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The map label for this gene is ddc [H]

Identifier: 146284010

GI number: 146284010

Start: 3998720

End: 3999979

Strand: Direct

Name: ddc [H]

Synonym: PST_3698

Alternate gene names: 146284010

Gene position: 3998720-3999979 (Clockwise)

Preceding gene: 146284004

Following gene: 146284011

Centisome position: 87.55

GC content: 68.17

Gene sequence:

>1260_bases
GTGTATTTCCACCATCCGCGCTACGTCGCCCATCTCAACTGCCCGGTGGTGCTGCCGGCGCTGCTCGCCGAAGTGCTGGT
GTCATCGCTCAATTCCTCGCTGGACACCTGGGACCAGAGCGCCGGCGGCACGCTGATCGAACAACGCCTGATCGACTGGA
CCTGCGCGCGCATCGGCCTCGGCAATCAGGCCGACGGCGTCTTCACCAGCGGCGGCACCCAGTCCAACCTGATGGGGCTG
CTGCTGGCCCGTGAGCACGTCTGCAACCGCTTGCCCGGCCACGGCAGCAACCTCCAGCAGGGGCTACCGCCGGACGCGGG
CCGACTGCGCATCTTCGCCTCCCGCGCCAGCCACTTCAGCGTGCAGAAATCCGCCGCGCTGCTGGGGCTGGGCTACGACG
CCGTGCGCAGCATCGAAACCGACAGCGCCCAATGCATGAGCGTGCCGGCGCTGGCCCAGGCGCTGGCGGACTGTCAGCGC
CTGGGCGAGCTGCCCATGGCCGTGGTCGCCACCGCCGGCACCACCGACTTCGGCAGCATCGACCCGCTGCCGGAGATCGC
CGCGCTGTGCCAGCACTACGGCCTCTGGTTGCACGTCGATGCGGCCTATGGCGGCGGCCTGCTGGTCGCGCCGCGCTACC
GCCACTGGCTAGCCGGCATCGAACACGCCGACTCGGTCACCGTGGACTACCACAAGTCGTTCTTCCAGCCGGTCAGCTGC
AGCGGCTTCTTCGTTCGCCAGCGTCAGCACCTGAGCTACATCACCCACCACGCCGACTACCTCAACCCGCGTAGCCAGAC
CCGCGAGGGCACGCCGAACCTGGTCAACAAAAGCATCCAGACCACCCGCCGCTTCGACGCGCTGAAGCTCTGGCTGACCC
TGCGCATCCTCGGTGCCGAGCATCTCGGCGCGATGTTCGAGGAAGTCATCGACCGCGCCGCCGACACCCATCGCCTGCTC
GCCGACGACCCGGCCTTCGAGGTCTTCGCCCCGCGCCTGAGCACGCTGGTGTTCCGCTTCGTCGCCGCAGGCGTGGCGGA
CGAGCGCCTGGACGAGATCAACCGCGAGATCCGCAAGGCGATCTTACGCTCCGGCGCGGCGGTCATTGCCGCCACCGTGG
TCAAGGGCCGGCAGTACCTCAAGTTCACCCTGCTCAACCCGGAAACCACGCTGGACGACCTGCGCGCCATCGTCGAGCTG
ATTCGTGACCACGGCGCCCGCCTGCTCGACGACCGCCAACCAGTAGGAGATCGCTCATGA

Upstream 100 bases:

>100_bases
GGAGCTTGCCGCCGACTTCGAACGCGTCGATCTCGAGCGCCCGCTGGGCGACGCCGGTGCCGCGCTGCGCGAGCTGGATC
AGCTCTATCTGCGCGACGCG

Downstream 100 bases:

>100_bases
ACAAGATCTACGACTTCATAGGCATCGGCATCGGCCCGTTCAACCTTGGCCTGGCCTGCCTGGCACAGCCCATCGACGGA
CTCGACTGCCTGTTCCTCGA

Product: tyrosine decarboxylase, putative

Products: NA

Alternate protein names: DABA decarboxylase; DABA-DC [H]

Number of amino acids: Translated: 419; Mature: 419

Protein sequence:

>419_residues
MYFHHPRYVAHLNCPVVLPALLAEVLVSSLNSSLDTWDQSAGGTLIEQRLIDWTCARIGLGNQADGVFTSGGTQSNLMGL
LLAREHVCNRLPGHGSNLQQGLPPDAGRLRIFASRASHFSVQKSAALLGLGYDAVRSIETDSAQCMSVPALAQALADCQR
LGELPMAVVATAGTTDFGSIDPLPEIAALCQHYGLWLHVDAAYGGGLLVAPRYRHWLAGIEHADSVTVDYHKSFFQPVSC
SGFFVRQRQHLSYITHHADYLNPRSQTREGTPNLVNKSIQTTRRFDALKLWLTLRILGAEHLGAMFEEVIDRAADTHRLL
ADDPAFEVFAPRLSTLVFRFVAAGVADERLDEINREIRKAILRSGAAVIAATVVKGRQYLKFTLLNPETTLDDLRAIVEL
IRDHGARLLDDRQPVGDRS

Sequences:

>Translated_419_residues
MYFHHPRYVAHLNCPVVLPALLAEVLVSSLNSSLDTWDQSAGGTLIEQRLIDWTCARIGLGNQADGVFTSGGTQSNLMGL
LLAREHVCNRLPGHGSNLQQGLPPDAGRLRIFASRASHFSVQKSAALLGLGYDAVRSIETDSAQCMSVPALAQALADCQR
LGELPMAVVATAGTTDFGSIDPLPEIAALCQHYGLWLHVDAAYGGGLLVAPRYRHWLAGIEHADSVTVDYHKSFFQPVSC
SGFFVRQRQHLSYITHHADYLNPRSQTREGTPNLVNKSIQTTRRFDALKLWLTLRILGAEHLGAMFEEVIDRAADTHRLL
ADDPAFEVFAPRLSTLVFRFVAAGVADERLDEINREIRKAILRSGAAVIAATVVKGRQYLKFTLLNPETTLDDLRAIVEL
IRDHGARLLDDRQPVGDRS
>Mature_419_residues
MYFHHPRYVAHLNCPVVLPALLAEVLVSSLNSSLDTWDQSAGGTLIEQRLIDWTCARIGLGNQADGVFTSGGTQSNLMGL
LLAREHVCNRLPGHGSNLQQGLPPDAGRLRIFASRASHFSVQKSAALLGLGYDAVRSIETDSAQCMSVPALAQALADCQR
LGELPMAVVATAGTTDFGSIDPLPEIAALCQHYGLWLHVDAAYGGGLLVAPRYRHWLAGIEHADSVTVDYHKSFFQPVSC
SGFFVRQRQHLSYITHHADYLNPRSQTREGTPNLVNKSIQTTRRFDALKLWLTLRILGAEHLGAMFEEVIDRAADTHRLL
ADDPAFEVFAPRLSTLVFRFVAAGVADERLDEINREIRKAILRSGAAVIAATVVKGRQYLKFTLLNPETTLDDLRAIVEL
IRDHGARLLDDRQPVGDRS

Specific function: Unknown

COG id: COG0076

COG function: function code E; Glutamate decarboxylase and related PLP-dependent proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the group II decarboxylase family [H]

Homologues:

Organism=Homo sapiens, GI197276620, Length=418, Percent_Identity=28.7081339712919, Blast_Score=186, Evalue=3e-47,
Organism=Homo sapiens, GI4503875, Length=418, Percent_Identity=28.7081339712919, Blast_Score=186, Evalue=3e-47,
Organism=Homo sapiens, GI197383062, Length=414, Percent_Identity=28.9855072463768, Blast_Score=185, Evalue=5e-47,
Organism=Homo sapiens, GI194294551, Length=381, Percent_Identity=32.8083989501312, Blast_Score=181, Evalue=1e-45,
Organism=Homo sapiens, GI58331246, Length=419, Percent_Identity=28.8782816229117, Blast_Score=176, Evalue=3e-44,
Organism=Homo sapiens, GI92110055, Length=425, Percent_Identity=28.9411764705882, Blast_Score=166, Evalue=4e-41,
Organism=Homo sapiens, GI4503281, Length=359, Percent_Identity=28.6908077994429, Blast_Score=154, Evalue=2e-37,
Organism=Homo sapiens, GI132814448, Length=359, Percent_Identity=28.6908077994429, Blast_Score=154, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI17555682, Length=416, Percent_Identity=29.3269230769231, Blast_Score=191, Evalue=5e-49,
Organism=Caenorhabditis elegans, GI71993062, Length=416, Percent_Identity=29.3269230769231, Blast_Score=191, Evalue=6e-49,
Organism=Caenorhabditis elegans, GI71993058, Length=332, Percent_Identity=31.6265060240964, Blast_Score=174, Evalue=7e-44,
Organism=Caenorhabditis elegans, GI17534819, Length=420, Percent_Identity=27.6190476190476, Blast_Score=150, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI17534817, Length=420, Percent_Identity=27.6190476190476, Blast_Score=150, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI71981211, Length=453, Percent_Identity=23.3995584988962, Blast_Score=126, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI71981217, Length=462, Percent_Identity=22.9437229437229, Blast_Score=123, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI133931025, Length=409, Percent_Identity=25.9168704156479, Blast_Score=111, Evalue=7e-25,
Organism=Caenorhabditis elegans, GI17551992, Length=444, Percent_Identity=21.8468468468468, Blast_Score=101, Evalue=9e-22,
Organism=Drosophila melanogaster, GI17136594, Length=378, Percent_Identity=31.4814814814815, Blast_Score=187, Evalue=9e-48,
Organism=Drosophila melanogaster, GI24652373, Length=423, Percent_Identity=29.7872340425532, Blast_Score=153, Evalue=2e-37,
Organism=Drosophila melanogaster, GI21356415, Length=384, Percent_Identity=30.9895833333333, Blast_Score=150, Evalue=1e-36,
Organism=Drosophila melanogaster, GI24657193, Length=389, Percent_Identity=30.0771208226221, Blast_Score=147, Evalue=1e-35,
Organism=Drosophila melanogaster, GI24657185, Length=389, Percent_Identity=30.0771208226221, Blast_Score=147, Evalue=1e-35,
Organism=Drosophila melanogaster, GI24657188, Length=389, Percent_Identity=30.0771208226221, Blast_Score=147, Evalue=1e-35,
Organism=Drosophila melanogaster, GI24586044, Length=423, Percent_Identity=26.241134751773, Blast_Score=143, Evalue=2e-34,
Organism=Drosophila melanogaster, GI28573972, Length=427, Percent_Identity=26.9320843091335, Blast_Score=130, Evalue=1e-30,
Organism=Drosophila melanogaster, GI17136190, Length=405, Percent_Identity=25.1851851851852, Blast_Score=128, Evalue=9e-30,
Organism=Drosophila melanogaster, GI221476190, Length=411, Percent_Identity=26.0340632603406, Blast_Score=125, Evalue=4e-29,
Organism=Drosophila melanogaster, GI24585143, Length=411, Percent_Identity=26.0340632603406, Blast_Score=125, Evalue=4e-29,
Organism=Drosophila melanogaster, GI24585139, Length=411, Percent_Identity=26.0340632603406, Blast_Score=125, Evalue=5e-29,
Organism=Drosophila melanogaster, GI24585135, Length=383, Percent_Identity=25.5874673629243, Blast_Score=122, Evalue=5e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002129
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- InterPro:   IPR021115 [H]

Pfam domain/function: PF00282 Pyridoxal_deC [H]

EC number: =4.1.1.86 [H]

Molecular weight: Translated: 46042; Mature: 46042

Theoretical pI: Translated: 6.98; Mature: 6.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYFHHPRYVAHLNCPVVLPALLAEVLVSSLNSSLDTWDQSAGGTLIEQRLIDWTCARIGL
CCCCCCCEEEECCCHHHHHHHHHHHHHHHHCCHHHHHCCCCCCHHHHHHHHHHHHHHCCC
GNQADGVFTSGGTQSNLMGLLLAREHVCNRLPGHGSNLQQGLPPDAGRLRIFASRASHFS
CCCCCCCEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEECCHHHH
VQKSAALLGLGYDAVRSIETDSAQCMSVPALAQALADCQRLGELPMAVVATAGTTDFGSI
HHHHHHHHCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCC
DPLPEIAALCQHYGLWLHVDAAYGGGLLVAPRYRHWLAGIEHADSVTVDYHKSFFQPVSC
CCHHHHHHHHHHCCEEEEEECCCCCCEEECCHHHHHHHCCCCCCCEEEHHHHHHCCCCCC
SGFFVRQRQHLSYITHHADYLNPRSQTREGTPNLVNKSIQTTRRFDALKLWLTLRILGAE
CHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HLGAMFEEVIDRAADTHRLLADDPAFEVFAPRLSTLVFRFVAAGVADERLDEINREIRKA
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
ILRSGAAVIAATVVKGRQYLKFTLLNPETTLDDLRAIVELIRDHGARLLDDRQPVGDRS
HHHCCHHHHHHHHHHCCEEEEEEEECCCCCHHHHHHHHHHHHHCCCHHHCCCCCCCCCC
>Mature Secondary Structure
MYFHHPRYVAHLNCPVVLPALLAEVLVSSLNSSLDTWDQSAGGTLIEQRLIDWTCARIGL
CCCCCCCEEEECCCHHHHHHHHHHHHHHHHCCHHHHHCCCCCCHHHHHHHHHHHHHHCCC
GNQADGVFTSGGTQSNLMGLLLAREHVCNRLPGHGSNLQQGLPPDAGRLRIFASRASHFS
CCCCCCCEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEECCHHHH
VQKSAALLGLGYDAVRSIETDSAQCMSVPALAQALADCQRLGELPMAVVATAGTTDFGSI
HHHHHHHHCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCC
DPLPEIAALCQHYGLWLHVDAAYGGGLLVAPRYRHWLAGIEHADSVTVDYHKSFFQPVSC
CCHHHHHHHHHHCCEEEEEECCCCCCEEECCHHHHHHHCCCCCCCEEEHHHHHHCCCCCC
SGFFVRQRQHLSYITHHADYLNPRSQTREGTPNLVNKSIQTTRRFDALKLWLTLRILGAE
CHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HLGAMFEEVIDRAADTHRLLADDPAFEVFAPRLSTLVFRFVAAGVADERLDEINREIRKA
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
ILRSGAAVIAATVVKGRQYLKFTLLNPETTLDDLRAIVELIRDHGARLLDDRQPVGDRS
HHHCCHHHHHHHHHHCCEEEEEEEECCCCCHHHHHHHHHHHHHCCCHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800; 9514614 [H]