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The map label for this gene is 146282580

Identifier: 146282580

GI number: 146282580

Start: 2436384

End: 2437694

Strand: Direct

Name: 146282580

Synonym: PST_2232

Alternate gene names: NA

Gene position: 2436384-2437694 (Clockwise)

Preceding gene: 146282579

Following gene: 146282581

Centisome position: 53.34

GC content: 65.45

Gene sequence:

>1311_bases
ATGCATACCCTGGAACAACTCGAACGTGGCGAACTGGCCGGCATCAGCCGCCTTGATCTTTCCGCCGGCCTTGACGCCTT
TCCCGACGCGATCTTCGGCCTCGCCGATACGCTGGAAGTGCTGAACCTCTCGGGCAACCAGCTCGACAGCCTGCCAGCCG
ACCTATCCCGGCTGCGCAAGCTGCGGATCCTGTTCTGCTCGGACAACCCGTTCACCGAGGTGCCGGAGTGTCTCGGCGAT
TGCCCGCAGCTGGAAATGGTCGGCTTCAAGGCCAATCGTATTCGTCATCTGCCTGCCGATTCCTTGCCGCCGGCTCTGCG
CTGGCTGATCCTTACCGATAACCAGCTGGAAAGCCTGCCCGACGAGATCGGCAACTGCCGAAGGCTGCAGAAGCTGATGC
TCGCCGGCAACCGGCTGACCAGCCTGCCGCCGTCCCTGTCCGAATGCACCCACCTAGAGTTGTTGCGCATCGCCGCCAAC
CGCCTGCAGCTGCTGCCAGACTGGCTGCTGACACTGCCGCGCCTGAGCTGGCTGGCCTTCGCCGGCAACCCCTTCAGCGA
CGCCAACGAGGCCGCGAGCCTTGCACGCCACTCGCTGCCGGCAATTGCTCGGGCGCAAGTCATCCTGCATGAACAGCTCG
GCCAAGGAGCCTCCGGCGTCATTCACCGAGCGCAATGGCAGGTGTCCGGCCAGGCGCCGCGACCCATGGCGGCGAAGCTG
TTCAAGGGACACGTCACCAGCGACGGCCTGCCGCATAGCGAAATGGCCGCGTGCGTGGCGGCTGGCCGTCACGCCAACCT
GATCGACGTCGCCGGCCCACTTGCCGACCACGCAGAGCTGACGCCCGGTCTGCTGATGGATCTCGTCGACCCTGGCTTCC
AACCCCTGGCCGGGCCACCCTCGCTGGCCAGCTGCACGCGCGACAGCTACGGTGCCGAGCAGCGTTTCAGCCTCGAACAG
GTCCTGCGCATCGCCAGCGGCGTCGCGTCCGCCGTTGCTCACCTGCACCGCCGCGGCATCCTGCATGGCGACCTCTATGC
CCACAACCTGCTGGTTGATCCAAGTGGCGCCTGCCTGCTCAGCGATTTCGGCGCGGCCTCCTTCTTCGAGCCCGACAGCG
CAGCCGGACAGCGCCTCAAGCGCATCGAAGCCCGCGCTTTCGGTTGCCTGCTGGAAGAATTGCTGCAACGCTGCCCGGAC
ACCGATCCACGTCAGCATGTCCTGCTGGATCTGCAACGACATTGCCTGAACGACAACATCGAGCAGCGACCGGACTTCGA
CCGTCTGCATAGCCTTCTCGCCGCGCTCTGA

Upstream 100 bases:

>100_bases
CCGCGCTGATCGGGCCTGAACCCACCTCGCCAACGGCTGTCGGAGCGCTGTAGCAGACGCCGTTTCGGTGTTCATCTCAG
CAAGGAAAGCGCAACACCGC

Downstream 100 bases:

>100_bases
CGCGCATTACCGGAGCGATTACACAGCCATGACCTCACCCGAAGCGGACGAGCCGCGCTCGCCCTATCCCAAGCCCTACG
CCGACACTCCGCTGGACCAG

Product: protein kinase, putative

Products: NA

Alternate protein names: Protein Kinase; Leucine-Rich Repeat-Containing Protein; Cytoplasmic Membrane Protein; Leucine-Rich Repeat Protein; Leucine-Rich Repeat-Containing Protein Kinase; Ras Family; Miro-Like Protein; Kinase; Phosphoprotein Phosphatase; Serine/Threonine-Protein Kinase-Like Domain Protein; Miro Domain Protein; Miro Domain-Containing Protein; Serine/Threonine-Protein Kinase-Like Domain; Protein Kinase Domain-Containing Protein; Leucine Rich Repeat Domain Protein; Outermembrane Protein; Protein KinaseLeucine-Rich Repeat Protein; Lipoprotein

Number of amino acids: Translated: 436; Mature: 436

Protein sequence:

>436_residues
MHTLEQLERGELAGISRLDLSAGLDAFPDAIFGLADTLEVLNLSGNQLDSLPADLSRLRKLRILFCSDNPFTEVPECLGD
CPQLEMVGFKANRIRHLPADSLPPALRWLILTDNQLESLPDEIGNCRRLQKLMLAGNRLTSLPPSLSECTHLELLRIAAN
RLQLLPDWLLTLPRLSWLAFAGNPFSDANEAASLARHSLPAIARAQVILHEQLGQGASGVIHRAQWQVSGQAPRPMAAKL
FKGHVTSDGLPHSEMAACVAAGRHANLIDVAGPLADHAELTPGLLMDLVDPGFQPLAGPPSLASCTRDSYGAEQRFSLEQ
VLRIASGVASAVAHLHRRGILHGDLYAHNLLVDPSGACLLSDFGAASFFEPDSAAGQRLKRIEARAFGCLLEELLQRCPD
TDPRQHVLLDLQRHCLNDNIEQRPDFDRLHSLLAAL

Sequences:

>Translated_436_residues
MHTLEQLERGELAGISRLDLSAGLDAFPDAIFGLADTLEVLNLSGNQLDSLPADLSRLRKLRILFCSDNPFTEVPECLGD
CPQLEMVGFKANRIRHLPADSLPPALRWLILTDNQLESLPDEIGNCRRLQKLMLAGNRLTSLPPSLSECTHLELLRIAAN
RLQLLPDWLLTLPRLSWLAFAGNPFSDANEAASLARHSLPAIARAQVILHEQLGQGASGVIHRAQWQVSGQAPRPMAAKL
FKGHVTSDGLPHSEMAACVAAGRHANLIDVAGPLADHAELTPGLLMDLVDPGFQPLAGPPSLASCTRDSYGAEQRFSLEQ
VLRIASGVASAVAHLHRRGILHGDLYAHNLLVDPSGACLLSDFGAASFFEPDSAAGQRLKRIEARAFGCLLEELLQRCPD
TDPRQHVLLDLQRHCLNDNIEQRPDFDRLHSLLAAL
>Mature_436_residues
MHTLEQLERGELAGISRLDLSAGLDAFPDAIFGLADTLEVLNLSGNQLDSLPADLSRLRKLRILFCSDNPFTEVPECLGD
CPQLEMVGFKANRIRHLPADSLPPALRWLILTDNQLESLPDEIGNCRRLQKLMLAGNRLTSLPPSLSECTHLELLRIAAN
RLQLLPDWLLTLPRLSWLAFAGNPFSDANEAASLARHSLPAIARAQVILHEQLGQGASGVIHRAQWQVSGQAPRPMAAKL
FKGHVTSDGLPHSEMAACVAAGRHANLIDVAGPLADHAELTPGLLMDLVDPGFQPLAGPPSLASCTRDSYGAEQRFSLEQ
VLRIASGVASAVAHLHRRGILHGDLYAHNLLVDPSGACLLSDFGAASFFEPDSAAGQRLKRIEARAFGCLLEELLQRCPD
TDPRQHVLLDLQRHCLNDNIEQRPDFDRLHSLLAAL

Specific function: Unknown

COG id: COG4886

COG function: function code S; Leucine-rich repeat (LRR) protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI6912638, Length=162, Percent_Identity=39.5061728395062, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI41281398, Length=162, Percent_Identity=36.4197530864198, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI34577083, Length=136, Percent_Identity=40.4411764705882, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI8923909, Length=159, Percent_Identity=34.5911949685535, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI55770895, Length=162, Percent_Identity=33.9506172839506, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI19923729, Length=179, Percent_Identity=33.5195530726257, Blast_Score=82, Evalue=7e-16,
Organism=Homo sapiens, GI95113664, Length=161, Percent_Identity=36.6459627329193, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI61742784, Length=169, Percent_Identity=39.6449704142012, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI61742786, Length=169, Percent_Identity=39.6449704142012, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI45827731, Length=188, Percent_Identity=35.6382978723404, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI45827729, Length=188, Percent_Identity=35.6382978723404, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI110825984, Length=177, Percent_Identity=34.4632768361582, Blast_Score=80, Evalue=5e-15,
Organism=Homo sapiens, GI16904383, Length=175, Percent_Identity=32, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI21361633, Length=226, Percent_Identity=29.646017699115, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI40217803, Length=185, Percent_Identity=31.3513513513514, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI21389431, Length=190, Percent_Identity=31.0526315789474, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI187829877, Length=225, Percent_Identity=27.1111111111111, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI62241040, Length=225, Percent_Identity=27.1111111111111, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI187829871, Length=225, Percent_Identity=27.1111111111111, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI33859670, Length=177, Percent_Identity=32.7683615819209, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI154091020, Length=189, Percent_Identity=31.7460317460317, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI256017180, Length=177, Percent_Identity=32.7683615819209, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI256017174, Length=177, Percent_Identity=32.7683615819209, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI238908508, Length=176, Percent_Identity=32.3863636363636, Blast_Score=73, Evalue=6e-13,
Organism=Homo sapiens, GI33285015, Length=148, Percent_Identity=37.8378378378378, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI122937315, Length=160, Percent_Identity=29.375, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI197333706, Length=177, Percent_Identity=28.8135593220339, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI34222199, Length=177, Percent_Identity=28.8135593220339, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI153792305, Length=130, Percent_Identity=34.6153846153846, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI194394161, Length=205, Percent_Identity=28.780487804878, Blast_Score=69, Evalue=7e-12,
Organism=Homo sapiens, GI190014581, Length=150, Percent_Identity=30, Blast_Score=67, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17552452, Length=203, Percent_Identity=35.9605911330049, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI71981160, Length=205, Percent_Identity=30.7317073170732, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71981152, Length=205, Percent_Identity=30.7317073170732, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71991531, Length=175, Percent_Identity=31.4285714285714, Blast_Score=75, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI71991525, Length=175, Percent_Identity=31.4285714285714, Blast_Score=75, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI71993778, Length=174, Percent_Identity=33.9080459770115, Blast_Score=73, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI71998900, Length=205, Percent_Identity=33.1707317073171, Blast_Score=72, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI71993783, Length=174, Percent_Identity=33.9080459770115, Blast_Score=72, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI71998904, Length=205, Percent_Identity=33.1707317073171, Blast_Score=72, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17550406, Length=167, Percent_Identity=32.3353293413174, Blast_Score=72, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17537883, Length=192, Percent_Identity=32.2916666666667, Blast_Score=71, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI25143890, Length=176, Percent_Identity=30.1136363636364, Blast_Score=70, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6322455, Length=165, Percent_Identity=30.9090909090909, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI281362653, Length=175, Percent_Identity=35.4285714285714, Blast_Score=85, Evalue=9e-17,
Organism=Drosophila melanogaster, GI19922294, Length=189, Percent_Identity=28.5714285714286, Blast_Score=85, Evalue=9e-17,
Organism=Drosophila melanogaster, GI24650334, Length=175, Percent_Identity=35.4285714285714, Blast_Score=85, Evalue=9e-17,
Organism=Drosophila melanogaster, GI24650332, Length=175, Percent_Identity=35.4285714285714, Blast_Score=85, Evalue=9e-17,
Organism=Drosophila melanogaster, GI281362651, Length=175, Percent_Identity=35.4285714285714, Blast_Score=85, Evalue=9e-17,
Organism=Drosophila melanogaster, GI24650330, Length=175, Percent_Identity=35.4285714285714, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI116007092, Length=175, Percent_Identity=35.4285714285714, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI62472958, Length=175, Percent_Identity=35.4285714285714, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI281362655, Length=175, Percent_Identity=35.4285714285714, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI281362657, Length=175, Percent_Identity=35.4285714285714, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24650336, Length=175, Percent_Identity=35.4285714285714, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI221379725, Length=162, Percent_Identity=32.0987654320988, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI221379722, Length=162, Percent_Identity=32.0987654320988, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI45550188, Length=133, Percent_Identity=38.3458646616541, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI19922706, Length=161, Percent_Identity=29.8136645962733, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI17933612, Length=217, Percent_Identity=32.258064516129, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI18858105, Length=178, Percent_Identity=30.8988764044944, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 47487; Mature: 47487

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: PS00107 PROTEIN_KINASE_ATP ; PS50011 PROTEIN_KINASE_DOM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHTLEQLERGELAGISRLDLSAGLDAFPDAIFGLADTLEVLNLSGNQLDSLPADLSRLRK
CCCHHHHHCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCHHCCHHHHHHHHH
LRILFCSDNPFTEVPECLGDCPQLEMVGFKANRIRHLPADSLPPALRWLILTDNQLESLP
EEEEEECCCCCHHHHHHHCCCCCEEEECCCHHHHCCCCCCCCCHHHEEEEECCCHHHHHH
DEIGNCRRLQKLMLAGNRLTSLPPSLSECTHLELLRIAANRLQLLPDWLLTLPRLSWLAF
HHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
AGNPFSDANEAASLARHSLPAIARAQVILHEQLGQGASGVIHRAQWQVSGQAPRPMAAKL
CCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHEEEECCCCCCHHHHHH
FKGHVTSDGLPHSEMAACVAAGRHANLIDVAGPLADHAELTPGLLMDLVDPGFQPLAGPP
HHCCCCCCCCCHHHHHHHHHCCCCCCCHHHCCCCHHHHHCCHHHHHHHHCCCCCCCCCCC
SLASCTRDSYGAEQRFSLEQVLRIASGVASAVAHLHRRGILHGDLYAHNLLVDPSGACLL
CHHHHHHHCCCCHHHHCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCEEEECCCCCEEE
SDFGAASFFEPDSAAGQRLKRIEARAFGCLLEELLQRCPDTDPRQHVLLDLQRHCLNDNI
ECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCC
EQRPDFDRLHSLLAAL
CCCCCHHHHHHHHHCC
>Mature Secondary Structure
MHTLEQLERGELAGISRLDLSAGLDAFPDAIFGLADTLEVLNLSGNQLDSLPADLSRLRK
CCCHHHHHCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCHHCCHHHHHHHHH
LRILFCSDNPFTEVPECLGDCPQLEMVGFKANRIRHLPADSLPPALRWLILTDNQLESLP
EEEEEECCCCCHHHHHHHCCCCCEEEECCCHHHHCCCCCCCCCHHHEEEEECCCHHHHHH
DEIGNCRRLQKLMLAGNRLTSLPPSLSECTHLELLRIAANRLQLLPDWLLTLPRLSWLAF
HHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
AGNPFSDANEAASLARHSLPAIARAQVILHEQLGQGASGVIHRAQWQVSGQAPRPMAAKL
CCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHEEEECCCCCCHHHHHH
FKGHVTSDGLPHSEMAACVAAGRHANLIDVAGPLADHAELTPGLLMDLVDPGFQPLAGPP
HHCCCCCCCCCHHHHHHHHHCCCCCCCHHHCCCCHHHHHCCHHHHHHHHCCCCCCCCCCC
SLASCTRDSYGAEQRFSLEQVLRIASGVASAVAHLHRRGILHGDLYAHNLLVDPSGACLL
CHHHHHHHCCCCHHHHCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCEEEECCCCCEEE
SDFGAASFFEPDSAAGQRLKRIEARAFGCLLEELLQRCPDTDPRQHVLLDLQRHCLNDNI
ECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCC
EQRPDFDRLHSLLAAL
CCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA