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The map label for this gene is exaA [H]

Identifier: 146282619

GI number: 146282619

Start: 2477917

End: 2480115

Strand: Direct

Name: exaA [H]

Synonym: PST_2270

Alternate gene names: 146282619

Gene position: 2477917-2480115 (Clockwise)

Preceding gene: 146282614

Following gene: 146282620

Centisome position: 54.25

GC content: 63.48

Gene sequence:

>2199_bases
ATGATCTTGTTGTTCATGACTACCACCCTCTATTCGAGAACCTGTGCAAGGCAGCCCCAATCGGAGCGCATGGTGGTCAT
GTTGGCCGCGCGGACGGATCGGCAGAATCCTGCTTTGGATGCCTGCATCTCCTCCCTTGGTACTGGGTTTTGCTACCACC
TTCGGCACCCCACCGGTAGCAAGGCCAAATCATCGGCGGCCGGGAAGGAATCCCGGTGTTGGCGGGAGCTTTTCCGTGTC
GGTGCGCGCGCCGCGCTTCCAATAATCGAATCGCCTGGCCAGCCGGATGTGGCGGCCTCGTTCGAATCGACCAAGGGAAT
CGCAACCATGAAAACAAGATCGCACCCCGGCGCACCCCGCCCGCTCGCACTTGCCGTGCAATGCCTGGCTCTGGCCGGCA
GCCTTGCCATGGCGGGCGCCGTGCACGCCAAACCGGTCAGCTGGGAAGACATCGCCAATGACCATGTCACCACCAGCAAC
GTGCTGCAGTACGGCATGGGCACCAATGCACAGCGCTGGAGCCCTCTGGCGCAGGTCAACGAGAGCAATGTGTTCAAGCT
GACCCCGGCCTGGTCGTTCTCCTTCGGCGACGAGAAGCAGCGCGGCCAGGAATCCCAGGCCATCGTTCACGACGGCGTGA
TCTACGTTACCGGCTCCTATTCGCGGGTGTTCGCCCTCGATGCGAAGACCGGAAAGCGCCTGTGGAGCTATGCCCATCGC
CTGCCCGACGACATCCGCCCGTGCTGCGACGTGGTCAACCGCGGCGCCGCCATCTATGGCGACAAGATCTACTTCGGCAC
CCTCGATGCCCGTGTCGTGGCACTGAACAAGGACACCGGCAAGGTCGTCTGGAACAAGAAGTTCGGCGACCATGGCGCCG
GTTACACGATGACCGGCGCACCGACCCTGGTAAAGGACGGCAAGACCGGCAAGGTCCTGCTGATCCACGGCAGCTCCGGT
GACGAGTTCGGTATCGTCGGCAAGCTGTTCGCCCGCGACCCGGATACCGGTGAGGAAATCTGGATGCGCCCGTTCGTCGA
AGGCCACATGGGCCGCCTCAATGGCAAGGACAGCACCCCCACCGGCGACATCAAGGCGCCGTCCTGGCCGGACGATCCCA
ACCACCCCACCGGCAAGAAGGAAGCCTGGAGCCAGGGCGGCGGCGCTCCATGGCAGAGCGCCAGCTTCGATCCGGAGACC
AACACCATCATCGTCGGTGCGGGCAACCCGGCACCCTGGAACGGCTGGGAGCGCACCAGCGACGGTGGCAATCCGAACGA
CTACGACAGCCTCTACACCTCAGGGCAGGTCGGCGTCGATCCGAGCACCGGCGAGGTGAAGTGGTTCTACCAGCACACCC
CGAACGATGCCTGGGACTTCTCCGGCAACAACGAGCTGGTGCTGTTCGACTACAAGGACAAGGCCGGCAAGACCGTCAAG
GCCACCGCCCATGCCGACCGCAACGGCTTCTTCTATGTGGTGGACCGCAAGGACGGCAAGCTGCAGAACGCCTTCCCCTT
CGTGGACGGCATCACCTGGGCCAGCCATATCGATCTGAAAACCGGGCGACCGGTCGAGAACGAAGGCCAGCGCCCACCCA
AACCGGAGCCGGGCGAGAAGCACGGCAAGTCGGTGGAAGTCTCGCCACCCTTCCTCGGTGGCAAGAACTGGAACCCCATG
GCCTACAGCCAGGACACCGGCCTGTTCTACGTGCCGGCCAACCACTGGAAGGAGGACTACTGGACCGAGGAAGTCAGCTA
CAAGAAAGGCTCCGCCTACCTGGGCCAGGGTTTCCGCATCAAGCGCATGTACGACGACCACGTCGGCATCCTGCGCGCCA
TGAATCCCGCCACCGGCAAGATGGAATGGGAACACAAGGAAAAGCTGCCGCTGTGGGCCGGCGTGCTGGCGACCAAGGGC
AACCTGGTCTTCACCGGCACCAGCGACGGCTACATCAAGGCCTTCAACGCCAAAACCGGTGACGAGCTGTGGAAGTTCCA
GACCGGCAGCGGCGTGATTTCCCCGCCCATCACCTGGGAACAGGACGGCGAGCAGTACATCGGCGTAACGGTCGGCTATG
GCGGCGCCGTGCCCCTGTGGGGCGGTGACATGGCCGTGCTGACCAAGCCGGTCGCCCAGGGCGGCTCGTTCTGGGTATTC
AAGCTGCCGGACTGGGAGAAGAAGACCGCCAAACGATGA

Upstream 100 bases:

>100_bases
CGGCAGGCCTTTGGTGTTGACAGCCTGTGGCGTCACGTCGCCATGGGCGAATACCAGTCCGGAAACCCCGAGGACACCCG
CTGCCAGCAGTGCGCGCAAA

Downstream 100 bases:

>100_bases
GTGGAGCCGTGCCCGCCCACGCGGGCACGTCCTCAAGCCCTCAAGGTACAGCGGTTCGCGCGGCATGCCTGGCCTCGCCG
GCTCCGGGTTGGCGCTCTCG

Product: quinoprotein alcohol dehydrogenase

Products: NA

Alternate protein names: QEDH [H]

Number of amino acids: Translated: 732; Mature: 732

Protein sequence:

>732_residues
MILLFMTTTLYSRTCARQPQSERMVVMLAARTDRQNPALDACISSLGTGFCYHLRHPTGSKAKSSAAGKESRCWRELFRV
GARAALPIIESPGQPDVAASFESTKGIATMKTRSHPGAPRPLALAVQCLALAGSLAMAGAVHAKPVSWEDIANDHVTTSN
VLQYGMGTNAQRWSPLAQVNESNVFKLTPAWSFSFGDEKQRGQESQAIVHDGVIYVTGSYSRVFALDAKTGKRLWSYAHR
LPDDIRPCCDVVNRGAAIYGDKIYFGTLDARVVALNKDTGKVVWNKKFGDHGAGYTMTGAPTLVKDGKTGKVLLIHGSSG
DEFGIVGKLFARDPDTGEEIWMRPFVEGHMGRLNGKDSTPTGDIKAPSWPDDPNHPTGKKEAWSQGGGAPWQSASFDPET
NTIIVGAGNPAPWNGWERTSDGGNPNDYDSLYTSGQVGVDPSTGEVKWFYQHTPNDAWDFSGNNELVLFDYKDKAGKTVK
ATAHADRNGFFYVVDRKDGKLQNAFPFVDGITWASHIDLKTGRPVENEGQRPPKPEPGEKHGKSVEVSPPFLGGKNWNPM
AYSQDTGLFYVPANHWKEDYWTEEVSYKKGSAYLGQGFRIKRMYDDHVGILRAMNPATGKMEWEHKEKLPLWAGVLATKG
NLVFTGTSDGYIKAFNAKTGDELWKFQTGSGVISPPITWEQDGEQYIGVTVGYGGAVPLWGGDMAVLTKPVAQGGSFWVF
KLPDWEKKTAKR

Sequences:

>Translated_732_residues
MILLFMTTTLYSRTCARQPQSERMVVMLAARTDRQNPALDACISSLGTGFCYHLRHPTGSKAKSSAAGKESRCWRELFRV
GARAALPIIESPGQPDVAASFESTKGIATMKTRSHPGAPRPLALAVQCLALAGSLAMAGAVHAKPVSWEDIANDHVTTSN
VLQYGMGTNAQRWSPLAQVNESNVFKLTPAWSFSFGDEKQRGQESQAIVHDGVIYVTGSYSRVFALDAKTGKRLWSYAHR
LPDDIRPCCDVVNRGAAIYGDKIYFGTLDARVVALNKDTGKVVWNKKFGDHGAGYTMTGAPTLVKDGKTGKVLLIHGSSG
DEFGIVGKLFARDPDTGEEIWMRPFVEGHMGRLNGKDSTPTGDIKAPSWPDDPNHPTGKKEAWSQGGGAPWQSASFDPET
NTIIVGAGNPAPWNGWERTSDGGNPNDYDSLYTSGQVGVDPSTGEVKWFYQHTPNDAWDFSGNNELVLFDYKDKAGKTVK
ATAHADRNGFFYVVDRKDGKLQNAFPFVDGITWASHIDLKTGRPVENEGQRPPKPEPGEKHGKSVEVSPPFLGGKNWNPM
AYSQDTGLFYVPANHWKEDYWTEEVSYKKGSAYLGQGFRIKRMYDDHVGILRAMNPATGKMEWEHKEKLPLWAGVLATKG
NLVFTGTSDGYIKAFNAKTGDELWKFQTGSGVISPPITWEQDGEQYIGVTVGYGGAVPLWGGDMAVLTKPVAQGGSFWVF
KLPDWEKKTAKR
>Mature_732_residues
MILLFMTTTLYSRTCARQPQSERMVVMLAARTDRQNPALDACISSLGTGFCYHLRHPTGSKAKSSAAGKESRCWRELFRV
GARAALPIIESPGQPDVAASFESTKGIATMKTRSHPGAPRPLALAVQCLALAGSLAMAGAVHAKPVSWEDIANDHVTTSN
VLQYGMGTNAQRWSPLAQVNESNVFKLTPAWSFSFGDEKQRGQESQAIVHDGVIYVTGSYSRVFALDAKTGKRLWSYAHR
LPDDIRPCCDVVNRGAAIYGDKIYFGTLDARVVALNKDTGKVVWNKKFGDHGAGYTMTGAPTLVKDGKTGKVLLIHGSSG
DEFGIVGKLFARDPDTGEEIWMRPFVEGHMGRLNGKDSTPTGDIKAPSWPDDPNHPTGKKEAWSQGGGAPWQSASFDPET
NTIIVGAGNPAPWNGWERTSDGGNPNDYDSLYTSGQVGVDPSTGEVKWFYQHTPNDAWDFSGNNELVLFDYKDKAGKTVK
ATAHADRNGFFYVVDRKDGKLQNAFPFVDGITWASHIDLKTGRPVENEGQRPPKPEPGEKHGKSVEVSPPFLGGKNWNPM
AYSQDTGLFYVPANHWKEDYWTEEVSYKKGSAYLGQGFRIKRMYDDHVGILRAMNPATGKMEWEHKEKLPLWAGVLATKG
NLVFTGTSDGYIKAFNAKTGDELWKFQTGSGVISPPITWEQDGEQYIGVTVGYGGAVPLWGGDMAVLTKPVAQGGSFWVF
KLPDWEKKTAKR

Specific function: Catalyzes the oxidation of primary alcohols except for methanol that is a very poor substrate [H]

COG id: COG4993

COG function: function code G; Glucose dehydrogenase

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial PQQ dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1786316, Length=374, Percent_Identity=25.1336898395722, Blast_Score=96, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019556
- InterPro:   IPR019551
- InterPro:   IPR018391
- InterPro:   IPR017512
- InterPro:   IPR002372
- InterPro:   IPR011047
- InterPro:   IPR001479 [H]

Pfam domain/function: PF01011 PQQ; PF10535 PQQ_C; PF10527 PQQ_N [H]

EC number: =1.1.2.8 [H]

Molecular weight: Translated: 80160; Mature: 80160

Theoretical pI: Translated: 8.41; Mature: 8.41

Prosite motif: PS00363 BACTERIAL_PQQ_1 ; PS00364 BACTERIAL_PQQ_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILLFMTTTLYSRTCARQPQSERMVVMLAARTDRQNPALDACISSLGTGFCYHLRHPTGS
CEEEEEEHHHHHHHHHCCCCCCCEEEEEEECCCCCCHHHHHHHHHHCCCEEEEEECCCCC
KAKSSAAGKESRCWRELFRVGARAALPIIESPGQPDVAASFESTKGIATMKTRSHPGAPR
CCHHCCCCCHHHHHHHHHHHCCCEECCEECCCCCCCCEECCCCCCCEEEEEECCCCCCCC
PLALAVQCLALAGSLAMAGAVHAKPVSWEDIANDHVTTSNVLQYGMGTNAQRWSPLAQVN
HHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCCHHHHHHHCCCCCCHHCCHHHHCC
ESNVFKLTPAWSFSFGDEKQRGQESQAIVHDGVIYVTGSYSRVFALDAKTGKRLWSYAHR
CCCEEEECCCEECCCCCHHHCCCCCCEEEECCEEEEECCCEEEEEEECCHHHHHHHHHHH
LPDDIRPCCDVVNRGAAIYGDKIYFGTLDARVVALNKDTGKVVWNKKFGDHGAGYTMTGA
CCHHHHHHHHHHHCCCEEECCEEEEEECCEEEEEEECCCCEEEEECCCCCCCCCEEECCC
PTLVKDGKTGKVLLIHGSSGDEFGIVGKLFARDPDTGEEIWMRPFVEGHMGRLNGKDSTP
CEEEECCCCCEEEEEECCCCCCCCEEEEEECCCCCCCHHHHHCCHHHCCCCCCCCCCCCC
TGDIKAPSWPDDPNHPTGKKEAWSQGGGAPWQSASFDPETNTIIVGAGNPAPWNGWERTS
CCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCC
DGGNPNDYDSLYTSGQVGVDPSTGEVKWFYQHTPNDAWDFSGNNELVLFDYKDKAGKTVK
CCCCCCCHHHHHCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCEEEEEECCCCCCCEEE
ATAHADRNGFFYVVDRKDGKLQNAFPFVDGITWASHIDLKTGRPVENEGQRPPKPEPGEK
EEEECCCCCEEEEEECCCCCCCCCCCCHHCCCEEEEEECCCCCCCCCCCCCCCCCCCCHH
HGKSVEVSPPFLGGKNWNPMAYSQDTGLFYVPANHWKEDYWTEEVSYKKGSAYLGQGFRI
CCCEEECCCCCCCCCCCCCCEEECCCCEEEECCCCCCCHHCCHHHCCCCCCEECCCCEEE
KRMYDDHVGILRAMNPATGKMEWEHKEKLPLWAGVLATKGNLVFTGTSDGYIKAFNAKTG
EEECCCCCEEEEECCCCCCCCCCCCCCCCCEEEEHEEECCCEEEECCCCCEEEEECCCCC
DELWKFQTGSGVISPPITWEQDGEQYIGVTVGYGGAVPLWGGDMAVLTKPVAQGGSFWVF
CHHEEEECCCCCCCCCCCCCCCCCEEEEEEEECCCCCEECCCCHHEEEHHHHCCCCEEEE
KLPDWEKKTAKR
ECCCCHHHHCCC
>Mature Secondary Structure
MILLFMTTTLYSRTCARQPQSERMVVMLAARTDRQNPALDACISSLGTGFCYHLRHPTGS
CEEEEEEHHHHHHHHHCCCCCCCEEEEEEECCCCCCHHHHHHHHHHCCCEEEEEECCCCC
KAKSSAAGKESRCWRELFRVGARAALPIIESPGQPDVAASFESTKGIATMKTRSHPGAPR
CCHHCCCCCHHHHHHHHHHHCCCEECCEECCCCCCCCEECCCCCCCEEEEEECCCCCCCC
PLALAVQCLALAGSLAMAGAVHAKPVSWEDIANDHVTTSNVLQYGMGTNAQRWSPLAQVN
HHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCCHHHHHHHCCCCCCHHCCHHHHCC
ESNVFKLTPAWSFSFGDEKQRGQESQAIVHDGVIYVTGSYSRVFALDAKTGKRLWSYAHR
CCCEEEECCCEECCCCCHHHCCCCCCEEEECCEEEEECCCEEEEEEECCHHHHHHHHHHH
LPDDIRPCCDVVNRGAAIYGDKIYFGTLDARVVALNKDTGKVVWNKKFGDHGAGYTMTGA
CCHHHHHHHHHHHCCCEEECCEEEEEECCEEEEEEECCCCEEEEECCCCCCCCCEEECCC
PTLVKDGKTGKVLLIHGSSGDEFGIVGKLFARDPDTGEEIWMRPFVEGHMGRLNGKDSTP
CEEEECCCCCEEEEEECCCCCCCCEEEEEECCCCCCCHHHHHCCHHHCCCCCCCCCCCCC
TGDIKAPSWPDDPNHPTGKKEAWSQGGGAPWQSASFDPETNTIIVGAGNPAPWNGWERTS
CCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCC
DGGNPNDYDSLYTSGQVGVDPSTGEVKWFYQHTPNDAWDFSGNNELVLFDYKDKAGKTVK
CCCCCCCHHHHHCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCEEEEEECCCCCCCEEE
ATAHADRNGFFYVVDRKDGKLQNAFPFVDGITWASHIDLKTGRPVENEGQRPPKPEPGEK
EEEECCCCCEEEEEECCCCCCCCCCCCHHCCCEEEEEECCCCCCCCCCCCCCCCCCCCHH
HGKSVEVSPPFLGGKNWNPMAYSQDTGLFYVPANHWKEDYWTEEVSYKKGSAYLGQGFRI
CCCEEECCCCCCCCCCCCCCEEECCCCEEEECCCCCCCHHCCHHHCCCCCCEECCCCEEE
KRMYDDHVGILRAMNPATGKMEWEHKEKLPLWAGVLATKGNLVFTGTSDGYIKAFNAKTG
EEECCCCCEEEEECCCCCCCCCCCCCCCCCEEEEHEEECCCEEEECCCCCEEEEECCCCC
DELWKFQTGSGVISPPITWEQDGEQYIGVTVGYGGAVPLWGGDMAVLTKPVAQGGSFWVF
CHHEEEECCCCCCCCCCCCCCCCCEEEEEEEECCCCCEECCCCHHEEEHHHHCCCCEEEE
KLPDWEKKTAKR
ECCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9826187; 10984043; 10075429; 10736230 [H]