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The map label for this gene is pyrR [H]

Identifier: 146284270

GI number: 146284270

Start: 4295163

End: 4295678

Strand: Direct

Name: pyrR [H]

Synonym: PST_3958

Alternate gene names: 146284270

Gene position: 4295163-4295678 (Clockwise)

Preceding gene: 146284269

Following gene: 146284271

Centisome position: 94.04

GC content: 66.47

Gene sequence:

>516_bases
ATGATCCTGCCAAATCCCGAACAGCTGCTGCCCGAGATGACCGAGGCACTGGAGCGCTACCTGAACGAGCGCGACATCCG
CGAGCCGCGCTTCATCGGCATTCGTACAGGCGGAGTCTGGGTCGCCCAGGCGCTGCTCGAAGCACGCGGACAGAGCGAAC
CGCTCGGCGTGCTCGACGTGTCCTTCTATCGCGACGACTTCACCCAGAAGGGCTTGCATCCGCAGGTGCAGCCTTCGGAG
CTGCCATTCGAGATCGAGGGCCAGCACCTGGTGCTGATCGACGACGTACTGATGACCGGCCGTACCATCCGCGCCGCGCT
CAACGAGCTGTTCGACTACGGCCGGCCTGCCAGCGTGACCCTCGTCTGCCTGCTCGACCTCAACGCCCGCGAACTGCCGA
TCCGGCCTGACGTGGTCGGGGCGACGCTGTCGCTGGCGCCGGATCAGCGCATCAAGCTGCTTGGTCCGGCGCCGCTGGCG
CTCGAGCCGCAGCGACTGGAAGCCAGCCAGTCCTGA

Upstream 100 bases:

>100_bases
GAGGCTATCGCGAACGGCCGGTCGATGCCCTGGCCGCCGCCCTGTTACTGGAAGGCTGGCTGAACGATCACGCCGGCGCC
TGATCCCGAAAGGAGACCCC

Downstream 100 bases:

>100_bases
CGCCGGCACCCTCCATCTAACGCCCATCTCCCGCTGCCCACCGAGATCCTGCGATGACGCCCACTGACGCCAAGCGCCCG
CTACAGCTGAACGACCAAGG

Product: bifunctional pyrimidine regulatory protein PyrR uracil phosphoribosyltransferase

Products: NA

Alternate protein names: Pyrimidine operon regulatory protein; Uracil phosphoribosyltransferase; UPRTase [H]

Number of amino acids: Translated: 171; Mature: 171

Protein sequence:

>171_residues
MILPNPEQLLPEMTEALERYLNERDIREPRFIGIRTGGVWVAQALLEARGQSEPLGVLDVSFYRDDFTQKGLHPQVQPSE
LPFEIEGQHLVLIDDVLMTGRTIRAALNELFDYGRPASVTLVCLLDLNARELPIRPDVVGATLSLAPDQRIKLLGPAPLA
LEPQRLEASQS

Sequences:

>Translated_171_residues
MILPNPEQLLPEMTEALERYLNERDIREPRFIGIRTGGVWVAQALLEARGQSEPLGVLDVSFYRDDFTQKGLHPQVQPSE
LPFEIEGQHLVLIDDVLMTGRTIRAALNELFDYGRPASVTLVCLLDLNARELPIRPDVVGATLSLAPDQRIKLLGPAPLA
LEPQRLEASQS
>Mature_171_residues
MILPNPEQLLPEMTEALERYLNERDIREPRFIGIRTGGVWVAQALLEARGQSEPLGVLDVSFYRDDFTQKGLHPQVQPSE
LPFEIEGQHLVLIDDVLMTGRTIRAALNELFDYGRPASVTLVCLLDLNARELPIRPDVVGATLSLAPDQRIKLLGPAPLA
LEPQRLEASQS

Specific function: Displays also a weak uracil phosphoribosyltransferase activity which is not physiologically significant [H]

COG id: COG2065

COG function: function code F; Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000836
- InterPro:   IPR023050 [H]

Pfam domain/function: PF00156 Pribosyltran [H]

EC number: =2.4.2.9 [H]

Molecular weight: Translated: 19072; Mature: 19072

Theoretical pI: Translated: 4.44; Mature: 4.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILPNPEQLLPEMTEALERYLNERDIREPRFIGIRTGGVWVAQALLEARGQSEPLGVLDV
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHCCCCCCCEEEEH
SFYRDDFTQKGLHPQVQPSELPFEIEGQHLVLIDDVLMTGRTIRAALNELFDYGRPASVT
HHHHHHHHHCCCCCCCCCCCCCEEECCCEEEEEHHHHHCCHHHHHHHHHHHHCCCCCCEE
LVCLLDLNARELPIRPDVVGATLSLAPDQRIKLLGPAPLALEPQRLEASQS
EEEEEECCCCCCCCCCCCCCCEEEECCCCCEEEECCCCCCCCHHHHCCCCC
>Mature Secondary Structure
MILPNPEQLLPEMTEALERYLNERDIREPRFIGIRTGGVWVAQALLEARGQSEPLGVLDV
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHCCCCCCCEEEEH
SFYRDDFTQKGLHPQVQPSELPFEIEGQHLVLIDDVLMTGRTIRAALNELFDYGRPASVT
HHHHHHHHHCCCCCCCCCCCCCEEECCCEEEEEHHHHHCCHHHHHHHHHHHHCCCCCCEE
LVCLLDLNARELPIRPDVVGATLSLAPDQRIKLLGPAPLALEPQRLEASQS
EEEEEECCCCCCCCCCCCCCCEEEECCCCCEEEECCCCCCCCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA