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The map label for this gene is sldA [H]

Identifier: 146284053

GI number: 146284053

Start: 4042677

End: 4044719

Strand: Direct

Name: sldA [H]

Synonym: PST_3741

Alternate gene names: 146284053

Gene position: 4042677-4044719 (Clockwise)

Preceding gene: 146284052

Following gene: 146284056

Centisome position: 88.51

GC content: 65.79

Gene sequence:

>2043_bases
ATGCGCCTCTGGATCGCGCTCGCCGCGCTGACATTAAGCCTGCCCGACATTCACCACGCCCAGGCTCAGAACAGCCCGAC
CACCGAACGGGCGACAGCGGCCTCCCCCGCGCCTTCGGACTGGACGTCGTACGGCCGCGACAACGCAGCCACCCGCTATT
CGCCGCTCAGGCAAATCACGCGCGACAATGTCGACCAGCTCGAGCCCGCCTGGGTGTACCAGACCGGCGACATGCCGCCA
CCGGAAGTGGACGACAAGTGGGCCCCGGAAAACACCCCGCTGAAAGTCGGCAACTCGCTGTACCTGTGCAGCGCCATGAA
TATCCTGATCGGGCTCGATGCCGGAAGTGGTCGCGAACGCTGGCGCTTCGATCCACAGGTGCCGATCGATCACATCCCCT
ATTCAGCAGCCTGTCGGGGCGTCAGCTATTACGAGGTGCCCGATCCAGAGCCGGCCCAGGCCTGCGCGCGGCGCGTCATC
GAGGGCACGCTCGATGCGCGGCTGATCGCCGTCGATGCAGACACCGGCCAGCCGTGCGAGGACTTCGGCAACTCCGGGCA
GGTCAATCTGCTCGAAGGGATGGGCGATTCGCCCCCCGGCTACGTCGCGGTGACCTCGGCACCGACCATCGTGCGTAACG
TGGTCGTGGTCGGCCACCAGGTGCTCGACGGGCAAAAGGAGGATGCGCCATCCGGGGTGATCCGCGGCTACGATGCCGAA
ACCGGCGAGCTCGCCTGGGCATGGGACATGGGGCGTCCGGGCGAGACGGGCATGCCGGCCGAGGGCGAGCAGTACACGCG
CGGCACGCCCAATGCCTGGACGACCTTTTCGGCCGACGACGAGCTCGGCCTGGTCTACGTGCCCATGGGCAATTCGGCTG
TGGATTACTTCAGCGGCAACAGAGAAGACTACGAGCACCCCTACTCCACCGCCCTGGTCGCGCTCGACATCACCAGCGGC
GAAGTCGCCTGGGTTTTCCAGACGGTGCACAACGATGTCTGGGACTATGACCTGGGCTCGCAGGGCACGCTTGCCGACTT
TCCCATGGGAGAGGGCCAGAGCGTCCCGGCTGTCATTCTGCCGACCAAACAGGGCGATATCTTCGTGCTTGACCGGCGCA
CCGGCGAGCCGCTCACCGAGGTGCAGGAGCGCCCGGTGCCGGCCAGCAAGCTGCCCGACGAACAGCTGTCGCCGACTCAG
CCCTTCTCGGTCGGCATGCCGACACTCGCCAAGCCCAAGCTCACCGAACGCGACGCCTGGGGCTTTTCACCCCTGGATCA
GCTCTGGTGCCGGATTCAATTCCTGCAGTCCGACTACGAGGGGATGTACACCCCGCCGAGCGTCGAGCGGCCCTTCATCC
AATACCCCGGCTACAACGGCGGCAACGACTGGGGCGGTGGTTCGCTGGACCCCGAGCGCGGCATCTTTGTCGCCAACTAC
ACCGACTTGCCGATGCGTGATCAGCTCATCCGTCGCGAAGAGGCTGATGAGAAAGGCATGGTGCCGCTGGGCGAGCCGGG
TGGGACGACCGATTCCGGCGGGCCGGTGCCCCAGGCAGGCTCTCCTTACGCCATCTCGATCAAGCCATGGCGCAACGGCC
TGACCGGTATCCCCTGCACCCGGCCACCCTACGGCGGAATCATGGCCATCGACCTGGCCACCCGTGAGGTACTGTGGGAC
AAGCCACTGGGCACCGCCCGCAACAATGGCCCCTTCGGCATCCCCTCGCGCCTGCCCTTCACCATCGGCACGCCCAACAA
TGGCGGCTCGGTGATCACCGCCGGTGGGCTGATCTTTATTGCCGCCACTACGGACGACCTCATTCGCGCCATCGATATCG
ATACCGGCGAAGTGGTCTGGCAGGACGTGCTGCCCGCTGGCGGCCAGGCGACGCCGATGACCTACGAGGTCAACGGACGC
CAGTACCTGGCCATCTTTGCCGGCGGTCACCATTTCATGGAGACCAAGATCGGCGATTACCTGGTGGTCTACAGCCTGCC
CACCCCGGGGGACTCCAGCTCCACCGAAACGCTGGAGGAGTGA

Upstream 100 bases:

>100_bases
CTGGCCCCTGGTACCCCGTCTGGTCGCGCCCGCGGTCATCGCGCTGCTTACATTGCTGTTCATCCCCACGGTTCGCCGCC
ACTCGAATTGAGGTAGACCT

Downstream 100 bases:

>100_bases
CTAGCGAAATGGCGGCTCGTCGAAGCTGCGCAGCTTGCGCGAGTGCAGCGAGTTCAGCTGGCTGCGCAACAGGTCGAGGG
CGGCGATGCCGATCTTCAGG

Product: glucose dehydrogenase

Products: NA

Alternate protein names: D-arabitol dehydrogenase large subunit; ARDH; D-sorbitol dehydrogenase subunit sldA; SLDH; Gluconate/polyol dehydrogenase large subunit [H]

Number of amino acids: Translated: 680; Mature: 680

Protein sequence:

>680_residues
MRLWIALAALTLSLPDIHHAQAQNSPTTERATAASPAPSDWTSYGRDNAATRYSPLRQITRDNVDQLEPAWVYQTGDMPP
PEVDDKWAPENTPLKVGNSLYLCSAMNILIGLDAGSGRERWRFDPQVPIDHIPYSAACRGVSYYEVPDPEPAQACARRVI
EGTLDARLIAVDADTGQPCEDFGNSGQVNLLEGMGDSPPGYVAVTSAPTIVRNVVVVGHQVLDGQKEDAPSGVIRGYDAE
TGELAWAWDMGRPGETGMPAEGEQYTRGTPNAWTTFSADDELGLVYVPMGNSAVDYFSGNREDYEHPYSTALVALDITSG
EVAWVFQTVHNDVWDYDLGSQGTLADFPMGEGQSVPAVILPTKQGDIFVLDRRTGEPLTEVQERPVPASKLPDEQLSPTQ
PFSVGMPTLAKPKLTERDAWGFSPLDQLWCRIQFLQSDYEGMYTPPSVERPFIQYPGYNGGNDWGGGSLDPERGIFVANY
TDLPMRDQLIRREEADEKGMVPLGEPGGTTDSGGPVPQAGSPYAISIKPWRNGLTGIPCTRPPYGGIMAIDLATREVLWD
KPLGTARNNGPFGIPSRLPFTIGTPNNGGSVITAGGLIFIAATTDDLIRAIDIDTGEVVWQDVLPAGGQATPMTYEVNGR
QYLAIFAGGHHFMETKIGDYLVVYSLPTPGDSSSTETLEE

Sequences:

>Translated_680_residues
MRLWIALAALTLSLPDIHHAQAQNSPTTERATAASPAPSDWTSYGRDNAATRYSPLRQITRDNVDQLEPAWVYQTGDMPP
PEVDDKWAPENTPLKVGNSLYLCSAMNILIGLDAGSGRERWRFDPQVPIDHIPYSAACRGVSYYEVPDPEPAQACARRVI
EGTLDARLIAVDADTGQPCEDFGNSGQVNLLEGMGDSPPGYVAVTSAPTIVRNVVVVGHQVLDGQKEDAPSGVIRGYDAE
TGELAWAWDMGRPGETGMPAEGEQYTRGTPNAWTTFSADDELGLVYVPMGNSAVDYFSGNREDYEHPYSTALVALDITSG
EVAWVFQTVHNDVWDYDLGSQGTLADFPMGEGQSVPAVILPTKQGDIFVLDRRTGEPLTEVQERPVPASKLPDEQLSPTQ
PFSVGMPTLAKPKLTERDAWGFSPLDQLWCRIQFLQSDYEGMYTPPSVERPFIQYPGYNGGNDWGGGSLDPERGIFVANY
TDLPMRDQLIRREEADEKGMVPLGEPGGTTDSGGPVPQAGSPYAISIKPWRNGLTGIPCTRPPYGGIMAIDLATREVLWD
KPLGTARNNGPFGIPSRLPFTIGTPNNGGSVITAGGLIFIAATTDDLIRAIDIDTGEVVWQDVLPAGGQATPMTYEVNGR
QYLAIFAGGHHFMETKIGDYLVVYSLPTPGDSSSTETLEE
>Mature_680_residues
MRLWIALAALTLSLPDIHHAQAQNSPTTERATAASPAPSDWTSYGRDNAATRYSPLRQITRDNVDQLEPAWVYQTGDMPP
PEVDDKWAPENTPLKVGNSLYLCSAMNILIGLDAGSGRERWRFDPQVPIDHIPYSAACRGVSYYEVPDPEPAQACARRVI
EGTLDARLIAVDADTGQPCEDFGNSGQVNLLEGMGDSPPGYVAVTSAPTIVRNVVVVGHQVLDGQKEDAPSGVIRGYDAE
TGELAWAWDMGRPGETGMPAEGEQYTRGTPNAWTTFSADDELGLVYVPMGNSAVDYFSGNREDYEHPYSTALVALDITSG
EVAWVFQTVHNDVWDYDLGSQGTLADFPMGEGQSVPAVILPTKQGDIFVLDRRTGEPLTEVQERPVPASKLPDEQLSPTQ
PFSVGMPTLAKPKLTERDAWGFSPLDQLWCRIQFLQSDYEGMYTPPSVERPFIQYPGYNGGNDWGGGSLDPERGIFVANY
TDLPMRDQLIRREEADEKGMVPLGEPGGTTDSGGPVPQAGSPYAISIKPWRNGLTGIPCTRPPYGGIMAIDLATREVLWD
KPLGTARNNGPFGIPSRLPFTIGTPNNGGSVITAGGLIFIAATTDDLIRAIDIDTGEVVWQDVLPAGGQATPMTYEVNGR
QYLAIFAGGHHFMETKIGDYLVVYSLPTPGDSSSTETLEE

Specific function: Catalyzes the oxidation of glycerol to glycerone. Also acts, more slowly, on a number of other polyols including D- sorbitol, D-arabinitol, D-mannitol, meso-erythritol, adonitol and propylene glycol [H]

COG id: COG4993

COG function: function code G; Glucose dehydrogenase

Gene ontology:

Cell location: Secreted (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial PQQ dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1786316, Length=645, Percent_Identity=44.031007751938, Blast_Score=514, Evalue=1e-147,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019556
- InterPro:   IPR019551
- InterPro:   IPR018391
- InterPro:   IPR002372
- InterPro:   IPR011047 [H]

Pfam domain/function: PF01011 PQQ; PF10535 PQQ_C; PF10527 PQQ_N [H]

EC number: =1.1.99.22 [H]

Molecular weight: Translated: 73701; Mature: 73701

Theoretical pI: Translated: 4.16; Mature: 4.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLWIALAALTLSLPDIHHAQAQNSPTTERATAASPAPSDWTSYGRDNAATRYSPLRQIT
CEEEEEEEEHHHCCCCCHHHHCCCCCCCHHHCCCCCCCCHHHHCCCCCCHHHHHHHHHHH
RDNVDQLEPAWVYQTGDMPPPEVDDKWAPENTPLKVGNSLYLCSAMNILIGLDAGSGRER
HCCHHHCCCEEEEECCCCCCCCCCCCCCCCCCCEEECCCEEEEEECEEEEEECCCCCCCC
WRFDPQVPIDHIPYSAACRGVSYYEVPDPEPAQACARRVIEGTLDARLIAVDADTGQPCE
CEECCCCCCCCCCHHHHHCCCEEEECCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCHH
DFGNSGQVNLLEGMGDSPPGYVAVTSAPTIVRNVVVVGHQVLDGQKEDAPSGVIRGYDAE
HHCCCCCEEEECCCCCCCCCEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCC
TGELAWAWDMGRPGETGMPAEGEQYTRGTPNAWTTFSADDELGLVYVPMGNSAVDYFSGN
CCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCEEEEECCCCEEHHCCCC
REDYEHPYSTALVALDITSGEVAWVFQTVHNDVWDYDLGSQGTLADFPMGEGQSVPAVIL
CCCCCCCCCEEEEEEEECCCCEEEEEEHHHCCCCCCCCCCCCCEECCCCCCCCCCCEEEE
PTKQGDIFVLDRRTGEPLTEVQERPVPASKLPDEQLSPTQPFSVGMPTLAKPKLTERDAW
ECCCCCEEEEECCCCCCHHHHHHCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
GFSPLDQLWCRIQFLQSDYEGMYTPPSVERPFIQYPGYNGGNDWGGGSLDPERGIFVANY
CCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCEEEEEC
TDLPMRDQLIRREEADEKGMVPLGEPGGTTDSGGPVPQAGSPYAISIKPWRNGLTGIPCT
CCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCC
RPPYGGIMAIDLATREVLWDKPLGTARNNGPFGIPSRLPFTIGTPNNGGSVITAGGLIFI
CCCCCCEEEEEEHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCEEEECCEEEE
AATTDDLIRAIDIDTGEVVWQDVLPAGGQATPMTYEVNGRQYLAIFAGGHHFMETKIGDY
EECHHHHEEEEECCCCHHHHHHHCCCCCCCCCEEEEECCCEEEEEEECCCEEEEECCCCE
LVVYSLPTPGDSSSTETLEE
EEEEECCCCCCCCCCHHHCC
>Mature Secondary Structure
MRLWIALAALTLSLPDIHHAQAQNSPTTERATAASPAPSDWTSYGRDNAATRYSPLRQIT
CEEEEEEEEHHHCCCCCHHHHCCCCCCCHHHCCCCCCCCHHHHCCCCCCHHHHHHHHHHH
RDNVDQLEPAWVYQTGDMPPPEVDDKWAPENTPLKVGNSLYLCSAMNILIGLDAGSGRER
HCCHHHCCCEEEEECCCCCCCCCCCCCCCCCCCEEECCCEEEEEECEEEEEECCCCCCCC
WRFDPQVPIDHIPYSAACRGVSYYEVPDPEPAQACARRVIEGTLDARLIAVDADTGQPCE
CEECCCCCCCCCCHHHHHCCCEEEECCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCHH
DFGNSGQVNLLEGMGDSPPGYVAVTSAPTIVRNVVVVGHQVLDGQKEDAPSGVIRGYDAE
HHCCCCCEEEECCCCCCCCCEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCC
TGELAWAWDMGRPGETGMPAEGEQYTRGTPNAWTTFSADDELGLVYVPMGNSAVDYFSGN
CCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCEEEEECCCCEEHHCCCC
REDYEHPYSTALVALDITSGEVAWVFQTVHNDVWDYDLGSQGTLADFPMGEGQSVPAVIL
CCCCCCCCCEEEEEEEECCCCEEEEEEHHHCCCCCCCCCCCCCEECCCCCCCCCCCEEEE
PTKQGDIFVLDRRTGEPLTEVQERPVPASKLPDEQLSPTQPFSVGMPTLAKPKLTERDAW
ECCCCCEEEEECCCCCCHHHHHHCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
GFSPLDQLWCRIQFLQSDYEGMYTPPSVERPFIQYPGYNGGNDWGGGSLDPERGIFVANY
CCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCEEEEEC
TDLPMRDQLIRREEADEKGMVPLGEPGGTTDSGGPVPQAGSPYAISIKPWRNGLTGIPCT
CCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCC
RPPYGGIMAIDLATREVLWDKPLGTARNNGPFGIPSRLPFTIGTPNNGGSVITAGGLIFI
CCCCCCEEEEEEHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCEEEECCEEEE
AATTDDLIRAIDIDTGEVVWQDVLPAGGQATPMTYEVNGRQYLAIFAGGHHFMETKIGDY
EECHHHHEEEEECCCCHHHHHHHCCCCCCCCCEEEEECCCEEEEEEECCCEEEEECCCCE
LVVYSLPTPGDSSSTETLEE
EEEEECCCCCCCCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12686146 [H]