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The map label for this gene is coaX

Identifier: 146299171

GI number: 146299171

Start: 1617439

End: 1618173

Strand: Direct

Name: coaX

Synonym: Fjoh_1411

Alternate gene names: 146299171

Gene position: 1617439-1618173 (Clockwise)

Preceding gene: 146299170

Following gene: 146299172

Centisome position: 26.53

GC content: 35.78

Gene sequence:

>735_bases
ATGATTTTAACTGTCGATGTTGGAAATACCAGAATTAAAGCTGCTGTCTTTGAAGGGAGTAGTGTTTTGGAGTATTTCGT
TTTTGAAAAAAATGAGCTTGAAAAAAGAATTGAAAAAATTTTAGAAAAATTTCCAAACTGCTCAGATTTGGTTGTTGCCT
CGGTTGGAGATGTCGAAAAACAATCTTTTTTGAGTTTTGAAAAACAGTTAAATGTTCATTTTTTTACACACGAAGATATT
TTCCCGTTTCATAATAAATATGCAACACCAAAAACTTTAGGAATCGACAGAATGATTTTGGCTGCCGGAGCAACACTGCA
GTTTCCGAAACAAAATCGATTAGTTATAGATGCCGGAACCTGCATTACCTACGATTTTATCGACGAAAACGATAATTATC
TGGGCGGTGCAATCTCTCCAGGGCTTCGTTTGCGTTACGAAACCTTACACAATTACACAGCCAGACTCCCTTTGCTTACT
TTAGATCAGCCCCATTCTTACATTGGAGATTCAACCGCACAGGCGATTCATTCTGGTGTTGTGAATGGTTTCGTCTATGA
GATTGACGGTTTTATCGATGAATATCGCTCGAACTTTTCAAATTTTATAATAATTTTAACGGGAGGCGATGCAGAATTTT
TGGCTAAACGATTAAAAAATACCATATTTGCCAATTCAAATTTCCTTCTGGAGAGTTTGAGCCAAACATATCAATATAAA
ATCGACAATGATTAA

Upstream 100 bases:

>100_bases
TTGTGCTCAATGCGGGTGCAAAGATAGAATCATTTTCCGTTTATCCAAAACATTTTAGAAAAAAAATCAATTCGTATCTT
CGCAAAAACAAAAAAGAAAA

Downstream 100 bases:

>100_bases
AAAAATTATAATAAGTGCTTGTTTGCTTATATCGTTCGTTTCATTTGCTCAGCAAGGTACTGCATCGCCATATTCTTTTT
ATGGAATTGGAGATATCAAG

Product: pantothenate kinase

Products: NA

Alternate protein names: PanK-III; Pantothenic acid kinase

Number of amino acids: Translated: 244; Mature: 244

Protein sequence:

>244_residues
MILTVDVGNTRIKAAVFEGSSVLEYFVFEKNELEKRIEKILEKFPNCSDLVVASVGDVEKQSFLSFEKQLNVHFFTHEDI
FPFHNKYATPKTLGIDRMILAAGATLQFPKQNRLVIDAGTCITYDFIDENDNYLGGAISPGLRLRYETLHNYTARLPLLT
LDQPHSYIGDSTAQAIHSGVVNGFVYEIDGFIDEYRSNFSNFIIILTGGDAEFLAKRLKNTIFANSNFLLESLSQTYQYK
IDND

Sequences:

>Translated_244_residues
MILTVDVGNTRIKAAVFEGSSVLEYFVFEKNELEKRIEKILEKFPNCSDLVVASVGDVEKQSFLSFEKQLNVHFFTHEDI
FPFHNKYATPKTLGIDRMILAAGATLQFPKQNRLVIDAGTCITYDFIDENDNYLGGAISPGLRLRYETLHNYTARLPLLT
LDQPHSYIGDSTAQAIHSGVVNGFVYEIDGFIDEYRSNFSNFIIILTGGDAEFLAKRLKNTIFANSNFLLESLSQTYQYK
IDND
>Mature_244_residues
MILTVDVGNTRIKAAVFEGSSVLEYFVFEKNELEKRIEKILEKFPNCSDLVVASVGDVEKQSFLSFEKQLNVHFFTHEDI
FPFHNKYATPKTLGIDRMILAAGATLQFPKQNRLVIDAGTCITYDFIDENDNYLGGAISPGLRLRYETLHNYTARLPLLT
LDQPHSYIGDSTAQAIHSGVVNGFVYEIDGFIDEYRSNFSNFIIILTGGDAEFLAKRLKNTIFANSNFLLESLSQTYQYK
IDND

Specific function: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis

COG id: COG1521

COG function: function code K; Putative transcriptional regulator, homolog of Bvg accessory factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type III pantothenate kinase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAX_FLAJ1 (A5FK26)

Other databases:

- EMBL:   CP000685
- RefSeq:   YP_001193762.1
- ProteinModelPortal:   A5FK26
- SMR:   A5FK26
- STRING:   A5FK26
- GeneID:   5094168
- GenomeReviews:   CP000685_GR
- KEGG:   fjo:Fjoh_1411
- eggNOG:   COG1521
- HOGENOM:   HBG634537
- OMA:   YPELLVF
- ProtClustDB:   PRK13320
- BioCyc:   FJOH376686:FJOH_1411-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01274
- InterPro:   IPR004619
- TIGRFAMs:   TIGR00671

Pfam domain/function: PF03309 Bvg_acc_factor

EC number: =2.7.1.33

Molecular weight: Translated: 27636; Mature: 27636

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: NA

Important sites: ACT_SITE 96-96 BINDING 87-87 BINDING 120-120 BINDING 172-172

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILTVDVGNTRIKAAVFEGSSVLEYFVFEKNELEKRIEKILEKFPNCSDLVVASVGDVEK
CEEEEECCCCEEEEEEECCCCEEHHHHCCHHHHHHHHHHHHHHCCCCCCEEEECCCCHHH
QSFLSFEKQLNVHFFTHEDIFPFHNKYATPKTLGIDRMILAAGATLQFPKQNRLVIDAGT
HHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCCCHHEECCCCEEECCCCCCEEEECCC
CITYDFIDENDNYLGGAISPGLRLRYETLHNYTARLPLLTLDQPHSYIGDSTAQAIHSGV
EEEEEEECCCCCEECCCCCCCCEEEHHHHHCHHHCCCEEEECCCCHHCCCHHHHHHHHHH
VNGFVYEIDGFIDEYRSNFSNFIIILTGGDAEFLAKRLKNTIFANSNFLLESLSQTYQYK
HHCEEEEHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHEECCCHHHHHHHHHHEEEE
IDND
ECCC
>Mature Secondary Structure
MILTVDVGNTRIKAAVFEGSSVLEYFVFEKNELEKRIEKILEKFPNCSDLVVASVGDVEK
CEEEEECCCCEEEEEEECCCCEEHHHHCCHHHHHHHHHHHHHHCCCCCCEEEECCCCHHH
QSFLSFEKQLNVHFFTHEDIFPFHNKYATPKTLGIDRMILAAGATLQFPKQNRLVIDAGT
HHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCCCHHEECCCCEEECCCCCCEEEECCC
CITYDFIDENDNYLGGAISPGLRLRYETLHNYTARLPLLTLDQPHSYIGDSTAQAIHSGV
EEEEEEECCCCCEECCCCCCCCEEEHHHHHCHHHCCCEEEECCCCHHCCCHHHHHHHHHH
VNGFVYEIDGFIDEYRSNFSNFIIILTGGDAEFLAKRLKNTIFANSNFLLESLSQTYQYK
HHCEEEEHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHEECCCHHHHHHHHHHEEEE
IDND
ECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA