Click here to switch to the map view.

The map label for this gene is trkH [H]

Identifier: 146282798

GI number: 146282798

Start: 2682206

End: 2683738

Strand: Direct

Name: trkH [H]

Synonym: PST_2457

Alternate gene names: 146282798

Gene position: 2682206-2683738 (Clockwise)

Preceding gene: 146282795

Following gene: 146282801

Centisome position: 58.72

GC content: 64.06

Gene sequence:

>1533_bases
ATGAACCGCCGAGCGGTTTACTGCCACCGCGACGCGAGTAGAATGTCGGCCCCTCTTTCACCCGTGCCGAGCACCTTCTA
CATGGCCCTGCCGACCCTGCGCATCATCGGTTTCATCCTCGGCATTTTCCTCATCACCCTTGCCGTCAGCATGATCATCC
CGATGCTGACACTGCTGGCCTACGAGCGCACCGACGACCTGCAGGCCTTCATCTGGGGCAGCCTGATCACCTTCTCCTGC
GGCTTCGCCCTGGTCGCCCCGGGCAAGCCGGCCAATACCCACCTGCGCCCGCGCGACATGTACTTCCTGACGACCATCAG
CTGGGTGGTGGTCTGCTGCTTCGCCGCGCTGCCGCTGATGCTGATCCAGCACATCAGCTATTCGGATGCCTTCTTCGAGA
CCATGTCGGGCATCACCACCACCGGCGCGACGGTACTCTCGGGCCTGGACAGCGCCTCCCCCGGCCTGCTGATGTGGCGG
TCACTGCTGCACTGGCTGGGCGGCATCGGCTTCATCGGCATGGCCATCGCGATCCTGCCGCTGCTGCGCGTCGGCGGCAT
GCGGCTGTTCCAGACCGAATCCTCGGACTGGTCGGAAAAGGTCATGCCGCGCTCGCACGTGGCCGGGCAGTATCTGCTGG
TGATCTACGTGACCTTCACCATCGCGGCCTTCATCGCCTTTCTGCTGACCGGCATGGGCGCCTTCGACGCCATCAACCAT
GCCATGTCCACCGTCGCCACCGGCGGCTTCTCCACCTCGGACGCCTCGATGGGCAAGTTCGGCCCCTCGGCCCACTGGGT
CGCGGTGTTCTTCATGATCGTCGGCAGCCTGCCGTTCACGCTGTACGTGATGACCCTGCGCGGCCACCGCACTGCGCTGT
TCAGGGATCAGCAGGTGCGTGGCTTCGTGCTCATGCTGGCCATCACCAGCGTGCTGTTCAGCGGCTGGTACTGGCTAAAC
AACGATGTACCGGCGCTGGATGCACTGCGCATCGTCACTTTCAGCGTGGTATCGGTGGTCACCACAACCGGCTTCGCGGT
GGACGACTACACCCAGTGGGGCGGCTTCGCGGTCATGGCGTTCTTCTACCTGACCTTTATCGGCGGCTGCTCGGGCTCGA
CCTCAGGCGGCCTGAAGATGTTCCGCTTCCAGGTGGCCTATTCGCTGCTGCGCGCCAACTTCAAGCAGCTGATCCATCCC
CGCGCGGTGATCCGTCAGCAGTACAACGGCCACAACCTCGACGAGGAAATCGTCCGTTCGATCCTCACCTTCTCGTTCTT
CATCACGATGACCATCGGTGTGCTGGCGCTGTGTCTGGCACTGCTGGGCCTGGACCCGATCACCGCACTGACCGGCGCGG
CGACCGCCGTGTGCAACGTCGGCCCCGGGCTGGGCGAGATCATCGGGCCGGCCGGCAACTTCTCCACATTGCCGGACACC
GCCAAGTGGCTGCTGTCGATCGGCATGCTGCTCGGCCGCCTGGAAATCATCACCGTGCTGGTGCTACTGACCCCGGCCTT
CTGGCGTCACTGA

Upstream 100 bases:

>100_bases
AACACCCAGAGACCGGAATGGGCCGGCGCCCGGGCGGCTATTCTATTCATGCCGATGGGCTTGGGAAGGGGCCGGGGCCA
CGCCGCGAAAACATTTTTCA

Downstream 100 bases:

>100_bases
TCAGGCCGCGGCGCCGGAGCCGCGCTTGAACAAGCGGCCACCCAGCGTCACCAGCCCCAGCACGACAGCGCCGACGAGGA
TGCCGAATGCGGCATCCAGC

Product: potassium uptake protein TrkH

Products: Proton [Cytoplasm]; K (I) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 510; Mature: 510

Protein sequence:

>510_residues
MNRRAVYCHRDASRMSAPLSPVPSTFYMALPTLRIIGFILGIFLITLAVSMIIPMLTLLAYERTDDLQAFIWGSLITFSC
GFALVAPGKPANTHLRPRDMYFLTTISWVVVCCFAALPLMLIQHISYSDAFFETMSGITTTGATVLSGLDSASPGLLMWR
SLLHWLGGIGFIGMAIAILPLLRVGGMRLFQTESSDWSEKVMPRSHVAGQYLLVIYVTFTIAAFIAFLLTGMGAFDAINH
AMSTVATGGFSTSDASMGKFGPSAHWVAVFFMIVGSLPFTLYVMTLRGHRTALFRDQQVRGFVLMLAITSVLFSGWYWLN
NDVPALDALRIVTFSVVSVVTTTGFAVDDYTQWGGFAVMAFFYLTFIGGCSGSTSGGLKMFRFQVAYSLLRANFKQLIHP
RAVIRQQYNGHNLDEEIVRSILTFSFFITMTIGVLALCLALLGLDPITALTGAATAVCNVGPGLGEIIGPAGNFSTLPDT
AKWLLSIGMLLGRLEIITVLVLLTPAFWRH

Sequences:

>Translated_510_residues
MNRRAVYCHRDASRMSAPLSPVPSTFYMALPTLRIIGFILGIFLITLAVSMIIPMLTLLAYERTDDLQAFIWGSLITFSC
GFALVAPGKPANTHLRPRDMYFLTTISWVVVCCFAALPLMLIQHISYSDAFFETMSGITTTGATVLSGLDSASPGLLMWR
SLLHWLGGIGFIGMAIAILPLLRVGGMRLFQTESSDWSEKVMPRSHVAGQYLLVIYVTFTIAAFIAFLLTGMGAFDAINH
AMSTVATGGFSTSDASMGKFGPSAHWVAVFFMIVGSLPFTLYVMTLRGHRTALFRDQQVRGFVLMLAITSVLFSGWYWLN
NDVPALDALRIVTFSVVSVVTTTGFAVDDYTQWGGFAVMAFFYLTFIGGCSGSTSGGLKMFRFQVAYSLLRANFKQLIHP
RAVIRQQYNGHNLDEEIVRSILTFSFFITMTIGVLALCLALLGLDPITALTGAATAVCNVGPGLGEIIGPAGNFSTLPDT
AKWLLSIGMLLGRLEIITVLVLLTPAFWRH
>Mature_510_residues
MNRRAVYCHRDASRMSAPLSPVPSTFYMALPTLRIIGFILGIFLITLAVSMIIPMLTLLAYERTDDLQAFIWGSLITFSC
GFALVAPGKPANTHLRPRDMYFLTTISWVVVCCFAALPLMLIQHISYSDAFFETMSGITTTGATVLSGLDSASPGLLMWR
SLLHWLGGIGFIGMAIAILPLLRVGGMRLFQTESSDWSEKVMPRSHVAGQYLLVIYVTFTIAAFIAFLLTGMGAFDAINH
AMSTVATGGFSTSDASMGKFGPSAHWVAVFFMIVGSLPFTLYVMTLRGHRTALFRDQQVRGFVLMLAITSVLFSGWYWLN
NDVPALDALRIVTFSVVSVVTTTGFAVDDYTQWGGFAVMAFFYLTFIGGCSGSTSGGLKMFRFQVAYSLLRANFKQLIHP
RAVIRQQYNGHNLDEEIVRSILTFSFFITMTIGVLALCLALLGLDPITALTGAATAVCNVGPGLGEIIGPAGNFSTLPDT
AKWLLSIGMLLGRLEIITVLVLLTPAFWRH

Specific function: Low-affinity potassium transport system. Interacts with trk system potassium uptake protein trkA and requires trkE for transport activity [H]

COG id: COG0168

COG function: function code P; Trk-type K+ transport systems, membrane components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trkH potassium transport family [H]

Homologues:

Organism=Escherichia coli, GI48994987, Length=484, Percent_Identity=35.9504132231405, Blast_Score=236, Evalue=2e-63,
Organism=Escherichia coli, GI1787626, Length=489, Percent_Identity=33.1288343558282, Blast_Score=232, Evalue=4e-62,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003445
- InterPro:   IPR004772 [H]

Pfam domain/function: PF02386 TrkH [H]

EC number: NA

Molecular weight: Translated: 55694; Mature: 55694

Theoretical pI: Translated: 8.64; Mature: 8.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRRAVYCHRDASRMSAPLSPVPSTFYMALPTLRIIGFILGIFLITLAVSMIIPMLTLLA
CCCCEEEEECCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YERTDDLQAFIWGSLITFSCGFALVAPGKPANTHLRPRDMYFLTTISWVVVCCFAALPLM
HHCCCHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
LIQHISYSDAFFETMSGITTTGATVLSGLDSASPGLLMWRSLLHWLGGIGFIGMAIAILP
HHHHCCCHHHHHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LLRVGGMRLFQTESSDWSEKVMPRSHVAGQYLLVIYVTFTIAAFIAFLLTGMGAFDAINH
HHHHCCCEEEECCCCCHHHHCCCHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
AMSTVATGGFSTSDASMGKFGPSAHWVAVFFMIVGSLPFTLYVMTLRGHRTALFRDQQVR
HHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHCCHHHH
GFVLMLAITSVLFSGWYWLNNDVPALDALRIVTFSVVSVVTTTGFAVDDYTQWGGFAVMA
HHHHHHHHHHHHHHCCEEECCCCCHHHHHHHHHHHHHHHHHHCCCEECCCHHHHHHHHHH
FFYLTFIGGCSGSTSGGLKMFRFQVAYSLLRANFKQLIHPRAVIRQQYNGHNLDEEIVRS
HHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCCHHHHHH
ILTFSFFITMTIGVLALCLALLGLDPITALTGAATAVCNVGPGLGEIIGPAGNFSTLPDT
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHCCCCCCCCCCCHH
AKWLLSIGMLLGRLEIITVLVLLTPAFWRH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNRRAVYCHRDASRMSAPLSPVPSTFYMALPTLRIIGFILGIFLITLAVSMIIPMLTLLA
CCCCEEEEECCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YERTDDLQAFIWGSLITFSCGFALVAPGKPANTHLRPRDMYFLTTISWVVVCCFAALPLM
HHCCCHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
LIQHISYSDAFFETMSGITTTGATVLSGLDSASPGLLMWRSLLHWLGGIGFIGMAIAILP
HHHHCCCHHHHHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LLRVGGMRLFQTESSDWSEKVMPRSHVAGQYLLVIYVTFTIAAFIAFLLTGMGAFDAINH
HHHHCCCEEEECCCCCHHHHCCCHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
AMSTVATGGFSTSDASMGKFGPSAHWVAVFFMIVGSLPFTLYVMTLRGHRTALFRDQQVR
HHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHCCHHHH
GFVLMLAITSVLFSGWYWLNNDVPALDALRIVTFSVVSVVTTTGFAVDDYTQWGGFAVMA
HHHHHHHHHHHHHHCCEEECCCCCHHHHHHHHHHHHHHHHHHCCCEECCCHHHHHHHHHH
FFYLTFIGGCSGSTSGGLKMFRFQVAYSLLRANFKQLIHPRAVIRQQYNGHNLDEEIVRS
HHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCCHHHHHH
ILTFSFFITMTIGVLALCLALLGLDPITALTGAATAVCNVGPGLGEIIGPAGNFSTLPDT
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHCCCCCCCCCCCHH
AKWLLSIGMLLGRLEIITVLVLLTPAFWRH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; K (I) [Periplasm] [C]

Specific reaction: Proton [Periplasm] + K (I) [Periplasm] = Proton [Cytoplasm] + K (I) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]