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The map label for this gene is yfbQ [H]

Identifier: 146282876

GI number: 146282876

Start: 2764257

End: 2765468

Strand: Direct

Name: yfbQ [H]

Synonym: PST_2537

Alternate gene names: 146282876

Gene position: 2764257-2765468 (Clockwise)

Preceding gene: 146282872

Following gene: 146282877

Centisome position: 60.52

GC content: 61.06

Gene sequence:

>1212_bases
ATGCAGGTCAGCAAATCGAACAAGCTCGCCAATGTCTGTTACGACATCCGTGGGCCAGTGCTCAAGCACGCCAAACGCCT
GGAAGAGGAAGGCCATCGCATCCTCAAGCTGAACATCGGCAACCCGGCGCCGTTCGGTTTCGAAGCACCGGAGGAAATTC
TCCAGGACGTGATCCGCAACCTGCCGACCGCCCAGGGCTACAGCGACTCGAAAGGCCTGTTCAGCGCCCGCAAGGCGATC
ATGCAGTACTACCAGCAAAAGCAGGTGGAAGGCATCGGCATCGAGGACATCTATCTCGGCAACGGCGTGTCCGAGCTGAT
CGTGATGTCCATGCAGGCGTTGCTCAACAACGGCGACGAAGTGCTGATCCCCGCTCCGGACTATCCGCTCTGGACGGCCG
CCGTGAGCCTGGCCGGCGGCAAGCCGGTGCATTACCTCTGCGACGAACAGGCCAACTGGTGGCCCGACCTGGCCGACATC
AAGGCCAAGATCACGCCAAACACCAAGGCGCTGGTCCTGATCAACCCGAACAACCCCACCGGCGCGGTCTATCCGAAGGA
AGTCCTGGAAGGCATGGTGGAGCTGGCTCGCCAGCACAAGCTGGTGCTGTTCTCCGACGAGATCTACGACAAGATTCTCT
ATGACGGCGCGGTGCACATCTCCACCGCCTCGCTGGCGCCGGACGTGCTCTGCTTGACCTTCAACGGCTTGTCCAAGTCC
TATCGTGTCGCCGGCTTCCGCTCCGGCTGGGTGGCTATCTCCGGCCCCAAACACAAGGCCCAGAGTTATATCGAAGGCCT
GGATATCCTTGCCAACATGCGCCTGTGCGCCAACGTACCATCGCAGCATGCGATTCAGACGGCACTGGGCGGCTATCAGA
GCATCAATGACCTGGTCCTGCCGCCGGGTCGGCTGCTCGAGCAGCGCAACCGCACCTGGGAGCTGCTCAACGACATTCCC
GGCATCAGCTGCGTCAAGCCCATGGGCGCGCTGTATGCGTTCCCGCGCATCGATCCGAAGATCTGCCCGATTCACAACGA
CGAGAAGTTCGTGCTCGACCTGCTGCTTTCCGAGAAACTGCTGATTGTCCAGGGCACGGCATTCAACTGGCCGTGGCCGG
ATCACTTCCGGGTGGTTACCCTGCCGCGCGTGGATGACCTGGAGCAGGCGATCGGACGCATCGGCAACTTCCTCAAGACC
TACCAGCAGTAA

Upstream 100 bases:

>100_bases
TGGCAGCGGGGTTTCCGACTGCCAAGGCGCCCGGGTTCATGCCAAACGTGACCAGCCATTTCCGGAACTGGCACGTTTTC
ACTTCGGGACACTCAGGATC

Downstream 100 bases:

>100_bases
CCGAATGGATCTGCAGATAGACGACTTCTACAAGGACGCCGCGGGCGGTCTGCTCGCGTTGTATCAGGCGTTTCCACGGA
AGATCGCGCTGTATGTGGAA

Product: aminotransferase AlaT

Products: oxaloacetate; L-glutamate

Alternate protein names: NA

Number of amino acids: Translated: 403; Mature: 403

Protein sequence:

>403_residues
MQVSKSNKLANVCYDIRGPVLKHAKRLEEEGHRILKLNIGNPAPFGFEAPEEILQDVIRNLPTAQGYSDSKGLFSARKAI
MQYYQQKQVEGIGIEDIYLGNGVSELIVMSMQALLNNGDEVLIPAPDYPLWTAAVSLAGGKPVHYLCDEQANWWPDLADI
KAKITPNTKALVLINPNNPTGAVYPKEVLEGMVELARQHKLVLFSDEIYDKILYDGAVHISTASLAPDVLCLTFNGLSKS
YRVAGFRSGWVAISGPKHKAQSYIEGLDILANMRLCANVPSQHAIQTALGGYQSINDLVLPPGRLLEQRNRTWELLNDIP
GISCVKPMGALYAFPRIDPKICPIHNDEKFVLDLLLSEKLLIVQGTAFNWPWPDHFRVVTLPRVDDLEQAIGRIGNFLKT
YQQ

Sequences:

>Translated_403_residues
MQVSKSNKLANVCYDIRGPVLKHAKRLEEEGHRILKLNIGNPAPFGFEAPEEILQDVIRNLPTAQGYSDSKGLFSARKAI
MQYYQQKQVEGIGIEDIYLGNGVSELIVMSMQALLNNGDEVLIPAPDYPLWTAAVSLAGGKPVHYLCDEQANWWPDLADI
KAKITPNTKALVLINPNNPTGAVYPKEVLEGMVELARQHKLVLFSDEIYDKILYDGAVHISTASLAPDVLCLTFNGLSKS
YRVAGFRSGWVAISGPKHKAQSYIEGLDILANMRLCANVPSQHAIQTALGGYQSINDLVLPPGRLLEQRNRTWELLNDIP
GISCVKPMGALYAFPRIDPKICPIHNDEKFVLDLLLSEKLLIVQGTAFNWPWPDHFRVVTLPRVDDLEQAIGRIGNFLKT
YQQ
>Mature_403_residues
MQVSKSNKLANVCYDIRGPVLKHAKRLEEEGHRILKLNIGNPAPFGFEAPEEILQDVIRNLPTAQGYSDSKGLFSARKAI
MQYYQQKQVEGIGIEDIYLGNGVSELIVMSMQALLNNGDEVLIPAPDYPLWTAAVSLAGGKPVHYLCDEQANWWPDLADI
KAKITPNTKALVLINPNNPTGAVYPKEVLEGMVELARQHKLVLFSDEIYDKILYDGAVHISTASLAPDVLCLTFNGLSKS
YRVAGFRSGWVAISGPKHKAQSYIEGLDILANMRLCANVPSQHAIQTALGGYQSINDLVLPPGRLLEQRNRTWELLNDIP
GISCVKPMGALYAFPRIDPKICPIHNDEKFVLDLLLSEKLLIVQGTAFNWPWPDHFRVVTLPRVDDLEQAIGRIGNFLKT
YQQ

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI19263340, Length=483, Percent_Identity=26.7080745341615, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI4507369, Length=377, Percent_Identity=28.3819628647215, Blast_Score=129, Evalue=6e-30,
Organism=Homo sapiens, GI4885351, Length=448, Percent_Identity=25.8928571428571, Blast_Score=127, Evalue=1e-29,
Organism=Homo sapiens, GI215599424, Length=407, Percent_Identity=28.2555282555283, Blast_Score=126, Evalue=4e-29,
Organism=Homo sapiens, GI95147551, Length=243, Percent_Identity=30.4526748971193, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI169881279, Length=243, Percent_Identity=30.4526748971193, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI56713256, Length=332, Percent_Identity=27.1084337349398, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI56713254, Length=332, Percent_Identity=27.1084337349398, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI169881281, Length=150, Percent_Identity=36.6666666666667, Blast_Score=91, Evalue=2e-18,
Organism=Escherichia coli, GI1788627, Length=401, Percent_Identity=72.069825436409, Blast_Score=630, Evalue=0.0,
Organism=Escherichia coli, GI1788722, Length=408, Percent_Identity=25.9803921568627, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1786816, Length=243, Percent_Identity=25.1028806584362, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1787909, Length=219, Percent_Identity=24.2009132420091, Blast_Score=63, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17567663, Length=370, Percent_Identity=30, Blast_Score=157, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI71981209, Length=466, Percent_Identity=25.5364806866953, Blast_Score=116, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI71994476, Length=184, Percent_Identity=33.1521739130435, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI71981215, Length=294, Percent_Identity=27.2108843537415, Blast_Score=93, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI71994472, Length=184, Percent_Identity=33.1521739130435, Blast_Score=93, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17567369, Length=234, Percent_Identity=27.7777777777778, Blast_Score=83, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6320317, Length=450, Percent_Identity=27.5555555555556, Blast_Score=115, Evalue=1e-26,
Organism=Saccharomyces cerevisiae, GI6323118, Length=362, Percent_Identity=27.0718232044199, Blast_Score=113, Evalue=7e-26,
Organism=Saccharomyces cerevisiae, GI6322401, Length=282, Percent_Identity=26.241134751773, Blast_Score=99, Evalue=2e-21,
Organism=Drosophila melanogaster, GI18859735, Length=379, Percent_Identity=28.2321899736148, Blast_Score=152, Evalue=4e-37,
Organism=Drosophila melanogaster, GI45551451, Length=470, Percent_Identity=26.3829787234043, Blast_Score=123, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24641770, Length=470, Percent_Identity=26.3829787234043, Blast_Score=123, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24641760, Length=470, Percent_Identity=26.3829787234043, Blast_Score=123, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24641768, Length=470, Percent_Identity=26.3829787234043, Blast_Score=123, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24641766, Length=470, Percent_Identity=26.3829787234043, Blast_Score=123, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24641764, Length=470, Percent_Identity=26.3829787234043, Blast_Score=123, Evalue=2e-28,
Organism=Drosophila melanogaster, GI28573069, Length=168, Percent_Identity=29.1666666666667, Blast_Score=85, Evalue=7e-17,
Organism=Drosophila melanogaster, GI24646114, Length=168, Percent_Identity=29.1666666666667, Blast_Score=85, Evalue=7e-17,
Organism=Drosophila melanogaster, GI28573067, Length=168, Percent_Identity=29.1666666666667, Blast_Score=85, Evalue=7e-17,
Organism=Drosophila melanogaster, GI28573065, Length=168, Percent_Identity=29.1666666666667, Blast_Score=85, Evalue=7e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.1

Molecular weight: Translated: 44804; Mature: 44804

Theoretical pI: Translated: 6.60; Mature: 6.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQVSKSNKLANVCYDIRGPVLKHAKRLEEEGHRILKLNIGNPAPFGFEAPEEILQDVIRN
CCCCCCCCHHHHHHHHCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHHH
LPTAQGYSDSKGLFSARKAIMQYYQQKQVEGIGIEDIYLGNGVSELIVMSMQALLNNGDE
CCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHCCCCE
VLIPAPDYPLWTAAVSLAGGKPVHYLCDEQANWWPDLADIKAKITPNTKALVLINPNNPT
EEEECCCCCHHHHHHHHCCCCCEEEEECCCCCCCCCHHHCEEEECCCCEEEEEECCCCCC
GAVYPKEVLEGMVELARQHKLVLFSDEIYDKILYDGAVHISTASLAPDVLCLTFNGLSKS
CCCCHHHHHHHHHHHHHHCCEEEECHHHHHHHHHCCEEEEEEHHCCCCEEEEEECCCCCC
YRVAGFRSGWVAISGPKHKAQSYIEGLDILANMRLCANVPSQHAIQTALGGYQSINDLVL
EEEEEECCCEEEECCCHHHHHHHHHHHHHHHCCHHHHCCCHHHHHHHHHCCHHCCCCCCC
PPGRLLEQRNRTWELLNDIPGISCVKPMGALYAFPRIDPKICPIHNDEKFVLDLLLSEKL
CCHHHHHHCCCHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCE
LIVQGTAFNWPWPDHFRVVTLPRVDDLEQAIGRIGNFLKTYQQ
EEEECCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MQVSKSNKLANVCYDIRGPVLKHAKRLEEEGHRILKLNIGNPAPFGFEAPEEILQDVIRN
CCCCCCCCHHHHHHHHCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHHH
LPTAQGYSDSKGLFSARKAIMQYYQQKQVEGIGIEDIYLGNGVSELIVMSMQALLNNGDE
CCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHCCCCE
VLIPAPDYPLWTAAVSLAGGKPVHYLCDEQANWWPDLADIKAKITPNTKALVLINPNNPT
EEEECCCCCHHHHHHHHCCCCCEEEEECCCCCCCCCHHHCEEEECCCCEEEEEECCCCCC
GAVYPKEVLEGMVELARQHKLVLFSDEIYDKILYDGAVHISTASLAPDVLCLTFNGLSKS
CCCCHHHHHHHHHHHHHHCCEEEECHHHHHHHHHCCEEEEEEHHCCCCEEEEEECCCCCC
YRVAGFRSGWVAISGPKHKAQSYIEGLDILANMRLCANVPSQHAIQTALGGYQSINDLVL
EEEEEECCCEEEECCCHHHHHHHHHHHHHHHCCHHHHCCCHHHHHHHHHCCHHCCCCCCC
PPGRLLEQRNRTWELLNDIPGISCVKPMGALYAFPRIDPKICPIHNDEKFVLDLLLSEKL
CCHHHHHHCCCHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCE
LIVQGTAFNWPWPDHFRVVTLPRVDDLEQAIGRIGNFLKTYQQ
EEEECCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-aspartate; 2-oxoglutarate

Specific reaction: L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]