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The map label for this gene is pcbC [H]

Identifier: 146283232

GI number: 146283232

Start: 3119660

End: 3120640

Strand: Direct

Name: pcbC [H]

Synonym: PST_2897

Alternate gene names: 146283232

Gene position: 3119660-3120640 (Clockwise)

Preceding gene: 146283231

Following gene: 146283233

Centisome position: 68.3

GC content: 66.87

Gene sequence:

>981_bases
ATGAACGAATCCCTTTGCGCCCGCCATCTCGAAGCCGCCGCGCTGCCGCTGATCGACATCGCCGGGCTGTTTTCTCCCGA
TCTCGACGAGCGCGCCGCCGTGGCCGAACGCATCGGTGCGGCCTGTCGCGAGGTCGGTTTCTTCTGTATCGCCAACCACG
GCGTCGACGCGGCGCTGCAGCAGGCGGTGTTCGAGCAGGCGCGGGCCTTCTTCGCCCTGCCGGAACCCGGCAAGCGCGCA
CTGGACAAGCTGTTCTCGAAGGCCAATCGCGGCTATGAGCCGTTGCGCGGGCAGGTGCTGGAAGCCGGTGCGCCGGCCGA
TCTCAAGGAAGGCTTCTACATCGGCGAGGAGCTGGCCGAGGACGACCCGCGGGTACTGGCCGGGCGTTTCAACCACGGTG
CCAACCAGTGGCCGAGCGAGCTCGCGGAGTTTCGCCCGACCATGGAGCGCTATCGCGACGCGATGAATGCGCTGGCGAAT
CGGCTGATGGGGGCCATCGCGCTGTCGCTGCAACTGCCGGAGGAACATTTCGCCGGCTTCTGCCGCGACTCCATGAGCAC
CCTGCGCCTGCTGCATTACCCGCCGCAGCCGGCCAATTCCGCGCCCGGCGAAAAGGGCTGTGGCGCGCATACCGATTTCG
GAGGGCTGACGCTGCTTCTGCAGGACGAGAATCCCGGCCTGCAGGTCTGGGATCGTCACAGCAAGAGCTGGATTCACGCG
GCCCCTGTGCCCGGCACCTATGTGGTCAATCTGGGCGACATGATCGCCCGCTGGACCAACGACCAGTACCGTTCGACGCT
GCACCGGGTGGTCAACATGTCCGGACGCGAGCGCTACAGCGTGCCGTTCTTCTTCAGCGGCAACCCGGACCACGTGGTCG
AGTGCCTGCCGACCTGCCTCGCGCCCGGCGAGGCGCCGCGCTACCCCGCGGTGACGGTGGAAGAACACCACCGCGAGATG
TACCGGAGGACCTATGGCTGA

Upstream 100 bases:

>100_bases
CATCGGCGTGCTCGATATTCTCTGCTTTTGAGTACAAGCGGCGCGCCGGATACTGCGCTCGCCGGTCGCCATTCCGCGGT
CGGCAGAGCAGGATCGAGCC

Downstream 100 bases:

>100_bases
CATCGTCCTCATCCACGGGGCCTGGGCCGGTAGCTGGGTCTGGGATTCGCTGCAGGATGGCCTGCGCGATGCCGGCCACC
GACCGCATGCGGTCGATCTG

Product: oxidoreductase

Products: NA

Alternate protein names: IPNS [H]

Number of amino acids: Translated: 326; Mature: 326

Protein sequence:

>326_residues
MNESLCARHLEAAALPLIDIAGLFSPDLDERAAVAERIGAACREVGFFCIANHGVDAALQQAVFEQARAFFALPEPGKRA
LDKLFSKANRGYEPLRGQVLEAGAPADLKEGFYIGEELAEDDPRVLAGRFNHGANQWPSELAEFRPTMERYRDAMNALAN
RLMGAIALSLQLPEEHFAGFCRDSMSTLRLLHYPPQPANSAPGEKGCGAHTDFGGLTLLLQDENPGLQVWDRHSKSWIHA
APVPGTYVVNLGDMIARWTNDQYRSTLHRVVNMSGRERYSVPFFFSGNPDHVVECLPTCLAPGEAPRYPAVTVEEHHREM
YRRTYG

Sequences:

>Translated_326_residues
MNESLCARHLEAAALPLIDIAGLFSPDLDERAAVAERIGAACREVGFFCIANHGVDAALQQAVFEQARAFFALPEPGKRA
LDKLFSKANRGYEPLRGQVLEAGAPADLKEGFYIGEELAEDDPRVLAGRFNHGANQWPSELAEFRPTMERYRDAMNALAN
RLMGAIALSLQLPEEHFAGFCRDSMSTLRLLHYPPQPANSAPGEKGCGAHTDFGGLTLLLQDENPGLQVWDRHSKSWIHA
APVPGTYVVNLGDMIARWTNDQYRSTLHRVVNMSGRERYSVPFFFSGNPDHVVECLPTCLAPGEAPRYPAVTVEEHHREM
YRRTYG
>Mature_326_residues
MNESLCARHLEAAALPLIDIAGLFSPDLDERAAVAERIGAACREVGFFCIANHGVDAALQQAVFEQARAFFALPEPGKRA
LDKLFSKANRGYEPLRGQVLEAGAPADLKEGFYIGEELAEDDPRVLAGRFNHGANQWPSELAEFRPTMERYRDAMNALAN
RLMGAIALSLQLPEEHFAGFCRDSMSTLRLLHYPPQPANSAPGEKGCGAHTDFGGLTLLLQDENPGLQVWDRHSKSWIHA
APVPGTYVVNLGDMIARWTNDQYRSTLHRVVNMSGRERYSVPFFFSGNPDHVVECLPTCLAPGEAPRYPAVTVEEHHREM
YRRTYG

Specific function: Removes, in the presence of oxygen, 4 hydrogen atoms from delta-L-(alpha-aminoadipyl)-L-cysteinyl-D-valine (ACV) to form the azetidinone and thiazolidine rings of isopenicillin [H]

COG id: COG3491

COG function: function code R; Isopenicillin N synthase and related dioxygenases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Fe2OG dioxygenase domain [H]

Homologues:

Organism=Drosophila melanogaster, GI28572124, Length=343, Percent_Identity=27.4052478134111, Blast_Score=96, Evalue=5e-20,
Organism=Drosophila melanogaster, GI85816264, Length=289, Percent_Identity=27.681660899654, Blast_Score=88, Evalue=7e-18,
Organism=Drosophila melanogaster, GI24649039, Length=359, Percent_Identity=23.9554317548747, Blast_Score=81, Evalue=8e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002057
- InterPro:   IPR002283
- InterPro:   IPR005123 [H]

Pfam domain/function: PF03171 2OG-FeII_Oxy [H]

EC number: =1.21.3.1 [H]

Molecular weight: Translated: 36146; Mature: 36146

Theoretical pI: Translated: 5.92; Mature: 5.92

Prosite motif: PS00290 IG_MHC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNESLCARHLEAAALPLIDIAGLFSPDLDERAAVAERIGAACREVGFFCIANHGVDAALQ
CCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCEEECCCHHHHHH
QAVFEQARAFFALPEPGKRALDKLFSKANRGYEPLRGQVLEAGAPADLKEGFYIGEELAE
HHHHHHHHHEECCCCCHHHHHHHHHHHHCCCCCCCCCHHCCCCCCCHHHCCCCHHHHHCC
DDPRVLAGRFNHGANQWPSELAEFRPTMERYRDAMNALANRLMGAIALSLQLPEEHFAGF
CCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCHHHHHHH
CRDSMSTLRLLHYPPQPANSAPGEKGCGAHTDFGGLTLLLQDENPGLQVWDRHSKSWIHA
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCEEECCCCCEEEE
APVPGTYVVNLGDMIARWTNDQYRSTLHRVVNMSGRERYSVPFFFSGNPDHVVECLPTCL
CCCCCEEEEEHHHHHHHHCCHHHHHHHHHHHCCCCCCEECCCEEECCCHHHHHHHHHHHC
APGEAPRYPAVTVEEHHREMYRRTYG
CCCCCCCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MNESLCARHLEAAALPLIDIAGLFSPDLDERAAVAERIGAACREVGFFCIANHGVDAALQ
CCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCEEECCCHHHHHH
QAVFEQARAFFALPEPGKRALDKLFSKANRGYEPLRGQVLEAGAPADLKEGFYIGEELAE
HHHHHHHHHEECCCCCHHHHHHHHHHHHCCCCCCCCCHHCCCCCCCHHHCCCCHHHHHCC
DDPRVLAGRFNHGANQWPSELAEFRPTMERYRDAMNALANRLMGAIALSLQLPEEHFAGF
CCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCHHHHHHH
CRDSMSTLRLLHYPPQPANSAPGEKGCGAHTDFGGLTLLLQDENPGLQVWDRHSKSWIHA
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCEEECCCCCEEEE
APVPGTYVVNLGDMIARWTNDQYRSTLHRVVNMSGRERYSVPFFFSGNPDHVVECLPTCL
CCCCCEEEEEHHHHHHHHCCHHHHHHHHHHHCCCCCCEECCCEEECCCHHHHHHHHHHHC
APGEAPRYPAVTVEEHHREMYRRTYG
CCCCCCCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1956290 [H]