Click here to switch to the map view.

The map label for this gene is comL [C]

Identifier: 146283957

GI number: 146283957

Start: 3932283

End: 3933407

Strand: Direct

Name: comL [C]

Synonym: PST_3643

Alternate gene names: 146283957

Gene position: 3932283-3933407 (Clockwise)

Preceding gene: 146283953

Following gene: 146283958

Centisome position: 86.09

GC content: 63.47

Gene sequence:

>1125_bases
ATGGCGGAGCGGCCTTTGGTTTCGGCTACACGCTTGTGTTTAAATACGGCGTCTTTGTCCCGGCGCACCGGGGCGCCCAT
CATAACAGGACGGCTCCGCGCGAGACAGCCAGCCGTCACAGGGACGCAAGCCGCCATGCAAGTGAAACACCTGCTGCTGA
TCGCCATTTTCGCCCTTACCGCCGCCTGTTCATCCAACGAAACCGTCGACGAAAACCTGGGCGAGGTCGAGCTGTACCAG
CAAGCACAGGCCGATCTGGACAACAAGAGCTATACCAGCGCCATCAGCAAGCTCAAGGCGCTGGAGTCGCGTTACCCGTT
CGGTCGTTTCGCCGAGCAGGCGCAGCTCGAGCTGATCTACGCCTATTACCGCAACGCCGAGCCGGAAGCTGCACGCTCGG
CTGCCGAGCGCTTCATCCGCCTGCATCCGCAGCACCCGAACGTCGACTACGCCTACTACCTCAAGGGCCTGGCCTCGTTC
GATCAGGACCGCGGCCTGCTCGCTCGCTTCTTGCCGCTGGACATGACCAAGCGCGACCCGGGCGCTGCCCGCGACTCGTT
CAACGAATTCGCCCAGCTCACCAGCCGCTATCCGAACAGCCGTTATTCGCCGGATGCCAAGGCGCGCATGATCTACCTGC
GCAACCTCCTGGCAGCCAACGAGATTCACGTCGCTCACTACTACCTCAAGCGCCAGGCCTACGTGGCCGCCGCCAACCGC
GGGCGCTATGTGGTGGAAAACTTCCAGGGCACACCGGCCGTGGCGGATGGTCTGGCTGTGATGACCGAGGCCTACCAGCG
CCTCGGCCTCGATGACCTCGCCGATGCCAGCCTCAAGACCCTTCAGCTCAACTACCCGGATCATGCCACCCTCGAGGACG
GCAAGTTCACCCCCATCGAGCGCGAAGAGGACACCCGCAGCTGGTTGAGCAAGGCCACGCTCGGCCTGATCGAAGGCGAA
GCGCCGCGTCCCGACACTTCCCGTGCCAACCGTGACGTGTTGCGCCAGTACGAGAACGCTGCGCGTGATCTGCCGGAAGA
ACTGCGCCCCGTACTCAAGGAAGTGGAACAGCAGGAGCCGAAGCGCTCCTGGTGGAGCCGCCTGACCTTCGGCCTGTTCG
ACTGA

Upstream 100 bases:

>100_bases
GTTGAATGGCCTGTTTGGAGATCGTGGACATACGGCGAGATAGATTCGTCAGAGAGAGGCGAGCGGCATCCGTTGCTGAT
GGATGCCCGGAGGACCGCAG

Downstream 100 bases:

>100_bases
AATGGGCTGACCATGCGCCGCTACGTCGAGCCCTGTGCTCGTCACCGTCGGCGCACCAGGCCAGGACCAGCCCTGGCTAG
ACCGGTGGCCGGTCGCCACG

Product: competence protein ComL

Products: NA

Alternate protein names: ORFY [H]

Number of amino acids: Translated: 374; Mature: 373

Protein sequence:

>374_residues
MAERPLVSATRLCLNTASLSRRTGAPIITGRLRARQPAVTGTQAAMQVKHLLLIAIFALTAACSSNETVDENLGEVELYQ
QAQADLDNKSYTSAISKLKALESRYPFGRFAEQAQLELIYAYYRNAEPEAARSAAERFIRLHPQHPNVDYAYYLKGLASF
DQDRGLLARFLPLDMTKRDPGAARDSFNEFAQLTSRYPNSRYSPDAKARMIYLRNLLAANEIHVAHYYLKRQAYVAAANR
GRYVVENFQGTPAVADGLAVMTEAYQRLGLDDLADASLKTLQLNYPDHATLEDGKFTPIEREEDTRSWLSKATLGLIEGE
APRPDTSRANRDVLRQYENAARDLPEELRPVLKEVEQQEPKRSWWSRLTFGLFD

Sequences:

>Translated_374_residues
MAERPLVSATRLCLNTASLSRRTGAPIITGRLRARQPAVTGTQAAMQVKHLLLIAIFALTAACSSNETVDENLGEVELYQ
QAQADLDNKSYTSAISKLKALESRYPFGRFAEQAQLELIYAYYRNAEPEAARSAAERFIRLHPQHPNVDYAYYLKGLASF
DQDRGLLARFLPLDMTKRDPGAARDSFNEFAQLTSRYPNSRYSPDAKARMIYLRNLLAANEIHVAHYYLKRQAYVAAANR
GRYVVENFQGTPAVADGLAVMTEAYQRLGLDDLADASLKTLQLNYPDHATLEDGKFTPIEREEDTRSWLSKATLGLIEGE
APRPDTSRANRDVLRQYENAARDLPEELRPVLKEVEQQEPKRSWWSRLTFGLFD
>Mature_373_residues
AERPLVSATRLCLNTASLSRRTGAPIITGRLRARQPAVTGTQAAMQVKHLLLIAIFALTAACSSNETVDENLGEVELYQQ
AQADLDNKSYTSAISKLKALESRYPFGRFAEQAQLELIYAYYRNAEPEAARSAAERFIRLHPQHPNVDYAYYLKGLASFD
QDRGLLARFLPLDMTKRDPGAARDSFNEFAQLTSRYPNSRYSPDAKARMIYLRNLLAANEIHVAHYYLKRQAYVAAANRG
RYVVENFQGTPAVADGLAVMTEAYQRLGLDDLADASLKTLQLNYPDHATLEDGKFTPIEREEDTRSWLSKATLGLIEGEA
PRPDTSRANRDVLRQYENAARDLPEELRPVLKEVEQQEPKRSWWSRLTFGLFD

Specific function: Unknown

COG id: COG4105

COG function: function code R; DNA uptake lipoprotein

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0169 (ComL) family [H]

Homologues:

Organism=Escherichia coli, GI1788947, Length=240, Percent_Identity=40.4166666666667, Blast_Score=181, Evalue=6e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017689 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 42240; Mature: 42109

Theoretical pI: Translated: 7.64; Mature: 7.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAERPLVSATRLCLNTASLSRRTGAPIITGRLRARQPAVTGTQAAMQVKHLLLIAIFALT
CCCCCHHHHHHHHHHHHHHHHHCCCCEEECCHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
AACSSNETVDENLGEVELYQQAQADLDNKSYTSAISKLKALESRYPFGRFAEQAQLELIY
HHCCCCCCHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
AYYRNAEPEAARSAAERFIRLHPQHPNVDYAYYLKGLASFDQDRGLLARFLPLDMTKRDP
HHHHCCCHHHHHHHHHHHHEECCCCCCCCHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCC
GAARDSFNEFAQLTSRYPNSRYSPDAKARMIYLRNLLAANEIHVAHYYLKRQAYVAAANR
CCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCC
GRYVVENFQGTPAVADGLAVMTEAYQRLGLDDLADASLKTLQLNYPDHATLEDGKFTPIE
CCEEEECCCCCCHHHHHHHHHHHHHHHCCCHHHHCCCEEEEEECCCCCCCCCCCCCCCCC
REEDTRSWLSKATLGLIEGEAPRPDTSRANRDVLRQYENAARDLPEELRPVLKEVEQQEP
CCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCH
KRSWWSRLTFGLFD
HHHHHHHHHHCCCC
>Mature Secondary Structure 
AERPLVSATRLCLNTASLSRRTGAPIITGRLRARQPAVTGTQAAMQVKHLLLIAIFALT
CCCCHHHHHHHHHHHHHHHHHCCCCEEECCHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
AACSSNETVDENLGEVELYQQAQADLDNKSYTSAISKLKALESRYPFGRFAEQAQLELIY
HHCCCCCCHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
AYYRNAEPEAARSAAERFIRLHPQHPNVDYAYYLKGLASFDQDRGLLARFLPLDMTKRDP
HHHHCCCHHHHHHHHHHHHEECCCCCCCCHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCC
GAARDSFNEFAQLTSRYPNSRYSPDAKARMIYLRNLLAANEIHVAHYYLKRQAYVAAANR
CCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCC
GRYVVENFQGTPAVADGLAVMTEAYQRLGLDDLADASLKTLQLNYPDHATLEDGKFTPIE
CCEEEECCCCCCHHHHHHHHHHHHHHHCCCHHHHCCCEEEEEECCCCCCCCCCCCCCCCC
REEDTRSWLSKATLGLIEGEAPRPDTSRANRDVLRQYENAARDLPEELRPVLKEVEQQEP
CCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCH
KRSWWSRLTFGLFD
HHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8097014; 10984043 [H]