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The map label for this gene is rrmA [H]

Identifier: 146283030

GI number: 146283030

Start: 2916444

End: 2917199

Strand: Direct

Name: rrmA [H]

Synonym: PST_2691

Alternate gene names: 146283030

Gene position: 2916444-2917199 (Clockwise)

Preceding gene: 146283029

Following gene: 146283031

Centisome position: 63.85

GC content: 70.63

Gene sequence:

>756_bases
GTGGCCTGCCCGGCCAACCACCGTTTCGACCGCGCGCGCCAGGGCTACCTGAACCTGCTGCCCGTGCAGCACAAGAACAG
CCGCGATCCGGGCGACAACCAGGCGATGGTCGAGGCGCGCCGGCGCTTTCTCGATGGCGGTCACTATGCGCCGCTGGCCC
GACGCCTCGCCGAGCTGGCCGCCGAGCGCGCGCCGCAACGCTGGCTGGACATCGGCTGTGGCGAGGGCTACTACACAGCC
CAACTGGCCGCCGCGCTGCCGGATGCAGAAGGCTACGCACTGGACATCTCCCGCGAGGCGATCAAGCGCGCCTGCAAACG
CGCCCCGCAACTCGAGTGGCTGGTGGCGAGCATGGCCCGCGTGCCGCTGGCCGATGCCAGCTGCGACCTGCTGGCCAGCG
TGTTCAGCCCGCTGGACTGGCAGGAAGCGCGACGCCTGCTCCCGCCCGGCGGCGGACTGCTGCGCATGGGGCCGACCCGC
GAGCACCTCTGGGAGCTGCGCGCGCGGCTCTACGACGAGGTACGCGACTACGACGACGAGAAGCACCTGTCGCTCATTCC
GGACGGCATGCGCCTGACCCACAGCGAAACCCTCAGCTATGAACTGCAGCTGGACGACGCCCAGGCCCGCGCCGACCTCC
TGGCGATGACCCCGCACGGCTGGCGCGCCAGCGCCGAGCGGCGCGCCGCCGTCATCGACACGCCGCTGGCGGTGCGGGTT
GCGATACGCTACGACTGGATCGAACGAATTTCCTAA

Upstream 100 bases:

>100_bases
TCGATGTGCTGACCGACATCTACTACCAGACCCTGGTGAACCTGCTGGCATGCTGATCTGCCCGATCTGCCAGGCGCCGC
TCAGCGCGGTGGAAAACGGC

Downstream 100 bases:

>100_bases
GGCAAACGCCTCGATAGCATGCGAGGCAGGCCAAGGCACAACACAGAAGGCAGTCGCCCATGCGTCAACCCGATATCGAG
ATCTACCTCAGGGATGCCAG

Product: rRNA methyltransferase

Products: NA

Alternate protein names: 23S rRNA m1G745 methyltransferase; rRNA (guanine-N(1)-)-methyltransferase [H]

Number of amino acids: Translated: 251; Mature: 250

Protein sequence:

>251_residues
MACPANHRFDRARQGYLNLLPVQHKNSRDPGDNQAMVEARRRFLDGGHYAPLARRLAELAAERAPQRWLDIGCGEGYYTA
QLAAALPDAEGYALDISREAIKRACKRAPQLEWLVASMARVPLADASCDLLASVFSPLDWQEARRLLPPGGGLLRMGPTR
EHLWELRARLYDEVRDYDDEKHLSLIPDGMRLTHSETLSYELQLDDAQARADLLAMTPHGWRASAERRAAVIDTPLAVRV
AIRYDWIERIS

Sequences:

>Translated_251_residues
MACPANHRFDRARQGYLNLLPVQHKNSRDPGDNQAMVEARRRFLDGGHYAPLARRLAELAAERAPQRWLDIGCGEGYYTA
QLAAALPDAEGYALDISREAIKRACKRAPQLEWLVASMARVPLADASCDLLASVFSPLDWQEARRLLPPGGGLLRMGPTR
EHLWELRARLYDEVRDYDDEKHLSLIPDGMRLTHSETLSYELQLDDAQARADLLAMTPHGWRASAERRAAVIDTPLAVRV
AIRYDWIERIS
>Mature_250_residues
ACPANHRFDRARQGYLNLLPVQHKNSRDPGDNQAMVEARRRFLDGGHYAPLARRLAELAAERAPQRWLDIGCGEGYYTAQ
LAAALPDAEGYALDISREAIKRACKRAPQLEWLVASMARVPLADASCDLLASVFSPLDWQEARRLLPPGGGLLRMGPTRE
HLWELRARLYDEVRDYDDEKHLSLIPDGMRLTHSETLSYELQLDDAQARADLLAMTPHGWRASAERRAAVIDTPLAVRVA
IRYDWIERIS

Specific function: Specifically methylates the guanosine in position 745 of 23S rRNA [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RlmA family [H]

Homologues:

Organism=Escherichia coli, GI1788125, Length=227, Percent_Identity=44.9339207048458, Blast_Score=187, Evalue=7e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013216
- InterPro:   IPR016718 [H]

Pfam domain/function: PF08241 Methyltransf_11 [H]

EC number: =2.1.1.187 [H]

Molecular weight: Translated: 28363; Mature: 28231

Theoretical pI: Translated: 6.88; Mature: 6.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MACPANHRFDRARQGYLNLLPVQHKNSRDPGDNQAMVEARRRFLDGGHYAPLARRLAELA
CCCCCCCCHHHHHCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHH
AERAPQRWLDIGCGEGYYTAQLAAALPDAEGYALDISREAIKRACKRAPQLEWLVASMAR
HHHCCHHHHCCCCCCCHHHHHHHHHCCCCCCCEEECCHHHHHHHHHHCCCHHHHHHHHHH
VPLADASCDLLASVFSPLDWQEARRLLPPGGGLLRMGPTREHLWELRARLYDEVRDYDDE
CCCCCCHHHHHHHHHCCCCHHHHHHCCCCCCCEEECCCCHHHHHHHHHHHHHHHHCCCCC
KHLSLIPDGMRLTHSETLSYELQLDDAQARADLLAMTPHGWRASAERRAAVIDTPLAVRV
CCEEECCCCCEEECCCCEEEEEEECCHHHHHHEEEECCCCCCCCHHCCCEEECCCCEEEE
AIRYDWIERIS
EHHHHHHHHCC
>Mature Secondary Structure 
ACPANHRFDRARQGYLNLLPVQHKNSRDPGDNQAMVEARRRFLDGGHYAPLARRLAELA
CCCCCCCHHHHHCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHH
AERAPQRWLDIGCGEGYYTAQLAAALPDAEGYALDISREAIKRACKRAPQLEWLVASMAR
HHHCCHHHHCCCCCCCHHHHHHHHHCCCCCCCEEECCHHHHHHHHHHCCCHHHHHHHHHH
VPLADASCDLLASVFSPLDWQEARRLLPPGGGLLRMGPTREHLWELRARLYDEVRDYDDE
CCCCCCHHHHHHHHHCCCCHHHHHHCCCCCCCEEECCCCHHHHHHHHHHHHHHHHCCCCC
KHLSLIPDGMRLTHSETLSYELQLDDAQARADLLAMTPHGWRASAERRAAVIDTPLAVRV
CCEEECCCCCEEECCCCEEEEEEECCHHHHHHEEEECCCCCCCCHHCCCEEECCCCEEEE
AIRYDWIERIS
EHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7984109; 9097040; 9278503; 9440525 [H]