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The map label for this gene is 146283005

Identifier: 146283005

GI number: 146283005

Start: 2889040

End: 2890374

Strand: Direct

Name: 146283005

Synonym: PST_2666

Alternate gene names: NA

Gene position: 2889040-2890374 (Clockwise)

Preceding gene: 146283003

Following gene: 146283012

Centisome position: 63.25

GC content: 66.97

Gene sequence:

>1335_bases
ATGAGCGCCTCCCGTGCACATTCATCCGAGCCATCCGAGGATCAGCTGGTCGCCCTGCTGCGCCAGCATGCCGAGCCCCT
GCCCGCCCTGGACGAACCGCGCTTCGCCGACGCCTTCGAGCGCTACGCCGACGCTCGGGTCGTGCTGATCGGTGAGGCCA
GCCATGGCACTTCCGAGTTCTATCGGGCCCGCGCCGCGATCACCCGGCGGCTGATCGAACAGCACGGGTTTTCCATCGTC
GCGGTCGAGGCGGACTGGCCCGATGCCGCGCGCATCGACTGCCATTGTCGGCAGCGCGAGCCCGTCGCCTGGGCCGAAAA
TGCCTTCAAGCGCTTCCCGAGCTGGATGTGGCGCAATCGCGAGGTCGACGGCTTCGTGCGCTGGCTGCGTGAACACAATG
CCGCGCTGACCGCCGAGCAGCGCGTCGAGTTTCGCGGCCTGGACGTCTACAGCCTCGGCAGCTCGATGCGCGAAGTGCTG
GATTATCTGGATCGCACCGATCCGGCGGCCGCCGCCGCTGCCCGGCGGCGCTATGGTTGCCTGAGCCCCTGGCAGGAAGA
TCCGGCCGACTATGGCCGCAACGTCATGCTCGGCCAGCCTTCCTGCGAAAACGCCGTCATTGAACAACTGCAGGCTCTGC
TCACCCAGCGCCTGGCGTACATCGACCAGGACGGCGAGCGCTTCTTCAATGCCGAACGCAACGCGCGGGTGGTGCTTGCC
GCGGAGCACTACTATCGAGCGATGTACCGCGGCTCGACGGAGTCCTGGAATCTGCGCGACCGGCACATGTTCGATACGCT
GCGTGCCCTACTCGATCATCGCGGCGCGGATGCCAAGGCAGTGGTCTGGGCGCATAACTCGCACATCGGCAATGCCGCGG
CGACCTCGATGGGCTGGGGGGGCGAATTCAATATCGGCGAACTCTGCCGCACGGCCTTCGGCCGCGACGCGGTGTTGATC
GGCATGGCGACCGACCGCGGCGAGGTGGCCGCGGCGGACAACTGGGACGAGCCGATGCGGCGCAAGCAGGTCATCCCGTC
GCGGCCCGACAGTTGGGAGCAGCTGTTCCTACGGGCCGGCGTGCCGGCATCACTGACCGATTGGCGGGATGATCGGGGCA
AGCTGCGCGAGGCACTCAGCCATCCACGACTGGAGCGTGCGATCGGCGTCATCTACCGGCCTCTGACGGAGCGGCAGAGT
CATTACTTTCGCGCCATCCTGGCCGAGCAGTTCGACGCGCTGATCTGGCTGGAGCAGACGCAGGCGGTGACGCCCATCGG
CTCGCAGGACATCGACGCGAGCGTCGTGCCGGATACCTACCCGTTCGGGGAGTAA

Upstream 100 bases:

>100_bases
ACCTCAAAGTTAGCAGCTTTAATTGCAGGACGAGGAACAACCCTCCGGATGGCCAGTCATCCGTGGTGTCCTTGTTCGAC
GAGAAGAATGAGTCCGACCC

Downstream 100 bases:

>100_bases
GCCTGCGTCGCGGCACCGGAGCGCTGCGACGCAGTCATGCATGAAGAGACCGACAGCCGGCTTATGCCACCGGCGCGGGT
GGTGGTTGATCCGGCACGGT

Product: protein-L-isoaspartate O-methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 444; Mature: 443

Protein sequence:

>444_residues
MSASRAHSSEPSEDQLVALLRQHAEPLPALDEPRFADAFERYADARVVLIGEASHGTSEFYRARAAITRRLIEQHGFSIV
AVEADWPDAARIDCHCRQREPVAWAENAFKRFPSWMWRNREVDGFVRWLREHNAALTAEQRVEFRGLDVYSLGSSMREVL
DYLDRTDPAAAAAARRRYGCLSPWQEDPADYGRNVMLGQPSCENAVIEQLQALLTQRLAYIDQDGERFFNAERNARVVLA
AEHYYRAMYRGSTESWNLRDRHMFDTLRALLDHRGADAKAVVWAHNSHIGNAAATSMGWGGEFNIGELCRTAFGRDAVLI
GMATDRGEVAAADNWDEPMRRKQVIPSRPDSWEQLFLRAGVPASLTDWRDDRGKLREALSHPRLERAIGVIYRPLTERQS
HYFRAILAEQFDALIWLEQTQAVTPIGSQDIDASVVPDTYPFGE

Sequences:

>Translated_444_residues
MSASRAHSSEPSEDQLVALLRQHAEPLPALDEPRFADAFERYADARVVLIGEASHGTSEFYRARAAITRRLIEQHGFSIV
AVEADWPDAARIDCHCRQREPVAWAENAFKRFPSWMWRNREVDGFVRWLREHNAALTAEQRVEFRGLDVYSLGSSMREVL
DYLDRTDPAAAAAARRRYGCLSPWQEDPADYGRNVMLGQPSCENAVIEQLQALLTQRLAYIDQDGERFFNAERNARVVLA
AEHYYRAMYRGSTESWNLRDRHMFDTLRALLDHRGADAKAVVWAHNSHIGNAAATSMGWGGEFNIGELCRTAFGRDAVLI
GMATDRGEVAAADNWDEPMRRKQVIPSRPDSWEQLFLRAGVPASLTDWRDDRGKLREALSHPRLERAIGVIYRPLTERQS
HYFRAILAEQFDALIWLEQTQAVTPIGSQDIDASVVPDTYPFGE
>Mature_443_residues
SASRAHSSEPSEDQLVALLRQHAEPLPALDEPRFADAFERYADARVVLIGEASHGTSEFYRARAAITRRLIEQHGFSIVA
VEADWPDAARIDCHCRQREPVAWAENAFKRFPSWMWRNREVDGFVRWLREHNAALTAEQRVEFRGLDVYSLGSSMREVLD
YLDRTDPAAAAAARRRYGCLSPWQEDPADYGRNVMLGQPSCENAVIEQLQALLTQRLAYIDQDGERFFNAERNARVVLAA
EHYYRAMYRGSTESWNLRDRHMFDTLRALLDHRGADAKAVVWAHNSHIGNAAATSMGWGGEFNIGELCRTAFGRDAVLIG
MATDRGEVAAADNWDEPMRRKQVIPSRPDSWEQLFLRAGVPASLTDWRDDRGKLREALSHPRLERAIGVIYRPLTERQSH
YFRAILAEQFDALIWLEQTQAVTPIGSQDIDASVVPDTYPFGE

Specific function: Unknown

COG id: COG2312

COG function: function code R; Erythromycin esterase homolog

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: In the N-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007815
- InterPro:   IPR000836 [H]

Pfam domain/function: PF05139 Erythro_esteras; PF00156 Pribosyltran [H]

EC number: NA

Molecular weight: Translated: 50486; Mature: 50355

Theoretical pI: Translated: 5.78; Mature: 5.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSASRAHSSEPSEDQLVALLRQHAEPLPALDEPRFADAFERYADARVVLIGEASHGTSEF
CCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCEEEEEECCCCCHHHH
YRARAAITRRLIEQHGFSIVAVEADWPDAARIDCHCRQREPVAWAENAFKRFPSWMWRNR
HHHHHHHHHHHHHHCCCEEEEEECCCCCCCCEECCCCCCCCCHHHHHHHHHHHHHHHCCC
EVDGFVRWLREHNAALTAEQRVEFRGLDVYSLGSSMREVLDYLDRTDPAAAAAARRRYGC
CHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCC
LSPWQEDPADYGRNVMLGQPSCENAVIEQLQALLTQRLAYIDQDGERFFNAERNARVVLA
CCCCCCCHHHHCCEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCEEEEE
AEHYYRAMYRGSTESWNLRDRHMFDTLRALLDHRGADAKAVVWAHNSHIGNAAATSMGWG
HHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCHHHHCCCCC
GEFNIGELCRTAFGRDAVLIGMATDRGEVAAADNWDEPMRRKQVIPSRPDSWEQLFLRAG
CCCCHHHHHHHHCCCCEEEEEEECCCCCEEECCCCHHHHHHHCCCCCCCCHHHHHHHHCC
VPASLTDWRDDRGKLREALSHPRLERAIGVIYRPLTERQSHYFRAILAEQFDALIWLEQT
CCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECC
QAVTPIGSQDIDASVVPDTYPFGE
CCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SASRAHSSEPSEDQLVALLRQHAEPLPALDEPRFADAFERYADARVVLIGEASHGTSEF
CCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCEEEEEECCCCCHHHH
YRARAAITRRLIEQHGFSIVAVEADWPDAARIDCHCRQREPVAWAENAFKRFPSWMWRNR
HHHHHHHHHHHHHHCCCEEEEEECCCCCCCCEECCCCCCCCCHHHHHHHHHHHHHHHCCC
EVDGFVRWLREHNAALTAEQRVEFRGLDVYSLGSSMREVLDYLDRTDPAAAAAARRRYGC
CHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCC
LSPWQEDPADYGRNVMLGQPSCENAVIEQLQALLTQRLAYIDQDGERFFNAERNARVVLA
CCCCCCCHHHHCCEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCEEEEE
AEHYYRAMYRGSTESWNLRDRHMFDTLRALLDHRGADAKAVVWAHNSHIGNAAATSMGWG
HHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCHHHHCCCCC
GEFNIGELCRTAFGRDAVLIGMATDRGEVAAADNWDEPMRRKQVIPSRPDSWEQLFLRAG
CCCCHHHHHHHHCCCCEEEEEEECCCCCEEECCCCHHHHHHHCCCCCCCCHHHHHHHHCC
VPASLTDWRDDRGKLREALSHPRLERAIGVIYRPLTERQSHYFRAILAEQFDALIWLEQT
CCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECC
QAVTPIGSQDIDASVVPDTYPFGE
CCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]