLLWIFLYKRKIEPNTVIKFGLSFILLAAGFFIFYSARFFVDANGLSSLDVFALGYLLYTLGE
LCIGPIGMSVITKLSPKRLFGMMMGLWFLSSAFGQFAAGKLGAEMSDANTGTTLMSKLIAYTDGYYQLALYSLIAGVVLI
ITTPLIRRLMQEVK
>Mature_494_residues
MENNITLEEIQNFKGKYPKQLWYLFLVEMWERFCFYGMRGVLAFFMVDQLGLVEGKANLQYGAIQAFVYAFTFIGGIFAD
KILGFKKSLLFGGIVMILGNLLIAASPHDFFYYGITLSIIGTGFFKPNVSSMVGELYHENDGRRDAGYGLFYAGINIGGM
LGGAIPIYLGKNYSWSLCFLSAAIVMIIGVITFLLTKKHLAPIGNSPLENHTPKKRNLYEIAVYVGSFIVIPLVYIMVIN
SDFTEYFMYTIGAAAVGYFLFELIQIKDSKQQRKLLAAFVFIFGYFMFMAISEQSGGSLSLFAKDNLTNKLLFFNIDPNV
VNNSINSLYVIIFSPLVGLLWIFLYKRKIEPNTVIKFGLSFILLAAGFFIFYSARFFVDANGLSSLDVFALGYLLYTLGE
LCIGPIGMSVITKLSPKRLFGMMMGLWFLSSAFGQFAAGKLGAEMSDANTGTTLMSKLIAYTDGYYQLALYSLIAGVVLI
ITTPLIRRLMQEVK

Specific function: Proton-dependent permease that transports di- and tripeptides [H]

COG id: COG3104

COG function: function code E; Dipeptide/tripeptide permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PTR2/POT transporter (TC 2.A.17) family. DtpA subfamily [H]

Homologues:

Organism=Homo sapiens, GI4827008, Length=220, Percent_Identity=26.3636363636364, Blast_Score=69, Evalue=9e-12,
Organism=Homo sapiens, GI226371746, Length=343, Percent_Identity=25.0728862973761, Blast_Score=67, Evalue=4e-11,
Organism=Escherichia coli, GI1787922, Length=492, Percent_Identity=27.4390243902439, Blast_Score=216, Evalue=4e-57,
Organism=Escherichia coli, GI1789911, Length=478, Percent_Identity=27.6150627615063, Blast_Score=204, Evalue=9e-54,
Organism=Escherichia coli, GI1786927, Length=448, Percent_Identity=28.5714285714286, Blast_Score=182, Evalue=6e-47,
Organism=Escherichia coli, GI1790572, Length=485, Percent_Identity=27.8350515463918, Blast_Score=178, Evalue=7e-46,
Organism=Caenorhabditis elegans, GI71987453, Length=373, Percent_Identity=26.0053619302949, Blast_Score=78, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17569141, Length=352, Percent_Identity=25.2840909090909, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI28571098, Length=223, Percent_Identity=30.4932735426009, Blast_Score=86, Evalue=5e-17,
Organism=Drosophila melanogaster, GI28571102, Length=222, Percent_Identity=30.6306306306306, Blast_Score=86, Evalue=7e-17,
Organism=Drosophila melanogaster, GI28571100, Length=222, Percent_Identity=30.6306306306306, Blast_Score=86, Evalue=7e-17,
Organism=Drosophila melanogaster, GI24639585, Length=209, Percent_Identity=31.5789473684211, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24639583, Length=209, Percent_Identity=31.5789473684211, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24639581, Length=209, Percent_Identity=31.5789473684211, Blast_Score=78, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016196
- InterPro:   IPR000109
- InterPro:   IPR005279
- InterPro:   IPR018456 [H]

Pfam domain/function: PF00854 PTR2 [H]

EC number: NA

Molecular weight: Translated: 55169; Mature: 55169

Theoretical pI: Translated: 9.19; Mature: 9.19

Prosite motif: PS01023 PTR2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENNITLEEIQNFKGKYPKQLWYLFLVEMWERFCFYGMRGVLAFFMVDQLGLVEGKANLQ
CCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
YGAIQAFVYAFTFIGGIFADKILGFKKSLLFGGIVMILGNLLIAASPHDFFYYGITLSII
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCEEEEEEEEEEH
GTGFFKPNVSSMVGELYHENDGRRDAGYGLFYAGINIGGMLGGAIPIYLGKNYSWSLCFL
CCCCCCCCHHHHHHHHHHCCCCCCCCCCEEEEECCCHHHHHCCCEEEEECCCCCHHHHHH
SAAIVMIIGVITFLLTKKHLAPIGNSPLENHTPKKRNLYEIAVYVGSFIVIPLVYIMVIN
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHC
SDFTEYFMYTIGAAAVGYFLFELIQIKDSKQQRKLLAAFVFIFGYFMFMAISEQSGGSLS
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEE
LFAKDNLTNKLLFFNIDPNVVNNSINSLYVIIFSPLVGLLWIFLYKRKIEPNTVIKFGLS
EEEECCCCCEEEEEECCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
FILLAAGFFIFYSARFFVDANGLSSLDVFALGYLLYTLGELCIGPIGMSVITKLSPKRLF
HHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
GMMMGLWFLSSAFGQFAAGKLGAEMSDANTGTTLMSKLIAYTDGYYQLALYSLIAGVVLI
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
ITTPLIRRLMQEVK
HHHHHHHHHHHHCC
>Mature Secondary Structure
MENNITLEEIQNFKGKYPKQLWYLFLVEMWERFCFYGMRGVLAFFMVDQLGLVEGKANLQ
CCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
YGAIQAFVYAFTFIGGIFADKILGFKKSLLFGGIVMILGNLLIAASPHDFFYYGITLSII
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCEEEEEEEEEEH
GTGFFKPNVSSMVGELYHENDGRRDAGYGLFYAGINIGGMLGGAIPIYLGKNYSWSLCFL
CCCCCCCCHHHHHHHHHHCCCCCCCCCCEEEEECCCHHHHHCCCEEEEECCCCCHHHHHH
SAAIVMIIGVITFLLTKKHLAPIGNSPLENHTPKKRNLYEIAVYVGSFIVIPLVYIMVIN
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHC
SDFTEYFMYTIGAAAVGYFLFELIQIKDSKQQRKLLAAFVFIFGYFMFMAISEQSGGSLS
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEE
LFAKDNLTNKLLFFNIDPNVVNNSINSLYVIIFSPLVGLLWIFLYKRKIEPNTVIKFGLS
EEEECCCCCEEEEEECCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
FILLAAGFFIFYSARFFVDANGLSSLDVFALGYLLYTLGELCIGPIGMSVITKLSPKRLF
HHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
GMMMGLWFLSSAFGQFAAGKLGAEMSDANTGTTLMSKLIAYTDGYYQLALYSLIAGVVLI
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
ITTPLIRRLMQEVK
HHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA