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The map label for this gene is gluQ [H]

Identifier: 146283610

GI number: 146283610

Start: 3559690

End: 3560595

Strand: Direct

Name: gluQ [H]

Synonym: PST_3290

Alternate gene names: 146283610

Gene position: 3559690-3560595 (Clockwise)

Preceding gene: 146283609

Following gene: 146283611

Centisome position: 77.94

GC content: 67.44

Gene sequence:

>906_bases
ATGTCCTCCTCCGCCCCGCCCCAGCCCGCACGCTACATCGGTCGCTTTGCACCGACCCCCAGCGGCTACCTGCACTTCGG
CTCGCTGATCGCGGCCCTCGCTTCCTATCTCGACGCCCGTTCGGTCGGCGGCCTTTGGTTGCTGCGCATGGAAGACATCG
ATCCGCCACGGGAGATGCCCGGCGCCCAGCGGGCCATCGTCGAGACGCTGCAGAGCTACGGCTTCGAATGGGACGGCGAC
ATGCTGCGCCAGAGCGAACGTCACGCTGCGTATCGGGACGCCATCGAACGGCTGCTGGATGAAGGCCTGGCGTATGCGTG
CACCTGCTCGCGCAAGCAGCTCGAAGGCTACCCGGGCCCCTACCCCGGCTTCTGCCGCGCCGCCGGTCGCAGCCTCGAGG
ATGCTGCCATCCGCCTGCGCGTACCCGATCGTGAATACGTCTTCATCGATCGTGTGCAAGGCGAGTTCCGCCAGCATCTG
GGCCGCGAGGTCGGCGATTTTGTCATTCGCCGCCGCGACGGCCTGATTGCCTATCAGCTGGCCGTGGTACTGGATGACGC
CTGGCAAGGTGTCACCGATGTGGTGCGTGGCGCCGACCTGCTCGATTCAACGCCGCGCCAGCTTTATCTGCAGGAAGTCC
TCGGCCTGCCACAACCACGCTACCTGCACCTGCCGCTGATCATCCAGCCGGACGGACACAAGCTCGGCAAGAGCTATCGC
TCGCCACCGCTGCAAGCCCAGGAGGCCAGCCCACTGCTGCTTCGCGCGCTGCGCGCCCTTGGCCAGCAACCGCCAGCGGA
ACTGGACGGCGCGCTGCCGGCGGACATTCTCGGCTGGGCCGTCGCCCACTGGAATGCAGCACGCATCCCGCGGGTCCGCA
CCCTCGCCGAAGCCCAGCTGCGCTGA

Upstream 100 bases:

>100_bases
TCGGTTCCTGATCCCGAACGGGGCGCTACGGCGCCCCGCTTCATTTCCAGGCCCTGCACCGTTTCATCCGCCTCGCCATC
ACCGATCGCGCCGGCCCGCC

Downstream 100 bases:

>100_bases
GCCACGCATGGATCGAACCACCCGAGGCGAGCTTTTGCCTGCCGCTGGTGGCTTGCCGCGTGCCGCTGCTCTACCATCGC
CCTCACTTCCGACACGAGAC

Product: glutamyl-Q tRNA(Asp) synthetase

Products: NA

Alternate protein names: Glu-Q-RSs [H]

Number of amino acids: Translated: 301; Mature: 300

Protein sequence:

>301_residues
MSSSAPPQPARYIGRFAPTPSGYLHFGSLIAALASYLDARSVGGLWLLRMEDIDPPREMPGAQRAIVETLQSYGFEWDGD
MLRQSERHAAYRDAIERLLDEGLAYACTCSRKQLEGYPGPYPGFCRAAGRSLEDAAIRLRVPDREYVFIDRVQGEFRQHL
GREVGDFVIRRRDGLIAYQLAVVLDDAWQGVTDVVRGADLLDSTPRQLYLQEVLGLPQPRYLHLPLIIQPDGHKLGKSYR
SPPLQAQEASPLLLRALRALGQQPPAELDGALPADILGWAVAHWNAARIPRVRTLAEAQLR

Sequences:

>Translated_301_residues
MSSSAPPQPARYIGRFAPTPSGYLHFGSLIAALASYLDARSVGGLWLLRMEDIDPPREMPGAQRAIVETLQSYGFEWDGD
MLRQSERHAAYRDAIERLLDEGLAYACTCSRKQLEGYPGPYPGFCRAAGRSLEDAAIRLRVPDREYVFIDRVQGEFRQHL
GREVGDFVIRRRDGLIAYQLAVVLDDAWQGVTDVVRGADLLDSTPRQLYLQEVLGLPQPRYLHLPLIIQPDGHKLGKSYR
SPPLQAQEASPLLLRALRALGQQPPAELDGALPADILGWAVAHWNAARIPRVRTLAEAQLR
>Mature_300_residues
SSSAPPQPARYIGRFAPTPSGYLHFGSLIAALASYLDARSVGGLWLLRMEDIDPPREMPGAQRAIVETLQSYGFEWDGDM
LRQSERHAAYRDAIERLLDEGLAYACTCSRKQLEGYPGPYPGFCRAAGRSLEDAAIRLRVPDREYVFIDRVQGEFRQHLG
REVGDFVIRRRDGLIAYQLAVVLDDAWQGVTDVVRGADLLDSTPRQLYLQEVLGLPQPRYLHLPLIIQPDGHKLGKSYRS
PPLQAQEASPLLLRALRALGQQPPAELDGALPADILGWAVAHWNAARIPRVRTLAEAQLR

Specific function: Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble positi

COG id: COG0008

COG function: function code J; Glutamyl- and glutaminyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily [H]

Homologues:

Organism=Homo sapiens, GI134288884, Length=248, Percent_Identity=37.5, Blast_Score=134, Evalue=7e-32,
Organism=Escherichia coli, GI226510925, Length=283, Percent_Identity=49.1166077738516, Blast_Score=266, Evalue=8e-73,
Organism=Escherichia coli, GI1788743, Length=240, Percent_Identity=37.9166666666667, Blast_Score=153, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI71993394, Length=248, Percent_Identity=33.8709677419355, Blast_Score=120, Evalue=1e-27,
Organism=Saccharomyces cerevisiae, GI6324540, Length=256, Percent_Identity=33.203125, Blast_Score=142, Evalue=9e-35,
Organism=Drosophila melanogaster, GI24665321, Length=248, Percent_Identity=36.6935483870968, Blast_Score=144, Evalue=8e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022380
- InterPro:   IPR000924
- InterPro:   IPR020058
- InterPro:   IPR014729 [H]

Pfam domain/function: PF00749 tRNA-synt_1c [H]

EC number: NA

Molecular weight: Translated: 33571; Mature: 33440

Theoretical pI: Translated: 7.13; Mature: 7.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSSAPPQPARYIGRFAPTPSGYLHFGSLIAALASYLDARSVGGLWLLRMEDIDPPREMP
CCCCCCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHCC
GAQRAIVETLQSYGFEWDGDMLRQSERHAAYRDAIERLLDEGLAYACTCSRKQLEGYPGP
CHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHCCCCCC
YPGFCRAAGRSLEDAAIRLRVPDREYVFIDRVQGEFRQHLGREVGDFVIRRRDGLIAYQL
CCHHHHHHCCCCCCCEEEEECCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
AVVLDDAWQGVTDVVRGADLLDSTPRQLYLQEVLGLPQPRYLHLPLIIQPDGHKLGKSYR
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCEEEEEEEECCCCHHHHHHHC
SPPLQAQEASPLLLRALRALGQQPPAELDGALPADILGWAVAHWNAARIPRVRTLAEAQL
CCCCCCCCCCHHHHHHHHHHCCCCCHHHCCCCCHHHHHHHHHHCCHHCCCHHHHHHHHHC
R
C
>Mature Secondary Structure 
SSSAPPQPARYIGRFAPTPSGYLHFGSLIAALASYLDARSVGGLWLLRMEDIDPPREMP
CCCCCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHCC
GAQRAIVETLQSYGFEWDGDMLRQSERHAAYRDAIERLLDEGLAYACTCSRKQLEGYPGP
CHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHCCCCCC
YPGFCRAAGRSLEDAAIRLRVPDREYVFIDRVQGEFRQHLGREVGDFVIRRRDGLIAYQL
CCHHHHHHCCCCCCCEEEEECCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
AVVLDDAWQGVTDVVRGADLLDSTPRQLYLQEVLGLPQPRYLHLPLIIQPDGHKLGKSYR
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCEEEEEEEECCCCHHHHHHHC
SPPLQAQEASPLLLRALRALGQQPPAELDGALPADILGWAVAHWNAARIPRVRTLAEAQL
CCCCCCCCCCHHHHHHHHHHCCCCCHHHCCCCCHHHHHHHHHHCCHHCCCHHHHHHHHHC
R
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA