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The map label for this gene is tolC [H]

Identifier: 146299026

GI number: 146299026

Start: 1442616

End: 1443950

Strand: Direct

Name: tolC [H]

Synonym: Fjoh_1266

Alternate gene names: 146299026

Gene position: 1442616-1443950 (Clockwise)

Preceding gene: 146299025

Following gene: 146299027

Centisome position: 23.66

GC content: 34.68

Gene sequence:

>1335_bases
ATGAAAAGAATCTTTCTTATAGTTTTGTGTACAATAGGCTTGTCTGCCGCCGCACAAACCACTACTTTAACTCTGAAAGA
CGCCGTTAACTACGCGCTTCAAAATAAAGCCGATGCAAAAAAGGCAAAACTTCAGGTTGAAAACAGCGAATATAAAATTC
AGGAAGTACGTTCAAGAGCATTGCCTCAAATTTCTGCAAACGGAAATTTAACGTATAACCCAATTATTCAGACTACGGTT
ATTGATGGAGCAGCATTTGGTGCGCCGGGAACTGCAATTCAGGCAGCATTTGGACAAAAATGGACATCAACTGCAGGGGT
TTCTTTAACTCAGGCAATTTTTGACCAATCAGTTTTTACAGGATTAAGAGCTGCAAAATCTACTCGTGAGTTTTATCAAA
TAAACGATCAGTTAACAGAAGAACAAGTTATTGAAAGAGTTGCAAATAACTACTATTCAGTTTACGTACAAAAAGAAAGA
TTAACTTTATTAGACAGCAATTACGTAAATACTACAAAAGTTCGTGACATCGTACAAGGACAGTTTGATAACGGTTTAGC
AAAAAAAATTGACTTAGATCGTATCATTGTAAAAATGTCGAACATCGATACAGAGCGTCAGCAGATTAAAAACCAAATTA
CTTTACAGGAAAACGCATTGAAGTTTTACATGGGTATGCCTATTGAAACTCAAATCGATATGCCAAAAGAAGAATTTGAA
GTTGTTCCGGCTGCCTTAACTCAAGAGCCAAATATTGAAAACAGAACAGAATATCTGCTTTTGAAAAAACAAGAAGAGCT
TTTGGTTCTTAACAAAAAAGCTGTTCAGGCAGGATATTATCCAACACTTTCTCTAACTGCAGGTTATAATTATATTGGTC
AGGGACCTGAATTTCCTTGGTTTGCAAAACCAGAAAAAGGGGTTTACTGGTCAGATTTCTCTGCAATTGGATTAAACTTA
CACGTACCAATTTTTACAGGTTTTGGAACTCGTGCAAAAGTAAGACAAGCTGATGTTGAAATCAGATCTCTTCAGGAAGA
CATCAAAGACACAAAACTTTCTCTTGATTTAGATTATAGAAATGCCATGGCTCAAATCGAGAATAACTTGGTAACTATTG
AAAATCAGAAAGAAAATATGCGTTTAGCAACTGAAATTTTAAGTAATACTAAAAACAATTATCTTCAGGGTTTAGCATCT
TTAACCGATTTGCTTGACGCAGAAAATGCATCACTTGAAGCTCAAAATAATTATACAAGAGCAGTTTTAAATTATAAAAT
TGCCGAAATATCTCTAATCAAATCAAAAGGCGAACTTAAATCTCTTACTAAATAA

Upstream 100 bases:

>100_bases
ATTAAAAATTAACCATTCCAAAAATTGATCGTCATTTTTCTGTGAGGGTAAAGAAAAAATGACGGTCCCATCTCAAATTT
AAAAATAAATAGTAACACTT

Downstream 100 bases:

>100_bases
CAAATTACAATGAAGAAAATAATTATAACAATCGTGATCATAGCCGTAGCTTTTTTCGGGATAAGCTATATCTTAAATAA
AAATAAAGCAGAAAACGAAG

Product: outer membrane efflux protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 444; Mature: 444

Protein sequence:

>444_residues
MKRIFLIVLCTIGLSAAAQTTTLTLKDAVNYALQNKADAKKAKLQVENSEYKIQEVRSRALPQISANGNLTYNPIIQTTV
IDGAAFGAPGTAIQAAFGQKWTSTAGVSLTQAIFDQSVFTGLRAAKSTREFYQINDQLTEEQVIERVANNYYSVYVQKER
LTLLDSNYVNTTKVRDIVQGQFDNGLAKKIDLDRIIVKMSNIDTERQQIKNQITLQENALKFYMGMPIETQIDMPKEEFE
VVPAALTQEPNIENRTEYLLLKKQEELLVLNKKAVQAGYYPTLSLTAGYNYIGQGPEFPWFAKPEKGVYWSDFSAIGLNL
HVPIFTGFGTRAKVRQADVEIRSLQEDIKDTKLSLDLDYRNAMAQIENNLVTIENQKENMRLATEILSNTKNNYLQGLAS
LTDLLDAENASLEAQNNYTRAVLNYKIAEISLIKSKGELKSLTK

Sequences:

>Translated_444_residues
MKRIFLIVLCTIGLSAAAQTTTLTLKDAVNYALQNKADAKKAKLQVENSEYKIQEVRSRALPQISANGNLTYNPIIQTTV
IDGAAFGAPGTAIQAAFGQKWTSTAGVSLTQAIFDQSVFTGLRAAKSTREFYQINDQLTEEQVIERVANNYYSVYVQKER
LTLLDSNYVNTTKVRDIVQGQFDNGLAKKIDLDRIIVKMSNIDTERQQIKNQITLQENALKFYMGMPIETQIDMPKEEFE
VVPAALTQEPNIENRTEYLLLKKQEELLVLNKKAVQAGYYPTLSLTAGYNYIGQGPEFPWFAKPEKGVYWSDFSAIGLNL
HVPIFTGFGTRAKVRQADVEIRSLQEDIKDTKLSLDLDYRNAMAQIENNLVTIENQKENMRLATEILSNTKNNYLQGLAS
LTDLLDAENASLEAQNNYTRAVLNYKIAEISLIKSKGELKSLTK
>Mature_444_residues
MKRIFLIVLCTIGLSAAAQTTTLTLKDAVNYALQNKADAKKAKLQVENSEYKIQEVRSRALPQISANGNLTYNPIIQTTV
IDGAAFGAPGTAIQAAFGQKWTSTAGVSLTQAIFDQSVFTGLRAAKSTREFYQINDQLTEEQVIERVANNYYSVYVQKER
LTLLDSNYVNTTKVRDIVQGQFDNGLAKKIDLDRIIVKMSNIDTERQQIKNQITLQENALKFYMGMPIETQIDMPKEEFE
VVPAALTQEPNIENRTEYLLLKKQEELLVLNKKAVQAGYYPTLSLTAGYNYIGQGPEFPWFAKPEKGVYWSDFSAIGLNL
HVPIFTGFGTRAKVRQADVEIRSLQEDIKDTKLSLDLDYRNAMAQIENNLVTIENQKENMRLATEILSNTKNNYLQGLAS
LTDLLDAENASLEAQNNYTRAVLNYKIAEISLIKSKGELKSLTK

Specific function: May be specialized for signal sequence independent, extracellular secretion in Gram-negative bacteria [H]

COG id: COG1538

COG function: function code MU; Outer membrane protein

Gene ontology:

Cell location: Cell outer membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

None

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 240 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423
- InterPro:   IPR010130 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 49871; Mature: 49871

Theoretical pI: Translated: 6.20; Mature: 6.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRIFLIVLCTIGLSAAAQTTTLTLKDAVNYALQNKADAKKAKLQVENSEYKIQEVRSRA
CCEEEEEEEEHHCCCCCCCEEEEEHHHHHHHHHHCCCCCCHHEEEECCCCHHHHHHHHHC
LPQISANGNLTYNPIIQTTVIDGAAFGAPGTAIQAAFGQKWTSTAGVSLTQAIFDQSVFT
CCEEECCCCEEECCEEEEEEECCCCCCCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHH
GLRAAKSTREFYQINDQLTEEQVIERVANNYYSVYVQKERLTLLDSNYVNTTKVRDIVQG
HHHHHHHHHHHHHHHHHCCHHHHHHHHHCCEEEEEEEECEEEEEECCCCCHHHHHHHHHC
QFDNGLAKKIDLDRIIVKMSNIDTERQQIKNQITLQENALKFYMGMPIETQIDMPKEEFE
CCCCCCHHHCCHHHHEEEHHCCCHHHHHHHHHEEEHHCCEEEEECCCCCCCCCCCHHHHH
VVPAALTQEPNIENRTEYLLLKKQEELLVLNKKAVQAGYYPTLSLTAGYNYIGQGPEFPW
HHHHHHCCCCCCCCCCEEEEEECCCCEEEEEHHHHHCCCCCEEEEECCCCCCCCCCCCCC
FAKPEKGVYWSDFSAIGLNLHVPIFTGFGTRAKVRQADVEIRSLQEDIKDTKLSLDLDYR
CCCCCCCEEECCCCEEEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCEEEEEEHHH
NAMAQIENNLVTIENQKENMRLATEILSNTKNNYLQGLASLTDLLDAENASLEAQNNYTR
HHHHHHHCCEEEEECCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCEECCCCCEE
AVLNYKIAEISLIKSKGELKSLTK
EEEEEEEEEEEEECCCCCHHHCCC
>Mature Secondary Structure
MKRIFLIVLCTIGLSAAAQTTTLTLKDAVNYALQNKADAKKAKLQVENSEYKIQEVRSRA
CCEEEEEEEEHHCCCCCCCEEEEEHHHHHHHHHHCCCCCCHHEEEECCCCHHHHHHHHHC
LPQISANGNLTYNPIIQTTVIDGAAFGAPGTAIQAAFGQKWTSTAGVSLTQAIFDQSVFT
CCEEECCCCEEECCEEEEEEECCCCCCCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHH
GLRAAKSTREFYQINDQLTEEQVIERVANNYYSVYVQKERLTLLDSNYVNTTKVRDIVQG
HHHHHHHHHHHHHHHHHCCHHHHHHHHHCCEEEEEEEECEEEEEECCCCCHHHHHHHHHC
QFDNGLAKKIDLDRIIVKMSNIDTERQQIKNQITLQENALKFYMGMPIETQIDMPKEEFE
CCCCCCHHHCCHHHHEEEHHCCCHHHHHHHHHEEEHHCCEEEEECCCCCCCCCCCHHHHH
VVPAALTQEPNIENRTEYLLLKKQEELLVLNKKAVQAGYYPTLSLTAGYNYIGQGPEFPW
HHHHHHCCCCCCCCCCEEEEEECCCCEEEEEHHHHHCCCCCEEEEECCCCCCCCCCCCCC
FAKPEKGVYWSDFSAIGLNLHVPIFTGFGTRAKVRQADVEIRSLQEDIKDTKLSLDLDYR
CCCCCCCEEECCCCEEEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCEEEEEEHHH
NAMAQIENNLVTIENQKENMRLATEILSNTKNNYLQGLASLTDLLDAENASLEAQNNYTR
HHHHHHHCCEEEEECCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCEECCCCCEE
AVLNYKIAEISLIKSKGELKSLTK
EEEEEEEEEEEEECCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]