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The map label for this gene is atpB2 [H]

Identifier: 146298816

GI number: 146298816

Start: 1199003

End: 1200178

Strand: Direct

Name: atpB2 [H]

Synonym: Fjoh_1055

Alternate gene names: 146298816

Gene position: 1199003-1200178 (Clockwise)

Preceding gene: 146298815

Following gene: 146298817

Centisome position: 19.67

GC content: 33.5

Gene sequence:

>1176_bases
ATGGTGATTTCAAACAAACCACTCAGATTAATTCTTGCAGCTTTTGTAGCTTCTCTGCCTATTATGAGTTTCGCAAACTC
AGAGATTGACTCAACGCATGTACAAAATGAAAGTGCTCATGAAGAGAAAGTAATTTCACATGAAACACATGGTGAAGACG
AACACGCAGCTAAAGATCCAAAAGCAAAAGTGGATGCTTTTATTGATCACCACTTACAGGATTCTCATGACTTTGTTTTC
TTTTCAGATGAAAAAGAAAATAAACACTATGGGTTTTCGTTACCAGTTATACTTATAGATGGAGGATTGAAAATTTTCTC
ATCTTCAAAATTACACCACGGAGAAGAAGTGGCAGAAGTTGATGGAAACTATTATAAATTAGTTCACGGTAAAATTTACA
AAACAGATGCAGCCGGAACAATCAACTTTGACGAACATGGTCATCCTTCAAACGTAAAACCATTAGATTTTTCGATTACA
AAAAATGTTGTATCAATGCTTTTTGTTTCAGTATTATTATTCTTAATGTTTACTGGTTTAGCAAGATCATATAAAAAAGG
ACCAATCCCAACTGGATTTGGAAGAGTTTTAGAACCGCTTATTATTTTTATCAGAGACGAAATTGCAGTTCCTAATATTG
GAGAGAAAAAATACCGTAAATATATGGGTTACCTTTTAACTGTATTTTTCTTTGTTTGGTTGTTAAACTTATTAGGAATG
ACTCCTCTTGGAATTAACGTTACAGGTAATATTGCTATCACAGTTTGTTTAGCAGCATTTACATTTATCATTACTCAATT
TAGTGCAAACAAAGATTATTGGGGACACATCTTCTGGATGCCAGGAGTGCCAGTTCCAATGAAAATCATTTTAGCTCCAA
TTGAGGTTTTAGGAACACTAACAAAACCATTTGCATTATTAATTCGTTTGTATGCAAACATTACTGCAGGTCACGTAGTA
ATTATGAGTTTGATTGCTATGATTTTCGTAGGTAAAAATTTAGCAGCAGATTTGCCAATCTCATTAGGATTAACATTGTT
TATCTCTGTTATTGAAGTTTTAGTTGCATTTTTACAGGCTTTCATCTTCACGATGTTATCATCATTATTTATTGGTATGG
CTGTTCAGGATCATGATCACGCTCACCACCATGAAGACGAAACAGCAATTATTTAA

Upstream 100 bases:

>100_bases
GAAGGTTCAAAAATAATTTTTCATATCCTTTTGAATATTAATAAAAAATGTACCTTTGCACCAAATTTTAGAAACGTAAA
AAAATAAGATTTTCCACGAT

Downstream 100 bases:

>100_bases
TTTAGAAGTTTAATTTTATATATATAAATACTTATGGGAACAATTCCAACTTTAGTAGGTGCAGGTTTAGTAGTAATCGG
TGCAGGTTTAGGTTTAGGTA

Product: ATP synthase F0 subunit A

Products: ADP; phosphate; H+

Alternate protein names: ATP synthase F0 sector subunit a 2; F-ATPase subunit 6 2 [H]

Number of amino acids: Translated: 391; Mature: 391

Protein sequence:

>391_residues
MVISNKPLRLILAAFVASLPIMSFANSEIDSTHVQNESAHEEKVISHETHGEDEHAAKDPKAKVDAFIDHHLQDSHDFVF
FSDEKENKHYGFSLPVILIDGGLKIFSSSKLHHGEEVAEVDGNYYKLVHGKIYKTDAAGTINFDEHGHPSNVKPLDFSIT
KNVVSMLFVSVLLFLMFTGLARSYKKGPIPTGFGRVLEPLIIFIRDEIAVPNIGEKKYRKYMGYLLTVFFFVWLLNLLGM
TPLGINVTGNIAITVCLAAFTFIITQFSANKDYWGHIFWMPGVPVPMKIILAPIEVLGTLTKPFALLIRLYANITAGHVV
IMSLIAMIFVGKNLAADLPISLGLTLFISVIEVLVAFLQAFIFTMLSSLFIGMAVQDHDHAHHHEDETAII

Sequences:

>Translated_391_residues
MVISNKPLRLILAAFVASLPIMSFANSEIDSTHVQNESAHEEKVISHETHGEDEHAAKDPKAKVDAFIDHHLQDSHDFVF
FSDEKENKHYGFSLPVILIDGGLKIFSSSKLHHGEEVAEVDGNYYKLVHGKIYKTDAAGTINFDEHGHPSNVKPLDFSIT
KNVVSMLFVSVLLFLMFTGLARSYKKGPIPTGFGRVLEPLIIFIRDEIAVPNIGEKKYRKYMGYLLTVFFFVWLLNLLGM
TPLGINVTGNIAITVCLAAFTFIITQFSANKDYWGHIFWMPGVPVPMKIILAPIEVLGTLTKPFALLIRLYANITAGHVV
IMSLIAMIFVGKNLAADLPISLGLTLFISVIEVLVAFLQAFIFTMLSSLFIGMAVQDHDHAHHHEDETAII
>Mature_391_residues
MVISNKPLRLILAAFVASLPIMSFANSEIDSTHVQNESAHEEKVISHETHGEDEHAAKDPKAKVDAFIDHHLQDSHDFVF
FSDEKENKHYGFSLPVILIDGGLKIFSSSKLHHGEEVAEVDGNYYKLVHGKIYKTDAAGTINFDEHGHPSNVKPLDFSIT
KNVVSMLFVSVLLFLMFTGLARSYKKGPIPTGFGRVLEPLIIFIRDEIAVPNIGEKKYRKYMGYLLTVFFFVWLLNLLGM
TPLGINVTGNIAITVCLAAFTFIITQFSANKDYWGHIFWMPGVPVPMKIILAPIEVLGTLTKPFALLIRLYANITAGHVV
IMSLIAMIFVGKNLAADLPISLGLTLFISVIEVLVAFLQAFIFTMLSSLFIGMAVQDHDHAHHHEDETAII

Specific function: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane [H]

COG id: COG0356

COG function: function code C; F0F1-type ATP synthase, subunit a

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase A chain family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000568
- InterPro:   IPR023011 [H]

Pfam domain/function: PF00119 ATP-synt_A [H]

EC number: 3.6.3.14

Molecular weight: Translated: 43500; Mature: 43500

Theoretical pI: Translated: 6.55; Mature: 6.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVISNKPLRLILAAFVASLPIMSFANSEIDSTHVQNESAHEEKVISHETHGEDEHAAKDP
CCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCHHHHHHHHCCCCCCCHHHCCCC
KAKVDAFIDHHLQDSHDFVFFSDEKENKHYGFSLPVILIDGGLKIFSSSKLHHGEEVAEV
HHHHHHHHHHHCCCCCCEEEEECCCCCCCCCEEEEEEEEECCEEEECCCCCCCCCHHHHC
DGNYYKLVHGKIYKTDAAGTINFDEHGHPSNVKPLDFSITKNVVSMLFVSVLLFLMFTGL
CCCEEEEEECEEEEECCCCEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
ARSYKKGPIPTGFGRVLEPLIIFIRDEIAVPNIGEKKYRKYMGYLLTVFFFVWLLNLLGM
HHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
TPLGINVTGNIAITVCLAAFTFIITQFSANKDYWGHIFWMPGVPVPMKIILAPIEVLGTL
CCCCEEEECHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHH
TKPFALLIRLYANITAGHVVIMSLIAMIFVGKNLAADLPISLGLTLFISVIEVLVAFLQA
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
FIFTMLSSLFIGMAVQDHDHAHHHEDETAII
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MVISNKPLRLILAAFVASLPIMSFANSEIDSTHVQNESAHEEKVISHETHGEDEHAAKDP
CCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCHHHHHHHHCCCCCCCHHHCCCC
KAKVDAFIDHHLQDSHDFVFFSDEKENKHYGFSLPVILIDGGLKIFSSSKLHHGEEVAEV
HHHHHHHHHHHCCCCCCEEEEECCCCCCCCCEEEEEEEEECCEEEECCCCCCCCCHHHHC
DGNYYKLVHGKIYKTDAAGTINFDEHGHPSNVKPLDFSITKNVVSMLFVSVLLFLMFTGL
CCCEEEEEECEEEEECCCCEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
ARSYKKGPIPTGFGRVLEPLIIFIRDEIAVPNIGEKKYRKYMGYLLTVFFFVWLLNLLGM
HHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
TPLGINVTGNIAITVCLAAFTFIITQFSANKDYWGHIFWMPGVPVPMKIILAPIEVLGTL
CCCCEEEECHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHH
TKPFALLIRLYANITAGHVVIMSLIAMIFVGKNLAADLPISLGLTLFISVIEVLVAFLQA
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
FIFTMLSSLFIGMAVQDHDHAHHHEDETAII
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Borate; diphosphate; HCO3- [C]

Metal ions: Co2+; Fe2+; Mn2+; Zn2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: Ca2+; CN-; Efrapeptin; Ethidiumbromide; Guanidines analogs; Oligomycin; Quercetin; Trialkyl tin derivatives; Venturicidin [C]

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12093901 [H]