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The map label for this gene is dapL [H]

Identifier: 146283169

GI number: 146283169

Start: 3055014

End: 3056210

Strand: Direct

Name: dapL [H]

Synonym: PST_2834

Alternate gene names: 146283169

Gene position: 3055014-3056210 (Clockwise)

Preceding gene: 146283168

Following gene: 146283172

Centisome position: 66.89

GC content: 63.99

Gene sequence:

>1197_bases
ATGAACAACGCCCTGAATCTGCTGCATCCCTACCCGTTCGAGAAACTGCGCACGCTGCTTGCCGGCGTCCAACCGCCTGC
GGACAAGCGCGCCATCGCCCTGTCGATCGGCGAACCCAAGCATCGTTCGCCGGATTTCGTCGCCCAGGCGCTGGCGGACA
ACCTCGACCAACTCTCGGTCTATCCGACCACGCTCGGCATTCCTGCGCTGCGCGAAGCCATCGCGCGCTGGTGCGAGGGG
CGTTTCGGCCTGGCTGCCGAGGCGCTGGACCCGGCGCGCCATGTCTTGCCGGTGAACGGGACACGCGAAGCACTGTTCGC
CTTCACCCAGGCTGTGGTCGATCGCAACGCCAATGGGTTGGTGGTCAGCCCCAATCCGTTCTATCAGATCTACGAAGGCG
CAGCGCTGCTCGCCGGAGCCACGCCGCACTACCTGCCATGCCTCGAAGAGAACGGCTTCAACCCGGATTTCGACGCCGTG
CCCGCGGAGATCTGGCAGCGCTGCCAGATCCTCTTCCTCTGCTCGCCAGGCAACCCGACCGGTGCGCTGGTACCGCTGGA
AACACTGCAGAAGCTGATCGCCCTGGCCGACGAGCACGACTTCGTCATCGCCGCCGACGAGTGTTACAGCGAGCTGTACT
TCGACGAGGCCAATCCCCCTGCAGGCTTGCTCAGCGCCTGTGCTGCACTGGGCCGCAACGACTACAAGCGCTGCGTGGTG
TTTCATAGCCTGTCGAAGCGCTCGAACCTGCCGGGCCTGCGCTCGGGCTTTGTCGCCGGTGATGCCGAAATCCTCAAGGC
ATTCCTGCTCTACCGTACCTATCACGGTTGCGCCATGCCGGTGCAGACCCAGCTGGCGAGCATCGCCGCCTGGAACGACG
AGATACATGTGCGCGCCAATCGCGAGCTGTATCGAGCCAAATTCGACGCGGTGCTGGACATCCTCGCGCCGGAGATGGAC
GTACAGCGCCCGGATGGTGGCTTCTATCTCTGGCCGAAAACGCCGATGGATGACCAGCAATTCACCCGTGAGCTCTTCGC
CCGCGAGCACGTCACCGTGGTGCCCGGGTCGTACCTGTCACGCGAGGTGGATGGTGCCTCTCCGGGTGCCGGACGCGTGC
GCATGGCGCTGGTCGCACCGCTAGCTGAATGCATCGAAGCAGCACAGCGAATTCGCCACTTCATCGAAACGCTCTGA

Upstream 100 bases:

>100_bases
GCCAGACCCTGCGCGGCTGCGCTTACTATGGCGGCGGACGCGACGACTGAAACAACGAATGCGGGGCGGTCGCCGCGCTC
ATCCTGAAAGAACAGCACTC

Downstream 100 bases:

>100_bases
CAGCGCACCGGGCGGTCCGACCGCCCGGCCTGACGATCCGTCAAGCCACGCCAGGCGGGATCATGTCCTTGCCGTAGTCG
CGCAGCTTCTCCAGGTTCTC

Product: succinyldiaminopimelate transaminase

Products: NA

Alternate protein names: DAP-AT; DAP-aminotransferase; LL-DAP-aminotransferase [H]

Number of amino acids: Translated: 398; Mature: 398

Protein sequence:

>398_residues
MNNALNLLHPYPFEKLRTLLAGVQPPADKRAIALSIGEPKHRSPDFVAQALADNLDQLSVYPTTLGIPALREAIARWCEG
RFGLAAEALDPARHVLPVNGTREALFAFTQAVVDRNANGLVVSPNPFYQIYEGAALLAGATPHYLPCLEENGFNPDFDAV
PAEIWQRCQILFLCSPGNPTGALVPLETLQKLIALADEHDFVIAADECYSELYFDEANPPAGLLSACAALGRNDYKRCVV
FHSLSKRSNLPGLRSGFVAGDAEILKAFLLYRTYHGCAMPVQTQLASIAAWNDEIHVRANRELYRAKFDAVLDILAPEMD
VQRPDGGFYLWPKTPMDDQQFTRELFAREHVTVVPGSYLSREVDGASPGAGRVRMALVAPLAECIEAAQRIRHFIETL

Sequences:

>Translated_398_residues
MNNALNLLHPYPFEKLRTLLAGVQPPADKRAIALSIGEPKHRSPDFVAQALADNLDQLSVYPTTLGIPALREAIARWCEG
RFGLAAEALDPARHVLPVNGTREALFAFTQAVVDRNANGLVVSPNPFYQIYEGAALLAGATPHYLPCLEENGFNPDFDAV
PAEIWQRCQILFLCSPGNPTGALVPLETLQKLIALADEHDFVIAADECYSELYFDEANPPAGLLSACAALGRNDYKRCVV
FHSLSKRSNLPGLRSGFVAGDAEILKAFLLYRTYHGCAMPVQTQLASIAAWNDEIHVRANRELYRAKFDAVLDILAPEMD
VQRPDGGFYLWPKTPMDDQQFTRELFAREHVTVVPGSYLSREVDGASPGAGRVRMALVAPLAECIEAAQRIRHFIETL
>Mature_398_residues
MNNALNLLHPYPFEKLRTLLAGVQPPADKRAIALSIGEPKHRSPDFVAQALADNLDQLSVYPTTLGIPALREAIARWCEG
RFGLAAEALDPARHVLPVNGTREALFAFTQAVVDRNANGLVVSPNPFYQIYEGAALLAGATPHYLPCLEENGFNPDFDAV
PAEIWQRCQILFLCSPGNPTGALVPLETLQKLIALADEHDFVIAADECYSELYFDEANPPAGLLSACAALGRNDYKRCVV
FHSLSKRSNLPGLRSGFVAGDAEILKAFLLYRTYHGCAMPVQTQLASIAAWNDEIHVRANRELYRAKFDAVLDILAPEMD
VQRPDGGFYLWPKTPMDDQQFTRELFAREHVTVVPGSYLSREVDGASPGAGRVRMALVAPLAECIEAAQRIRHFIETL

Specific function: Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate, a reaction that requires three enzymes in E.coli

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=289, Percent_Identity=26.9896193771626, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI169881279, Length=289, Percent_Identity=26.9896193771626, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI56713256, Length=333, Percent_Identity=24.9249249249249, Blast_Score=83, Evalue=5e-16,
Organism=Homo sapiens, GI56713254, Length=333, Percent_Identity=24.9249249249249, Blast_Score=82, Evalue=8e-16,
Organism=Homo sapiens, GI4507369, Length=411, Percent_Identity=24.8175182481752, Blast_Score=80, Evalue=5e-15,
Organism=Escherichia coli, GI1788722, Length=407, Percent_Identity=29.2383292383292, Blast_Score=139, Evalue=3e-34,
Organism=Escherichia coli, GI1788627, Length=350, Percent_Identity=25.4285714285714, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1786816, Length=375, Percent_Identity=24.8, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1790797, Length=397, Percent_Identity=24.1813602015113, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17567663, Length=399, Percent_Identity=25.31328320802, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI71994476, Length=405, Percent_Identity=22.7160493827161, Blast_Score=73, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71994472, Length=405, Percent_Identity=22.7160493827161, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17567369, Length=272, Percent_Identity=23.1617647058824, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI28573069, Length=278, Percent_Identity=23.021582733813, Blast_Score=75, Evalue=8e-14,
Organism=Drosophila melanogaster, GI24646114, Length=278, Percent_Identity=23.021582733813, Blast_Score=75, Evalue=8e-14,
Organism=Drosophila melanogaster, GI28573067, Length=278, Percent_Identity=23.021582733813, Blast_Score=75, Evalue=8e-14,
Organism=Drosophila melanogaster, GI28573065, Length=278, Percent_Identity=23.021582733813, Blast_Score=75, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR019881
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.83 [H]

Molecular weight: Translated: 43793; Mature: 43793

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNALNLLHPYPFEKLRTLLAGVQPPADKRAIALSIGEPKHRSPDFVAQALADNLDQLSV
CCCCCCCCCCCCHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHCCHHHEEE
YPTTLGIPALREAIARWCEGRFGLAAEALDPARHVLPVNGTREALFAFTQAVVDRNANGL
CCHHCCCHHHHHHHHHHHCCCCCCHHHHCCCHHHEECCCCCHHHHHHHHHHHHCCCCCEE
VVSPNPFYQIYEGAALLAGATPHYLPCLEENGFNPDFDAVPAEIWQRCQILFLCSPGNPT
EECCCCCCHHHCCCEEEECCCCCCCCCHHCCCCCCCCCCCHHHHHCCCEEEEEECCCCCC
GALVPLETLQKLIALADEHDFVIAADECYSELYFDEANPPAGLLSACAALGRNDYKRCVV
CCEECHHHHHHHHHHCCCCCEEEEHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCHHHHHH
FHSLSKRSNLPGLRSGFVAGDAEILKAFLLYRTYHGCAMPVQTQLASIAAWNDEIHVRAN
HHHHHHHCCCCCHHCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCEEEEEC
RELYRAKFDAVLDILAPEMDVQRPDGGFYLWPKTPMDDQQFTRELFAREHVTVVPGSYLS
HHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCCHHHHHHHHHHCCCEEECCCHHHH
REVDGASPGAGRVRMALVAPLAECIEAAQRIRHFIETL
HCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNNALNLLHPYPFEKLRTLLAGVQPPADKRAIALSIGEPKHRSPDFVAQALADNLDQLSV
CCCCCCCCCCCCHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHCCHHHEEE
YPTTLGIPALREAIARWCEGRFGLAAEALDPARHVLPVNGTREALFAFTQAVVDRNANGL
CCHHCCCHHHHHHHHHHHCCCCCCHHHHCCCHHHEECCCCCHHHHHHHHHHHHCCCCCEE
VVSPNPFYQIYEGAALLAGATPHYLPCLEENGFNPDFDAVPAEIWQRCQILFLCSPGNPT
EECCCCCCHHHCCCEEEECCCCCCCCCHHCCCCCCCCCCCHHHHHCCCEEEEEECCCCCC
GALVPLETLQKLIALADEHDFVIAADECYSELYFDEANPPAGLLSACAALGRNDYKRCVV
CCEECHHHHHHHHHHCCCCCEEEEHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCHHHHHH
FHSLSKRSNLPGLRSGFVAGDAEILKAFLLYRTYHGCAMPVQTQLASIAAWNDEIHVRAN
HHHHHHHCCCCCHHCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCEEEEEC
RELYRAKFDAVLDILAPEMDVQRPDGGFYLWPKTPMDDQQFTRELFAREHVTVVPGSYLS
HHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCCHHHHHHHHHHCCCEEECCCHHHH
REVDGASPGAGRVRMALVAPLAECIEAAQRIRHFIETL
HCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA