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The map label for this gene is pcoA [H]

Identifier: 146283054

GI number: 146283054

Start: 2938501

End: 2939958

Strand: Direct

Name: pcoA [H]

Synonym: PST_2715

Alternate gene names: 146283054

Gene position: 2938501-2939958 (Clockwise)

Preceding gene: 146283053

Following gene: 146283055

Centisome position: 64.34

GC content: 66.87

Gene sequence:

>1458_bases
ATGGACGGCGTGCCCGGCTTCAGCTTCGCCGGCATCGCGCCGGACGGCATGTACGAGTACCGCTTCAAGGTCAAGCAGAG
CGGGACCTACTGGTATCACAGCCACTCGGGCTTCCAGGAGCAGCTCGGCGTCTACGGCCCGCTGATCATCGATCCCGAGG
AGCCCGAGCCGTTCGCCTACGAGCGAGACTATGTGGTGTTTCTCTCCGACTGGACCGACGAGAGCCCGGCGCGCGTCCTG
GCCAAGCTGAAGAAGCAGGCCGACTACTACAACCAGGGCCGCCGCACCGTCGGCGACTTCATCAACGATGTCGCCGACCA
GGGCTGGCGCAAGACCTTCAGCGACCGCTGGGCCTGGGCGAAGATGAACATGTCGCCCACCGATCTCGCCGACGTCAGCG
GCGCGACCTACACCTACCTGCTCAACGGCCAGGCCCCGGACGGCAACTGGACCGGGCTGTTCCGGCCGGGCGAGCGCATC
CGCCTGCGCCTGATCAACGGCTCGGCGATGAGCTACTTCGACTTCCGTATTCCCGGCCTCAAGCTCACCGTGGTCGCCGC
GGACGGGCAGAACATCGAGCCGGTAACGGTCGACGAGATTCGCCTGGCGGTGGCGGAAACCTATGACGTGATCGTCGAGC
CGGACGGCAGCCAGCACGCCTACACCCTCTTCGCCCAGGCCATGGACCGCAGCGGCTACGCCCGCGGCACGCTGGCCGTG
CGCGAAGGCCTGCAGGCCCCGGTGCCCAACCCCGATCCGCGCCCCGAACTGACCATGGACGACATGGGTCATGGCGATCA
CGCCGCCCATGGCCAGGCTGCCGCAACGCCCGCGCAGGGCCATGACGCCCATGCCGGACACGGCGACCATGGCGCGATGG
ATCACGGCCAGATGAACCATGCCGCCATGGGCCAGGGCTCGGATGGCAGCAGGATGCAGGCACATCCGGCCAGCGAGACC
AACAACCCTCTGGTGGACATGCAGACCATGATGCCGGTGGCCAAGCTGGATGACCCGGGCATCGGCCTGCGCGCCAACGG
CCGGCGCGTGCTGACCTATGCCGACTTGCGCAGCGCCTTCGCCGACCCGGATGGCCGCGAACCGGGCCGCACCATCGAAC
TGCACCTGACCGGCCACATGGAGCGCTTCTCCTGGTCGTTCGACGGTATTCCCTTCGCCGACGCCGAGCCGATCCGCCTC
CGGTACGGCGAGCGGGTGCGCTTCGTACTGGTCAACGACACCATGATGCACCACCCCATTCACCTGCACGGGCTGTGGAG
TGACCTGGAGGACGAACACGGCGACTTCCTGGTGCGCAAGCACACCATCGACATGCCGCCGGGCTCGAAACGCAGCTACC
GCGTCACAGCAGACGCCCTCGGCCGCTGGGCCTACCACTGCCACATGCTGATGCACATGGACCTCGGAATGTTCCGTGAA
GTCCGCGTAGAGGAATGA

Upstream 100 bases:

>100_bases
TGCTGCGCTGGCGCGAGGGTGACACCGTGACCCTGCGCGTGCGCAACCGCCTGCCGCAGGAGACCTCGACCACTGGCACG
GCATCCTGCTGCCGGCCAAC

Downstream 100 bases:

>100_bases
CGGAGATGCCTATGAAAACCCTCAAGCACACCACCCTGCTCGCCCTCGGCCTGGCCGCCTCCCTCGGCCTGAACGCGGTC
CAGGCGCAGCAGAGCGAACA

Product: copper resistance protein A precursor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 485; Mature: 485

Protein sequence:

>485_residues
MDGVPGFSFAGIAPDGMYEYRFKVKQSGTYWYHSHSGFQEQLGVYGPLIIDPEEPEPFAYERDYVVFLSDWTDESPARVL
AKLKKQADYYNQGRRTVGDFINDVADQGWRKTFSDRWAWAKMNMSPTDLADVSGATYTYLLNGQAPDGNWTGLFRPGERI
RLRLINGSAMSYFDFRIPGLKLTVVAADGQNIEPVTVDEIRLAVAETYDVIVEPDGSQHAYTLFAQAMDRSGYARGTLAV
REGLQAPVPNPDPRPELTMDDMGHGDHAAHGQAAATPAQGHDAHAGHGDHGAMDHGQMNHAAMGQGSDGSRMQAHPASET
NNPLVDMQTMMPVAKLDDPGIGLRANGRRVLTYADLRSAFADPDGREPGRTIELHLTGHMERFSWSFDGIPFADAEPIRL
RYGERVRFVLVNDTMMHHPIHLHGLWSDLEDEHGDFLVRKHTIDMPPGSKRSYRVTADALGRWAYHCHMLMHMDLGMFRE
VRVEE

Sequences:

>Translated_485_residues
MDGVPGFSFAGIAPDGMYEYRFKVKQSGTYWYHSHSGFQEQLGVYGPLIIDPEEPEPFAYERDYVVFLSDWTDESPARVL
AKLKKQADYYNQGRRTVGDFINDVADQGWRKTFSDRWAWAKMNMSPTDLADVSGATYTYLLNGQAPDGNWTGLFRPGERI
RLRLINGSAMSYFDFRIPGLKLTVVAADGQNIEPVTVDEIRLAVAETYDVIVEPDGSQHAYTLFAQAMDRSGYARGTLAV
REGLQAPVPNPDPRPELTMDDMGHGDHAAHGQAAATPAQGHDAHAGHGDHGAMDHGQMNHAAMGQGSDGSRMQAHPASET
NNPLVDMQTMMPVAKLDDPGIGLRANGRRVLTYADLRSAFADPDGREPGRTIELHLTGHMERFSWSFDGIPFADAEPIRL
RYGERVRFVLVNDTMMHHPIHLHGLWSDLEDEHGDFLVRKHTIDMPPGSKRSYRVTADALGRWAYHCHMLMHMDLGMFRE
VRVEE
>Mature_485_residues
MDGVPGFSFAGIAPDGMYEYRFKVKQSGTYWYHSHSGFQEQLGVYGPLIIDPEEPEPFAYERDYVVFLSDWTDESPARVL
AKLKKQADYYNQGRRTVGDFINDVADQGWRKTFSDRWAWAKMNMSPTDLADVSGATYTYLLNGQAPDGNWTGLFRPGERI
RLRLINGSAMSYFDFRIPGLKLTVVAADGQNIEPVTVDEIRLAVAETYDVIVEPDGSQHAYTLFAQAMDRSGYARGTLAV
REGLQAPVPNPDPRPELTMDDMGHGDHAAHGQAAATPAQGHDAHAGHGDHGAMDHGQMNHAAMGQGSDGSRMQAHPASET
NNPLVDMQTMMPVAKLDDPGIGLRANGRRVLTYADLRSAFADPDGREPGRTIELHLTGHMERFSWSFDGIPFADAEPIRL
RYGERVRFVLVNDTMMHHPIHLHGLWSDLEDEHGDFLVRKHTIDMPPGSKRSYRVTADALGRWAYHCHMLMHMDLGMFRE
VRVEE

Specific function: Could be involved in copper resistance. May have oxidase activity [H]

COG id: COG2132

COG function: function code Q; Putative multicopper oxidases

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multicopper oxidase family. CopA subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001117
- InterPro:   IPR011706
- InterPro:   IPR011707
- InterPro:   IPR006376
- InterPro:   IPR002355
- InterPro:   IPR008972
- InterPro:   IPR006311 [H]

Pfam domain/function: PF00394 Cu-oxidase; PF07731 Cu-oxidase_2; PF07732 Cu-oxidase_3 [H]

EC number: NA

Molecular weight: Translated: 54257; Mature: 54257

Theoretical pI: Translated: 5.70; Mature: 5.70

Prosite motif: PS00080 MULTICOPPER_OXIDASE2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDGVPGFSFAGIAPDGMYEYRFKVKQSGTYWYHSHSGFQEQLGVYGPLIIDPEEPEPFAY
CCCCCCCCCCCCCCCCCEEEEEEEEECCEEEEECCCCHHHHHCCCCCEEECCCCCCCCEE
ERDYVVFLSDWTDESPARVLAKLKKQADYYNQGRRTVGDFINDVADQGWRKTFSDRWAWA
CCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCEEEE
KMNMSPTDLADVSGATYTYLLNGQAPDGNWTGLFRPGERIRLRLINGSAMSYFDFRIPGL
ECCCCCCCHHHCCCCEEEEEEECCCCCCCEEEEECCCCEEEEEEEECCCEEEEEEECCCE
KLTVVAADGQNIEPVTVDEIRLAVAETYDVIVEPDGSQHAYTLFAQAMDRSGYARGTLAV
EEEEEEECCCCCCCEEHHHHHEEEEEEEEEEECCCCCCHHHHHHHHHHCCCCCCCCHHHH
REGLQAPVPNPDPRPELTMDDMGHGDHAAHGQAAATPAQGHDAHAGHGDHGAMDHGQMNH
HCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
AAMGQGSDGSRMQAHPASETNNPLVDMQTMMPVAKLDDPGIGLRANGRRVLTYADLRSAF
CCCCCCCCCCCEEECCCCCCCCCEEEHHHHCCHHHCCCCCCCEEECCCEEEEEHHHHHHH
ADPDGREPGRTIELHLTGHMERFSWSFDGIPFADAEPIRLRYGERVRFVLVNDTMMHHPI
CCCCCCCCCCEEEEEEEECCEEEEECCCCCCCCCCCCEEEECCCEEEEEEEECCEECCCE
HLHGLWSDLEDEHGDFLVRKHTIDMPPGSKRSYRVTADALGRWAYHCHMLMHMDLGMFRE
EEEECCCCCCCCCCCEEEEEEEECCCCCCCCEEEEEHHHHHHHHHHHHHHHHHCCCHHHH
VRVEE
EEECC
>Mature Secondary Structure
MDGVPGFSFAGIAPDGMYEYRFKVKQSGTYWYHSHSGFQEQLGVYGPLIIDPEEPEPFAY
CCCCCCCCCCCCCCCCCEEEEEEEEECCEEEEECCCCHHHHHCCCCCEEECCCCCCCCEE
ERDYVVFLSDWTDESPARVLAKLKKQADYYNQGRRTVGDFINDVADQGWRKTFSDRWAWA
CCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCEEEE
KMNMSPTDLADVSGATYTYLLNGQAPDGNWTGLFRPGERIRLRLINGSAMSYFDFRIPGL
ECCCCCCCHHHCCCCEEEEEEECCCCCCCEEEEECCCCEEEEEEEECCCEEEEEEECCCE
KLTVVAADGQNIEPVTVDEIRLAVAETYDVIVEPDGSQHAYTLFAQAMDRSGYARGTLAV
EEEEEEECCCCCCCEEHHHHHEEEEEEEEEEECCCCCCHHHHHHHHHHCCCCCCCCHHHH
REGLQAPVPNPDPRPELTMDDMGHGDHAAHGQAAATPAQGHDAHAGHGDHGAMDHGQMNH
HCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
AAMGQGSDGSRMQAHPASETNNPLVDMQTMMPVAKLDDPGIGLRANGRRVLTYADLRSAF
CCCCCCCCCCCEEECCCCCCCCCEEEHHHHCCHHHCCCCCCCEEECCCEEEEEHHHHHHH
ADPDGREPGRTIELHLTGHMERFSWSFDGIPFADAEPIRLRYGERVRFVLVNDTMMHHPI
CCCCCCCCCCEEEEEEEECCEEEEECCCCCCCCCCCCEEEECCCEEEEEEEECCEECCCE
HLHGLWSDLEDEHGDFLVRKHTIDMPPGSKRSYRVTADALGRWAYHCHMLMHMDLGMFRE
EEEECCCCCCCCCCCEEEEEEEECCCCCCCCEEEEEHHHHHHHHHHHHHHHHHCCCHHHH
VRVEE
EEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12928499 [H]