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The map label for this gene is cueR [H]

Identifier: 146283546

GI number: 146283546

Start: 3477843

End: 3478241

Strand: Direct

Name: cueR [H]

Synonym: PST_3221

Alternate gene names: 146283546

Gene position: 3477843-3478241 (Clockwise)

Preceding gene: 146283545

Following gene: 146283547

Centisome position: 76.14

GC content: 62.66

Gene sequence:

>399_bases
ATGGCTAAACAGACCTACAGCATTTCCGACCTGGCCAACGAGCTGGACATCACCACCCGCGCCATCCGTTTCTATGAAGA
ACAGGGCATGCTCACGCCAACCCGCCGCGGCCAGGAGCGCATCTATTCGCCCAAGGATCGCGTCGCGCTGAAGCTGATCC
TGCGCGGCAAGCGCATCGGCTTCTCGCTGGCCGAATGCAAGACCCTGATCGAACTCTACGACCCCAAGGCCGGCAACCAG
AAGCAGCTGAACATCATGCTGCAGATGATCGCCGAGCGGCGCCAGCAGCTGGAGCAGCAGCTGCTCGACATCCAGCAGAT
GCAGCTGGAGCTGGACACCGCCGAGGAGCGCTGCCGCACCGCTCTGGAAAGCACCCTGGCCAAGCAAGCCGCCAGCTGA

Upstream 100 bases:

>100_bases
GTAGCCTTGGCAGTCGAACGCCCCTGAGCGAATCACACGGCGCGGGGCAGACATACGCGCCCGGATCACCGGGCGTGACA
GAGGATGATCGGAAGGAATC

Downstream 100 bases:

>100_bases
TCCGACGCCCTTCTCGCCTGCCTCTCATCCGGCGTTGCGCCCTGCGCACGCCGGATTTGTTTGTTCGCCAGTTCGTTATC
GCGCCGTCTACATAAATGGA

Product: transcriptional regulator, putative

Products: NA

Alternate protein names: Copper efflux regulator; Copper export regulator [H]

Number of amino acids: Translated: 132; Mature: 131

Protein sequence:

>132_residues
MAKQTYSISDLANELDITTRAIRFYEEQGMLTPTRRGQERIYSPKDRVALKLILRGKRIGFSLAECKTLIELYDPKAGNQ
KQLNIMLQMIAERRQQLEQQLLDIQQMQLELDTAEERCRTALESTLAKQAAS

Sequences:

>Translated_132_residues
MAKQTYSISDLANELDITTRAIRFYEEQGMLTPTRRGQERIYSPKDRVALKLILRGKRIGFSLAECKTLIELYDPKAGNQ
KQLNIMLQMIAERRQQLEQQLLDIQQMQLELDTAEERCRTALESTLAKQAAS
>Mature_131_residues
AKQTYSISDLANELDITTRAIRFYEEQGMLTPTRRGQERIYSPKDRVALKLILRGKRIGFSLAECKTLIELYDPKAGNQK
QLNIMLQMIAERRQQLEQQLLDIQQMQLELDTAEERCRTALESTLAKQAAS

Specific function: Regulates the transcription of the copA and cueO genes. It detects cytoplasmic copper stress and activates transcription in response to increasing copper concentrations [H]

COG id: COG0789

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH merR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011789
- InterPro:   IPR009061
- InterPro:   IPR000551
- InterPro:   IPR015358 [H]

Pfam domain/function: PF00376 MerR; PF09278 MerR-DNA-bind [H]

EC number: NA

Molecular weight: Translated: 15233; Mature: 15102

Theoretical pI: Translated: 8.70; Mature: 8.70

Prosite motif: PS00552 HTH_MERR_1 ; PS50937 HTH_MERR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKQTYSISDLANELDITTRAIRFYEEQGMLTPTRRGQERIYSPKDRVALKLILRGKRIG
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHCCCCHHHHHHHHHHHCCCCC
FSLAECKTLIELYDPKAGNQKQLNIMLQMIAERRQQLEQQLLDIQQMQLELDTAEERCRT
CHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALESTLAKQAAS
HHHHHHHHHCCC
>Mature Secondary Structure 
AKQTYSISDLANELDITTRAIRFYEEQGMLTPTRRGQERIYSPKDRVALKLILRGKRIG
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHCCCCHHHHHHHHHHHCCCCC
FSLAECKTLIELYDPKAGNQKQLNIMLQMIAERRQQLEQQLLDIQQMQLELDTAEERCRT
CHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALESTLAKQAAS
HHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]