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The map label for this gene is yggS [C]

Identifier: 146284278

GI number: 146284278

Start: 4302961

End: 4303650

Strand: Direct

Name: yggS [C]

Synonym: PST_3966

Alternate gene names: 146284278

Gene position: 4302961-4303650 (Clockwise)

Preceding gene: 146284275

Following gene: 146284279

Centisome position: 94.21

GC content: 65.51

Gene sequence:

>690_bases
ATGTCCACGATAGAGAAGAATATTGCAAAGGTCGGAGCACGCATCCGTGAGGCGGCGCAAGCTGTGGGTCGTGAGCCCGC
CACGGTGGGCCTGCTGGCCGTCAGCAAGACCCAGCCAGCCGCTGCCATTCGCGACGCATTCGCCGCCGGCCTGCGCGATT
TCGGCGAGAACTATCTGCAGGAGGCGCTGGACAAGCAGGCCGAGCTGGACGACCTGCCGCTGACCTGGCATTTCATCGGC
CCCATCCAGTCGAACAAGACCAAGGCCATCGCAGAACACTTCGACTGGGTGCACTCGGTGGATCGCCTGAAGATCGCCCA
GCGCCTCTCCGATCAGCGCCCTGAGGCGCTGCCGCCGTTGAACATCTGCCTGCAGGTGAATGTCAGTGGCGAGGCCAGCA
AGTCCGGCTGTGCACCGCAGGAGGTGCAGCAGCTGGCGCGGGCGATCACCGCGCTGCCGCGACTGCGCCTGCGCGGTCTG
ATGTGCATCCCGGCCCCCAGCGAGGATCCGGCCGAGCAACGCGCCGCCTTCGCCCGTCTGCGGCAGCTGCGCGACGAGCT
GGCACTTGATCTGGATACGCTGTCCATGGGCATGAGTCAGGATCTGGAAGCTGCCATTGCCGAAGGTGCGACCTGGGTTC
GCATCGGCACTGCTCTCTTCGGCGCCCGTGACTACGGCCGCCCTCAATAA

Upstream 100 bases:

>100_bases
TGGCGCTGAAGGCCAGCAGTTCAGTGATATCCATGGGACTCCCCAATTACAAGCGAGCAGGTAGAATGCCGCGCAGACCC
CAAGGCGGCGGGCGCAAGTA

Downstream 100 bases:

>100_bases
AGGAATCGCTATGACCTCTCCCCGCATCGCCTTCATCGGCGCCGGCAACATGGCCGCCAGCCTGATCGGCGGGCTGCGTG
CCCAGGGCATCGCCGCTGAT

Product: TIM-barrel fold family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 229; Mature: 228

Protein sequence:

>229_residues
MSTIEKNIAKVGARIREAAQAVGREPATVGLLAVSKTQPAAAIRDAFAAGLRDFGENYLQEALDKQAELDDLPLTWHFIG
PIQSNKTKAIAEHFDWVHSVDRLKIAQRLSDQRPEALPPLNICLQVNVSGEASKSGCAPQEVQQLARAITALPRLRLRGL
MCIPAPSEDPAEQRAAFARLRQLRDELALDLDTLSMGMSQDLEAAIAEGATWVRIGTALFGARDYGRPQ

Sequences:

>Translated_229_residues
MSTIEKNIAKVGARIREAAQAVGREPATVGLLAVSKTQPAAAIRDAFAAGLRDFGENYLQEALDKQAELDDLPLTWHFIG
PIQSNKTKAIAEHFDWVHSVDRLKIAQRLSDQRPEALPPLNICLQVNVSGEASKSGCAPQEVQQLARAITALPRLRLRGL
MCIPAPSEDPAEQRAAFARLRQLRDELALDLDTLSMGMSQDLEAAIAEGATWVRIGTALFGARDYGRPQ
>Mature_228_residues
STIEKNIAKVGARIREAAQAVGREPATVGLLAVSKTQPAAAIRDAFAAGLRDFGENYLQEALDKQAELDDLPLTWHFIGP
IQSNKTKAIAEHFDWVHSVDRLKIAQRLSDQRPEALPPLNICLQVNVSGEASKSGCAPQEVQQLARAITALPRLRLRGLM
CIPAPSEDPAEQRAAFARLRQLRDELALDLDTLSMGMSQDLEAAIAEGATWVRIGTALFGARDYGRPQ

Specific function: Perhaps involved in proline biosynthesis [H]

COG id: COG0325

COG function: function code R; Predicted enzyme with a TIM-barrel fold

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0001 family [H]

Homologues:

Organism=Homo sapiens, GI6005842, Length=230, Percent_Identity=38.695652173913, Blast_Score=130, Evalue=1e-30,
Organism=Escherichia coli, GI1789321, Length=236, Percent_Identity=54.2372881355932, Blast_Score=249, Evalue=9e-68,
Organism=Caenorhabditis elegans, GI17533025, Length=234, Percent_Identity=35.8974358974359, Blast_Score=111, Evalue=3e-25,
Organism=Saccharomyces cerevisiae, GI6319435, Length=229, Percent_Identity=36.6812227074236, Blast_Score=121, Evalue=9e-29,
Organism=Drosophila melanogaster, GI45550861, Length=211, Percent_Identity=38.8625592417062, Blast_Score=125, Evalue=2e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001608
- InterPro:   IPR011078 [H]

Pfam domain/function: PF01168 Ala_racemase_N [H]

EC number: NA

Molecular weight: Translated: 24958; Mature: 24827

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: PS01211 UPF0001

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTIEKNIAKVGARIREAAQAVGREPATVGLLAVSKTQPAAAIRDAFAAGLRDFGENYLQ
CCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHH
EALDKQAELDDLPLTWHFIGPIQSNKTKAIAEHFDWVHSVDRLKIAQRLSDQRPEALPPL
HHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
NICLQVNVSGEASKSGCAPQEVQQLARAITALPRLRLRGLMCIPAPSEDPAEQRAAFARL
EEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHH
RQLRDELALDLDTLSMGMSQDLEAAIAEGATWVRIGTALFGARDYGRPQ
HHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
STIEKNIAKVGARIREAAQAVGREPATVGLLAVSKTQPAAAIRDAFAAGLRDFGENYLQ
CHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHH
EALDKQAELDDLPLTWHFIGPIQSNKTKAIAEHFDWVHSVDRLKIAQRLSDQRPEALPPL
HHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
NICLQVNVSGEASKSGCAPQEVQQLARAITALPRLRLRGLMCIPAPSEDPAEQRAAFARL
EEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHH
RQLRDELALDLDTLSMGMSQDLEAAIAEGATWVRIGTALFGARDYGRPQ
HHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1676385; 10984043; 2107123 [H]