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The map label for this gene is mauR [H]

Identifier: 146284420

GI number: 146284420

Start: 4462129

End: 4463076

Strand: Direct

Name: mauR [H]

Synonym: PST_4109

Alternate gene names: 146284420

Gene position: 4462129-4463076 (Clockwise)

Preceding gene: 146284419

Following gene: 146284433

Centisome position: 97.69

GC content: 62.24

Gene sequence:

>948_bases
ATGCAGATCGACGAAGAGCTGACCCTGAAGAAGCTGGAAGTGTTTCTGGCCTTCATGCGCAGCGGCAATCTGGGCAAGGC
CGCGGTCGAGCTGAACACCAGCAACGTCAGCGTGCATCGCGCCATCCACTCGCTTGAAAGCGCGTTGCGATGCCCGCTGT
TCAAGCACGAGGGGCGCAACCTGATTCCGCTGGAAAGTGCCTATGTACTCGAAGAGCGTGCCCAGCAGCTGGTCAAGGAC
GTGCTCGAGACGGTGCGGCGTACCCGCGAAGCGGCCGGTTTCTCGGCCGAGCGCTTCAAGCTCGGTGCGCTCTACTCGCT
GACGGTGAAGACCGTGCCGCAGCTGATCATGGGCCTGAAGCTGCGCCGCAGCGAGCTCAACATCGACCTGATCCTGGGCT
CCAACGTCGACCTGCTCTACAAGCTGAAGAACATGGAGCTGGACGCCATTCTGGTGTCACTCAACGAGAGCGTCGCCGAC
CCGGACTGTGCCCAGGTGCAGCTGTTTTCCGACGACATTTTCCTCGCCGCGCCAGCCGACTCGCCGTTCGCCAACCAGAG
CGAAGTGGATCTCAGCGATCTGCGTGACGCCACTTTCATCACCCTGTCCCAAGGCTTCGCCACCCATCAGGACGGCAACC
GGGTGTTCCAGCTAGCGGGTTTCGAGCCGAAGGTGGCGATGCAGGTGAACGACATCTTCACGCTGCTCAGCATGGTCAAT
TCCGGGGTCGGTTACGCGCTGCTGCCGGGGCGGGTGGGCATGGTCTACGAATCGCGGGTGCGATTGATACCGCTGCAGGC
GCGCTATCACCTGCAGCAGCACATCGGCGTGGTGTTTCTAAAGGCCAAGGAGCGCGACCCGAACCTGCTGGCGCTGCTCG
CCGAATGCCGGATGTATGCCCGGCGCGCGCTGGAGCAGAACGAGGATGCCAAGCCTGAAACGACGTAG

Upstream 100 bases:

>100_bases
AAGAACTCGCCCTGCCCTGATCGCCTGCACTGCTCCGCTTTCGCGCCCCGCCTGAGTACGAGTTCGGCATAATCGTCTGC
CCGACCGCGGAGCAACGGCC

Downstream 100 bases:

>100_bases
GGTGGAAAACCCGCGCAGCGGTTTTCCACGTGTTGGCATATGGCCAGCCGGATCGGCATGATCGGCGCCGCAGTGGTGGA
AGAGGCTTCGCCGTCTTCCA

Product: malonate utilization transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 315; Mature: 315

Protein sequence:

>315_residues
MQIDEELTLKKLEVFLAFMRSGNLGKAAVELNTSNVSVHRAIHSLESALRCPLFKHEGRNLIPLESAYVLEERAQQLVKD
VLETVRRTREAAGFSAERFKLGALYSLTVKTVPQLIMGLKLRRSELNIDLILGSNVDLLYKLKNMELDAILVSLNESVAD
PDCAQVQLFSDDIFLAAPADSPFANQSEVDLSDLRDATFITLSQGFATHQDGNRVFQLAGFEPKVAMQVNDIFTLLSMVN
SGVGYALLPGRVGMVYESRVRLIPLQARYHLQQHIGVVFLKAKERDPNLLALLAECRMYARRALEQNEDAKPETT

Sequences:

>Translated_315_residues
MQIDEELTLKKLEVFLAFMRSGNLGKAAVELNTSNVSVHRAIHSLESALRCPLFKHEGRNLIPLESAYVLEERAQQLVKD
VLETVRRTREAAGFSAERFKLGALYSLTVKTVPQLIMGLKLRRSELNIDLILGSNVDLLYKLKNMELDAILVSLNESVAD
PDCAQVQLFSDDIFLAAPADSPFANQSEVDLSDLRDATFITLSQGFATHQDGNRVFQLAGFEPKVAMQVNDIFTLLSMVN
SGVGYALLPGRVGMVYESRVRLIPLQARYHLQQHIGVVFLKAKERDPNLLALLAECRMYARRALEQNEDAKPETT
>Mature_315_residues
MQIDEELTLKKLEVFLAFMRSGNLGKAAVELNTSNVSVHRAIHSLESALRCPLFKHEGRNLIPLESAYVLEERAQQLVKD
VLETVRRTREAAGFSAERFKLGALYSLTVKTVPQLIMGLKLRRSELNIDLILGSNVDLLYKLKNMELDAILVSLNESVAD
PDCAQVQLFSDDIFLAAPADSPFANQSEVDLSDLRDATFITLSQGFATHQDGNRVFQLAGFEPKVAMQVNDIFTLLSMVN
SGVGYALLPGRVGMVYESRVRLIPLQARYHLQQHIGVVFLKAKERDPNLLALLAECRMYARRALEQNEDAKPETT

Specific function: Transcriptional regulator of the mau genes for malonate utilization [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI2367136, Length=290, Percent_Identity=24.8275862068966, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI157672245, Length=248, Percent_Identity=22.5806451612903, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1788887, Length=246, Percent_Identity=21.5447154471545, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1788481, Length=253, Percent_Identity=25.6916996047431, Blast_Score=61, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 35202; Mature: 35202

Theoretical pI: Translated: 5.99; Mature: 5.99

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQIDEELTLKKLEVFLAFMRSGNLGKAAVELNTSNVSVHRAIHSLESALRCPLFKHEGRN
CCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHCCCCHHCCCCC
LIPLESAYVLEERAQQLVKDVLETVRRTREAAGFSAERFKLGALYSLTVKTVPQLIMGLK
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHEEECHHEEHHHHHHHHHHHCCH
LRRSELNIDLILGSNVDLLYKLKNMELDAILVSLNESVADPDCAQVQLFSDDIFLAAPAD
HHHCCCCEEEEECCCCEEEEEECCCCEEEEEEECCCCCCCCCCCEEEEECCCEEEECCCC
SPFANQSEVDLSDLRDATFITLSQGFATHQDGNRVFQLAGFEPKVAMQVNDIFTLLSMVN
CCCCCCCCCCHHHCCCCEEEEEECCCCCCCCCCEEEEEECCCCCEEEHHHHHHHHHHHHH
SGVGYALLPGRVGMVYESRVRLIPLQARYHLQQHIGVVFLKAKERDPNLLALLAECRMYA
CCCCEEECCCCCCEEEECCEEEEEHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHH
RRALEQNEDAKPETT
HHHHHCCCCCCCCCC
>Mature Secondary Structure
MQIDEELTLKKLEVFLAFMRSGNLGKAAVELNTSNVSVHRAIHSLESALRCPLFKHEGRN
CCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHCCCCHHCCCCC
LIPLESAYVLEERAQQLVKDVLETVRRTREAAGFSAERFKLGALYSLTVKTVPQLIMGLK
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHEEECHHEEHHHHHHHHHHHCCH
LRRSELNIDLILGSNVDLLYKLKNMELDAILVSLNESVADPDCAQVQLFSDDIFLAAPAD
HHHCCCCEEEEECCCCEEEEEECCCCEEEEEEECCCCCCCCCCCEEEEECCCEEEECCCC
SPFANQSEVDLSDLRDATFITLSQGFATHQDGNRVFQLAGFEPKVAMQVNDIFTLLSMVN
CCCCCCCCCCHHHCCCCEEEEEECCCCCCCCCCEEEEEECCCCCEEEHHHHHHHHHHHHH
SGVGYALLPGRVGMVYESRVRLIPLQARYHLQQHIGVVFLKAKERDPNLLALLAECRMYA
CCCCEEECCCCCCEEEECCEEEEEHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHH
RRALEQNEDAKPETT
HHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA