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The map label for this gene is metX

Identifier: 146284282

GI number: 146284282

Start: 4307453

End: 4308592

Strand: Direct

Name: metX

Synonym: PST_3970

Alternate gene names: 146284282

Gene position: 4307453-4308592 (Clockwise)

Preceding gene: 146284281

Following gene: 146284283

Centisome position: 94.31

GC content: 64.21

Gene sequence:

>1140_bases
ATGCCCACTGCAATTCCCGCCGATTCCGTTGGCCTGGTGAGTCCGCAGGTCGCGCATTTTGCCGAACCACTGACACTCGC
CTGCGGCCGCACGCTGGCCGATTACCAGCTGATCTACGAAACCTACGGCGAACTCAACGCCGCGCGCAGCAATGCCGTGC
TGATCTGCCATGCCCTGTCCGGCCATCACCATGCTGCCGGCTACCACAGCGAGGACGATCGCAAGCCCGGCTGGTGGGAT
TCCTGCATCGGCCCGGGCAAGGCCATCGATACCGATCGTTTCTTTGTCGTCAGCCTGAACAACCTCGGCGGCTGCAACGG
CTCCACCGGCCCCAGCAGCACCAACCCGGCCACCGGCAAACCCTACGGCGCGGACTTCCCGGTCGTCACCGTGGAGGACT
GGGTGCACAGCCAGGCACGCCTGGCTGATCGGCTCGGCATCAACCAGTGGGCCGCAGTGGTCGGCGGCAGCCTGGGCGGC
ATGCAGGCCCTGCAGTGGGCCATCAGCTATCCCGAGCGGGTGCGTCACTGCCTGGCGATTGCCTCGGCGCCCAAGCTGTC
GGCGCAGAACATCGCCTTCAACGAAGTGGCACGCCAGGCGATCCTCTCCGATCCCGAGTTCCACGGCGGGCATTTCCAAG
AAATGGGGGTCATCCCCAAGCGCGGCCTGATGCTGGCACGCATGGTCGGCCACATCACCTACCTGTCCGATGATGCCATG
GGCACCAAGTTCGGCCGCGGGTTGAAGAGCGAAAAGCTCAACTACGACTTCAACAGCGTCGAGTTCCAGGTCGAGAGCTA
CCTGCGCTACCAGGGCGAGGAATTCTCCGGGCGCTTCGACGCCAACACCTATCTGCTGATGACCAAGGCGCTGGATTACT
TCGACCCGGCCGCGGCCAACGATGACGACCTGGCCCGGACTTTCGAGGTCGCTCAGGCGGACTTCTGCGTGATGTCCTTC
ACCACCGACTGGCGCTTCTCGCCGGAACGCTCGCGGGAAATCGTCGACGCCCTGCTCGCGGCGCGCAAGAACGTCTGCTA
CCTGGAGATCGACGCGCCGCAGGGTCACGACGCCTTCCTGATTCCCAACCCCCGCTACCTGCAAGCCTTCCGCGGTTACA
TGAACCGCATAGCCGTATAA

Upstream 100 bases:

>100_bases
GCGAAATGGCAACGCGCCCGCCCGCCGCTGTATTTCAGGATGAATTGCAGCGCGCTTACCTTTAGACTTTGCCGCCTTCT
CCAAGCAAGAGCCAGGGTCG

Downstream 100 bases:

>100_bases
GGAACGAAGATGCGCGCCGATCTGGACATCATCCAAGACTGGATCCCGGCCGGCAGCCGAGTCCTCGACCTCGGCTGCGG
CAACGGCGAGCTGCTCGCCT

Product: homoserine O-acetyltransferase

Products: NA

Alternate protein names: Homoserine O-trans-acetylase; HTA; Homoserine transacetylase

Number of amino acids: Translated: 379; Mature: 378

Protein sequence:

>379_residues
MPTAIPADSVGLVSPQVAHFAEPLTLACGRTLADYQLIYETYGELNAARSNAVLICHALSGHHHAAGYHSEDDRKPGWWD
SCIGPGKAIDTDRFFVVSLNNLGGCNGSTGPSSTNPATGKPYGADFPVVTVEDWVHSQARLADRLGINQWAAVVGGSLGG
MQALQWAISYPERVRHCLAIASAPKLSAQNIAFNEVARQAILSDPEFHGGHFQEMGVIPKRGLMLARMVGHITYLSDDAM
GTKFGRGLKSEKLNYDFNSVEFQVESYLRYQGEEFSGRFDANTYLLMTKALDYFDPAAANDDDLARTFEVAQADFCVMSF
TTDWRFSPERSREIVDALLAARKNVCYLEIDAPQGHDAFLIPNPRYLQAFRGYMNRIAV

Sequences:

>Translated_379_residues
MPTAIPADSVGLVSPQVAHFAEPLTLACGRTLADYQLIYETYGELNAARSNAVLICHALSGHHHAAGYHSEDDRKPGWWD
SCIGPGKAIDTDRFFVVSLNNLGGCNGSTGPSSTNPATGKPYGADFPVVTVEDWVHSQARLADRLGINQWAAVVGGSLGG
MQALQWAISYPERVRHCLAIASAPKLSAQNIAFNEVARQAILSDPEFHGGHFQEMGVIPKRGLMLARMVGHITYLSDDAM
GTKFGRGLKSEKLNYDFNSVEFQVESYLRYQGEEFSGRFDANTYLLMTKALDYFDPAAANDDDLARTFEVAQADFCVMSF
TTDWRFSPERSREIVDALLAARKNVCYLEIDAPQGHDAFLIPNPRYLQAFRGYMNRIAV
>Mature_378_residues
PTAIPADSVGLVSPQVAHFAEPLTLACGRTLADYQLIYETYGELNAARSNAVLICHALSGHHHAAGYHSEDDRKPGWWDS
CIGPGKAIDTDRFFVVSLNNLGGCNGSTGPSSTNPATGKPYGADFPVVTVEDWVHSQARLADRLGINQWAAVVGGSLGGM
QALQWAISYPERVRHCLAIASAPKLSAQNIAFNEVARQAILSDPEFHGGHFQEMGVIPKRGLMLARMVGHITYLSDDAMG
TKFGRGLKSEKLNYDFNSVEFQVESYLRYQGEEFSGRFDANTYLLMTKALDYFDPAAANDDDLARTFEVAQADFCVMSFT
TDWRFSPERSREIVDALLAARKNVCYLEIDAPQGHDAFLIPNPRYLQAFRGYMNRIAV

Specific function: Unknown

COG id: COG2021

COG function: function code E; Homoserine acetyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. HTA family

Homologues:

Organism=Saccharomyces cerevisiae, GI6324052, Length=224, Percent_Identity=37.0535714285714, Blast_Score=149, Evalue=7e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): METX_PSEU5 (A4VRJ2)

Other databases:

- EMBL:   CP000304
- RefSeq:   YP_001174435.1
- STRING:   A4VRJ2
- GeneID:   5096931
- GenomeReviews:   CP000304_GR
- KEGG:   psa:PST_3970
- eggNOG:   COG2021
- HOGENOM:   HBG692920
- OMA:   VSFTSDW
- PhylomeDB:   A4VRJ2
- ProtClustDB:   PRK00175
- BioCyc:   PSTU379731:PST_3970-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00296
- InterPro:   IPR000073
- InterPro:   IPR008220
- PIRSF:   PIRSF000443
- TIGRFAMs:   TIGR01392

Pfam domain/function: PF00561 Abhydrolase_1

EC number: =2.3.1.31

Molecular weight: Translated: 41698; Mature: 41567

Theoretical pI: Translated: 5.74; Mature: 5.74

Prosite motif: NA

Important sites: ACT_SITE 157-157 ACT_SITE 356-356

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTAIPADSVGLVSPQVAHFAEPLTLACGRTLADYQLIYETYGELNAARSNAVLICHALS
CCCCCCCCCCCCCCCHHHHHHCCHHHHHCCHHHHHHHHHHHHHHHHCCCCCEEEEEEECC
GHHHAAGYHSEDDRKPGWWDSCIGPGKAIDTDRFFVVSLNNLGGCNGSTGPSSTNPATGK
CCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCC
PYGADFPVVTVEDWVHSQARLADRLGINQWAAVVGGSLGGMQALQWAISYPERVRHCLAI
CCCCCCCEEEHHHHHHHHHHHHHHHCHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHH
ASAPKLSAQNIAFNEVARQAILSDPEFHGGHFQEMGVIPKRGLMLARMVGHITYLSDDAM
HCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHCCCCCCHHHHHHHHHHHHHEECCCCC
GTKFGRGLKSEKLNYDFNSVEFQVESYLRYQGEEFSGRFDANTYLLMTKALDYFDPAAAN
CHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEECCCEEEEEEHHHHHCCCCCCC
DDDLARTFEVAQADFCVMSFTTDWRFSPERSREIVDALLAARKNVCYLEIDAPQGHDAFL
CHHHHHHHHHHHHCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCEEEEEEECCCCCCEEE
IPNPRYLQAFRGYMNRIAV
CCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PTAIPADSVGLVSPQVAHFAEPLTLACGRTLADYQLIYETYGELNAARSNAVLICHALS
CCCCCCCCCCCCCCHHHHHHCCHHHHHCCHHHHHHHHHHHHHHHHCCCCCEEEEEEECC
GHHHAAGYHSEDDRKPGWWDSCIGPGKAIDTDRFFVVSLNNLGGCNGSTGPSSTNPATGK
CCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCC
PYGADFPVVTVEDWVHSQARLADRLGINQWAAVVGGSLGGMQALQWAISYPERVRHCLAI
CCCCCCCEEEHHHHHHHHHHHHHHHCHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHH
ASAPKLSAQNIAFNEVARQAILSDPEFHGGHFQEMGVIPKRGLMLARMVGHITYLSDDAM
HCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHCCCCCCHHHHHHHHHHHHHEECCCCC
GTKFGRGLKSEKLNYDFNSVEFQVESYLRYQGEEFSGRFDANTYLLMTKALDYFDPAAAN
CHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEECCCEEEEEEHHHHHCCCCCCC
DDDLARTFEVAQADFCVMSFTTDWRFSPERSREIVDALLAARKNVCYLEIDAPQGHDAFL
CHHHHHHHHHHHHCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCEEEEEEECCCCCCEEE
IPNPRYLQAFRGYMNRIAV
CCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA