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The map label for this gene is pilC [H]

Identifier: 146298377

GI number: 146298377

Start: 676280

End: 677407

Strand: Direct

Name: pilC [H]

Synonym: Fjoh_0614

Alternate gene names: 146298377

Gene position: 676280-677407 (Clockwise)

Preceding gene: 146298376

Following gene: 146298378

Centisome position: 11.09

GC content: 32.45

Gene sequence:

>1128_bases
ATGAGTCTAGATTTAAGTACATATAAAGCCCCAAAAGCCGAAAAGACAGATTTTAAATTACCATCTGGCTCGGCATCTTT
TCAGTTATCGAAAAAATTATCTGATAAGAAAAAAGAGGTGTTTTACAGAGAACTGGGGATGCTTTTAAAATCAGGAGTAG
ATTTTAAAAAAGCATTGGAAATTCTCAGCAATCAGTCTGCCCATAAATTGGAAAAAGAAATCATACTGGAAATAAAAGAA
AAGGTGATTTCGGGAAGAAGTATTTATGAGTCAATGAAAGAAACCAATCAGTTTTCGGCATACGAATATTACAGTATTCA
GATTGGAGAAGAAACCAGAAAACTGGAAGAAGTTTTAGGAGAACTTCAAAAATATTTCAACAGAAAAATTCAGATGAAAA
GGCAGATCGTTTCTGTTTTAACCTATCCTGCAATCGTAATGATTGTAACGGTTTTGGTGCTATATTTTATGCTGAATAAA
GTTGTCCCAATGTTTAGCTCTGTATTCAAACAATTTGGCAGCGAACTTCCAAAAAGCACACAAGTAATTATCAAAATTTC
CAATCATTCTGGAACTATTTTTTCAATCGTTTTTGCTGTCATTATTGGATTAGTCATTATGCATACAATGCTGAAAGAAA
AAGAATTTTATCGTGCTCTTACATCAAAAATTGTTTTAAGAATTCCCTATTTCGGAAACCTCATCAGAAAAATTTATATC
TCACGTTTTTGTCAGGCCATGAATTTATTAACGACCTCAAAAACGACTTTAATAAACTCATTATCCTTAACAGCAAAAAT
GATTGGCTTTTATCCTATCGAAAAAGCCATAGAGGAAATTAAAGAGGATATTACAAGAGGTGCCTCATTACATGAAAGTT
TAAAAAAGCATTCAGTGTTTGAAAACAAAATGGTATCAATGGTTGAAGTAGCAGAACAGGTAAACCAGCTGGAAACCATG
TTTGAAAGACTTACGGAACAATATAACGAAGAAATAAGCCATCAGACAAAAATGATTGGCGTTATTCTGGAACCTATGAT
TATCATTGTCATTGGCGTAATTGTAGGAGTAATTATGGTGTCGATGTATGCACCAATGTTCGATTTAAGTAAAATTATAA
ATAAATAG

Upstream 100 bases:

>100_bases
AAAAACTAAAATTAAATGTAGAGATCAATGAAAACGAATCTTCTTTAAGTTTCTATAAAAGAGTTTATGCTAATGAATTA
CTGCAAAAGATACCCAAATA

Downstream 100 bases:

>100_bases
TAATAGTTTCATTACAATTTGTATTTTTGCGACCCATCGAATTAACATAATTTAATAAATAAATGCATACAAATGTCGAA
AACGATTAAAACATTATTAA

Product: type II secretion system protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 375; Mature: 374

Protein sequence:

>375_residues
MSLDLSTYKAPKAEKTDFKLPSGSASFQLSKKLSDKKKEVFYRELGMLLKSGVDFKKALEILSNQSAHKLEKEIILEIKE
KVISGRSIYESMKETNQFSAYEYYSIQIGEETRKLEEVLGELQKYFNRKIQMKRQIVSVLTYPAIVMIVTVLVLYFMLNK
VVPMFSSVFKQFGSELPKSTQVIIKISNHSGTIFSIVFAVIIGLVIMHTMLKEKEFYRALTSKIVLRIPYFGNLIRKIYI
SRFCQAMNLLTTSKTTLINSLSLTAKMIGFYPIEKAIEEIKEDITRGASLHESLKKHSVFENKMVSMVEVAEQVNQLETM
FERLTEQYNEEISHQTKMIGVILEPMIIIVIGVIVGVIMVSMYAPMFDLSKIINK

Sequences:

>Translated_375_residues
MSLDLSTYKAPKAEKTDFKLPSGSASFQLSKKLSDKKKEVFYRELGMLLKSGVDFKKALEILSNQSAHKLEKEIILEIKE
KVISGRSIYESMKETNQFSAYEYYSIQIGEETRKLEEVLGELQKYFNRKIQMKRQIVSVLTYPAIVMIVTVLVLYFMLNK
VVPMFSSVFKQFGSELPKSTQVIIKISNHSGTIFSIVFAVIIGLVIMHTMLKEKEFYRALTSKIVLRIPYFGNLIRKIYI
SRFCQAMNLLTTSKTTLINSLSLTAKMIGFYPIEKAIEEIKEDITRGASLHESLKKHSVFENKMVSMVEVAEQVNQLETM
FERLTEQYNEEISHQTKMIGVILEPMIIIVIGVIVGVIMVSMYAPMFDLSKIINK
>Mature_374_residues
SLDLSTYKAPKAEKTDFKLPSGSASFQLSKKLSDKKKEVFYRELGMLLKSGVDFKKALEILSNQSAHKLEKEIILEIKEK
VISGRSIYESMKETNQFSAYEYYSIQIGEETRKLEEVLGELQKYFNRKIQMKRQIVSVLTYPAIVMIVTVLVLYFMLNKV
VPMFSSVFKQFGSELPKSTQVIIKISNHSGTIFSIVFAVIIGLVIMHTMLKEKEFYRALTSKIVLRIPYFGNLIRKIYIS
RFCQAMNLLTTSKTTLINSLSLTAKMIGFYPIEKAIEEIKEDITRGASLHESLKKHSVFENKMVSMVEVAEQVNQLETMF
ERLTEQYNEEISHQTKMIGVILEPMIIIVIGVIVGVIMVSMYAPMFDLSKIINK

Specific function: Involved in the translocation of the type IV pilin (pilA) [H]

COG id: COG1459

COG function: function code NU; Type II secretory pathway, component PulF

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP F family [H]

Homologues:

Organism=Escherichia coli, GI1789724, Length=350, Percent_Identity=24, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1786295, Length=345, Percent_Identity=25.5072463768116, Blast_Score=122, Evalue=3e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003004
- InterPro:   IPR018076
- InterPro:   IPR001992 [H]

Pfam domain/function: PF00482 GSPII_F [H]

EC number: NA

Molecular weight: Translated: 42979; Mature: 42847

Theoretical pI: Translated: 9.83; Mature: 9.83

Prosite motif: PS00874 T2SP_F

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLDLSTYKAPKAEKTDFKLPSGSASFQLSKKLSDKKKEVFYRELGMLLKSGVDFKKALE
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
ILSNQSAHKLEKEIILEIKEKVISGRSIYESMKETNQFSAYEYYSIQIGEETRKLEEVLG
HHCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCEEEEEEEECHHHHHHHHHHH
ELQKYFNRKIQMKRQIVSVLTYPAIVMIVTVLVLYFMLNKVVPMFSSVFKQFGSELPKST
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
QVIIKISNHSGTIFSIVFAVIIGLVIMHTMLKEKEFYRALTSKIVLRIPYFGNLIRKIYI
EEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
SRFCQAMNLLTTSKTTLINSLSLTAKMIGFYPIEKAIEEIKEDITRGASLHESLKKHSVF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
ENKMVSMVEVAEQVNQLETMFERLTEQYNEEISHQTKMIGVILEPMIIIVIGVIVGVIMV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SMYAPMFDLSKIINK
HHHCCHHHHHHHHCC
>Mature Secondary Structure 
SLDLSTYKAPKAEKTDFKLPSGSASFQLSKKLSDKKKEVFYRELGMLLKSGVDFKKALE
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
ILSNQSAHKLEKEIILEIKEKVISGRSIYESMKETNQFSAYEYYSIQIGEETRKLEEVLG
HHCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCEEEEEEEECHHHHHHHHHHH
ELQKYFNRKIQMKRQIVSVLTYPAIVMIVTVLVLYFMLNKVVPMFSSVFKQFGSELPKST
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
QVIIKISNHSGTIFSIVFAVIIGLVIMHTMLKEKEFYRALTSKIVLRIPYFGNLIRKIYI
EEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
SRFCQAMNLLTTSKTTLINSLSLTAKMIGFYPIEKAIEEIKEDITRGASLHESLKKHSVF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
ENKMVSMVEVAEQVNQLETMFERLTEQYNEEISHQTKMIGVILEPMIIIVIGVIVGVIMV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SMYAPMFDLSKIINK
HHHCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1971619; 10984043 [H]