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The map label for this gene is uppP2

Identifier: 146283310

GI number: 146283310

Start: 3209451

End: 3210263

Strand: Direct

Name: uppP2

Synonym: PST_2975

Alternate gene names: 146283310

Gene position: 3209451-3210263 (Clockwise)

Preceding gene: 146283304

Following gene: 146283311

Centisome position: 70.27

GC content: 64.08

Gene sequence:

>813_bases
ATGGATTTAATTCAGATCATCGTCCTGGCCATCGTGCAGGGGCTTACCGAGTTCTTGCCGGTATCGAGCTCCGCTCACCT
GATCCTCTTCCCGCACCTGGTGGGCTGGGACGACCAGGGGCTGGCATTCGACGTAGCCGTGCACCTGGGCACGCTCGCCG
CCGTGGTCTGGTACTTCCGCCAGGAAGTGTTCGGCATGACCCGCGACTGGTTCGCATCCCTTGCCCGCCGCGAGCGTGTC
GGTGACAGCCGGCTGGCCTGGGCCGTCATTCTCGGCACGATCCCGGCGGGCATCGCCGGGCTGCTGTTCAAGGGATTCAT
CGAGGAGCAGATGCGTTCGCCGCTGGTGATCGCCTGGGCAACCATCGGCTTCGGCCTGCTGCTGTGGTGGTCCGACGTGG
TCAGCCGGCGTACCCCGCAACCGCGCGATGAGCACAGCCTGAGCTGGAAAGACATTCTGCTGATCGGCTGTGCTCAGGCA
CTGGCACTGATTCCCGGCACCTCGCGCTCAGGCGTCACCATGACGGCTGGCCTGCTGCTGGGACTGTCGCGCTCCGGCGC
GGCGCGCTTCTCGTTTTTGCTGTCGATCCCGATCATCGTGCTTGCCAGCGGCTTGAGCACGCTCGATCTGGTGGAAGGCG
AGGTAGCCGTGGACTGGACGGCAATGGGGCTGGGGGTGGTGCTGTCGGCGATCAGCGCCTACCTGTGCATCCACTTTTTC
CTCAAACTGCTGGAGCGTGTCGGCATGTTGCCGTTCGTGATCTATCGCCTGATTCTCGGCGCCGTGCTGCTGGTACTGTT
CAGCGGCGTCTGA

Upstream 100 bases:

>100_bases
CAAGCGCCTCTGAAGGAGGCCCCGAGGCATCGCCTCGCGCAGACCATCCGCTCATCGCACGTGCTCGTCGTGCATCAGAA
GACATCGCAGGAAACACGCA

Downstream 100 bases:

>100_bases
GTGATCACGCCGCGGCTCGCGCTGAGCGCTTGCCGCGGCGTTTGGCCGGATCGTCTTGCGACGCCCTAGCCTTGTGGCAG
ATCGATCAGCAGCGGGCCGA

Product: undecaprenyl pyrophosphate phosphatase

Products: NA

Alternate protein names: Bacitracin resistance protein 2; Undecaprenyl pyrophosphate phosphatase 2

Number of amino acids: Translated: 270; Mature: 270

Protein sequence:

>270_residues
MDLIQIIVLAIVQGLTEFLPVSSSAHLILFPHLVGWDDQGLAFDVAVHLGTLAAVVWYFRQEVFGMTRDWFASLARRERV
GDSRLAWAVILGTIPAGIAGLLFKGFIEEQMRSPLVIAWATIGFGLLLWWSDVVSRRTPQPRDEHSLSWKDILLIGCAQA
LALIPGTSRSGVTMTAGLLLGLSRSGAARFSFLLSIPIIVLASGLSTLDLVEGEVAVDWTAMGLGVVLSAISAYLCIHFF
LKLLERVGMLPFVIYRLILGAVLLVLFSGV

Sequences:

>Translated_270_residues
MDLIQIIVLAIVQGLTEFLPVSSSAHLILFPHLVGWDDQGLAFDVAVHLGTLAAVVWYFRQEVFGMTRDWFASLARRERV
GDSRLAWAVILGTIPAGIAGLLFKGFIEEQMRSPLVIAWATIGFGLLLWWSDVVSRRTPQPRDEHSLSWKDILLIGCAQA
LALIPGTSRSGVTMTAGLLLGLSRSGAARFSFLLSIPIIVLASGLSTLDLVEGEVAVDWTAMGLGVVLSAISAYLCIHFF
LKLLERVGMLPFVIYRLILGAVLLVLFSGV
>Mature_270_residues
MDLIQIIVLAIVQGLTEFLPVSSSAHLILFPHLVGWDDQGLAFDVAVHLGTLAAVVWYFRQEVFGMTRDWFASLARRERV
GDSRLAWAVILGTIPAGIAGLLFKGFIEEQMRSPLVIAWATIGFGLLLWWSDVVSRRTPQPRDEHSLSWKDILLIGCAQA
LALIPGTSRSGVTMTAGLLLGLSRSGAARFSFLLSIPIIVLASGLSTLDLVEGEVAVDWTAMGLGVVLSAISAYLCIHFF
LKLLERVGMLPFVIYRLILGAVLLVLFSGV

Specific function: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin

COG id: COG1968

COG function: function code V; Uncharacterized bacitracin resistance protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uppP family

Homologues:

Organism=Escherichia coli, GI1789437, Length=265, Percent_Identity=36.2264150943396, Blast_Score=162, Evalue=2e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UPPP2_PSEU5 (A4VNS0)

Other databases:

- EMBL:   CP000304
- RefSeq:   YP_001173463.1
- STRING:   A4VNS0
- GeneID:   5095937
- GenomeReviews:   CP000304_GR
- KEGG:   psa:PST_2975
- eggNOG:   COG1968
- HOGENOM:   HBG391969
- OMA:   SAYICVK
- PhylomeDB:   A4VNS0
- ProtClustDB:   PRK00281
- BioCyc:   PSTU379731:PST_2975-MONOMER
- GO:   GO:0016311
- HAMAP:   MF_01006
- InterPro:   IPR003824
- TIGRFAMs:   TIGR00753

Pfam domain/function: PF02673 BacA

EC number: =3.6.1.27

Molecular weight: Translated: 29371; Mature: 29371

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1e737404)-; HASH(0x1ec10de8)-; HASH(0x1e116514)-; HASH(0x1e19db90)-; HASH(0x1ec22400)-; HASH(0x1ea1c954)-; HASH(0x1ec2240c)-; HASH(0x1ec38784)-;

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLIQIIVLAIVQGLTEFLPVSSSAHLILFPHLVGWDDQGLAFDVAVHLGTLAAVVWYFR
CHHHHHHHHHHHHHHHHHCCCCCCCCEEEECHHCCCCCCCCHHHHHHHHHHHHHHHHHHH
QEVFGMTRDWFASLARRERVGDSRLAWAVILGTIPAGIAGLLFKGFIEEQMRSPLVIAWA
HHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHH
TIGFGLLLWWSDVVSRRTPQPRDEHSLSWKDILLIGCAQALALIPGTSRSGVTMTAGLLL
HHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
GLSRSGAARFSFLLSIPIIVLASGLSTLDLVEGEVAVDWTAMGLGVVLSAISAYLCIHFF
HCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHH
LKLLERVGMLPFVIYRLILGAVLLVLFSGV
HHHHHHHCHHHHHHHHHHHHHHHHHHHCCH
>Mature Secondary Structure
MDLIQIIVLAIVQGLTEFLPVSSSAHLILFPHLVGWDDQGLAFDVAVHLGTLAAVVWYFR
CHHHHHHHHHHHHHHHHHCCCCCCCCEEEECHHCCCCCCCCHHHHHHHHHHHHHHHHHHH
QEVFGMTRDWFASLARRERVGDSRLAWAVILGTIPAGIAGLLFKGFIEEQMRSPLVIAWA
HHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHH
TIGFGLLLWWSDVVSRRTPQPRDEHSLSWKDILLIGCAQALALIPGTSRSGVTMTAGLLL
HHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
GLSRSGAARFSFLLSIPIIVLASGLSTLDLVEGEVAVDWTAMGLGVVLSAISAYLCIHFF
HCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHH
LKLLERVGMLPFVIYRLILGAVLLVLFSGV
HHHHHHHCHHHHHHHHHHHHHHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA