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The map label for this gene is phhC [H]

Identifier: 146283881

GI number: 146283881

Start: 3856749

End: 3857945

Strand: Direct

Name: phhC [H]

Synonym: PST_3564

Alternate gene names: 146283881

Gene position: 3856749-3857945 (Clockwise)

Preceding gene: 146283880

Following gene: 146283882

Centisome position: 84.44

GC content: 69.26

Gene sequence:

>1197_bases
ATGCACTTCGGCCAGATTCCCCGCGTGCCCGGCGACCCGATCCTCGGCCTGATGGACCTGTATCGCGCCGACACCAACCC
GGCCAAGCTCGACCTCGGCGTCGGCGTCTACAAGGACGCCCAGGGCCTGACGCCGATCCCGCGCGCGGTGAAGCTGGCCG
AGCAGCGCCTGGTGGACAGTGAGCAGACCAAGAGCTACATCGGCGGCCACGGCGACGTCCCGTTCGGCGCCCTATTACTA
CGTCAGGTGCTCGGCAGCCGCGCCATTGCCCTCGGCGAGCAGCGCGCCGGCTGCACCCAGGCGCCGGGCGGCACCGGCGC
GTTGCGCCTGGCCGGCGAGTTCATCGCCAAATGCCTGCCAGGGCGCAGCATCTGGCTGAGCGATCCCACCTGGCCGATTC
ACGAAACCCTGTTCGCCGCCGCCGGCCTGCGCGTGCAGCACTACCCCTACGTCGGCGCCGACAACCGCCTCGATGTCGAC
GGCATGCTCGCCACGCTGCAACAGATGCCGCCTGGCGACGTGGTGCTGCTGCACGCCTGCTGCCACAACCCCACCGGCTT
CGACCTGAATCACGACGACTGGCTGCGGGTGCTGGACGTGGTGCGTGCGCGCGAACTGCTGCCGCTGTTCGACTTCGCCT
ACCAGGGCTTCGGCGACGGACTGGAAGAGGACGCCTGGGCAGTACGGCTGTTCGCCGAAACGCTGCCGGAAATGCTCATC
ACCAGTTCCTGCTCGAAGAACTTCGGCCTCTACCGCGAACGCACCGGAGCGCTGATCGCCGTCACCAGCGATGCCGAGCG
CCTGCTCGACGTGCGCAGCCAGCTCGCGTCGCTGGCCCGCAACCTCTGGTCGACGCCACCGGCCCACGGCGCCGCGGTGG
TGGCGACGATCCTGGCCGATGAGCCCCTGCGGCAGATCTGGCAGGACGAGGTGGAGAGCATGCGCAGACGCATCGCCAGT
CTGCGGCAGGGGCTGGTCGAGGCGCTGACGCCCTATGGGCTGGCCGAGCGCTTCGCGCACATCGCCCGGCAGCGGGGAAT
GTTCTCCTATACCGGCCTGACCGCCGAGCAGGTACGCCGGCTGCGCGCCGAAGATTCGGTGTATCTGGTGGAAAGCGGTC
GCGCCAACGTCGCCGGGCTGGATGCCGAGCGCCTGGACGATCTGGCCAGGGCCATTGCACGGGTGGTGCAGGGCTGA

Upstream 100 bases:

>100_bases
TCACCTGGTGGAGCCACGAGATGCGCGGCCTGCACCGCAACGACTTCATCATGGCCGCCCGCACCGACCAGCTCGCCGCC
AGCGCGGAGGGCCGCAAGTA

Downstream 100 bases:

>100_bases
ACGATGTGAAGGTGCGCGCCGGTGACGCCGCTTCTGGCGACGCCGCCGGGTGCGCCGGAGCGAGAGAGCAGTGGCGCGGC
TCGTGACCACGCGACTGGCT

Product: aromatic amino acid aminotransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 398; Mature: 398

Protein sequence:

>398_residues
MHFGQIPRVPGDPILGLMDLYRADTNPAKLDLGVGVYKDAQGLTPIPRAVKLAEQRLVDSEQTKSYIGGHGDVPFGALLL
RQVLGSRAIALGEQRAGCTQAPGGTGALRLAGEFIAKCLPGRSIWLSDPTWPIHETLFAAAGLRVQHYPYVGADNRLDVD
GMLATLQQMPPGDVVLLHACCHNPTGFDLNHDDWLRVLDVVRARELLPLFDFAYQGFGDGLEEDAWAVRLFAETLPEMLI
TSSCSKNFGLYRERTGALIAVTSDAERLLDVRSQLASLARNLWSTPPAHGAAVVATILADEPLRQIWQDEVESMRRRIAS
LRQGLVEALTPYGLAERFAHIARQRGMFSYTGLTAEQVRRLRAEDSVYLVESGRANVAGLDAERLDDLARAIARVVQG

Sequences:

>Translated_398_residues
MHFGQIPRVPGDPILGLMDLYRADTNPAKLDLGVGVYKDAQGLTPIPRAVKLAEQRLVDSEQTKSYIGGHGDVPFGALLL
RQVLGSRAIALGEQRAGCTQAPGGTGALRLAGEFIAKCLPGRSIWLSDPTWPIHETLFAAAGLRVQHYPYVGADNRLDVD
GMLATLQQMPPGDVVLLHACCHNPTGFDLNHDDWLRVLDVVRARELLPLFDFAYQGFGDGLEEDAWAVRLFAETLPEMLI
TSSCSKNFGLYRERTGALIAVTSDAERLLDVRSQLASLARNLWSTPPAHGAAVVATILADEPLRQIWQDEVESMRRRIAS
LRQGLVEALTPYGLAERFAHIARQRGMFSYTGLTAEQVRRLRAEDSVYLVESGRANVAGLDAERLDDLARAIARVVQG
>Mature_398_residues
MHFGQIPRVPGDPILGLMDLYRADTNPAKLDLGVGVYKDAQGLTPIPRAVKLAEQRLVDSEQTKSYIGGHGDVPFGALLL
RQVLGSRAIALGEQRAGCTQAPGGTGALRLAGEFIAKCLPGRSIWLSDPTWPIHETLFAAAGLRVQHYPYVGADNRLDVD
GMLATLQQMPPGDVVLLHACCHNPTGFDLNHDDWLRVLDVVRARELLPLFDFAYQGFGDGLEEDAWAVRLFAETLPEMLI
TSSCSKNFGLYRERTGALIAVTSDAERLLDVRSQLASLARNLWSTPPAHGAAVVATILADEPLRQIWQDEVESMRRRIAS
LRQGLVEALTPYGLAERFAHIARQRGMFSYTGLTAEQVRRLRAEDSVYLVESGRANVAGLDAERLDDLARAIARVVQG

Specific function: Unknown

COG id: COG1448

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4504067, Length=403, Percent_Identity=38.9578163771712, Blast_Score=278, Evalue=7e-75,
Organism=Homo sapiens, GI73486658, Length=392, Percent_Identity=39.030612244898, Blast_Score=266, Evalue=2e-71,
Organism=Homo sapiens, GI117414139, Length=389, Percent_Identity=26.9922879177378, Blast_Score=154, Evalue=1e-37,
Organism=Escherichia coli, GI1787159, Length=395, Percent_Identity=47.5949367088608, Blast_Score=377, Evalue=1e-106,
Organism=Escherichia coli, GI1790488, Length=396, Percent_Identity=42.6767676767677, Blast_Score=313, Evalue=1e-86,
Organism=Caenorhabditis elegans, GI71981858, Length=397, Percent_Identity=39.0428211586902, Blast_Score=309, Evalue=2e-84,
Organism=Caenorhabditis elegans, GI25147133, Length=390, Percent_Identity=40.5128205128205, Blast_Score=298, Evalue=3e-81,
Organism=Caenorhabditis elegans, GI17569539, Length=400, Percent_Identity=35.25, Blast_Score=264, Evalue=7e-71,
Organism=Caenorhabditis elegans, GI17569537, Length=383, Percent_Identity=30.2872062663185, Blast_Score=195, Evalue=3e-50,
Organism=Caenorhabditis elegans, GI17550384, Length=268, Percent_Identity=32.089552238806, Blast_Score=162, Evalue=3e-40,
Organism=Caenorhabditis elegans, GI25147136, Length=208, Percent_Identity=37.9807692307692, Blast_Score=155, Evalue=3e-38,
Organism=Saccharomyces cerevisiae, GI6323055, Length=405, Percent_Identity=37.037037037037, Blast_Score=277, Evalue=2e-75,
Organism=Saccharomyces cerevisiae, GI6322743, Length=434, Percent_Identity=31.1059907834101, Blast_Score=214, Evalue=1e-56,
Organism=Drosophila melanogaster, GI19922362, Length=400, Percent_Identity=37.75, Blast_Score=274, Evalue=8e-74,
Organism=Drosophila melanogaster, GI24654046, Length=400, Percent_Identity=37.75, Blast_Score=274, Evalue=9e-74,
Organism=Drosophila melanogaster, GI24580972, Length=398, Percent_Identity=38.1909547738693, Blast_Score=273, Evalue=2e-73,
Organism=Drosophila melanogaster, GI24580970, Length=398, Percent_Identity=38.1909547738693, Blast_Score=273, Evalue=2e-73,
Organism=Drosophila melanogaster, GI19920542, Length=391, Percent_Identity=38.618925831202, Blast_Score=271, Evalue=6e-73,

Paralogues:

None

Copy number: 6,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000796
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.57 [H]

Molecular weight: Translated: 43566; Mature: 43566

Theoretical pI: Translated: 6.06; Mature: 6.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHFGQIPRVPGDPILGLMDLYRADTNPAKLDLGVGVYKDAQGLTPIPRAVKLAEQRLVDS
CCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEECCCEECCCCCCCCCHHHHHHHHHHHHCH
EQTKSYIGGHGDVPFGALLLRQVLGSRAIALGEQRAGCTQAPGGTGALRLAGEFIAKCLP
HHHHHHCCCCCCCCHHHHHHHHHHCCHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCC
GRSIWLSDPTWPIHETLFAAAGLRVQHYPYVGADNRLDVDGMLATLQQMPPGDVVLLHAC
CCEEEECCCCCHHHHHHHHHHCCEEEECCCCCCCCCCCHHHHHHHHHHCCCCCEEEEEHH
CHNPTGFDLNHDDWLRVLDVVRARELLPLFDFAYQGFGDGLEEDAWAVRLFAETLPEMLI
HCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
TSSCSKNFGLYRERTGALIAVTSDAERLLDVRSQLASLARNLWSTPPAHGAAVVATILAD
HHHHHHCCCCHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCC
EPLRQIWQDEVESMRRRIASLRQGLVEALTPYGLAERFAHIARQRGMFSYTGLTAEQVRR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHH
LRAEDSVYLVESGRANVAGLDAERLDDLARAIARVVQG
HHCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MHFGQIPRVPGDPILGLMDLYRADTNPAKLDLGVGVYKDAQGLTPIPRAVKLAEQRLVDS
CCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEECCCEECCCCCCCCCHHHHHHHHHHHHCH
EQTKSYIGGHGDVPFGALLLRQVLGSRAIALGEQRAGCTQAPGGTGALRLAGEFIAKCLP
HHHHHHCCCCCCCCHHHHHHHHHHCCHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCC
GRSIWLSDPTWPIHETLFAAAGLRVQHYPYVGADNRLDVDGMLATLQQMPPGDVVLLHAC
CCEEEECCCCCHHHHHHHHHHCCEEEECCCCCCCCCCCHHHHHHHHHHCCCCCEEEEEHH
CHNPTGFDLNHDDWLRVLDVVRARELLPLFDFAYQGFGDGLEEDAWAVRLFAETLPEMLI
HCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
TSSCSKNFGLYRERTGALIAVTSDAERLLDVRSQLASLARNLWSTPPAHGAAVVATILAD
HHHHHHCCCCHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCC
EPLRQIWQDEVESMRRRIASLRQGLVEALTPYGLAERFAHIARQRGMFSYTGLTAEQVRR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHH
LRAEDSVYLVESGRANVAGLDAERLDDLARAIARVVQG
HHCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8108417; 10984043 [H]