Click here to switch to the map view.

The map label for this gene is fbp [H]

Identifier: 146283062

GI number: 146283062

Start: 2944848

End: 2945039

Strand: Direct

Name: fbp [H]

Synonym: PST_2723

Alternate gene names: 146283062

Gene position: 2944848-2945039 (Clockwise)

Preceding gene: 146283059

Following gene: 146283069

Centisome position: 64.48

GC content: 60.94

Gene sequence:

>192_bases
GTGATAGGCACCGGACGCGTGATCAAGGGCTGGGATATCGGCCTGATGGGAATGAAAGTCGGCGGTAAGCGCAGGCTCTT
CGTGCCGGCTCATCTGGGCTATGGCGAGCGGCAGATCGGCGCGCACATTCCGCCGAATTCGGATCTTCACTTCGAGATCG
AGCTGCTCGAAGTGCTGACCCGGGACGACTGA

Upstream 100 bases:

>100_bases
GGTCGTAAAAGGCGCGCTCATCACGACGCAATACCGCGGCACGCTGAGCGACGGCACGGAGTTCGACAGCTCCTACACGC
GCGGCAAGCCGTTCCAGTGC

Downstream 100 bases:

>100_bases
TCAGCAGCGCCATGCGGCTTGCGCACCGCATGGCGCTGCGATTTCAGCTCGCGCTGGTCGGCGCCTGGTGAGGAACGCCT
TGGGGGTACTCATCCCGATA

Product: hypothetical protein

Products: NA

Alternate protein names: Peptidyl-prolyl cis-trans isomerase; PPIase; Rotamase [H]

Number of amino acids: Translated: 63; Mature: 63

Protein sequence:

>63_residues
MIGTGRVIKGWDIGLMGMKVGGKRRLFVPAHLGYGERQIGAHIPPNSDLHFEIELLEVLTRDD

Sequences:

>Translated_63_residues
MIGTGRVIKGWDIGLMGMKVGGKRRLFVPAHLGYGERQIGAHIPPNSDLHFEIELLEVLTRDD
>Mature_63_residues
MIGTGRVIKGWDIGLMGMKVGGKRRLFVPAHLGYGERQIGAHIPPNSDLHFEIELLEVLTRDD

Specific function: PPIases accelerate the folding of proteins [H]

COG id: COG0545

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerases 1

Gene ontology:

Cell location: Cytoplasm And Periplasmic Protein [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Homo sapiens, GI206725530, Length=62, Percent_Identity=53.2258064516129, Blast_Score=69, Evalue=1e-12,
Organism=Homo sapiens, GI17149844, Length=62, Percent_Identity=53.2258064516129, Blast_Score=69, Evalue=1e-12,
Organism=Homo sapiens, GI17149842, Length=62, Percent_Identity=53.2258064516129, Blast_Score=69, Evalue=1e-12,
Organism=Homo sapiens, GI192448443, Length=63, Percent_Identity=49.2063492063492, Blast_Score=66, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17540882, Length=57, Percent_Identity=54.3859649122807, Blast_Score=65, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI71993519, Length=57, Percent_Identity=54.3859649122807, Blast_Score=62, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6320727, Length=57, Percent_Identity=56.140350877193, Blast_Score=72, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6323482, Length=57, Percent_Identity=49.1228070175439, Blast_Score=64, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6324194, Length=57, Percent_Identity=52.6315789473684, Blast_Score=63, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6323566, Length=57, Percent_Identity=50.8771929824561, Blast_Score=63, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24647110, Length=57, Percent_Identity=56.140350877193, Blast_Score=69, Evalue=5e-13,
Organism=Drosophila melanogaster, GI281363946, Length=57, Percent_Identity=50.8771929824561, Blast_Score=69, Evalue=6e-13,
Organism=Drosophila melanogaster, GI17352457, Length=57, Percent_Identity=50.8771929824561, Blast_Score=69, Evalue=6e-13,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179 [H]

Pfam domain/function: PF00254 FKBP_C [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 7012; Mature: 7012

Theoretical pI: Translated: 7.81; Mature: 7.81

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGTGRVIKGWDIGLMGMKVGGKRRLFVPAHLGYGERQIGAHIPPNSDLHFEIELLEVLT
CCCCCCEECCCCCEEEEEEECCCEEEEEECCCCCCCCCCCCCCCCCCCCEEEEEEEEEEE
RDD
CCC
>Mature Secondary Structure
MIGTGRVIKGWDIGLMGMKVGGKRRLFVPAHLGYGERQIGAHIPPNSDLHFEIELLEVLT
CCCCCCEECCCCCEEEEEEECCCEEEEEECCCCCCCCCCCCCCCCCCCCEEEEEEEEEEE
RDD
CCC

PDB accession: NA

Resolution: NA

Structure class: Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]