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The map label for this gene is atoS [H]

Identifier: 146283483

GI number: 146283483

Start: 3399055

End: 3401070

Strand: Direct

Name: atoS [H]

Synonym: PST_3156

Alternate gene names: 146283483

Gene position: 3399055-3401070 (Clockwise)

Preceding gene: 146283482

Following gene: 146283484

Centisome position: 74.42

GC content: 64.38

Gene sequence:

>2016_bases
ATGAAGCTGCGTCAGCGCCTCGAAAATCTCCCGGTCGGCCGCAAGCTGCTGCTCGCCCTGCTCGTCCTGCTCGCCGCCGT
GCTGCTGGTATCCAACCTCACCTTCATCAGTGCCGCCTACTGGATCTCGCGGCAGAGCGTCGCCCCGCAAGCCATGCACA
CGCTTGGCGAACTCTTCGCCACCGAGGAGCTGAGCAGCCGCGCCCTGTCCTCGCCCGAGGCAGCCAGCGAGTTGCTCAGG
CGCCTGGACGGCTATGCTCCGCTGCGCGCAGCAGTGATCTACGACCGCGACGGCAACAGCCTTGCGCAGCTGCAGCAGGG
TGAGCGGCTGCGGCTGCCGGAGCGGATCGACAAGGTCGCCGACTGGCGTGCTGGCGAAATCCGCGCCAACCTGCTGGTCA
GGCTACCGCAAGCGGACGGCAGCGCCGGGCATCTGCTGATGGTGGCCAGCAGCGAACTGCCAGGCGCGTTCTACACCGGC
ACGCTGACGGCGAGCCTGGCCATCCTGGTAGCCAGTCTGCTGCTCTGGATTCTGGTGGCGCGTCAGATCCGTCAGCTCAT
TACCCGGCCGATTCGCGATCTGGAGGCGCTGTCGCGCCAGGTCACCCGCGAGGAGGACTATTCCCTGCGCGCCAAGCCCG
GCAACCAGGACGAGATCGGTCGCCTCGCCGATGCCTTCAATACCATGCTGTCGCGCATGGAAGCCCGTGAGCAGCAGCTC
AAGCGCGCCCGTGACGACGCCCAGGAAGCCTTCGACCATGCCCAGGGTCTGGCCGAGGAAACGCGCCACTCCAACCGTAA
ACTGGAGCTGGAAGTGCAGGTGCGCAGCAAGATCGAACAGAAGCTCACCGGCTTCCAGAAATACCTCAATAGCATCATCG
ACTCGATGCCCTCGGCGCTGATCGCCCTCGACGAGCAGCTCTACGTCACCCAATGGAATCAGGAAGCCAGCGCCCTTTCC
GGCACGCCGCTGGACGATGCGCTGAATCAGCCGGTATTCGTCGCCTTCGAGCCGCTCAAGCCCTTCCTCGCGCAGATCCG
CCGCAGCTCCGAGCAGCATGTGGTGGAAAAGATCGAGAAAGTGACCTGGCTGCGCAACGACGAGCCACACCACTACGCGC
TCACCTGCTATCCACTGACCGGCGGCGGCGGTCGTGGCGTGGTGATCCGCATCGACGACATCACCCAGCGCATCAACATG
GAAGAAATGATGGTGCAGTCGGAGAAGATGCTCTCGGTGGGCAGCCTGGCGGCCGGCATGGCTCACGAGATCAACAACCC
CCTCGGCGCCATCCTGCACAACGCCCAGAACATACGTCGCCGGCTCTCCGCCGAGCTCGAGCGCAATCGCGAGGCGGCCG
AGGAAACCGGGGTGCGCCTGGAGGCAGTCAACCAGTACTTGCAGCGCCGCGAGGTGCCGCAGCTGCTCGATGGTATCCAG
CAGGCCGGCTCGAGGGCCGCGAAGATCGTCAGCCACATGCTCAGTTTCAGTCGCATGAGCAACCGCCAACTGGCCGACTG
CCATTTGCCGGTGCTGATCGACCAGGCCCTGGAGATCGCCGGAAACGACTTCGCCCTGATGGAAGGCTTCGACTTCAAGG
CCATCGATATCGTCCGTGACTTCGACCCGCGCGTGGATCGGGTGCCCTGCATCGGCAACGAGCTGGAGCAGGTGCTGCTC
AATCTGCTGAAGAACGCGGCCCAGGCCATCCATGCGCACCACAGCGGCGAGCCGGGGCAGATCATTCTGCGTACCCGGCT
GAACCCGCCTTGGGCGGAAATCCAGGTGGAGGACAACGGCGGCGGCATCCCCGAGAACGTGCGCAAGCGCATCTTCGAAC
CTTTCTTCACCACCAAGGAAGTCGGCCAGGGAACCGGACTGGGCCTTTCCGTTTCGTATTTCATCATCACCAACAATCAC
CAGGGTCAGATGGAGGTGCAGTGCCAACCCGGCCACGGCACCACCTTCACCCTGCGACTGCCGCTAAGCTCGCCCGTCGA
GCCGACTGCGACCTGA

Upstream 100 bases:

>100_bases
CTGCATGACCGTCTGCGCGAGTACCTCGGCCTGCGCGGATTGCCCACGGACTGAGCGACGGCTACCCTGCTGAAACCCTC
CGCCAAGCCGTGCCCGTTCC

Downstream 100 bases:

>100_bases
ACAAGGAAAAACCATGGGCAATCGACTATCCAAGATCTACACCCGCACCGGCGACAGCGGCGAAACCGGCCTGGGCGACG
GCCGTCGGGTCGCCAAGGAT

Product: sensory box histidine kinase/response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 671; Mature: 671

Protein sequence:

>671_residues
MKLRQRLENLPVGRKLLLALLVLLAAVLLVSNLTFISAAYWISRQSVAPQAMHTLGELFATEELSSRALSSPEAASELLR
RLDGYAPLRAAVIYDRDGNSLAQLQQGERLRLPERIDKVADWRAGEIRANLLVRLPQADGSAGHLLMVASSELPGAFYTG
TLTASLAILVASLLLWILVARQIRQLITRPIRDLEALSRQVTREEDYSLRAKPGNQDEIGRLADAFNTMLSRMEAREQQL
KRARDDAQEAFDHAQGLAEETRHSNRKLELEVQVRSKIEQKLTGFQKYLNSIIDSMPSALIALDEQLYVTQWNQEASALS
GTPLDDALNQPVFVAFEPLKPFLAQIRRSSEQHVVEKIEKVTWLRNDEPHHYALTCYPLTGGGGRGVVIRIDDITQRINM
EEMMVQSEKMLSVGSLAAGMAHEINNPLGAILHNAQNIRRRLSAELERNREAAEETGVRLEAVNQYLQRREVPQLLDGIQ
QAGSRAAKIVSHMLSFSRMSNRQLADCHLPVLIDQALEIAGNDFALMEGFDFKAIDIVRDFDPRVDRVPCIGNELEQVLL
NLLKNAAQAIHAHHSGEPGQIILRTRLNPPWAEIQVEDNGGGIPENVRKRIFEPFFTTKEVGQGTGLGLSVSYFIITNNH
QGQMEVQCQPGHGTTFTLRLPLSSPVEPTAT

Sequences:

>Translated_671_residues
MKLRQRLENLPVGRKLLLALLVLLAAVLLVSNLTFISAAYWISRQSVAPQAMHTLGELFATEELSSRALSSPEAASELLR
RLDGYAPLRAAVIYDRDGNSLAQLQQGERLRLPERIDKVADWRAGEIRANLLVRLPQADGSAGHLLMVASSELPGAFYTG
TLTASLAILVASLLLWILVARQIRQLITRPIRDLEALSRQVTREEDYSLRAKPGNQDEIGRLADAFNTMLSRMEAREQQL
KRARDDAQEAFDHAQGLAEETRHSNRKLELEVQVRSKIEQKLTGFQKYLNSIIDSMPSALIALDEQLYVTQWNQEASALS
GTPLDDALNQPVFVAFEPLKPFLAQIRRSSEQHVVEKIEKVTWLRNDEPHHYALTCYPLTGGGGRGVVIRIDDITQRINM
EEMMVQSEKMLSVGSLAAGMAHEINNPLGAILHNAQNIRRRLSAELERNREAAEETGVRLEAVNQYLQRREVPQLLDGIQ
QAGSRAAKIVSHMLSFSRMSNRQLADCHLPVLIDQALEIAGNDFALMEGFDFKAIDIVRDFDPRVDRVPCIGNELEQVLL
NLLKNAAQAIHAHHSGEPGQIILRTRLNPPWAEIQVEDNGGGIPENVRKRIFEPFFTTKEVGQGTGLGLSVSYFIITNNH
QGQMEVQCQPGHGTTFTLRLPLSSPVEPTAT
>Mature_671_residues
MKLRQRLENLPVGRKLLLALLVLLAAVLLVSNLTFISAAYWISRQSVAPQAMHTLGELFATEELSSRALSSPEAASELLR
RLDGYAPLRAAVIYDRDGNSLAQLQQGERLRLPERIDKVADWRAGEIRANLLVRLPQADGSAGHLLMVASSELPGAFYTG
TLTASLAILVASLLLWILVARQIRQLITRPIRDLEALSRQVTREEDYSLRAKPGNQDEIGRLADAFNTMLSRMEAREQQL
KRARDDAQEAFDHAQGLAEETRHSNRKLELEVQVRSKIEQKLTGFQKYLNSIIDSMPSALIALDEQLYVTQWNQEASALS
GTPLDDALNQPVFVAFEPLKPFLAQIRRSSEQHVVEKIEKVTWLRNDEPHHYALTCYPLTGGGGRGVVIRIDDITQRINM
EEMMVQSEKMLSVGSLAAGMAHEINNPLGAILHNAQNIRRRLSAELERNREAAEETGVRLEAVNQYLQRREVPQLLDGIQ
QAGSRAAKIVSHMLSFSRMSNRQLADCHLPVLIDQALEIAGNDFALMEGFDFKAIDIVRDFDPRVDRVPCIGNELEQVLL
NLLKNAAQAIHAHHSGEPGQIILRTRLNPPWAEIQVEDNGGGIPENVRKRIFEPFFTTKEVGQGTGLGLSVSYFIITNNH
QGQMEVQCQPGHGTTFTLRLPLSSPVEPTAT

Specific function: Member of the two-component regulatory system AtoS/AtoC; may activate AtoC by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=379, Percent_Identity=30.8707124010554, Blast_Score=143, Evalue=3e-35,
Organism=Escherichia coli, GI1790436, Length=265, Percent_Identity=32.4528301886792, Blast_Score=106, Evalue=4e-24,
Organism=Escherichia coli, GI1790300, Length=398, Percent_Identity=27.1356783919598, Blast_Score=105, Evalue=8e-24,
Organism=Escherichia coli, GI145693157, Length=308, Percent_Identity=25.974025974026, Blast_Score=81, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 74838; Mature: 74838

Theoretical pI: Translated: 6.42; Mature: 6.42

Prosite motif: PS50885 HAMP ; PS50112 PAS ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLRQRLENLPVGRKLLLALLVLLAAVLLVSNLTFISAAYWISRQSVAPQAMHTLGELFA
CCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
TEELSSRALSSPEAASELLRRLDGYAPLRAAVIYDRDGNSLAQLQQGERLRLPERIDKVA
HHHHHHHHCCCCHHHHHHHHHHCCCCCEEEEEEEECCCCHHHHHHCCCCCCCHHHHHHHH
DWRAGEIRANLLVRLPQADGSAGHLLMVASSELPGAFYTGTLTASLAILVASLLLWILVA
CCCCCCEEEEEEEEECCCCCCCCEEEEEECCCCCCCEEHHHHHHHHHHHHHHHHHHHHHH
RQIRQLITRPIRDLEALSRQVTREEDYSLRAKPGNQDEIGRLADAFNTMLSRMEAREQQL
HHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
KRARDDAQEAFDHAQGLAEETRHSNRKLELEVQVRSKIEQKLTGFQKYLNSIIDSMPSAL
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IALDEQLYVTQWNQEASALSGTPLDDALNQPVFVAFEPLKPFLAQIRRSSEQHVVEKIEK
HHHCCHHEEEECCCHHHHCCCCCCHHHHCCCEEEEECCHHHHHHHHHCCHHHHHHHHHHH
VTWLRNDEPHHYALTCYPLTGGGGRGVVIRIDDITQRINMEEMMVQSEKMLSVGSLAAGM
HHHCCCCCCCEEEEEEEEEECCCCCEEEEEEHHHHHHHCHHHHHHHHHHHHHHHHHHHHH
AHEINNPLGAILHNAQNIRRRLSAELERNREAAEETGVRLEAVNQYLQRREVPQLLDGIQ
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHH
QAGSRAAKIVSHMLSFSRMSNRQLADCHLPVLIDQALEIAGNDFALMEGFDFKAIDIVRD
HHHHHHHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHCCCCEEEECCCCCHHHHHHHC
FDPRVDRVPCIGNELEQVLLNLLKNAAQAIHAHHSGEPGQIILRTRLNPPWAEIQVEDNG
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCEEEEEECCC
GGIPENVRKRIFEPFFTTKEVGQGTGLGLSVSYFIITNNHQGQMEVQCQPGHGTTFTLRL
CCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEECCCCCEEEEEEECCCCCEEEEEC
PLSSPVEPTAT
CCCCCCCCCCC
>Mature Secondary Structure
MKLRQRLENLPVGRKLLLALLVLLAAVLLVSNLTFISAAYWISRQSVAPQAMHTLGELFA
CCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
TEELSSRALSSPEAASELLRRLDGYAPLRAAVIYDRDGNSLAQLQQGERLRLPERIDKVA
HHHHHHHHCCCCHHHHHHHHHHCCCCCEEEEEEEECCCCHHHHHHCCCCCCCHHHHHHHH
DWRAGEIRANLLVRLPQADGSAGHLLMVASSELPGAFYTGTLTASLAILVASLLLWILVA
CCCCCCEEEEEEEEECCCCCCCCEEEEEECCCCCCCEEHHHHHHHHHHHHHHHHHHHHHH
RQIRQLITRPIRDLEALSRQVTREEDYSLRAKPGNQDEIGRLADAFNTMLSRMEAREQQL
HHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
KRARDDAQEAFDHAQGLAEETRHSNRKLELEVQVRSKIEQKLTGFQKYLNSIIDSMPSAL
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IALDEQLYVTQWNQEASALSGTPLDDALNQPVFVAFEPLKPFLAQIRRSSEQHVVEKIEK
HHHCCHHEEEECCCHHHHCCCCCCHHHHCCCEEEEECCHHHHHHHHHCCHHHHHHHHHHH
VTWLRNDEPHHYALTCYPLTGGGGRGVVIRIDDITQRINMEEMMVQSEKMLSVGSLAAGM
HHHCCCCCCCEEEEEEEEEECCCCCEEEEEEHHHHHHHCHHHHHHHHHHHHHHHHHHHHH
AHEINNPLGAILHNAQNIRRRLSAELERNREAAEETGVRLEAVNQYLQRREVPQLLDGIQ
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHH
QAGSRAAKIVSHMLSFSRMSNRQLADCHLPVLIDQALEIAGNDFALMEGFDFKAIDIVRD
HHHHHHHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHCCCCEEEECCCCCHHHHHHHC
FDPRVDRVPCIGNELEQVLLNLLKNAAQAIHAHHSGEPGQIILRTRLNPPWAEIQVEDNG
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCEEEEEECCC
GGIPENVRKRIFEPFFTTKEVGQGTGLGLSVSYFIITNNHQGQMEVQCQPGHGTTFTLRL
CCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEECCCCCEEEEEEECCCCCEEEEEC
PLSSPVEPTAT
CCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8346225; 9097040; 9278503 [H]