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The map label for this gene is pfeS [H]

Identifier: 146282795

GI number: 146282795

Start: 2679719

End: 2681077

Strand: Direct

Name: pfeS [H]

Synonym: PST_2454

Alternate gene names: 146282795

Gene position: 2679719-2681077 (Clockwise)

Preceding gene: 146282794

Following gene: 146282798

Centisome position: 58.67

GC content: 68.8

Gene sequence:

>1359_bases
GTGCGATCACTGTTCTGGCGCATACTCGCAACCTTCTGGCTGGCCATTGCCCTGGTCGCCGGCCTGGCGATGCTGCTCGG
CCATGCACTGAACCAGGATGCCTGGATTCTCGGTCGGCATCCCGCCTTGCAGGGCCTGGCCGAGACCTGGACCGAAGTCT
ACGAGCGCCAGGGCCCGCTGGCCGCTCAGCGGCTGCTCGAACAGCACCGCCATCGTGCACGGGTCGATGTACAGGTCCTG
GCGGAAAACGGCCAGCCGATCATCCGCGGTACCTTCCCCGCCCGCGCTGCCGCCTTCGAGGCGCGCCATCAGGATCGCGA
GCGTCCACTGCCCTGGCGACGCCTGACCGCCGACTACACCAGCCCGACCACCGGCGAAACCTACCTGTTCATCTACCGTA
TTCCGCATCCCGAACTGCAGGCCTGGCACCGCGGCAGCCTGGCCTGGCCGCTGAGTGCGCTGGGCATCGCTCTGGTGGTG
CTGACCGGCTTCAGCCTGCTGCTGACGCTCTCCATCACCCGACCGCTGGATCGCCTGCGCCGTGCCGTGCACGACCTCGG
CCGGACGACCTATCAGCAGCAGTCGCTGGCGCGCCTGGCGACCCGCCGCGACGAGCTCGGCGTGCTGGCCAGCGATTTCA
ATCGCATGGGTGCGCGCTTGCAGGCACTGATCGGCAGCCAGCGACAGTTGCTGCGCGACGTGTCCCACGAATTGCGCTCG
CCGCTGGCGCGACTGCGCATTGCCCTGGGCCTGGCCGAGCGCGCCACGCCCACCGAACGCGAGGTGATCTGGCCACGGCT
GGCCAAGGAATGCGACCGCCTGGAGGCGTTGATCAGCGAGATTCTGGAACTCTCGCGGCTGGATGCCGAGCCCGGCGCGG
CAATCGACGTCGATCTGCCCGATATGTTCGAACAGCTGAAGGACAACGCCCGTATCGTCGCCCCCACGCAACGTATCGAC
AGTCGCGTCGAACCCGGCATCCGCTACACGGGCTGGCCGGATATGCTCGAGCGTGCGCTGGACAATCTGCTGCGCAATGC
CCTGCGCTTCAATCCAGAAGGGGTGCCGGTGGAGCTGCGCGCCCAGCGCGACGGCCAGGACCTGGTGATCAGCGTTCGCG
ACCATGGCCCCGGCGTGGCCGACGAGCACTTGCCCCAGCTCAGCGAGCCTTTCTTCCGAGCCCCGGGCCAGACCGCGGCC
GGGCATGGCCTGGGGCTGGCCATCGCCCGACGCGCCGCCGAGCGCCACGGCGGCCAGCTGCAACTGGCCAATCACCCCGA
CGGCGGCTTCGTCGCCCGCCTGCGTCTGCCGCTGGCCGGCCCGGCGAGCAGAACCTCAGACGATCTGGCGTCTCACTGA

Upstream 100 bases:

>100_bases
GAAGAACTGATCCGGCGGTCCATCTGATACCCCGCCCGGCAGCGTCCGCCCGTCATGTGATGGGCGAAGCGTGCCGGGCT
TTTTGCCGTGGAGAGACCCG

Downstream 100 bases:

>100_bases
GCGTTCCAACGCTGGACGAAGTCCTTGGGCTCCAGAACCGGCGCGCTGCGTACGCGGCCTTCCGGCGTACCCATATAGAG
AAAGCCCAGCAGGCGCTCCT

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 452; Mature: 452

Protein sequence:

>452_residues
MRSLFWRILATFWLAIALVAGLAMLLGHALNQDAWILGRHPALQGLAETWTEVYERQGPLAAQRLLEQHRHRARVDVQVL
AENGQPIIRGTFPARAAAFEARHQDRERPLPWRRLTADYTSPTTGETYLFIYRIPHPELQAWHRGSLAWPLSALGIALVV
LTGFSLLLTLSITRPLDRLRRAVHDLGRTTYQQQSLARLATRRDELGVLASDFNRMGARLQALIGSQRQLLRDVSHELRS
PLARLRIALGLAERATPTEREVIWPRLAKECDRLEALISEILELSRLDAEPGAAIDVDLPDMFEQLKDNARIVAPTQRID
SRVEPGIRYTGWPDMLERALDNLLRNALRFNPEGVPVELRAQRDGQDLVISVRDHGPGVADEHLPQLSEPFFRAPGQTAA
GHGLGLAIARRAAERHGGQLQLANHPDGGFVARLRLPLAGPASRTSDDLASH

Sequences:

>Translated_452_residues
MRSLFWRILATFWLAIALVAGLAMLLGHALNQDAWILGRHPALQGLAETWTEVYERQGPLAAQRLLEQHRHRARVDVQVL
AENGQPIIRGTFPARAAAFEARHQDRERPLPWRRLTADYTSPTTGETYLFIYRIPHPELQAWHRGSLAWPLSALGIALVV
LTGFSLLLTLSITRPLDRLRRAVHDLGRTTYQQQSLARLATRRDELGVLASDFNRMGARLQALIGSQRQLLRDVSHELRS
PLARLRIALGLAERATPTEREVIWPRLAKECDRLEALISEILELSRLDAEPGAAIDVDLPDMFEQLKDNARIVAPTQRID
SRVEPGIRYTGWPDMLERALDNLLRNALRFNPEGVPVELRAQRDGQDLVISVRDHGPGVADEHLPQLSEPFFRAPGQTAA
GHGLGLAIARRAAERHGGQLQLANHPDGGFVARLRLPLAGPASRTSDDLASH
>Mature_452_residues
MRSLFWRILATFWLAIALVAGLAMLLGHALNQDAWILGRHPALQGLAETWTEVYERQGPLAAQRLLEQHRHRARVDVQVL
AENGQPIIRGTFPARAAAFEARHQDRERPLPWRRLTADYTSPTTGETYLFIYRIPHPELQAWHRGSLAWPLSALGIALVV
LTGFSLLLTLSITRPLDRLRRAVHDLGRTTYQQQSLARLATRRDELGVLASDFNRMGARLQALIGSQRQLLRDVSHELRS
PLARLRIALGLAERATPTEREVIWPRLAKECDRLEALISEILELSRLDAEPGAAIDVDLPDMFEQLKDNARIVAPTQRID
SRVEPGIRYTGWPDMLERALDNLLRNALRFNPEGVPVELRAQRDGQDLVISVRDHGPGVADEHLPQLSEPFFRAPGQTAA
GHGLGLAIARRAAERHGGQLQLANHPDGGFVARLRLPLAGPASRTSDDLASH

Specific function: Member of the two-component regulatory system pfeR/pfeS. May activate pfeR by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1790346, Length=291, Percent_Identity=31.2714776632302, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1789403, Length=233, Percent_Identity=34.7639484978541, Blast_Score=118, Evalue=8e-28,
Organism=Escherichia coli, GI1786600, Length=228, Percent_Identity=32.8947368421053, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI1787894, Length=326, Percent_Identity=31.5950920245399, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1788393, Length=271, Percent_Identity=30.2583025830258, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1790861, Length=289, Percent_Identity=30.7958477508651, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1786783, Length=240, Percent_Identity=29.1666666666667, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1789808, Length=317, Percent_Identity=28.0757097791798, Blast_Score=89, Evalue=8e-19,
Organism=Escherichia coli, GI87082128, Length=293, Percent_Identity=27.6450511945392, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1790551, Length=283, Percent_Identity=28.9752650176678, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI1790436, Length=216, Percent_Identity=31.9444444444444, Blast_Score=85, Evalue=9e-18,
Organism=Escherichia coli, GI87081816, Length=280, Percent_Identity=28.9285714285714, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI145693157, Length=239, Percent_Identity=27.6150627615063, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1786912, Length=231, Percent_Identity=27.7056277056277, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1788279, Length=315, Percent_Identity=24.1269841269841, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1790300, Length=221, Percent_Identity=27.6018099547511, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1789149, Length=220, Percent_Identity=25.9090909090909, Blast_Score=63, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 50527; Mature: 50527

Theoretical pI: Translated: 9.75; Mature: 9.75

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSLFWRILATFWLAIALVAGLAMLLGHALNQDAWILGRHPALQGLAETWTEVYERQGPL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHHHCCCCH
AAQRLLEQHRHRARVDVQVLAENGQPIIRGTFPARAAAFEARHQDRERPLPWRRLTADYT
HHHHHHHHHHHHHHCEEEEEECCCCEEEEECCCHHHHHHHHHHHHCCCCCCHHHHCCCCC
SPTTGETYLFIYRIPHPELQAWHRGSLAWPLSALGIALVVLTGFSLLLTLSITRPLDRLR
CCCCCCEEEEEEECCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RAVHDLGRTTYQQQSLARLATRRDELGVLASDFNRMGARLQALIGSQRQLLRDVSHELRS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PLARLRIALGLAERATPTEREVIWPRLAKECDRLEALISEILELSRLDAEPGAAIDVDLP
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCH
DMFEQLKDNARIVAPTQRIDSRVEPGIRYTGWPDMLERALDNLLRNALRFNPEGVPVELR
HHHHHHHCCCEEEECHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEE
AQRDGQDLVISVRDHGPGVADEHLPQLSEPFFRAPGQTAAGHGLGLAIARRAAERHGGQL
ECCCCCEEEEEEECCCCCCCHHHCHHHCCHHHCCCCCCCCCCCHHHHHHHHHHHHCCCEE
QLANHPDGGFVARLRLPLAGPASRTSDDLASH
EECCCCCCCEEEEEECCCCCCCCCCCHHHCCC
>Mature Secondary Structure
MRSLFWRILATFWLAIALVAGLAMLLGHALNQDAWILGRHPALQGLAETWTEVYERQGPL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHHHCCCCH
AAQRLLEQHRHRARVDVQVLAENGQPIIRGTFPARAAAFEARHQDRERPLPWRRLTADYT
HHHHHHHHHHHHHHCEEEEEECCCCEEEEECCCHHHHHHHHHHHHCCCCCCHHHHCCCCC
SPTTGETYLFIYRIPHPELQAWHRGSLAWPLSALGIALVVLTGFSLLLTLSITRPLDRLR
CCCCCCEEEEEEECCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RAVHDLGRTTYQQQSLARLATRRDELGVLASDFNRMGARLQALIGSQRQLLRDVSHELRS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PLARLRIALGLAERATPTEREVIWPRLAKECDRLEALISEILELSRLDAEPGAAIDVDLP
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCH
DMFEQLKDNARIVAPTQRIDSRVEPGIRYTGWPDMLERALDNLLRNALRFNPEGVPVELR
HHHHHHHCCCEEEECHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEE
AQRDGQDLVISVRDHGPGVADEHLPQLSEPFFRAPGQTAAGHGLGLAIARRAAERHGGQL
ECCCCCEEEEEEECCCCCCCHHHCHHHCCHHHCCCCCCCCCCCHHHHHHHHHHHHCCCEE
QLANHPDGGFVARLRLPLAGPASRTSDDLASH
EECCCCCCCEEEEEECCCCCCCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8361354; 10984043 [H]